In addition to slow intravenous infusion, which of the following routes of administration allows for titration of the dose of a drug with the response: A. Sublingual B. Transdermal C. Inhalational D. Nasal insufflation

In addition to slow intravenous infusion, which of the
following routes of administration allows for titration of
the dose of a drug with the response:
A. Sublingual
B. Transdermal
C. Inhalational
D. Nasal insufflation
by

1 Answer

Answer :

C. Inhalational
by

Related questions

In addition to slow intravenous infusion, which of the following routes of administration allows for titration of the dose of a drug with the response: A. Sublingual B. Transdermal C. Inhalational D. Nasal insufflation

Description : In addition to slow intravenous infusion, which of the following routes of administration allows for titration of the dose of a drug with the response: A. Sublingual B. Transdermal C. Inhalational D. Nasal insufflation

Last Answer : C. Inhalational

A patient of acute myocardial infarction being treated in intensive care unit developed left ventricular failure with raised central venous pressure. It was decided to use glyceryl trinitrate. Which route/method of administration would be most suitable. (a) Sublingual (b) Oral (c) Intravenous bolus injection (d) Slow intravenous infusion

Description : A patient of acute myocardial infarction being treated in intensive care unit developed left ventricular failure with raised central venous pressure. It was decided to use glyceryl trinitrate. Which route/ ... (a) Sublingual (b) Oral (c) Intravenous bolus injection (d) Slow intravenous infusion

Last Answer : Ans: D

A patient of acute myocardial infarction being treated in intensive care unit developed left ventricular failure with raised central venous pressure. It was decided to use glyceryl trinitrate. Which route/method of administration would be most suitable: A. Sublingual B. Oral C. Intravenous bolus injection D. Slow intravenous infusion

Description : A patient of acute myocardial infarction being treated in intensive care unit developed left ventricular failure with raised central venous pressure. It was decided to use glyceryl trinitrate. Which route ... suitable: A. Sublingual B. Oral C. Intravenous bolus injection D. Slow intravenous infusion

Last Answer : D. Slow intravenous infusion

Noradrenaline is administered by (a) Subcutaneous injection (b) Intramuscular injection (c) Slow intravenous infusion (d) All of the above routes

Description : Noradrenaline is administered by (a) Subcutaneous injection (b) Intramuscular injection (c) Slow intravenous infusion (d) All of the above routes

Last Answer : Ans: C

Noradrenaline is administered by: A. Subcutaneous injection B. Intramuscular injection C. Slow intravenous infusion D. All of the above routes

Description : Noradrenaline is administered by: A. Subcutaneous injection B. Intramuscular injection C. Slow intravenous infusion D. All of the above routes

Last Answer : C. Slow intravenous infusion

Noradrenaline is administered by: A. Subcutaneous injection B. Intramuscular injection C. Slow intravenous infusion D. All of the above routes

Description : Noradrenaline is administered by: A. Subcutaneous injection B. Intramuscular injection C. Slow intravenous infusion D. All of the above routes

Last Answer : C. Slow intravenous infusion

Thrombolytic therapy has become a useful adjunct in the management of peripheral arterial occlusion. In this setting, direct intraarterial administration rather than intravenous has been advocated to decrease the risk of systemic bleeding. Which of the following true statement(s) concerning the use of thrombolytic agents for arterial occlusion is/are true? a. A standard technique involves infusing high-dose urokinase, 4000 units per minute for 1–2 hours, directly into the clot by a catheter embedded in the thrombus b. If progress is made, further fibrinolytic therapy is given at 1000 to 2000 units per minute until clot lysis has occurred c. The usual infusion time by the above-stated technique is usually in excess of 24 hours d. Successful clot lysis occurs more frequently in arterial graf

Description : Thrombolytic therapy has become a useful adjunct in the management of peripheral arterial occlusion. In this setting, direct intraarterial administration rather than intravenous has been advocated ... may be indicated for situations where complete clot evacuation cannot be accomplished surgically

Last Answer : Answer: a, b, e The most popular method for intraarterial thrombolytic therapy for arterial occlusion involves passing a guidewire through the thrombus with arteriographic guidance and ... acute arterial occlusion) or when distal vasculative is occluded and precludes appropriate inflow patency

11. Which route of drug administration is most likely to lead to the first-pass effect? a) Sublingual b) Oral c) Intravenous d) Intramuscular

Description : 11. Which route of drug administration is most likely to lead to the first-pass effect? a) Sublingual b) Oral c) Intravenous d) Intramuscular

Last Answer : b) Oral

A semiconscious patient of haemorrhagic cerebral stroke has been brought to the emergency. His blood pressure is 240/120 mmHg. Select the procedure to lower his blood pressure as rapidly as possible: A. Sublingual nifedipine B. Intramuscular injection of hydralazine C. Intravenous infusion of sodium nitroprusside D. Intravenous injection of clonidin

Description : A semiconscious patient of haemorrhagic cerebral stroke has been brought to the emergency. His blood pressure is 240/120 mmHg. Select the procedure to lower his blood pressure as ... injection of hydralazine C. Intravenous infusion of sodium nitroprusside D. Intravenous injection of clonidin

Last Answer : C. Intravenous infusion of sodium nitroprussid

The following procedure for rapid lowering of BP in hypertensive urgency/emergency has been abandoned: A. Sublingual/oral nifedipine B. Intravenous glyceryl trinitrate infusion C. Intravenous sodium nitroprusside infusion D. Intravenous esmolol injection

Description : The following procedure for rapid lowering of BP in hypertensive urgency/emergency has been abandoned: A. Sublingual/oral nifedipine B. Intravenous glyceryl trinitrate infusion C. Intravenous sodium nitroprusside infusion D. Intravenous esmolol injection

Last Answer : A. Sublingual/oral nifedipine

The preferred route of administration of medication in the most acute care situations is which of the following routes? a) Intravenous The IV route is the preferred parenteral route in most acute care situations because it is much more comfortable for the patient, and peak serum levels and pain relief occur more rapidly and reliably. b) Epidural Epidural administration is used to control postoperative and chronic pain. c) Subcutaneous Subcutaneous administration results in slow absorption of medication. d) Intramuscular Intramuscular administration of medication is absorbed more slowly than intravenously administered medication.

Description : The preferred route of administration of medication in the most acute care situations is which of the following routes? a) Intravenous The IV route is the preferred ... ) Intramuscular Intramuscular administration of medication is absorbed more slowly than intravenously administered medication.

Last Answer : a) Intravenous The IV route is the preferred parenteral route in most acute care situations because it is much more comfortable for the patient, and peak serum levels and pain relief occur more rapidly and reliably.

Transdermal drug delivery systems offer the following advantages except: A. They produce high peak plasma concentration of the drug B. They produce smooth and nonfluctuating plasma concentration of the drug C. They minimise interindividual variations in the achieved plasma drug concentration D. They avoid hepatic first-pass metabolism of the drug

Description : Transdermal drug delivery systems offer the following advantages except: A. They produce high peak plasma concentration of the drug B. They produce smooth and nonfluctuating plasma concentration of the ... the achieved plasma drug concentration D. They avoid hepatic first-pass metabolism of the drug

Last Answer : A. They produce high peak plasma concentration of the drug

Transdermal drug delivery systems offer the following advantages except: A. They produce high peak plasma concentration of the drug B. They produce smooth and nonfluctuating plasma concentration of the drug C. They minimise interindividual variations in the achieved plasma drug concentration D. They avoid hepatic first-pass metabolism of the drug

Description : Transdermal drug delivery systems offer the following advantages except: A. They produce high peak plasma concentration of the drug B. They produce smooth and nonfluctuating plasma concentration of the ... the achieved plasma drug concentration D. They avoid hepatic first-pass metabolism of the drug

Last Answer : A

Glyceryl trinitrate is administratered by all of the following routes except (a) Oral (b) Sublingual (c) Intramuscular (d) Intravenous

Description : Glyceryl trinitrate is administratered by all of the following routes except (a) Oral (b) Sublingual (c) Intramuscular (d) Intravenous

Last Answer : Ans: C

Glyceryl trinitrate is administered by the following routes except: A. Oral B. Sublingual C. Intramuscular D. Intravenous

Description : Glyceryl trinitrate is administered by the following routes except: A. Oral B. Sublingual C. Intramuscular D. Intravenous

Last Answer : C. Intramuscular

The most appropriate route of administration for adrenaline in a case of anaphylactic shock is: A. Intracardiac B. Intravenous C. Intramuscular D. Subcutaneous

Description : The most appropriate route of administration for adrenaline in a case of anaphylactic shock is: A. Intracardiac B. Intravenous C. Intramuscular D. Subcutaneous

Last Answer : A. Intracardiac

Select the route of administration which carries the highest risk of adversely affecting vital functions: A. Intra arterial injection B. Intrathecal injection C. Intravenous injection D. Intramuscular injection

Description : Select the route of administration which carries the highest risk of adversely affecting vital functions: A. Intra arterial injection B. Intrathecal injection C. Intravenous injection D. Intramuscular injection

Last Answer : C. Intravenous injection

Select the route of administration which carries the highest risk of adversely affecting vital functions: A. Intra arterial injection B. Intrathecal injection C. Intravenous injection D. Intramuscular injection

Description : Select the route of administration which carries the highest risk of adversely affecting vital functions: A. Intra arterial injection B. Intrathecal injection C. Intravenous injection D. Intramuscular injection

Last Answer : C. Intravenous injection

Drug administered through the following route is most likely to be subjected to first-pass metabolism: A. Oral B. Sublingual C. Subcutaneous D. Rectal

Description : Drug administered through the following route is most likely to be subjected to first-pass metabolism: A. Oral B. Sublingual C. Subcutaneous D. Rectal

Last Answer : A. Oral

Drug administered through the following route is most likely to be subjected to first-pass metabolism: A. Oral B. Sublingual C. Subcutaneous D. Rectal

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Last Answer : A. Oral

A drug which does not produce any action by itself but decreases the slope of the log dose-response curve and suppresses the maximal response to another drug is a: A. Physiological antagonist B. Competitive antagonist C. Noncompetitive antagonist D. Partial agonist

Description : A drug which does not produce any action by itself but decreases the slope of the log dose-response curve and suppresses the maximal response to another drug is a: A. Physiological antagonist B. Competitive antagonist C. Noncompetitive antagonist D. Partial agonist

Last Answer : C. Noncompetitive antagonist

A drug ‘R’ producing no response by itself causes the log dose-response curve of another drug ‘S’ to shift to the right in a parallel manner without decreasing the maximal response: Drug ‘R’ is a: A. Partial agonist B. Inverse agonist C. Competitive antagonist D. Noncompetitive antagonist

Description : A drug ‘R’ producing no response by itself causes the log dose-response curve of another drug ‘S’ to shift to the right in a parallel manner without decreasing the maximal response: Drug ‘R’ is a: A. Partial agonist B. Inverse agonist C. Competitive antagonist D. Noncompetitive antagonist

Last Answer : C. Competitive antagonist

If the dose-response curves of a drug for producing different actions are widely separated on the dose axis, the drug is: A. Highly potent B. Highly efficacious C. Highly toxic D. Highly selective

Description : If the dose-response curves of a drug for producing different actions are widely separated on the dose axis, the drug is: A. Highly potent B. Highly efficacious C. Highly toxic D. Highly selective

Last Answer : D. Highly selective

‘Drug efficacy’ refers to: A. The range of diseases in which the drug is beneficial B. The maximal intensity of response that can be produced by the drug C. The dose of the drug needed to produce half maximal effect D. The dose of the drug needed to produce therapeutic effect

Description : ‘Drug efficacy’ refers to: A. The range of diseases in which the drug is beneficial B. The maximal intensity of response that can be produced by the drug C. The dose of the drug needed to produce half maximal effect D. The dose of the drug needed to produce therapeutic effect

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The following statement is not true of ‘potency’ of a drug: A. Refers to the dose of the drug needed to produce a certain degree of response B. Can be related to that of its congeners by the relative position of its dose-response curve on the dose axis C. It is often not a major consideration in the choice of a drug D. It reflects the capacity of the drug to produce a drastic response

Description : The following statement is not true of potency' of a drug: A. Refers to the dose of the drug needed to produce a certain degree of response B. Can be related to that of its congeners by ... consideration in the choice of a drug D. It reflects the capacity of the drug to produce a drastic response

Last Answer : D. It reflects the capacity of the drug to produce a drastic response

A drug which does not produce any action by itself but decreases the slope of the log dose-response curve and suppresses the maximal response to another drug is a: A. Physiological antagonist B. Competitive antagonist C. Noncompetitive antagonist D. Partial agonist

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Last Answer : C. Noncompetitive antagonist

A drug ‘R’ producing no response by itself causes the log dose-response curve of another drug ‘S’ to shift to the right in a parallel manner without decreasing the maximal response: Drug ‘R’ is a: A. Partial agonist B. Inverse agonist C. Competitive antagonist D. Noncompetitive antagonist

Description : A drug ‘R’ producing no response by itself causes the log dose-response curve of another drug ‘S’ to shift to the right in a parallel manner without decreasing the maximal response: Drug ‘R’ is a: A. Partial agonist B. Inverse agonist C. Competitive antagonist D. Noncompetitive antagonist

Last Answer : C. Competitive antagonist

If the dose-response curves of a drug for producing different actions are widely separated on the dose axis, the drug is: A. Highly potent B. Highly efficacious C. Highly toxic D. Highly selective

Description : If the dose-response curves of a drug for producing different actions are widely separated on the dose axis, the drug is: A. Highly potent B. Highly efficacious C. Highly toxic D. Highly selective

Last Answer : D. Highly selective

‘Drug efficacy’ refers to: A. The range of diseases in which the drug is beneficial B. The maximal intensity of response that can be produced by the drug C. The dose of the drug needed to produce half maximal effect D. The dose of the drug needed to produce therapeutic effect

Description : ‘Drug efficacy’ refers to: A. The range of diseases in which the drug is beneficial B. The maximal intensity of response that can be produced by the drug C. The dose of the drug needed to produce half maximal effect D. The dose of the drug needed to produce therapeutic effect

Last Answer : B. The maximal intensity of response that can be produced by the drug

The following statement is not true of ‘potency’ of a drug: A. Refers to the dose of the drug needed to produce a certain degree of response B. Can be related to that of its congeners by the relative position of its dose-response curve on the dose axis C. It is often not a major consideration in the choice of a drug D. It reflects the capacity of the drug to produce a drastic response

Description : The following statement is not true of potency' of a drug: A. Refers to the dose of the drug needed to produce a certain degree of response B. Can be related to that of its congeners by ... consideration in the choice of a drug D. It reflects the capacity of the drug to produce a drastic response

Last Answer : D. It reflects the capacity of the drug to produce a drastic response

A drug which produces qualitatively different actions when administered through different routes is: A. Phenytoin sodium B. Hydralazine C. Magnesium sulfate D. Nitroglycerine

Description : A drug which produces qualitatively different actions when administered through different routes is: A. Phenytoin sodium B. Hydralazine C. Magnesium sulfate D. Nitroglycerine

Last Answer : C. Magnesium sulfate

A nonvolatile, highly lipid soluble drug is metabolized at a rate of 15% per hour. On intravenous injection it produces general anaesthesia for 10 min. Which process is responsible for termination of its action: A. Metabolism in liver B. Plasma protein binding C. Excretion by kidney D. Redistribution

Description : A nonvolatile, highly lipid soluble drug is metabolized at a rate of 15% per hour. On intravenous injection it produces general anaesthesia for 10 min. Which process is responsible for termination of ... : A. Metabolism in liver B. Plasma protein binding C. Excretion by kidney D. Redistribution

Last Answer : D. Redistribution

In an anaesthetized dog, repeated intravenous injection of ephedrine shows the phenomenon of: A. Anaphylaxis B. Tachyphylaxis C. Idiosyncrasy D. Drug resistance

Description : In an anaesthetized dog, repeated intravenous injection of ephedrine shows the phenomenon of: A. Anaphylaxis B. Tachyphylaxis C. Idiosyncrasy D. Drug resistance

Last Answer : B. Tachyphylaxis

A nonvolatile, highly lipid soluble drug is metabolized at a rate of 15% per hour. On intravenous injection it produces general anaesthesia for 10 min. Which process is responsible for termination of its action: A. Metabolism in liver B. Plasma protein binding C. Excretion by kidney D. Redistribution

Description : A nonvolatile, highly lipid soluble drug is metabolized at a rate of 15% per hour. On intravenous injection it produces general anaesthesia for 10 min. Which process is responsible for termination of ... : A. Metabolism in liver B. Plasma protein binding C. Excretion by kidney D. Redistribution

Last Answer : D. Redistribution

A drug (200 mg dose) administered in tablet form and as intravenous injection (50 mg dose) showed AUG of 100 and 200 microgram hr/mL, respectively. The absolute availability of the drug through oral administration is : (A) 125% (B) 250 % (C) 12.5% (D) 1.25%

Description : A drug (200 mg dose) administered in tablet form and as intravenous injection (50 mg dose) showed AUG of 100 and 200 microgram hr/mL, respectively. The absolute availability of the drug through oral administration is : (A) 125% (B) 250 % (C) 12.5% (D) 1.25%

Last Answer : (C) 12.5%

Select the vasodilator that is administered only by slow intravenous infusion and dilates both resistance as well as capacitance vessels: A. Minoxidil B. Diazoxide C. Sodium nitroprusside D. Glyceryl trinitrate

Description : Select the vasodilator that is administered only by slow intravenous infusion and dilates both resistance as well as capacitance vessels: A. Minoxidil B. Diazoxide C. Sodium nitroprusside D. Glyceryl trinitrate

Last Answer : C. Sodium nitroprusside

The following statement is not true of log dose-response curve: A. It is almost linear except at the ends B. It is a rectangular hyperbola C. It facilitates comparison of different agonists D. It can help in discriminating between competitive and noncompetitive antagonists

Description : The following statement is not true of log dose-response curve: A. It is almost linear except at the ends B. It is a rectangular hyperbola C. It facilitates comparison of different agonists D. It can help in discriminating between competitive and noncompetitive antagonists

Last Answer : B. It is a rectangular hyperbola

Which of the following constitutes ‘drug abuse’: A. Physician prescribed use of penicillin G for the cure of viral fever B. Self administration of aspirin to relieve headache C. Repeated self administration of morphine to derive euphoria D. All of the above

Description : Which of the following constitutes ‘drug abuse’: A. Physician prescribed use of penicillin G for the cure of viral fever B. Self administration of aspirin to relieve headache C. Repeated self administration of morphine to derive euphoria D. All of the above

Last Answer : D. Differ from each other in the degree of attendant psychological dependence

Adaptive neurophysiological changes produced by repeated administration of a drug, which result in the appearance of characteristic withdrawal syndrome on discontinuation of the drug is called: A. Drug addiction B. Drug abuse C. Psychological dependence D. Physical dependence

Description : Adaptive neurophysiological changes produced by repeated administration of a drug, which result in the appearance of characteristic withdrawal syndrome on discontinuation of the drug is called: A. Drug addiction B. Drug abuse C. Psychological dependence D. Physical dependence

Last Answer : D. Physical dependence

Nitrate tolerance is least likely to develop with the use of: A. Sustained release oral glyceryl trinitrate B. Sublingual glyceryl trinitrate C. Transdermal glyceryl trinitrate D. Oral pentaerythritol tetranitrate

Description : Nitrate tolerance is least likely to develop with the use of: A. Sustained release oral glyceryl trinitrate B. Sublingual glyceryl trinitrate C. Transdermal glyceryl trinitrate D. Oral pentaerythritol tetranitrate

Last Answer : B. Sublingual glyceryl trinitrate

Reflex bronchoconstriction is most likely to occur with the following form of inhaled antiasthma medication: A. Metered dose spray of drug in solution B. Dry powder rotacap C. Nebuliser D. Nebuliser with spacer

Description : Reflex bronchoconstriction is most likely to occur with the following form of inhaled antiasthma medication: A. Metered dose spray of drug in solution B. Dry powder rotacap C. Nebuliser D. Nebuliser with spacer

Last Answer : B. Dry powder rotacap

A ‘toxic effect’ differs from a ‘side effect’ in that: A. It is not a pharmacological effect of the drug B. It is a more intense pharmacological effect that occurs at high dose or after prolonged medication C. It must involve drug induced cellular injury D. It involves host defence mechanisms

Description : A ‘toxic effect’ differs from a ‘side effect’ in that: A. It is not a pharmacological effect of the drug B. It is a more intense pharmacological effect that occurs at high dose or after prolonged medication C. It must involve drug induced cellular injury D. It involves host defence mechanisms

Last Answer : B. It is a more intense pharmacological effect that occurs at high dose or after prolonged medication

The therapeutic index of a drug is a measure of its: A. Safety B. Potency C. Efficacy D. Dose variability

Description : The therapeutic index of a drug is a measure of its: A. Safety B. Potency C. Efficacy D. Dose variability

Last Answer : A. Safety

The loading dose of a drug is governed by its: A. Renal clearance B. Plasma half life C. Volume of distribution D. Elimination rate constant

Description : The loading dose of a drug is governed by its: A. Renal clearance B. Plasma half life C. Volume of distribution D. Elimination rate constant

Last Answer : C. Volume of distribution

When the same dose of a drug is repeated at half life intervals, the steady-state (plateau) plasma drug concentration is reached after: A. 2–3 half lives B. 4–5 half lives C. 6–7 half lives D. 8–10 half lives

Description : When the same dose of a drug is repeated at half life intervals, the steady-state (plateau) plasma drug concentration is reached after: A. 2–3 half lives B. 4–5 half lives C. 6–7 half lives D. 8–10 half lives

Last Answer : B. 4–5 half lives

If the clearance of a drug remains constant, doubling the dose rate will increase the steady-state plasma drug concentration by a factor of: A. × 3 B. × 2 C. × 1.5 D. × 1.3

Description : If the clearance of a drug remains constant, doubling the dose rate will increase the steady-state plasma drug concentration by a factor of: A. × 3 B. × 2 C. × 1.5 D. × 1.3

Last Answer : B. × 2

Bioavailability of drug refers to: A. Percentage of administered dose that reaches systemic circulation in the unchanged form B. Ratio of oral to parenteral dose C. Ratio of orally administered drug to that excreted in the faeces D. Ratio of drug excreted unchanged in urine to that excreted as metabolites

Description : Tricyclic antidepressants can alter the oral absorption of many drugs by: A. Complexing with the other drug in the intestinal lumen B. Altering gut motility C. Altering gut flora D. Damaging gut mucosa

Last Answer : C. Altering gut flora

Bioavailability of drug refers to: A. Percentage of administered dose that reaches systemic circulation in the unchanged form B. Ratio of oral to parenteral dose C. Ratio of orally administered drug to that excreted in the faeces D. Ratio of drug excreted unchanged in urine to that excreted as metabolites

Description : Bioavailability of drug refers to: A. Percentage of administered dose that reaches systemic circulation in the unchanged form B. Ratio of oral to parenteral dose C. Ratio of orally administered drug to ... in the faeces D. Ratio of drug excreted unchanged in urine to that excreted as metabolites

Last Answer : A. Percentage of administered dose that reaches systemic circulation in the unchanged form

A ‘toxic effect’ differs from a ‘side effect’ in that: A. It is not a pharmacological effect of the drug B. It is a more intense pharmacological effect that occurs at high dose or after prolonged medication C. It must involve drug induced cellular injury D. It involves host defence mechanisms

Description : A ‘toxic effect’ differs from a ‘side effect’ in that: A. It is not a pharmacological effect of the drug B. It is a more intense pharmacological effect that occurs at high dose or after prolonged medication C. It must involve drug induced cellular injury D. It involves host defence mechanisms

Last Answer : B. It is a more intense pharmacological effect that occurs at high dose or after prolonged medication

A fixed dose combination preparation meant for internal use must not contain the following class of drug: A. Thiazide diuretic B. Fluoroquinolone antimicrobial C. Corticosteroid D. H2 blocker

Description : A fixed dose combination preparation meant for internal use must not contain the following class of drug: A. Thiazide diuretic B. Fluoroquinolone antimicrobial C. Corticosteroid D. H2 blocker

Last Answer : C. Corticosteroid