Description : To separate macrophages from a mouse -Biology
Last Answer : answer:
Description : Which organ is considered as "Graveyard of RBC" where most of them are destroyed by macrophages Which of the following organs can be called as a sort
Last Answer : Which organ is considered as "Graveyard of RBC" where most of them are destroyed by macrophages Which of the ... A. Heart B. Liver C. Spleen D. Lungs
Description : Macrophages of spleen are :-
Last Answer : Macrophages of spleen are :- A. Microgleal cell B. Dust cell C. Reticular cell D. Monocyte cell
Description : MHC class II proteins are present on the surface of (A) All cells (B) B lymphocytes only (C) Macrophages only (D) Macrophages and B lymphocytes
Last Answer : Answer : D
Description : MHC class I proteins are present on the surface of (A) B cells only (B) T cells only (C) Macrophages only(D) All cells
Description : Which of the following statement(s) is/are true concerning ischemia reperfusion injury? a. During ischemia, ATP degradation results in increased plasma and intracellular levels of ... immunization with antibodies to neutrophil adhesive complex lessen the ischemic/reperfusion microvascular injury
Last Answer : Answer: a, b, c, d During the ischemia and hypoperfusion phase, degradation of ATP stores essential to maintain cell integrity and significant loss of diffusible ... either the neutrophil adhesive complex or the endothelial selectins dramatically lessens ischemia/reperfusion microvascular injury
Description : Which of the following statement(s) is/are true concerning tumor necrosis factor (TNF)? a. TNF is a product of activated macrophages secreted in response to contact with endotoxin or ... completed clinical trials of anti-TNF antibody in septic patients shows a marked improvement in survival
Last Answer : Answer: a, b Tumor necrosis factor (TNF), a protein product of activated macrophages, is secreted in response to contact with endotoxin or lipopolysaccharide, antibody complexes, or ... patients utilizing infusion of monoclonal antibodies to the TNF molecule have shown no overall survival benefit
Description : The initiation of a humoral immune response involves a complex interaction of the antigen, cells and intercellular messengers. Which of the following statement(s) concerning the initiation of the ... various cellular components of the immune system d. An antigen must be a living microorganism
Last Answer : Answer: a, b Stimulation of the immune system occurs after a variety of antigen-presenting cells (B lymphocytes, macrophages, dendritic cells, and Langerhans cells) act to engulf ... polysaccharides), most antigens require coordinated efforts of the various cellular components of the immune system
Description : The following statement(s) is/are true concerning cellular defense mechanisms. a. Macrophages function solely as antigen processing cells in the initial reaction to exposure to an antigen b. Macrophages ... in only small numbers within the tissue and enter an area of infection through diapedesis
Last Answer : Answer: b, d A wide variety of cell types serve to provide host defense at several levels. Macrophages act as the initial antigen processing cell that serves to ... through diapedesis after chemotactic stimuli are excluded by macrophages, bacterial breakdown products, and complement activation
Description : Cytokines are low-molecular-weight polypeptides exerting a wide variety of biologic effects at both local and systemic levels. Which of the following statement(s) is/are true concerning the production and ... effects on the host d. Each specific cytokine is produced by a single cell type
Last Answer : Answer: c Macrophages, endothelial cells, lymphocytes, and other cells secrete a large number of different compounds, termed cytokines, that are most probably evolved for the purpose of ... host defenses, exerting both salutatory and deleterious effects on the host, has become increasingly evident
Description : Increasing evidence has implicated gram-negative bacterial lipopolysaccharide (LPS endotoxin) as the portion of the gram-negative bacterial cell membrane responsible for many, if not all the ... host, exerting deleterious effects on the host when excessive amounts reach the systemic circulation
Last Answer : Answer: a, b, d The LPS molecule exerts diverse effects on the mammalian host. Immunologic responses to LPS include nonspecific polyclonal B-cell proliferation, macrophage activation and ... deleterious effects on the host only after large amounts are secreted and reach the systemic circulation
Description : Which of the following statement(s) is/are true about the role of macrophages in the wound healing process? a. Macrophages are the dominant cell type during the inflammatory phase of wound ... phagocytosis d. Macrophages are a source of a number of humoral factors essential for wound healing
Last Answer : Answer: a, d Within three or four days after injury, macrophages become the dominant cell type in the inflammatory phase of wound healing. The role of macrophages is not limited only ... . These studies confirm the dominant role of the macrophage and the inflammatory phase of wound healing
Description : Which of the following statement(s) is/are true concerning the cell function of phagocytosis? a. Phagocytosis is a mechanistically distinct process of endocytosis performed by special cells to take ... known as clathrin d. Phagocytosis is performed only by white blood cells and tissue macrophages
Last Answer : Answer: a Phagocytosis is a specialized form of endocytosis by which large particles are internalized by specialized cells primarily macrophages and neutrophils. To be phagocytosed, particles ... the lumen of the thyroid follicle, thereby releasing the thyroid hormones, thyroxine triiodothyronine
Description : Which of the following is/are true of the actions of transforming growth factor beta (TGF-b) during wound repair? A. Increased matrix and proteoglycan synthesis. B. Inhibition of proteases. ... of plasminogen inhibitor. D. Chemotaxis for fibroblasts and macrophages. E. Autoinduction of TGF-b.
Last Answer : Answer: ABDE DISCUSSION: Through autocrine and paracrine mechanisms TGF-b stimulates the deposition of collagen and other matrix components by fibroblasts, inhibits proteases, blocks plasminogen inhibitor, ... effects. The sustained production of TGF-b at the wound site leads to tissue fibrosis
Description : The cells that are directly concerned with phagocytosis of foreign bodies in the reticuloendothelial system are (a) reticular cells (b) monocytes (c) eosinophils and Basophils (d) macrophages
Last Answer : Ans:(b)
Description : In our body, antibodies are formed against pathogens in – (1) liver by RBC (2) blood by platelets (3) brain by macrophages (4) thymus by lymphocytes
Last Answer : (4) thymus by lymphocytes
Description : The function of macrophages is to
Last Answer : ingest the micro-organisms.
Description : In case of infection, following is the first line of defense B A. Antibodies B. Macrophages C. Red blood cells D. Platelets
Last Answer : Macrophages
Description : In case of infection, following is the first line of defense B A. Antibodies B. Macrophages C. Red blood cells D. Platelet
Description : The following are true about atherosclerosis: C A. it often occurs in the heart chamber B. foamy macrophages are not seen in the lesion C. smooth muscle cells proliferation in the intima of vessel D. no deposition of lipid occurs in wall of blood vessel
Last Answer : smooth muscle cells proliferation in the intima of vessel
Description : Predominant cell types in typical chronic inflammation are all of the following EXCEPT: A A. Polymorphonuclear leukocytes B. Macrophages C. T helper lymphocytes D. NK cells
Last Answer : Polymorphonuclear leukocytes
Description : Epithelioid cells within granulomas are derived from which of the following? B A. Plasma cells B. Macrophages C. Lymphocytes D. Neutrophils
Description : Reactive oxygen metabolites are produced by all the following EXCEPT: B A. Macrophages B. Lymphocytes C. Monocytes D. None of these
Last Answer : Lymphocytes
Description : Upon activation, macrophages release all of the following from granules EXCEPT C A. Collagenase B. Elastase C. Cathepsins D. None of these
Last Answer : Cathepsins
Description : Tissue macrophages are derived from which one of the following? A. Resident activated fibroblasts B. Activated B lymphocytes C. Circulating monocytes D. Platelets
Last Answer : Platelets
Description : Predominant cell types in typical chronic inflammatory reactions include all of the following EXCEPT: A A. Polymorphonuclear leukocytes B. Macrophages C. T helper lymphocytes D. None of these
Description : Epithelioid cells within granulomas are derived from which of the following? B A. Plasma cells B. Macrophages C. Lymphocytes D. None of these
Description : Heart failure cells, i.e.. macrophages loaded with haemosiderin, are most likely found in C A. Ascites fluid in congestive heart failure B. Pulmonary alveoli in mitral stenosis C. Left ventricular myocardium following infarction and reperfusion D. None of these
Last Answer : Ascites fluid in congestive heart failure B. Pulmonary alveoli in mitral stenosis C. Left ventricul
Description : Early granulation tissue is BEST characterized by the presence of: C A. Plasma cells and macrophages B. T lymphocytes and eosinophils C. Capillary buds and fibroblasts D. None of these
Last Answer : Capillary buds and fibroblast
Description : Which one of the following are cardinal features of granulation tissue? C A. Abundant collagen B. Proliferating macrophages and lymphocytes C. Proliferating capillaries and fibroblasts D. None of these
Last Answer : Proliferating capillaries and fibroblasts
Description : Colostrum, the yellowish fluid, secreted by mother during the initial days of lactation is very essential to impart immunity to the new born infants because it contains (a) immunoglobulin A (b) natural killer cells (c) monocytes (d) macrophages.
Last Answer : (a) immunoglobulin A
Description : The most active phagocytic white blood cells are (a) eosinophils and lymphocytes (b) neutrophils and monocytes (c) neutrophils and eosinophils (d) lymphocytes and macrophages.
Last Answer : (b) neutrophils and monocytes
Description : Immunosuppressive agents used in preventing transplant rejection primarily affect a. macrophages. b. neutrophils. c. dendritic cells. d. T cells.
Last Answer : d. T cells.
Description : In the body's immune system, _____ are the major producers of secreted antibodies. a. macrophages b. plasma cells c. T cells d. B cells
Last Answer : b. plasma cells
Description : TH1 cells activate a. B cells. b. Killing of pathogens in macrophages. c. Cytotoxic T cells. d. Humoral immunity.
Last Answer : d. Humoral immunity
Description : . MHC class I proteins would be found on___________ whereas MHC class II proteins would be found on_____________ a. Nucleated Cells; Plasma Cells b. Nucleated Cells; Macrophages c. Dendritic Cells; Neutrophils d. Only White Blood Cells; Red Blood Cells
Last Answer : b. Nucleated Cells; Macrophages
Description : A _____ is a protein receptor on the surface of macrophages, dendritic cells, and endothelial cells that allow them to recognize foreign cell markers. a. Toll-like receptor (TLR) b. pathogen-associated c. Membrane attack complex (MAC) d. Natural killer cells (NK)
Last Answer : b. pathogen-associated
Description : Which of the following is a cellular barrier in the innate defense system? a. macrophages b. Erythrocytes c. B-cells d. T-cells
Last Answer : a. macrophages
Description : ________ bind to_________ on microbial invaders. a. Toll-like receptors; PAM Ps b. Mast cells; histamine c. Toll-like receptors; complement d. Macrophages; defensins
Last Answer : a. Toll-like receptors; PAM Ps
Description : Which of the following statements is not true regarding Mycobacterium tuberculosis and/or the disease it causes? A.The pathogen contains mycolic acid in its cell wall B.The pathogen can live inside macrophages C.Antibodies to the pathogen are protective D.None of these
Last Answer : C.Antibodies to the pathogen are protective
Description : Macrophages are professional antigen- presenting cells. The protein molecule through which theypresent antigen in human is A.actin B.interleukin C.HLA D.CD8
Last Answer : D.CD8
Description : The role of the M cell is to A- .trap virus in mucus and prevent entry B- induce apoptosis in virus-infected small intestinal epithelia cells C- pass bacteria or virus to underlying macrophages for ... and presentation of antigen D- they use their cilia to propel mucus out of the small intestine
Last Answer : pass bacteria or virus to underlying macrophages for processing and presentation of antigen
Description : Macrophages are professional antigen- presenting cells. The protein molecule through whichthey present antigen in human is A- actin B- nterleukin C- HLA D- .CD8
Last Answer : .CD8
Description : During which stage or phase of bone healing after fracture is devitalized tissue removed and new bone reorganized into its former structural arrangement? a) Remodeling Remodeling is the final stage of ... occurs during the reparative stage but is disrupted by excessive motion at the fracture site.
Last Answer : a) Remodeling Remodeling is the final stage of fracture repair.
Description : During which stage or phase of bone healing after fracture does callus formation occur? a) Reparative Callus formation occurs during the reparative stage but is disrupted by excessive motion ... the fracture area. d) Revascularization Revascularization occurs within about 5 days after the fracture.
Last Answer : a) Reparative Callus formation occurs during the reparative stage but is disrupted by excessive motion at the fracture site
Description : In a patient of pulmonary tuberculosis, pyrazinamide is most active on the following subpopulation of tubercle bacilli: A. Rapidly multiplying bacilli located on cavity walls B. Slow ... showing inflammatory response C. Intermittently multiplying bacilli within caseous material D. Dormant bacilli
Last Answer : B. Slow growing bacilli within macrophages and at sites showing inflammatory response
Description : The AIDS viruses specifically attack which kind of cell? a) B cells b) helper T cells c) killer T cells d) macrophages
Last Answer : ANSWER: B -- HELPER T CELLS
Description : In our body, antibodies are formed against pathogens in (1) liver by RBC (2) blood by platelets (3) brain by macrophages (4) thymus by lymphocytes
Last Answer : thymus by lymphocytes