Description : Insulin release from pancreatic β cells is augmented by the following except: A. Ketone bodies B. Glucagon C. Vagal stimulation D. Alfa adrenergic agonists
Last Answer : D. Alfa adrenergic agonist
Description : Adrenaline raises blood glucose level by the following actions except: A. Inducing hepatic glycogenolysis B. Inhibiting insulin secretion from pancreatic β cells C. Augmenting glucagon secretion from pancreatic α cells D. Inhibiting peripheral glucose utilization
Last Answer : D. Inhibiting peripheral glucose utilization
Description : Select the drug which tends to reverse insulin resistance by increasing cellular glucose transporters: A. Glibenclamide B. Rosiglitazone C. Acarbose D. Prednisolone
Last Answer : B. Rosiglitazone
Description : ___________ drug can cause lactic acidosis. a) Metformin b) Pioglitazone c) Repaglinide d) Glibenclamide
Last Answer : a) Metformin
Description : Metformin acts by: A. Releasing insulin from pancreas B. Suppressing gluconeogenesis and glucose output from liver
Last Answer : B. Suppressing gluconeogenesis and glucose output from liver
Description : β-cells of islet of langerhans of the pancreas secrete (A) Insulin (B) Glucagon (C) Somatostatin (D) Pancreatic polypeptide
Last Answer : Answer : A
Description : Choose the correct statement about nateglinide: A. It is a long acting oral hypoglycaemic drug B. Taken just before a meal, it limits postprandial hyperglycaemia in type 2 diabetes mellitus C. It lowers ... 1 and type 2 diabetes mellitus D. It acts by opening K+ channels in myocytes and adipocytes
Last Answer : B. Taken just before a meal, it limits postprandial hyperglycaemia in type 2 diabetes mellitus
Description : Choose the most suitable antihypertensive drug for a 45-year-old male company executive who has a travelling job. His blood pressure is 160/100 mm Hg, and he is a diabetic ... → rebound hypertension. Hydrochlorothiazide: May worsen diabetes; more likely to produce weakness, fatigue and impotenc
Last Answer : B. Enalapril
Description : Which of the following drugs is a potassium channel opener: A. Nicorandil B. Hydralazine C. Glibenclamide D. Amiloride
Last Answer : D. Amiloride
Description : Select the drug for which the following instructions must be given to the patient "To be taken on empty stomach in the morning with a full glass of water (not milk, tea or coffee), to remain ... not take any food or medicine for 30 min": A. Alfacalcidol B. Alendronate C. Glibenclamide D. Raloxifene
Last Answer : B. Alendronate
Description : he following antidiabetic drug inhibits intestinal brush border α-glucosidase enzymes: A. Acarbose B. Pioglitazone C. Metformin D. Guargum
Last Answer : A. Acarbose
Description : Metformin causes little lowering of blood sugar level in: A. Nondiabetics B. Obese diabetics C. Type 2 diabetics D. Diabetics not responding to sulfonylureas
Last Answer : A. Nondiabetics
Description : Metformin is preferred over phenformin because: A. It is more potent B. It is less liable to cause lactic acidosis C. It does not interfere with vitamin B12 absorption D. It is not contraindicated in patients with kidney disease
Last Answer : B. It is less liable to cause lactic acidosis
Description : Long-term thiazide therapy can cause hyperglycaemia by: A. Reducing insulin release B. Interfering with glucose utilization in tissues C. Increasing sympathetic activity D. Increasing corticosteroid secretion
Last Answer : A. Reducing insulin release
Description : Diazoxide is an effective hypotensive, but is not used in the long-term treatment of hypertension because: A. It impairs glucose tolerance by inhibiting insulin release B. It inhibits uric acid ... causes marked Na+ and water retention leading to development of tolerance D. All of the above
Last Answer : D. All of the above
Description : he following is true of nifedipine except: A. It can aggravate urine voiding difficulty in elderly males with prostatic hypertrophy B. It promotes Na+ retention by a renal tubular action to ... release from pancreas D. At high doses it can paradoxically increase the frequency of angina pectori
Last Answer : B. It promotes Na+ retention by a renal tubular action to cause ankle oedema as side effect
Description : Glucagon release from pancreas is stimulated by: A. High blood glucose level B. Insulin C. Somatostatin D. Adrenaline
Last Answer : D. Adrenaline
Description : Which of the following is not a sulfonylurea but acts by analogous mechanism to bring about quick and brief insulin release that is useful for normalizing meal time glycaemic excursions in type 2 diabetes mellitus: A. Glimepiride B. Miglitol C. Repaglinide D. Rosiglitazone
Last Answer : C. Repaglinide
Description : 16.6 Somatostatin inhibits the release of: A. Growth hormone B. Insulin C. Thyrotropin D. All of the above
Description : The following fluoroquinolones have augmented activity against gram positive bacteria except: A. Lomefloxacin B. Levofloxacin C. Gatifloxacin D. Moxifloxacin
Last Answer : A. Lomefloxacin
Description : Insulin in secreted by pancreatic cells-
Last Answer : Insulin in secreted by pancreatic cells- A. `alpha-`cells B. `beta-`cells C. Delta cells D. Gamma cells
Description : The α-cells of pancreas islets produce (A) Insulin (B) Glucagon (C) Somatostatin (D) Pancreatic polypeptide
Last Answer : Answer : B
Description : Adrenaline raises blood glucose level by the following actions except (a) Inducing hepatic glycogenolysis (b) Inhibiting insulin secretion from pancreatic ß cells (c) Augmenting glucagons secretion from pancreatic a cells (d) Inhibiting peripheral glucose utilization
Last Answer : Ans: D
Description : Select the correct statement. (a) Glucocorticoids stimulate gluconeogenesis. (b) Glucagon is associated with hypoglycemia. (c) Insulin acts on pancreatic cells and adipocytes. (d) Insulin is associated with hyperglycemia
Last Answer : (a) Glucocorticoids stimulate gluconeogenesis.
Description : β-cells of pancreas Produce (a) Insulin (b) Glucagon (c) Both (d) None
Last Answer : (a) Insulin
Description : Glucose entry into the cells of the following organ/ tissue is highly dependent on the presence of insulin: A. Brain B. Liver C. Adipose tissue D. Kidney tubules
Last Answer : C. Adipose tissue
Description : Action of Insulin does not include the following: A. Facilitation of glucose transport into cells B. Facilitation of glycogen synthesis by liver C. Facilitation of neoglucogenesis by liver D. Inhibition of lipolysis in adipose tissue
Last Answer : . Facilitation of neoglucogenesis by liver
Description : The drug that can directly release histamine from mast cells without involving antigen-antibody reaction is: A. Aspirin B. Procaine C. Morphine D. Sulfadiazine
Last Answer : C. Morphine
Description : This pancreatic hormone promotes hypogenesis: (A) Insulin (B) Glucagon (C) Stomato station (D) Pancreozymine
Description : This pancreatic hormone increases the blood-sugar level: (A) Insulin (B) Glucagon (C) Pancreozymin (D) Pancreatic polypeptide
Description : Which hormones do stimulate the production of pancreatic juice and bicarbonate? (a) Angiotensin and epinephrine (b) Gastrin and insulin (c) Cholecystokinin and secretin (d) Insulin and glucagon
Last Answer : (c) Cholecystokinin and secretin
Description : The β-lactam antibiotic(s) that prolong(s) bleeding time by altering surface receptors on platelets is/are: A. Carbenicillin B. Piperacillin C. Cefotaxime D. Both `A’ and `B’ are correct
Last Answer : A. Carbenicillin
Description : In patients of congestive heart failure, β-adrenergic blockers: A. Are absolutely contraindicated B. Can prolong survival C. Can improve haemodynamics after compensation has been restored D. Both B and C are correct
Last Answer : D. Both B and C are correct
Description : Adrenergic neurone blocking drugs: A. Block the action of adrenaline on neuronal α2 adrenoceptors B. Block both α and β adrenoceptor mediated effects of injected adrenaline C. Do not block any effect of injected adrenaline D. Do not block the effects of sympathetic nerve
Last Answer : C. Do not block any effect of injected adrenaline
Description : In patients of congestive heart failure, β -adrenergic blockers: A. Are absolutely contraindicated B. Can prolong survival C. Can improve haemodynamics after compensation has been restored D. Both B and C are correct
Description : Adrenergic neurone blocking drugs: A. Block the action of adrenaline on neuronal α2 adrenoceptors B. Block both α and β adrenoceptor mediated effects of injected adrenaline C. Do not block any effect of injected adrenaline D. Do not block the effects of sympathetic nerve stimulation
Description : Which of the following statement(s) is/are true concerning the neuroendocrine responses to shock? a. Sympathetic nerve endings release epinephrine which is responsible for greater than 80% ... injury and sepsis d. The renin-angiotensin axis further augments the sympathetic-mediated vasoconstriction
Last Answer : Answer: c, d The neuroendocrine response to shock attempts to achieve restoration of effective blood volume, mobilization of metabolic substrates, and maintenance of central ... . Angiotensin II is an extremely effective vasoconstrictor that further augments sympathetic-mediated vasoconstriction
Description : Release of pancreatic juice is stimulated by (a) enterokinase (b) cholecystokinin (c) trypsinogen (d) secretin
Last Answer : d) secretin.
Description : Glucocorticoids impair carbohydrate tolerance by: A. Promoting gluconeogenesis in liver B. Depressing glucose uptake into skeletal muscles C. Inhibiting insulin secretion D. Both A and B are correct
Last Answer : D. Both A and B are correct
Description : Sulfonylurea hypoglycaemics act by: A. Reducing intestinal absorption of glucose B. Increasing insulin secretion from pancreas C. Reversing down-regulation of insulin receptors D. Both ‘B’ and ‘C’ are correct
Last Answer : D. Both ‘B’ and ‘C’ are correct
Description : In diabetic patients, round the clock tight control of hyperglycaemia achieved by multiple daily insulin injections or insulin pumps: A. Prevents macrovascular disease more effectively B. Is recommended ... Is associated with higher incidence of hypoglycaemic reactions D. Both A and C are correct
Last Answer : D. Both A and C are correct
Description : Which of the following drugs is a potassium channel opener ? (a) Pinacidil (b) Hydralazine (c) Glibenclamide (d) Amiloride
Last Answer : Ans: A
Description : The following is true of mefloquine: A. P. falciparum does not develop resistance to mefloquine B. Concurrent use of β blockers with mefloquine is contraindicated C. Neuropsychiatric reactions are the most important adverse effects of mefloquine D. All of the above
Last Answer : C. Neuropsychiatric reactions are the most important adverse effects of mefloquine
Description : Choose the drug whose single oral dose affords clinical cure of uncomplicated malaria caused by chloroquine sensitive/resistant P.falciparum as well as P. vivax: A. Quinine B. Mefloquine C. Artesunate D. Proguanil
Last Answer : B. Mefloquine
Description : The following antibiotic(s) exert(s) a long postantibiotic effect: A. Fluoroquinolones B. β-lactams C. Aminoglycosides D. All of the above
Description : The following statements are true about imipenem except: A. It is a β-lactam antibiotic, but neither a penicillin nor a cephalosporin B. It is rapidly degraded in the kidney C. It is safe in epileptics D. It is always given in combination with cilastatin
Last Answer : C. It is safe in epileptics
Description : What is true of cefpirome: A. It is a fourth generation cephalosporin B. It easily penetrates porin channels of gram negative bacteria C. It inhibits type I β-lactamase producing enterobacteriaceae D. All of the above
Last Answer : . All of the above
Description : Which of the following is a second generation cephalosporin that is highly resistant to gram negative β-lactamases, and cures penicillinase positive as well as negative gonococcal infection by a single intramuscular dose: A. Cephalexin B. Cefuroxime C. Cefoperazone D. Ceftazidime
Last Answer : B. Cefuroxime