Pentazocine differs from morphine in that:
A. It is inactive by the oral route
B. It does not produce physical dependence
C. It has a lower ceiling of analgesic effect
D. Its action is not blocked by naloxone

1 Answer

Answer :

C. It has a lower ceiling of analgesic effec

Related questions

Description : Pentazocine differs from morphine in that (a) It is inactive by the oral route (b) It does not produce physical dependence (c) It has a lower ceiling of analgesic effect (d) Its action is not blocked by naloxone

Last Answer : Ans: C

Description : Lower dose of naloxone is required to: A. Antagonise the actions of nalorphine B. Antagonise the actions of pentazocine C. Precipitate withdrawal in mildly morphine dependent subjects D. Precipitate withdrawal in highly morphine dependent subjects

Last Answer : D. Precipitate withdrawal in highly morphine dependent subjects

Description : Indicate the opioid analgesic that is used as transdermal patch for chronic and cancer pain: A. Morphine B. Pentazocine C. Fentanyl D. Tramadol

Last Answer : The distinctive feature(s) of methadone compared to morphine is/are: A. High oral bioavailability B. High plasma protein and tissue binding C. Delayed and milder withdrawal symptoms in dependent subjects D. All of the above

Description : Lower dose of naloxone is required to (a) Antagonise the actions of nalorphine (b) Antagonise the actions of pentazocine (c) Precipitate withdrawal in mildly morphine dependent subjects (d) Precipitate withdrawal in highly morphine dependent subjects

Last Answer : Ans: D

Description : The following is true of buprenorphine: A. It is an agonist-antagonist type of opioid analgesic B. Its subjective effects are different from those of morphine C. Naloxone is largely ineffective in reversing its effects D. It produces mydriasis

Last Answer : C. Naloxone is largely ineffective in reversing its effects

Description : Ganglion blocking drugs are no longer used in therapeutics because: A. They have few and weak pharmacological actions B. They produce many side effects C. They are inactive by oral route D. They have short duration of action

Last Answer : A. They have potent antiovulatory action of their own

Description : Ganglion blocking drugs are no longer used in therapeutics because: A. They have few and weak pharmacological actions B. They produce many side effects C. They are inactive by oral route D. They have short duration of action

Last Answer : B. They produce many side effects

Description : Choose the correct statement about codeine: A. It has a lower oral: parenteral activity ratio than morphine B. It is devoid of abuse liability C. It is a weaker analgesic than morphine D. It is a more potent antitussive than morphine

Last Answer : C. It is a weaker analgesic than morphine

Description : Fluconazole differs from ketoconazole in that: A. It is not active by the oral route B. It is a more potent inhibitor of drug metabolism C. It is not effective in cryptococcal meningitis D. It is unlikely to produce anti-androgenic side effects

Last Answer : D. It is unlikely to produce anti-androgenic side effects

Description : The following is not true of morphine: A. Its 2-glucuronide metabolite is an active analgesic B. Its active metabolite penetrates blood-brain barrier better than morphine C. Its oral: parenteral activity ratio is 1:4 D. It undergoes enterohepatic cycling

Last Answer : B. Its active metabolite penetrates blood-brain barrier better than morphine

Description : Which action of morphine is incompletely reversed by naloxone: A. Analgesia B. Respiratory depression C. Sedation D. Miosis

Last Answer : C. Sedation

Description : Morphine analgesia differs from that produced by aspirin in the following respect(s): A. It has a higher ceiling B. It covers both perception as well as psychic processing of the pain C. Visceral and ischaemic pain is relieved better than somatic inflammatory pain D. All of the above are correct

Last Answer : D. All of the above are correct

Description : Select the opioid analgesic which acts primarily through κ (kappa) opioid receptor: A. Pentazocine B. Methadone C. Buprenorphine D. Pethidine

Last Answer : A. Pentazocine

Description : Which of the following is an agonist-antagonist type of opioid analgesic: A. Pethidine B. Pentazocine C. Fentanyl D. Buprenorphine

Last Answer : B. Pentazocine

Description : Morphine dependence is characterized by: A. Marked drug seeking behaviour B. Physical dependence without psychic dependence C. Physical as well as psychic dependence D. Both ‘A’ and ‘C’ are correc

Last Answer : D. Both ‘A’ and ‘C’ are correc

Description : Choose the correct statement about pentazocine: A. It causes bradycardia and fall in blood pressure B. Its subjective effects are pleasurable at low doses but turn unpleasant at high doses C. It induces vomiting frequently D. It substitutes for morphine in dependent subjects

Last Answer : B. Its subjective effects are pleasurable at low doses but turn unpleasant at high doses

Description : Nalorphine is nearly equipotent analgesic as morphine, but is not used clinically as an analgesic because: A. It causes more marked respiratory depression B. It has higher abuse potential C. It antagonises the action of morphine D. It produces prominent dysphoric effects

Last Answer : D. It produces prominent dysphoric effects

Description : The antidote of choice for morphine poisoning is: A. Nalorphine B. Nalbuphine C. Naltrexone D. Naloxone

Last Answer : D. Naloxone

Description : Methyldopa differs from clonidine in the following respect: A. It is less likely to cause rebound hypertension on sudden discontinuation B. It does not reduce plasma renin activity C. It has a central as well as peripheral site of antihypertensive action D. It does not produce central side effect

Last Answer : A. It is less likely to cause rebound hypertension on sudden discontinuation

Description : Enalapril differs from captopril in that: A. It blocks angiotensin II receptors B. It does not produce cough as a side effect C. It is less liable to cause abrupt first dose hypotension D. It has a shorter duration of action

Last Answer : C. It is less liable to cause abrupt first dose hypotension

Description : In the treatment of parkinsonism, bromocriptine differs from levodopa in the following respects except: A. It does not need conversion to an active metabolite B. It has a longer duration of ... with little/antagonistic action on D1 receptors D. It does not produce behavioral/psychiatric side effect

Last Answer : D. It does not produce behavioral/psychiatric side effects

Description : Enalapril differs from captopril in the following features except: A. It is dose to dose more potent B. Its oral absorption is not affected by food in stomach C. It acts more rapidly D. It has longer duration of action

Last Answer : D. Lisinopri

Description : The antiparkinsonian action of central anticholinergics has the following features except: A. They control tremor more than rigidity B. They produce a low ceiling therapeutic effect C. They are effective in neuroleptic drug induced parkinsonism D. They are the preferred drugs in advanced case

Last Answer : D. They are the preferred drugs in advanced cases

Description : Which action of morphine is incompletely reversed by naloxone ? (a) Analgesia (b) Respiratory depression (c) Sedation (d) Miosis

Last Answer : Ans: C

Description : Regular low-to-moderate alcohol consumption is associated with: A. Lower incidence of coronary artery disease B. Myocardial depression C. Physical dependence D. Wernicke's encephalopathy

Last Answer : A. Lower incidence of coronary artery disease

Description : The β3 adrenoceptor differs from the other subtypes of β receptor in that it: A. Is not blocked by the conventional doses of propranolol B. Is located primarily in the heart C. Regulates blood sugar level D. Is not coupled to G proteins

Last Answer : A. Is not blocked by the conventional doses of propranolol

Description : The β 3 adrenoceptor differs from the other subtypes of β receptor in that it: A. Is not blocked by the conventional doses of propranolol B. Is located primarily in the heart C. Regulates blood sugar level D. Is not coupled to G proteins

Last Answer : A. Is not blocked by the conventional doses of propranolol

Description : Sustained/controlled release oral dosage form is appropriate for the following type of drug: A. An antiarthritic with a plasma half life of 24 hr B. A sleep inducing hypnotic with a plasma half life of ... 3 hours D. An analgesic with a plasma half life of 6 hours used for relief of casual headache

Last Answer : C. An antihypertensive with a plasma half life of 3 hours

Description : Select the correct statement about Naloxone: A. It equally blocks μ, κ and δ opioid receptors B. It blocks μ receptors at lower doses than those needed for others C. It blocks κ receptors at lower doses than those needed for others D. It blocks δ receptors at lower doses than those needed for others

Last Answer : B. It blocks μ receptors at lower doses than those needed for others

Description : What is TRUE about Benzodiazepine and diazepam in 5-10mg oral dose used for oral sedation in dentistry: A. Good analgesic effect if given 1 hour prior to dental sessions B. Would be reversed ... Benzodiazepam C. Post operative headache D. There is a profound amnesic action and no side affects

Last Answer : B. Would be reversed by flumazepil because it is a Benzodiazepam

Description : Which of the following is an agonistantagonist type of opioid analgesic (a) Pethidine (b) Pentazocine (c) Fentanyl (d) Buprenorphine

Last Answer : Ans: B

Description : The distinctive feature(s) of methadone compared to morphine is/are: A. High oral bioavailability B. High plasma protein and tissue binding C. Delayed and milder withdrawal symptoms in dependent subjects D. All of the above

Last Answer : D. All of the above

Description : Morphine dependence is characterized by (a) Marked drug seeking behavior (b) Physical dependence without psychic dependence (c) Physical as well as psychic dependence (d) Both (a) and (c)

Last Answer : Ans: D

Description : Ranitidine differs from cimetidine in the following respect: A. It is less potent B. It is shorter acting C. It does not have antiandrogenic action D. It produces more CNS side effect

Last Answer : C. It does not have antiandrogenic action

Description : Tinidazole differs from metronidazole in that: A. It is not active against anaerobic bacteria B. It has a broader spectrum of activity C. It has a longer elimination half life D. It has better oral absorption

Last Answer : C. It has a longer elimination half life

Description : Transdermal estradiol differs from oral estrogen therapy in that it: A. Causes less induction of hepatic synthesis of clotting factors B. Does not inhibit FSH secretion C. Does not affect vaginal cytology D. All of the above are correct

Last Answer : A. Causes less induction of hepatic synthesis of clotting factors

Description : The progestin used in combined oral contraceptive pill is a 19-nortestosterone derivative because: A. They have potent antiovulatory action of their own B. They do not produce any metabolic effects C. They produce fewer side effects D. They are longer acting

Last Answer : A. They have potent antiovulatory action of their own

Description : All the following statements about βendorphin are true except µ : (A) It is a polypeptide (B) Its precursor is pro-opio-melanocortin (C) Its receptors are represent in brain (D) Its action is blocked by morphine

Last Answer : Answer : D

Description : Patient with morphine coma; what is the medication of choice to reverse its act: a. Bradykinin. b. Epinephrine. c. Amphetamine. d. Naloxone.

Last Answer : d. Naloxone.

Description : In patients with morphine coma, what is the medication of choice to reverse its act: A. Bradykinin B. Epinephrine C. Amphetamine D. Naloxone

Last Answer : D. Naloxone

Description : When therapeutic effects decline both below and above a narrow range of doses, a drug is said to exhibit: A. Ceiling effect B. Desensitization C. Therapeutic window phenomenon D. Nonreceptor mediated action

Last Answer : C. Therapeutic window phenomenon

Description : The following is correct about antipsychotic drugs except: A. They only control symptoms of schizophrenia without affecting the basic disorder B. Combination of two or more antipsychotic drugs is ... psychosis high potency drugs are preferred over low potency drugs D. They donot produce dependence

Last Answer : B. Combination of two or more antipsychotic drugs is more efficacious than any single drug

Description : The following drug is not likely to produce dependence: A. Diazepam B. Chlorpromazine C. Pethidine D. Methadone

Last Answer : B. Chlorpromazine

Description : Select the antifungal drug which is administered only by the oral route: A. Amphotericin B B. Ketoconazole C. Griseofulvin D. Tolnaftate

Last Answer : C. Griseofulvin

Description : Teicoplanin has the following feature(s): A. Antimicrobial activity and indications similar to vancomycin B. Long elimination half-life C. Efficacy in systemic infections by oral route D. Both ‘A’ and ‘B’ are correct

Last Answer : D. Both ‘A’ and ‘B’ are correct

Description : Choose the correct statement(s) about cefepime: A. It is a 4th generation cephalosporin B. It is active against many bacteria resistant to 3rd generation celphalosporins C. It is active by the oral route D. Both 'A' and 'B' are correct

Last Answer : D. Both 'A' and 'B' are correct

Description : Choose the correct statement about ondansetron: A. It is a dopamine D2 receptor antagonist B. It suppresses postoperative nausea and vomiting C. It is the most effective antiemetic for motion sickness D. It is not effective by oral route

Last Answer : B. It suppresses postoperative nausea and vomitin

Description : A patient of acute myocardial infarction being treated in intensive care unit developed left ventricular failure with raised central venous pressure. It was decided to use glyceryl trinitrate. Which route ... suitable: A. Sublingual B. Oral C. Intravenous bolus injection D. Slow intravenous infusion

Last Answer : D. Slow intravenous infusion

Description : For the treatment of hypogonadism and impotence, testosterone/dihydrotestosterone can be administered by the following route/routes: A. Oral B. Intramuscular C. Transdermal D. Both 'B' and 'C

Last Answer : D. Both 'B' and 'C'

Description : The following statement is correct about buspirone: A. It interacts with benzodiazepine receptor as an inverse agonist B. It is a rapidly acting anxiolytic, good for panic states C. ... suppresses barbiturate withdrawal syndrome D. It has anxiolytic but no anticonvulsant or muscle relaxant propert

Last Answer : D. It has anxiolytic but no anticonvulsant or muscle relaxant property