Description : The following local anaesthetic is poorly water soluble, PABA derivative and primarily used for anorectal lesions, wounds and ulcers: A. Benzocaine B. Dibucaine C. Procaine D. Benoxinate
Last Answer : A. Benzocaine
Description : Which of the following statements is true for lignocaine: A. It is an ester-linked local anaesthetic B. It is not likely to exhibit cross-sensitivity with procaine C. It has a shorter duration of action than procaine D. It is not a surface anaesthetic
Last Answer : B. It is not likely to exhibit cross-sensitivity with procaine
Description : The local anaesthetic having high cardiotoxic and arrhythmogenic potential is: A. Lignocaine B. Procaine C. Bupivacaine D. Ropivacaine
Last Answer : C. Bupivacaine
Description : Which of the following is a poor surface anaesthetic: A. Procaine B. Lignocaine C. Tetracaine D. Benoxinate
Last Answer : A. Procaine
Description : Histamine is involved as a mediator in the following pathological conditon (a) Cocaine (b) Dibucaine (c) Lidocaine (d) Procaine
Last Answer : Ans: B
Description : Bradykinin and angiotensin II have the following feature common to both: A. They both cause fall in BP B. They both are degraded by Kininase II C. Their precursor proteins are plasma α2 globulins D. They both release aldosterone from adrenal cortex
Last Answer : C. Their precursor proteins are plasma α2 globulins
Description : Advantages of selective serotonin reuptake inhibitors (SSRIs) include the following except: A. No interference with ejaculation and orgasm B. Minimal sedative action C. Unlikely to cause fall in BP D. Lack of seizure precipitating potential
Last Answer : A. No interference with ejaculation and orgasm
Description : The following is true of procainamide except: A. It generates an active metabolite in the body B. Its plasma half-life is longer than that of quinidine C. On long-term use, it ... erythematosus like illness D. It is effective in many cases of ventricular extrasystoles, not responding to lignocaine
Last Answer : A. Disopyramide
Description : Epidural anaesthesia differs from spinal anaesthesia in that: A. Epidural anaesthesia produces less cardiovascular complications B. Headache is more common after epidural anaesthesia C. Blood ... . Greater separation between sensory and motor blockade can be obtained with epidural anaesthes
Last Answer : D. Greater separation between sensory and motor blockade can be obtained with epidural anaesthesia
Description : The duration of spinal anaesthesia depends on each of the following except: A. Which local anaesthetic is used B. Concentration of the local anaesthetic used C. Posture of the patient D. Whether adrenaline has been added to the local anaesthetic
Last Answer : C. Posture of the patient
Description : The segmental level of spinal anaesthesia depends on: A. Volume of the local anaesthetic injected B. Specific gravity of the local anaesthetic solution C. Posture of the patient D. All of the above factors
Last Answer : D. All of the above factors
Description : n which of the following techniques the concentration of the local anaesthetic used is the lowest: A. Infiltration anaesthesia B. Nerve block anaesthesia C. Spinal anaesthesia D. Epidural anaesthesia
Last Answer : A. Infiltration anaesthesia
Description : Choose the local anaesthetic that is specifically used to produce corneal anaesthesia for tonometry: A. Tetracaine B. Oxethazaine C. Ropivacaine D. Benoxinate
Last Answer : D. Benoxinate
Description : Adrenaline added to local anaesthetic solution for infiltration anaesthesia affords the following except: A. Prolongs the duration of local anaesthesia B. Makes the injection less painful C. Provides a more bloodless field for surgery D. Reduces systemic toxicity of the local anaesthetic
Last Answer : B. Makes the injection less painful
Description : Injection of adrenaline along with a local anaesthetic serves the following purpose: A. Lowers the concentration of the local anaesthetic to produce nerve block B. Prolongs the duration of local anaesthesia C. Increases the anaesthetised area D. Reduces the local toxicity of the local anaesthetic
Last Answer : B. Prolongs the duration of local anaesthesia
Description : Which sensation is blocked first by low concentrations of a local anaesthetic: A. Pain B. Temperature C. Touch D. Deep pressure
Last Answer : A. Pain
Description : The following is not true of local anaesthetics: A. The local anaesthetic is required in the unionized form for penetrating the neuronal membrane B. The local anaesthetic approaches its receptor ... the resting state D. The local anaesthetic combines with its receptor in the ionized cationic form
Last Answer : C. The local anaesthetic binds to its receptor mainly when the Na+ channel is in the resting state
Description : The local anaesthetics having amide linkage differ from those having ester linkage in that the amidelinked local anaesthetics: A. Are not surface anaesthetics B. Have a shorter duration of action C. Are degraded in the plasma D. Do not show cross-sensitivity with esterlinked local anaesthetic
Last Answer : D. Do not show cross-sensitivity with esterlinked local anaesth
Description : Use of sublingual/oral nifedipine soft geletine capsule for rapid BP lowering in hypertensive urgency has been discarded because of: A. Delayed onset of action B. Inability to control the rate and extent of fall in BP C. Reports of adverse/fatal outcome D. Both 'B' and 'C'
Last Answer : D. Both 'B' and 'C'
Description : Actions of adenosine include the following except: A. Depression of A-V node B. Coronary vasodilatation C. Bronchodilatation D. Fall in BP
Last Answer : C. Bronchodilatation
Description : Select the nonapeptide which can be generated from plasma globulin by snake venom enzymes, causes fall in BP and intense pain when applied to blister base: A. Kallidin B. Bradykinin C. Angiotensin II D. Angiotensin III
Last Answer : B. Bradykinin
Description : Potentiation of bradykinin appears to play a role in the following effects of angiotensin converting enzyme inhibitors except: A. Fall in BP in the short term B. Fall in BP in the long term C. Cough in susceptible individuals D. Angioedema in susceptible individuals
Last Answer : B. Fall in BP in the long term
Description : Phentolamine test is considered positive for pheochromocytoma if there is a: A. Rise in BP by more than 35 mm Hg systolic and 25 mm Hg diastolic B. Rise in systolic but fall in diastolic BP C. Fall in both ... 20 mm Hg D. Fall in BP by more than 35 mm Hg systolic and more than 25 mm Hg diastolic
Last Answer : D. Fall in BP by more than 35 mm Hg systolic and more than 25 mm Hg diastolic
Description : The typical response to intravenous injection of 5-HT in an anaesthetised animal is: A. Rise in BP B. Fall in BP C. Rise followed by brief fall in BP D. Transient fall, followed by brief rise, followed by prolonged fall in BP
Last Answer : D. Transient fall, followed by brief rise, followed by prolonged fall in BP
Description : Which local anesthetic should be used to treat symptoms of pain, itching, burning, and disconfort in patients with an established lidocaine allergy? (a) Tetracaine (b) Dibucaine (c) Pramoxine (d) Benzocaine
Last Answer : Ans: C
Description : Which of the following is not a semisynthetic penicillin: A. Procaine penicillin B. Ampicillin C. Cloxacillin D. Carbenicillin
Last Answer : A. Procaine penicillin
Description : The penicillin G preparation with the longest duration of action is: A. Benzathine penicillin B. Sodium penicillin C. Potassium penicillin D. Procaine penicillin
Last Answer : A. Benzathine penicillin
Description : The drug that can directly release histamine from mast cells without involving antigen-antibody reaction is: A. Aspirin B. Procaine C. Morphine D. Sulfadiazine
Last Answer : C. Morphine
Description : Pancuronium differs from tubocurarine in that: A. It is a depolarizing blocker B. Its action is not reversed by neostigmine C. It can cause rise in BP on rapid I.V. injection D. It causes marked histamine release
Last Answer : C. It can cause rise in BP on rapid I.V. injection
Description : Started within 4-6 hours of acute myocardial infarction, which of the following drug(s) can reduce the area of necrosis and the attendant mortality: A. Propranolol B. Glyceryl trinitrate C. Lignocaine D. Both ‘A’ and ‘B’ are correct
Last Answer : D. Both ‘A’ and ‘B’ are correct
Description : Which of the following drugs depresses automaticity of SA node as well as ectopic foci, abbreviates action potential duration of Purkinje fibres, and slows atrioventricular conduction: A. Propranolol B. Lignocaine C. Procainamide D. Bretylium
Last Answer : A. Propranolol
Description : Select the drug which is used by intravenous infusion for emergency control of tachycardia and sudden rise in blood pressure: A. Amiodarone B. Lignocaine C. Esmolol D. Disopyramide
Last Answer : C. Esmolo
Description : The following is an orally active lignocaine congener used for both acute as well as chronic ventricular arrhythmias: A. Mexiletine B. Flecainide C. Moricizine D. Propafenone
Last Answer : A. Mexiletine
Description : Lignocaine is the preferred antiarrhythmic for emergency control of cardiac arrhythmias following acute myocardial infarction because: A. It has a rapidly developing and titratable antiarrhythmic action B. It causes ... atrial as well as ventricular arrhythmias D. Both A' and B' are correct
Description : yocardial Na+ channel blockade by lignocaine has the following characteristic: A. It blocks inactivated Na+ channels more than activated channels B. It blocks activated Na+ channels more than inactivated ... Na+ channels D. It produces more prominent blockade of atrial than ventricular Na+ channels
Last Answer : A. It blocks inactivated Na+ channels more than activated channels
Description : The most significant feature of the antiarrhythmic action of lignocaine is: A. Suppression of phase-4 depolarization in ventricular ectopic foci B. Prolongation of action potential duration C. Prolongation of effective refractory period D. Depression of membrane responsiveness
Last Answer : A. Suppression of phase-4 depolarization in ventricular ectopic foci
Description : The following antiarrhythmic drug has the most prominent anticholinergic action: A. Disopyramide B. Quinidine C. Procainamide D. Lignocaine
Description : The antiarrhythmic drug which decreases both rate of depolarization (phase 0) as well as rate of repolarization (phase 3) of myocardial fibres is: A. Lignocaine B. Propranolol C. Quinidine D. Verapamil
Last Answer : C. Quinidine
Description : Select the most suitable antiarrhythmic drug for counteracting ventricular extrasystoles due to digoxin toxicity: A. Lignocaine B. Quinidine C. Verapamil D. Amiodarone
Last Answer : A. Lignocaine
Description : A resting nerve is relatively resistant to blockade by lignocaine compared to one which is repeatedly stimulated because: A. Lignocaine penetrates resting nerve membrane poorly B. Lignocaine binds ... promotes ionization of lignocaine D. Nodes of Ranvier are inaccessible in the resting state
Last Answer : B. Lignocaine binds more avidly to the inactivated Na+ chan
Description : Sensitivity of a nerve fibre to blockade by lignocaine depends on: A. Whether the fibre is sensory or motor B. Whether the fibre is myelinated or nonmyelinated C. Internodal distances in the fibre D. Both ‘B’ and ‘C’ are correct
Last Answer : D. Both ‘B’ and ‘C’ are correct
Description : Which of the following is the LEAST to cause toxicity from local anaesthetic injection: A. Injecting in supine position B. Injecting in vascular area C. Injecting without a vasoconstrictor D. Intravenous injections
Last Answer : A. Injecting in supine position
Description : he antiepileptic drug which suppresses maximal electroshock as well as kindled seizures, raises pentylenetetrazol threshold and is effective in both generalized tonic-clonic as well as absence seizures is: A. Phenytoin B. Carbamazepine C. Sodium valproate D. Ethosuximide
Last Answer : C. Sodium valproate
Description : The following antiepileptic drug raises pentylene tetrazol seizure threshold but does not modify maximal electroshock seizures: A. Ethosuximide B. Carbamazepine C. Primidone D. Phenobarbitone
Last Answer : A. Ethosuximide
Description : What is true of tamoxifen: A. It can induce endometrial proliferation in postmenopausal women B. It exerts antiestrogenic activity in bone C. It raises LDL-cholesterol levels D. It is ineffective in estrogen receptor-negative breast cancer
Last Answer : A. It can induce endometrial proliferation in postmenopausal women
Description : Which of the following is true of acarbose: A. It reduces absorption of glucose from intestines B. It produces hypoglycaemia in normal as well as diabetic subjects C. It limits postprandial hyperglycaemia in diabetics D. It raises circulating insulin levels
Last Answer : C. It limits postprandial hyperglycaemia in diabetics
Description : Adrenaline raises blood glucose level by the following actions except: A. Inducing hepatic glycogenolysis B. Inhibiting insulin secretion from pancreatic β cells C. Augmenting glucagon secretion from pancreatic α cells D. Inhibiting peripheral glucose utilization
Last Answer : D. Inhibiting peripheral glucose utilization