Description : The tetracycline with highest antileprotic activity is: A. Minocycline B. Doxycycline C. Demeclocycline D. Oxytetracycline
Last Answer : A. Minocycline
Description : Select the most potent tetracycline antibiotic: A. Demeclocycline B. Oxytetracycline C. Minocycline D. Doxycycline
Last Answer : C. Minocycline
Description : Select the most potent tetracycline antibiotic (a) Demeclocycline (b) Methacycline (c) Minocycline (d) Doxycycline
Last Answer : Ans: C
Description : he most suitable tetracycline for use in a patient with impaired renal function is: A. Tetracycline B. Demeclocycline C. Oxytetracycline D. Doxycycline
Last Answer : D. Doxycycline
Description : The most suitable tetracycline for use in a patient with impaired renal function is (a) Chlortetracycline (b) Demeclocycline (c) oxytetracycine (d) Doxycycline
Last Answer : Ans: D
Description : The characteristic toxicity of ethambutol is: A. Hepatitis B. Visual defects C. Vestibular disturbance D. Renal damage
Last Answer : B. Visual defects
Description : Compared to older tetracyclines, doxycycline produces a lower incidence of superinfection diarrhoea because: A. It is completely absorbed in the small intestines so that drug concentration in the colonic contents ... the microbes of the normal gut flora D. It is a potent tetracycline and inhibits
Last Answer : A. It is completely absorbed in the small intestines so that drug concentration in the colonic contents is low
Description : Compared to older tetracyclines, doxycycline produces a lower incidence of superinfection diarrhoea because (a) It is completely absorbed in the small intestines so that drug concentration in the colonic ... (d) It is a potent tetracycline and inhibits the superinfection causing microbes as well
Last Answer : Ans: A
Description : In which of the following groups do all four drugs warrant careful monitoring for drugrelated seizures in high-risk patients? (a) Penicillin G, imipenem, amphotericin B, metronidazol ... (d) Cycloserine, metronidazole, vancomycin, sulfadiazine (e) Metronidazole, imipenem, doxycycline, erythromycin
Description : A single dose rifampin + ofloxacin + minocycline treatment has been recommended for: A. All cases of paucibacillary leprosy B. All relapse cases of paucibacillary leprosy C. Single skin lesion paucibacillary leprosy D. None of the above
Last Answer : C. Single skin lesion paucibacillary leprosy
Description : Which antileprotic drug suppresses lepra reaction and reversal reaction as well: A. Dapsone B. Rifampin C. Clofazimine D. Minocycline
Last Answer : C. Clofazimine
Description : If a multibacillary leprosy patient treated with standard fixed duration multidrug therapy relapses, he should be treated with: A. The same rifampin + dapsone + clofazimine regimen B. ... + minocycline C. Clofazimine + ofloxacin + clarithromycin D. Ofloxacin + minocycline + clarithromycin
Last Answer : . The same rifampin + dapsone + clofazimine regimen
Description : The nonselective MAO inhibitors are not used clinically as antidepressants because of their: A. Low antidepressant efficacy B. Higher toxicity C. Potential to interact with many foods and drugs D. Both 'B' and 'C' are correct
Last Answer : D. Both 'B' and 'C' are correct
Description : The following drug of abuse is a hallucinogen: A. Cocaine B. Cannabis C. Heroin D. Methaqualone (p. 403) 31.1 Which of the following is a selective MAO-B inhibitor: A. Selegiline
Last Answer : B. Cannabis
Description : The following drug can cause rickets in children by interfering with vitamin D action: A. Tetracycline B. Digoxin C. Phenytoin D. Ciprofloxacin
Last Answer : C. Phenytoin
Description : Which aminoglycoside antibiotic causes more hearing loss than vestibular disturbance as toxic effect: A. Streptomycin B. Gentamicin C. Kanamycin D. Sisomicin
Last Answer : C. Kanamycin
Description : The following is true of vancomycin except: A. It is a bactericidal antibiotic active primarily against gram positive bacteria B. It acts by inhibiting bacterial protein synthesis C. It is an alternative to penicillin for enterococcal endocarditis D. It can cause deafness as a dose related toxicity
Last Answer : B. It acts by inhibiting bacterial protein synthesis
Description : The antipsychotic drug most likely to cause ocular toxicity on long-term use is: A. Thioridazine B. Haloperidol C. Flupenthixol D. Pimozide
Last Answer : A. Thioridazine
Description : The regimens recommended for treatment of chloroquine resistant P.falciparum malaria in an adult include the following except: A. Quinine 10 mg/kg/8 hourly+ doxycycline 100 mg/day for 7 days B. Quinine 10 mg/kg ... 7 days D. Artemether 80 mg i.m./twice on first day followed by once daily for 4 days
Last Answer : C. Mefloquine 0.5 g daily for 7 days
Description : An adult male living in nonmalarious area has to visit an area where chloroquine resistant P. falciparum is prevalent. He is intolerant to mefloquine and his G6PD status is unknown. Select the ... you will prescribe for prophylaxis of malaria: A. Primaquine B. Doxycycline C. Amodiaquine D. Quinine
Last Answer : B. Doxycycline
Description : The drug of choice for penicillinase producing Neisseria gonorrhoeae urethritis is: A. Amoxicillin B. Erythromycin C. Ceftriaxone D. Doxycycline
Last Answer : C. Ceftriaxone
Description : A single oral dose of the following antibiotic is curative in most patients of nonspecific urethritis due to Chlamydia trachomatis: A. Doxycycline B. Azithromycin C. Erythromycin D. Cotrimoxazole
Last Answer : B. Azithromycin
Description : Select the antibiotic(s) that can be used to treat nonspecific urethritis due to Chlamydia trachomatis: A. Azithromycin B. Doxycycline C. Clindamycin D. Both 'A' and 'B' are correct
Last Answer : D. Both 'A' and 'B' are correct
Description : The drug of choice for atypical pneumonia due to Mycoplasma pneumoniae is: A. Doxycycline B. Ciprofloxacin C. Ceftriaxone D. Gentamicin
Last Answer : A. Doxycycline
Description : A single oral dose of the following drug can cure most cases of uncomplicated gonorrhoea: A. Ciprofloxacin B. Cotrimoxazole C. Spectinomycin D. Doxycycline
Last Answer : A. Ciprofloxacin
Description : Select the antibiotic that has a high therapeutic index: A. Streptomycin B. Doxycycline C. Cephalexin D. Vancomycin
Last Answer : C. Cephalexin
Description : Tetracycline is indicated in the following form(s) of amoebic infection: A. Acute amoebic dysentery B. Chronic intestinal amoebiasis C. Amoebic liver abscess D. All of the above
Last Answer : B. Chronic intestinal amoebiasis
Description : The following drug is effective in hepatic amoebiasis but not in intestinal amoebiasis: A. Chloroquine B. Emetine C. Tetracycline D. Diloxanide furoate
Last Answer : A. Chloroquine
Description : Recrudescences attending 3 day artesunate therapy of chloroquine resistant falciparum malaria can be prevented by combining it with a single dose of: A. Quinine B. Primaquine C. Tetracycline D. Mefloquine
Last Answer : D. Mefloquine
Description : Indicate the drug that can be used as an alternative to primaquine for radical cure of vivax malaria: A. Atovaquone B. Bulaquine C. Tetracycline D. Proguanil
Last Answer : B. Bulaquine
Description : Select the antibiotic which inhibits bacterial protein synthesis by interfering with translocation of elongating peptide chain from acceptor site back to the peptidyl site of the ribosome so that ... chain is prematurely terminated: A. Chloramphenicol B. Erythromycin C. Tetracycline D. Streptomycin
Last Answer : B. Erythromycin
Description : Prolonged oral therapy with the following antibiotic can damage intestinal villi resulting in steatorrhoea and loose motions: A. Ampicillin B. Tetracycline C. Neomycin D. Nystatin
Last Answer : C. Neomycin
Description : The following antibiotic penetrates blood-CSF barrier the best: A. Erythromycin B. Gentamicin C. Tetracycline D. Chloramphenicol
Last Answer : D. Chloramphenicol
Description : A child presented with polyuria, weakness and fever. On the basis of investigations he was labelled to be suffering from Fancony syndrome. A history of taking some old left over antibiotic ... What could have been the antibiotic: A. Tetracycline B. Chloramphenicol C. Ampicillin D. Cephalexi
Last Answer : A. Tetracycline
Description : An 8-year-old child presented with brownish discoloured and deformed anterior teeth. History of having received an antibiotic about 4 years earlier was obtained. Which antibiotic could be responsible for the condition: A. Chloramphenicol B. Tetracycline C. Erythromycin D. Gentamicin
Last Answer : Tetracycline
Description : Bacteria develop tetracycline resistance by the following mechanisms except: A. Losing tetracycline concentrating mechanisms B. Elaborating tetracycline inactivating enzyme C. Synthesizing a protection protein' ... the target site D. Actively pumping out tetracycline that has entered the cell
Last Answer : B. Elaborating tetracycline inactivating enzym
Description : Which antimicrobial should be avoided in patients of liver disease: A. Tetracycline B. Cotrimoxazole C. Cephalexin D. Ethambutol
Description : 2 Which antibiotic is primarily bacteriostatic but becomes bactericidal at higher concentrations: A. Erythromycin B. Tetracycline C. Chloramphenicol D. Ampicillin
Last Answer : A. Erythromycin Although erythromycin is primarily bacteriostatic, it is bactericidal at high concentrations for some Gram-positive species, such as group A streptococci and pneumococci
Description : Which of the following adverse drug reactions is due to a specific genetic abnormality: A. Tetracycline induced sunburn like skin lesions B. Quinidine induced thrombocytopenia C. Metoclopramide induced muscle dystonia D. Primaquine induced massive haemolysis
Last Answer : D. Primaquine induced massive haemolysis
Description : Cyclosporine has the following attributes except: A. It selectively suppresses humoral immunity without affecting cell mediated immunity B. It is more active as immunosuppressant when administered before antigen exposure ... It is not toxic to the bone marrow D. Its major toxicity is kidney damage
Last Answer : A. It selectively suppresses humoral immunity without affecting cell mediated immunity
Description : The characteristic toxicity of doxorubicin is: A. Kidney damage B. Liver damage C. Cardiomyopathy D. Pulmonary fibrosis
Last Answer : C. Cardiomyopathy
Description : Methotrexate has the following attributes except: A. It is cell cycle specific and kills cells in the S phase B. Its toxicity primarily affects bone marrow and epithelial structures C. Folic acid reverses its toxic effects D. It is the drug of choice for choriocarcinoma
Last Answer : C. Folic acid reverses its toxic effects
Description : The most important toxicity of amphotericin B is: A. Nephrotoxicity B. Neurotoxicity C. Hepatotoxicity D. Bone marrow depression
Last Answer : A. Nephrotoxicity
Description : The most important dose dependent toxicity of dapsone is: A. Methemoglobinemia B. Haemolysis C. Hepatitis D. Dermatitis
Last Answer : B. Haemolysi
Description : Ethambutol is not used in children below 6 years of age because: A. Young children are intolerant to ethambutol B. Ethambutol causes growth retardation in young children C. It is ... induced visual impairment in young children D. In young children visual toxicity of ethambutol is irreversible
Last Answer : C. It is difficult to detect ethambutol induced visual impairment in young children
Description : A patient of bronchial asthma maintained on theophylline developed upper respiratory tract infection. Which antimicrobial if used can increase the risk of developing theophylline toxicity: A. Ampicillin B. Cephalexin C. Cotrimoxazole D. Erythromycin
Last Answer : D. Erythromycin
Description : Folinic acid is specifically indicated for: A. Prophylaxis of neural tube defect in the offspring of women receiving anticonvulsant medication B. Counteracting toxicity of high dose methotrexate C. Pernicious anaemia D. Anaemia associated with renal failure
Last Answer : C. Pernicious anaemia
Description : The following drug given concurrently can enhance toxicity of digoxin: A. Phenobarbitone B. Metoclopramide C. Quinidine D. Magnesium hydroxide
Last Answer : C. Quinidine
Description : Select the most suitable antiarrhythmic drug for counteracting ventricular extrasystoles due to digoxin toxicity: A. Lignocaine B. Quinidine C. Verapamil D. Amiodarone
Last Answer : A. Lignocaine
Description : Potassium therapy tends to counteract the cardiac toxicity of digitalis by: A. Reducing the affinity of sarcolemal Na+ K+ATPase for digitalis B. Suppressing ectopic automaticity enhanced by digitalis C. Promoting A-V conduction D. Both 'A' and 'B' are correct