Description : The following is true of clopidogrel except: A. It is a GPIIb/IIIa receptor antagonist B. It inhibits fibrinogen induced platelet aggregation C. It is indicated for prevention of stroke in patients with transient ischaemic attacks D. It is a prodrug
Last Answer : A. It is a GPIIb/IIIa receptor antagonist
Description : Choose the correct statement(s) about terlipressin: A. It is a prodrug B. It is used to control bleeding from esophageal varices C. It is preferred for controlling bleeding in von Willebrand's disease D. Both 'A' and 'B' are correct
Last Answer : D. Both 'A' and 'B' are correct
Description : Select the fastest acting inhaled bronchodilator: A. Ipratropium bromide B. Formoterol C. Salbutamol D. Salmeterol
Last Answer : C. Salbutamol
Description : The distinctive feature of terbinafine is: A. It is highly effective in histoplasmosis B. It can be used topically as well as orally for dermatophytosis C. It inhibits Mucor and Aspergillus as well D. Applied intravaginally it cures both candida as well as trichomonas vaginitis
Last Answer : B. It can be used topically as well as orally for dermatophytosis
Description : The following is true of linezolid except: A. It inhibits bacterial protein synthesis at an early step B. It is active against vancomycin resistant enterococci C. It is the drug of choice for enterococcal endocarditis D. It can be administered orally as well as by i.v. infusion
Last Answer : C. It is the drug of choice for enterococcal endocarditis
Description : To be a useful inhaled glucocorticoid the drug should have (a) High oral bioavailability (b) Low oral bioavailability (c) Additional bronchodilator activity (d) Prodrug character
Last Answer : Ans: B
Description : Choose the correct statement about famciclovir: A. It is active against acyclovir resistant strains of herpes simplex virus B. It does not need conversion to an active metabolite C. It is used orally to treat genital herpes simplex D. It is the drug of choice for cytomegalovirus retinitis
Last Answer : C. It is used orally to treat genital herpes simplex
Description : Choose the correct statement about lactulose: A. It stimulates myenteric neurones to enhance gut peristalsis B. Administered orally it acts as a purgative within 2-4 hours C. It is an osmotic laxative that produces soft but formed stools D. All of the above are correct
Last Answer : C. It is an osmotic laxative that produces soft but formed stools
Description : Choose the correct statement about iron therapy: A. Haemoglobin response to intramuscular iron is faster than with oral iron therapy B. Iron must be given orally except in pernicious anaemia C. ... iron therapy must be given during pregnancy D. Infants on breastfeeding do not require medicinal iron
Last Answer : C. Prophylactic iron therapy must be given during pregnancy
Description : Choose the correct statement(s) about auranofin: A. It is an orally active gold compound B. It is equally effective but less toxic than injected gold-sodium-thiomalate C. Its major adverse effect is dermatitis D. All of the above are correct
Last Answer : A. It is an orally active gold compound
Description : Choose the correct statement about nefopam: A. It is a nonopioid analgesic which does not inhibit prostaglandin synthesis B. It is an orally active opioid analgesic C. It is an analgesic with potent antiinflammatory activity D. It is a preferential COX-2 inhibitor
Last Answer : A. It is a nonopioid analgesic which does not inhibit prostaglandin synthesis
Description : Che following is true of desmopressin except: A. It is nonselective V1 and V2 receptor agonist B. It is more potent and longer acting than arginine vasopressin (AVP) C. It is preferred over AVP for treatment of diabetes insipidus D. It can be administered orally
Last Answer : A. It is nonselective V1 and V2 receptor agonist
Description : Choose the correct statement about ticlopidine: A. It blocks GPIIb/IIIa receptors on platelet membrane B. It prevents ADP mediated platelet adenylylcyclase inhibition C. It inhibits thromboxane A2 synthesis in platelets D. It does not prolong bleeding time
Last Answer : B. It prevents ADP mediated platelet adenylylcyclase inhibition
Description : Select the correct statement about salmeterol. (a) It is a long acting selective ß2 agonist bronchodilator (b) It is a bronchodilator with anti-inflammatory property (c) It is a ß blocker that can be safely given to asthmatics (d) It is an antihistaminic with mast cells stabilizing property
Last Answer : Ans: A
Description : Select the correct statement about salmeterol: A. It is a long acting selective β2 agonist bronchodilator B. It is a bronchodilator with anti-inflammatory property C. It is a β blocker that can be safely given to asthmatics D. It is an antihistaminic with mast cell stabilizing property
Last Answer : A. It is a long acting selective β2 agonist bronchodilator
Description : The following is an α2 adrenergic agonist used as eyedrops to lower intraocular pressure: A. Brinzolamide B. Bambuterol C. Brimonidine D. Latanoprost
Last Answer : C. Brimonidine
Description : The following is an α 2 adrenergic agonist used as eyedrops to lower intraocular pressure: A. Brinzolamide B. Bambuterol C. Brimonidine D. Latanoprost
Description : Succinylcholine produces spastic paralysis in: A. Rabbits B. Frogs C. Birds D. Patients with atypical pseudocholinesterase
Last Answer : C. Birds
Description : Choose the correct statement about long acting calcium channel blocking drugs as antihypertensives: A. They are the most effective drugs in suppressing hypertensive left ventricular hypertrophy B. They ... more than β blockers D. They have no beneficial effect in hypertensive/diabetic nephropath
Last Answer : B. They are as effective as diuretics or β blockers in reducing cardiovascular/total mortality
Description : Choose the correct statement about nateglinide: A. It is a long acting oral hypoglycaemic drug B. Taken just before a meal, it limits postprandial hyperglycaemia in type 2 diabetes mellitus C. It lowers ... 1 and type 2 diabetes mellitus D. It acts by opening K+ channels in myocytes and adipocytes
Last Answer : B. Taken just before a meal, it limits postprandial hyperglycaemia in type 2 diabetes mellitus
Description : Choose the correct statement about drotaverine: A. It is a smooth muscle antispasmodic acting by non-anticholinergic mechanisms B. It is a papaverine congener used in peripheral vascular diseases C. It ... used to control diarrhoea D. It is a M1/M3 selective antagonist used for spastic constipation
Last Answer : A. It is a smooth muscle antispasmodic acting by non-anticholinergic mechanisms
Description : Choose the drug that can be used orally for intestinal amoebiasis, intravaginally for trichomonas vaginitis and topically for dermatophytosis: A. Quiniodochlor B. Furazolidone C. Ornidazole D. Hamycin
Last Answer : A. Quiniodochlor
Description : Choose the orally active third generation cephalosporin having good activity against gram positive cocci as well: A. Cefdinir B. Ceftazidime C. Cefoperazone D. Ceftizoxime
Last Answer : A. Cefdinir
Description : Choose the ergot alkaloid that is well absorbed orally, has weak vascular but prominent uterine stimulant action: A. Ergometrine B. Ergotamine C. Dihydroergotamine D. Dihydroergotoxine
Last Answer : A. Ergometrine
Description : Trimethoprim inhibits bacteria without affecting mammalian cells because: A. It does not penetrate mammalian cells B. It has high affinity for bacterial but low affinity for mammalian dihydrofolate ... bacterial folate synthetase as well as dihydrofolate reductase enzymes D. All of the above
Last Answer : B. It has high affinity for bacterial but low affinity for mammalian dihydrofolate reductase enzyme
Description : Select the drug that reversibly inhibits the enzyme COMT and is useful as an adjuvant medication in advanced parkinson's disease: A. Pramipexole B. Entacapone C. Pergolide D. Piribedil
Last Answer : B. Entacapone
Description : The following is true of topiramate except: A. It is a broad spectrum antiepileptic drug B. It inhibits the enzyme carbonic anhydrase C. It is used as add-on therapy in refractory partial seizures D. It is not effective in generalized tonic-clonic seizures
Last Answer : D. It is not effective in generalized tonic-clonic seizures
Description : Hydrocortisone induces the synthesis of the following protein which in turn inhibits the enzyme phospholipase-A2: A. Heat shock protein-90 B. Inhibin C. Transcortin D. Lipocortin
Last Answer : D. Lipocortin
Description : Which of the following is a disease modifying antirheumatic drug whose active metabolite inhibits the enzyme dihydro-orotate dehydrogenase: A. Leflunomide B. Nimesulide C. Sulfasalazine D. Colchicine
Last Answer : A. Leflunomide
Description : The following is true of cyclophosphamide except: A. It is highly reactive and a vesicant on contact B. It is a prodrug C. It has marked immunosuppressant property D. It frequently causes alopecia and cystitis
Last Answer : A. It is highly reactive and a vesicant on contac
Description : The distinctive features of desogestrel include the following except: A. It is a prodrug B. It has both strong progestational and strong antiovulatory activities C. It has additional androgenic acitivity D. It does not counteract the beneficial effect of estrogen on lipid profile
Last Answer : C. It has additional androgenic acitivity
Description : he distinctive features of desogestrel include the following except: A. It is a prodrug B. It has both strong progestational and strong antiovulatory activities C. It has additional androgenic acitivity D. It does not counteract the beneficial effect of estrogen on lipid profile
Description : Which of the following is a prodrug of adrenaline used topically in glaucoma: A. Brimonidine B. Dipivefrine C. Phenylpropanolamine D. Dorzolamide
Last Answer : B. Dipivefrine
Description : 15.45 To be a useful inhaled glucocorticoid the drug should have: A. High oral bioavailability B. Low oral bioavailability C. Additional bronchodilator activity
Last Answer : B. Low oral bioavailability
Description : In an asthma patient treated with systemic corticosteroids, bronchodilator drugs: A. Are not needed B. Are contraindicated C. May be used on ‘as and when required’ basis D. Are ineffective
Last Answer : C. May be used on ‘as and when required’ basis
Description : Inhaled ipratropium bromide has the following advantages except: A. It does not alter respiratory secretions B. It does not depress airway mucociliary clearance C. It has faster onset of bronchodilator action than inhaled salbutamol D. It only rarely produces systemic side effects
Last Answer : C. It has faster onset of bronchodilator action than inhaled salbutamol
Description : Select the drug that is neither bronchodilator nor antiinflammatory, but has antihistaminic and mast cell stabilizing activity: A. Sodium cromoglycate B. Ketotifen C. Beclomethasone dipropionate D. Chlorpheniramine
Last Answer : B. Ketotifen
Description : The following antiasthma drug is not a bronchodilator: A. Ipratropium bromide B. Theophylline C. Formoterol D. Sodium cromoglycate
Last Answer : D. Sodium cromoglycate
Description : Choose the correct statement(s) about actions of insulin: A. It favours translocation of glucose transporters from intracellular site to the plasma membrane B. It enhances transcription of lipoprotein ... vascular endothelium C. It increases production of the enzyme glucokinase D. All of the above
Last Answer : D. All of the above
Description : Select the correct statement about ethamsylate: A. It checks capillary bleeding B. It inhibits platelet aggregation C. It is an antifibrinolytic drug D. It is used to fibrose bleeding piles
Last Answer : ut ethamsylate: A
Description : The following statement is true about ketoconazole except: A. It is less toxic than amphotericin B B. It produces a slower response than amphotericin B in systemic mycosis C. Given orally it is the first line treatment for vaginal candidiasis D. It is not effective in fungal meningitis
Last Answer : C. Given orally it is the first line treatment for vaginal candidiasis
Description : Choose the antiulcer drug that inhibits gastric acid secretion, stimulates gastric mucus and bicarbonate secretion and has cytoprotective action on gastric mucosa: A. Misoprostol B. Sucralfate C. Carbenoxolone sodium D. Colloidal bismuth subcitrate
Last Answer : A. Misoprostol
Description : Features of phenoxymethyl penicillin include the following: A. It is acid stable and orally active B. Its antibacterial spectrum is similar to that of benzyl penicillin C. It is used for less serious penicillin G sensitive infections D. All of the above are correct
Last Answer : D. All of the above are correct
Description : Despite having anticonvulsant action, diazepam is not used in the treatment of epilepsy because: A. It is not effective orally B. It causes sedation C. Its anticonvulsant action wanes off with chronic use D. Both ‘B’ and ‘C’ are correct
Last Answer : D. Both ‘B’ and ‘C’ are correct
Description : Captopril pretreatment: A. Inhibits the pressor action of angiotensin I B. Inhibits the pressor action of angiotensin II C. Potentiates the depressor action of bradykinin D. Both ‘A’ and ‘C’ are correct
Last Answer : D. Both ‘A’ and ‘C’ are correct
Description : The following statement is correct about buspirone: A. It interacts with benzodiazepine receptor as an inverse agonist B. It is a rapidly acting anxiolytic, good for panic states C. ... suppresses barbiturate withdrawal syndrome D. It has anxiolytic but no anticonvulsant or muscle relaxant propert
Last Answer : D. It has anxiolytic but no anticonvulsant or muscle relaxant property
Description : Select the drug that is used orally to treat scabies: A. Permethrin B. Ivermectin C. Praziquantel D. Crotamiton
Last Answer : B. Ivermectin
Description : What is true about human interferon α: A. It is used to treat HIV infection B. It is used to treat Kaposi‘s sarcoma in AIDS patients C. It is curative for hepatitis B virus infection D. It is active orally
Last Answer : B. It is used to treat Kaposi‘s sarcoma in AIDS patients