Description : Parenteral testosterone therapy in a boy can cause the following adverse effects except: A. Gynaecomastia B. Acne C. Cholestatic jaundice D. Precocious puberty
Last Answer : C. Cholestatic jaundice
Description : Practically all antineoplastic drugs can produce the following toxic effects except: A. Depression of leucocyte count B. Mucositis C. Cardiomyopathy D. Oligozoospermia
Last Answer : C. Cardiomyopathy
Description : Adverse effects of ciprofloxacin are referable primarily to the following except: A. Gastrointestinal tract B. Kidney C. Skin D. Nervous system
Last Answer : B. Kidney
Description : Select the diuretic that can cause gynaecomastia, hirsutism and menstrual disturbance as a side effect on long-term use: A. Amiloride B. Spironolactone C. Metolazone D. Acetazolamide
Last Answer : B. Spironolactone
Description : The following adverse effect can occur even long after withdrawal of the offending drug: A. Paradoxical tachycardia B. Tardive dyskinesia C. Malignant hyperthermia D. Gynaecomastia
Last Answer : B. Tardive dyskinesia
Description : The constellation of adverse effects associated with nonsteroidal antiinflammatory drugs include the following except: A. Sedation B. Gastric irritation C. Fluid retention D. Rashes
Last Answer : A. Sedation
Description : 16.10 Hyperprolactinemia can cause the following except: A. Amenorrhoea B. Gynaecomastia C. Multiple ovulation D. Depressed fertility
Last Answer : . Multiple ovulation
Description : Health benefits afforded by the combined estrogenprogestin oral contraceptive pill include the following except: A. Reduced menstrual blood loss B. Lower risk of fibrocystic breast disease C. Lower risk of myocardial infarction D. Lower risk of endometrial carcinoma
Last Answer : . Lower risk of myocardial infarction
Description : Adverse consequences of excess mineralocorticoid action include the following except: A. Na+ and water retention B. Acidosis C. Aggravation of CHF associated myocardial fibrosis D. Rise in blood pressure
Last Answer : B. Acidosis
Description : Fluconazole offers the following advantage(s) over ketoconazole: A. It is longer acting B. Its absorption from stomach is not dependent on gastric acidity C. It produces fewer side effects D. All of the above
Last Answer : D. All of the above
Description : Fluconazole differs from ketoconazole in that: A. It is not active by the oral route B. It is a more potent inhibitor of drug metabolism C. It is not effective in cryptococcal meningitis D. It is unlikely to produce anti-androgenic side effects
Last Answer : D. It is unlikely to produce anti-androgenic side effects
Description : The following drugs are effective in systemic mycosis except: A. Terbinafine B. Itraconazole C. Ketoconazole D. Fluconazol
Last Answer : A. Terbinafine
Description : The following is applicable to itraconazole except: A. It has largely replaced ketoconazole for treatment of systemic mycosis B. It does not inhibit human steroid hormone synthesis C. It is ... the treatment of fungal meningitis D. It can interact with terfenadine to produce ventricular arrhythmias
Last Answer : C. It is preferred for the treatment of fungal meningitis
Description : The following statement is true about ketoconazole except: A. It is less toxic than amphotericin B B. It produces a slower response than amphotericin B in systemic mycosis C. Given orally it is the first line treatment for vaginal candidiasis D. It is not effective in fungal meningitis
Last Answer : C. Given orally it is the first line treatment for vaginal candidiasis
Description : Clomiphene citrate is indicated for the following condition/conditions: A. Female infertility due to anovular cycles B. Male infertility due to oligozoospermia C. Endometriosis D. Both 'A' and 'B'
Last Answer : D. Both 'A' and 'B'
Description : Adverse effects of ciprofloxacin are referable primarily to the following except (a) Gastrointestinal tract (b) Kidney (c) Skin (d) Nervous system
Last Answer : Ans: B
Description : Cyclosporine has the following attributes except: A. It selectively suppresses humoral immunity without affecting cell mediated immunity B. It is more active as immunosuppressant when administered before antigen exposure ... It is not toxic to the bone marrow D. Its major toxicity is kidney damage
Last Answer : A. It selectively suppresses humoral immunity without affecting cell mediated immunity
Description : The primary goals of asthma therapy include all of the following except (a) maintain normal activity levels (b) maintain control of symptoms (c) avoid adverse effects of asthma medications (d) prevent acute exacerbations and chronic symptoms (e) prevent destruction of lung tissue
Last Answer : Ans: E
Description : Potential adverse effects associated with aspirin include all of the following except (a) Gastrointestinal ulceration (b) Renal dysfunction (c) Enhanced methotrexate toxicity (d) Cardiac arrhythmias (e) Hypersensitivity asthma
Description : Gynaecomastia can occur as a side effect of: A. Bromocriptine B. Cimetidine C. Famotidine D. Levodopa
Last Answer : B. Cimetidine
Description : Long-term hydralazine therapy is likely to cause: A. Gynaecomastia B. Thrombocytopenia C. Haemolytic anaemia D. Lupus erythematosus
Last Answer : D. Lupus erythematosus
Description : 16.13 Gynaecomastia can be treated with: A. Chlorpromazine B. Cimetidine C. Bromocriptine D. Metoclopramide
Last Answer : C. Bromocriptine
Description : The following drug adverse effect is specially noted in men compared to women: A. Tardive dyskinesia due to neuroleptics B. Levodopa induced abnormal movements C. Ampicillin induced loose motions D. Ketoconazole induced loss of libido
Last Answer : D. Ketoconazole induced loss of libido
Description : The effects of diethyl carbamazine citrate in filariasis include the following except: A. Rapid symptomatic relief in acute filarial attack B. Renders filarial patients noninfective to mosquitoes ... Prolonged treatment may achieve radical cure by killing adult filarial worms lodged in lymphatics
Last Answer : C. Prolonged treatment induces regression of filarial elephantiasis
Description : Beneficial effects of β-adrenoceptor blockers in CHF include the following except: A. Antagonism of ventricular wall stress enhancing action of sympathetic overactivity B. Antagonism ... Prevention of pathological remodeling of ventricular myocardium D. Prevention of dangerous cardiac arrhythmias
Last Answer : B. Antagonism of vasoconstriction due to sympathetic overactivity
Description : The electrophysiological effects of digitalis on Purkinje fibres include the following except: A. Enhancement of resting membrane potential B. Decrease in the slope of phase-0 depolarization C. Increase in the rate of phase-4 depolarization D. Abbreviation of action potential duration
Last Answer : A. Enhancement of resting membrane potential
Description : The subjective effects of morphine include the following except: A. Dysphoria in many uninitiated individuals B. Euphoria in dependent subjects C. Visual hallucinations D. Detachment to self and surrounding
Last Answer : C. Visual hallucination
Description : The distinctive features of fluoxetine compared to the typical tricyclic antidepressants include the following except: A. It is less likely to produce cardiac arrhythmias in overdose B. It infrequently ... suffering from chronic somatic illness D. It does not block neuronal uptake of biogenic amines
Last Answer : D. It does not block neuronal uptake of biogenic amines
Description : Limitations of typical tricyclic antidepressants include the following except: A. Narrow safety margin B. Low oral bioavailability C. Frequent side effects D. Long latent period for response
Last Answer : B. Low oral bioavailability
Description : Side effects of cyclic progestin therapy include the following except: A. Headache B. Gastroesophageal reflux C. Breast dyscomfort D. Irregular bleeding
Last Answer : D. Irregular bleeding
Description : Metabolic effects that generally attend antiinflammatory doses of aspirin include the following except: A. Increased CO2 production B. Hepatic glycogen depletion C. Metabolic acidosis D. Compensated respiratory alkalosis
Last Answer : C. Metabolic acidosis
Description : The most important dose-limiting adverse effect of colchicine is: A. Sedation B. Kidney damage C. Diarrhoea D. Muscle paralysis
Last Answer : C. Diarrhoea
Description : The following is true of mefloquine: A. P. falciparum does not develop resistance to mefloquine B. Concurrent use of β blockers with mefloquine is contraindicated C. Neuropsychiatric reactions are the most important adverse effects of mefloquine D. All of the above
Last Answer : C. Neuropsychiatric reactions are the most important adverse effects of mefloquine
Description : Choose the drug whose single oral dose affords clinical cure of uncomplicated malaria caused by chloroquine sensitive/resistant P.falciparum as well as P. vivax: A. Quinine B. Mefloquine C. Artesunate D. Proguanil
Last Answer : B. Mefloquine
Description : An AIDS patient treated with zidovudine + lamivudine + nelfinavir developed intolerable adverse effects. Then: A. Dose of all three drugs should be reduced to half B. All three drugs should be stopped or substituted simultaneously C. The drugs should be stopped one by one D. Two drugs sh
Last Answer : B. All three drugs should be stopped or substituted simultaneously
Description : Antiretroviral therapy is not recommended in asymptomatic HIV infected subjects with CD4 cell count more than 350/µl because of the following reason(s): A. All antiretroviral drugs lose efficacy after ... C. The treated subjects may produce and transmit drug resistant virus D. All of the above
Description : The most important reason for using a combination of chemotherapeutic agents in the treatment of tuberculosis is: A. To prevent development of resistance to the drugs B. To obtain bactericidal effect C. To broaden the spectrum of activity D. To reduce adverse effects of the drugs
Last Answer : A. To prevent development of resistance to the drugs
Description : Clavulanic acid is combined with amoxicillin because: A. It kills bacteria that are not killed by amoxicillin B. It retards renal excretion of amoxicillin C. It counteracts the adverse effects of amoxicillin D. It inhibits beta lactamases that destroy amoxicillin
Last Answer : D. It inhibits beta lactamases that destroy amoxicillin
Description : A higher incidence of adverse effects to cotrimoxazole occurs when this drug is used for: A. Typhoid fever B. Whooping cough C. Pneumocystis carinii pneumonia in AIDS patients D. Chancroid
Last Answer : C. Pneumocystis carinii pneumonia in AIDS patients
Description : Which of the following adverse effects of neuroleptic drugs is positively correlated to the antipsychotic potency of the different compounds: A. Sedation B. Extrapyramidal motor disturbances C. Postural hypotension D. Lowering of seizure threshold
Last Answer : B. Extrapyramidal motor disturbances
Description : Which of the following adverse effects of levodopa has a delayed onset and increases in severity with continued therapy: A. Nausea and vomiting B. Postural hypotension C. Cardiac arrhythmia D. Abnormal movements
Last Answer : D. Abnormal movements
Description : What is true about use of amphotericin B in kala azar: A. It is currently the drug of choice B. It is more effective than ketoconazole C. It is indicated only in cases not responding to sodium stibogluconate D. Both 'B' and 'C' are correct
Last Answer : D. Both 'B' and 'C' are correct
Description : The drug of choice for Kala azar is: A. Pentamidine B. Amphotericin B C. Sodium stibogluconate D. Ketoconazole
Last Answer : C. Sodium stibogluconat
Description : Select the drug that is fungicidal and acts by inhibiting fungal squalene epoxidase enzyme: A. Ketoconazole B. Terbinafine C. Tolnaftate D. Hamycin
Last Answer : B. Terbinafine
Description : The only azole antifungal drug which has some activity against moulds like Aspergillus is: A. Itraconazole B. Fluconazole C. Miconazole D. Ketoconazole
Last Answer : A. Itraconazole
Description : Choose the azole antifungal drug which is used only topically: A. Ketoconazole B. Fluconazole C. Itraconazole D. Econazole
Last Answer : D. Econazole
Description : Which antifungal agent is effective in both dermatophytosis as well as systemic mycosis: A. Amphotericin B B. Griseofulvin C. Clotrimazole D. Ketoconazole
Last Answer : D. Ketoconazole
Description : Select the antifungal drug which is administered only by the oral route: A. Amphotericin B B. Ketoconazole C. Griseofulvin D. Tolnaftate
Last Answer : C. Griseofulvin
Description : The drug of choice for monilial diarrhoea is: A. Flucytosine B. Nystatin C. Natamycin D. Ketoconazole
Last Answer : B. Nystatin