Description : Cytotoxic T-cells can be recognized by which of the following cell surface marker? A- CD4 B- CD7 C- CD8 D- CD9
Last Answer : CD8
Description : The cytotoxic T cells have a_____ co-receptor while the helper T cells have a _____ co-receptor. a. CD8. CD4 b. CD4, CD8 c. MHCI, MHCII d. MHCII, MHCI
Last Answer : a. CD8. CD4
Description : Macrophages are professional antigen- presenting cells. The protein molecule through whichthey present antigen in human is A- actin B- nterleukin C- HLA D- .CD8
Last Answer : .CD8
Description : Performs and granzymes are found in a. Helper T cells. b. Antigen-presenting cells. c. Cytotoxic T cells. d. B cells.
Last Answer : c. Cytotoxic T cells.
Description : Macrophages are professional antigen- presenting cells. The protein molecule through which theypresent antigen in human is A.actin B.interleukin C.HLA D.CD8
Last Answer : D.CD8
Description : Which of the following is correct for CD8 T cells? A- CD8 T cells only recognize virus-infected cells B- CD8 T cell receptor recognizes epitopes that are also commonly recognized by B cells ... selection only D- CD8 T cells can kill individual virus-infected cells in a contact dependent fashion
Last Answer : CD8 T cells can kill individual virus-infected cells in a contact dependent fashion
Description : Type I ADR reactions is___________ a) Caused when T-cells bind to a specific antigen b) Caused by tissue injury c) IgE mediated d) Caused by cytotoxic antibodies
Last Answer : c) IgE mediated
Description : _____ cells have antibodies on their surface that perform receptor functions by binding to antigen (epitope). a. T b. B c. NK d. A-C are correct
Last Answer : b. B
Description : Which of the following expresses CD3 surface antigen? A- Granulocytes B- T cells C- Monocytes D- B cells
Last Answer : T cells
Description : What type of immune cell may control IgE-mediated hypersensitivities? a. Suppressor T cells b. Plasma cells c. Cytotoxic T cells d. Neutrophils
Last Answer : a. Suppressor T cells
Description : The early response in asthma is due to activity. a. Cytotoxic T Cell b. Basophil c. TH2 Cell And NI( Cell d. Dendritic Cells
Last Answer : c. TH2 Cell And NI( Cell
Description : Cytotoxic T cells release which 2 toxic proteins as they fight target cells? a. histamine and heparin b. perforin and granzymes c. interleukin and interferon d. lysozymes and cytokines
Last Answer : b. perforin and granzymes
Description : TH1 cells activate a. B cells. b. Killing of pathogens in macrophages. c. Cytotoxic T cells. d. Humoral immunity.
Last Answer : d. Humoral immunity
Description : The following are true about antigen presenting cells (APC): a. Langerhan's cells are the antigen presenting cells of the epidermis b. CD8+ cells only recognize antigen presenting cells bearing ... necrosis factor alpha (TNF ) can turn endothelial cells into antigen presenting cells d. all above
Last Answer : all above
Description : Severe combined immunodeficiency disease refers to a condition wherein a patient a. Cannot produce T and B cells. b. Interferon. c. Antigen-presenting cells. d. Hydrogen peroxide in phagocytes
Last Answer : a. Cannot produce T and B cells.
Description : Acquired immunity usually involves protein receptors on B and T cells that recognize discrete regions of the antigen called _____. a. haptens b. epitopes c. antibodies d. protein receptors
Last Answer : b. epitopes
Description : With regard to HLA class 1 antigen: a. they are expressed on all nucleated cells b. they are essential for viral antigen recognition by cytotoxic cells c. the genes for HLA class 1 molecules are located on chromosome 6 and 15 d. all above
Description : Which one of the following applies to the disease systemic lupus erythematosus (SLE)? a. It is a type of cytotoxic hypersensitivity. b. It is often accompanied by a butterfly rash. c. It is due to an overreaction of T lymphocytes. d. It is the result of a cellular hypersensitivity.
Last Answer : d. It is the result of a cellular hypersensitivity.
Description : CD 3 complex and p 56lck proteins are present in (A) Cytotoxic T cells (B) Helper T cells (C) Both (A) and (B) (D) None of these
Last Answer : Answer : D
Description : CD 4 is a transmembrane glycoprotein present in (A) Cytotoxic T cells (B) Helper T cells (C) Suppressor T cells (D) Memory T cells
Last Answer : Answer : A
Description : CD 8 is a transmembrane glycoprotein present in (A) Cytotoxic T cells (B) Helper T cells (C) Suppressor T cells (D) Memory T cells
Last Answer : Answer : C
Description : MHC Class III proteins include (A) Immunoglobulins (B) Components of complement system (C) T cells receptors (D) CD4 and CD8 proteins
Description : Clonal selection includes a. Antigen-receptor binding on B cells. b. Antibody secretion recognizing same epitope as on B cell receptors. c. Differentiation of B cells into plasma cells and memory cells. d. All the above (A—C) are correct.
Last Answer : d. All the above (A—C) are correct.
Description : The role of the M cell is to A- .trap virus in mucus and prevent entry B- induce apoptosis in virus-infected small intestinal epithelia cells C- pass bacteria or virus to underlying macrophages for ... and presentation of antigen D- they use their cilia to propel mucus out of the small intestine
Last Answer : pass bacteria or virus to underlying macrophages for processing and presentation of antigen
Description : A hybridoma cell a. Secretes monoclonal antibodies. b. Presents antigens on its surface. c. Secretes polyclonal antibodies. d. Is an antigen-presenting cell
Last Answer : d. Is an antigen-presenting cell
Description : Which of the following is exposed on the outer surface of a gram-negative bacterium?A- O-antigen of lipopolysaccharide (LPS) B- Polysaccharide portion of lipoteichoic acid (LTA) C- Braun lipoprotein D- .Electron transport system components
Last Answer : O-antigen of lipopolysaccharide (LPS)
Description : The transfusion reaction that arises from the mixing of incompatible blood types illustrates a/an a. Form of lupus erythematous. b. Type i hypersensitivity. c. Immune complex reaction. d. Cytotoxic hypersensitivity.
Last Answer : d. Cytotoxic hypersensitivity.
Description : A cytotoxic hypersensitivity would occur if blood type is transfused into a person with blood type a. A;AB b. 0; AB c. A; 0 d. 0; B
Last Answer : a. A;AB
Description : Regarding interferon: a. it is a virus specific molecules b. it acts by neutralizing exotoxin c. it enhances the histocompatibility antigen on cell surface and thereby activate the T cells d. it exerts its effect by integrating itself with the DNA of virus infected cells
Last Answer : it enhances the histocompatibility antigen on cell surface and thereby activate the T cells
Description : Human immunodeficiency virus destroys (A) Cytotoxic T cells (B) Helper T cells (C) B cells (D) Plasma cells
Last Answer : Answer : B
Description : Cytotoxic T cells release (A) Perforins (B) Interleukins (C) Colony stimulating factors (D) Tumour necrosis factor
Description : MHC Class II proteins, in conjunction with antigens, are recognised by (A) Cytotoxic T cells (B) Helper T cells (C) Suppressor T cells (D) Memory T cells
Description : MHC class I proteins, in conjunction with antigens are recognised by (A) Cytotoxic T cells (B) Helper T cells (C) Suppressor T cells (D) Memory T cells
Description : The most abundant T cells are (A) Cytotoxic T cells (B) Helper T cells (C) Suppressor T cells (D) Memory T cells
Description : The following are true : a. the HLA proteins are found within the cytoplasm of the cells b. HLA class I antigens are expressed on all cells with nuclei c. HLA class II antigens presents ... on chromosome 6 e. HLA tissue typing is carried out in all forms of transplantation to prevent rejection
Last Answer : HLA class I antigens are expressed on all cells with nuclei
Description : Cytotoxic T cells a) lyse cells infected with virus. Cytotoxic T cells play a role in graft rejection. b) are important in producing circulating antibodies. B cells are lymphocytes important in producing ... that decrease B-cell activity to a level at which the immune system is compatible with life.
Last Answer : a) lyse cells infected with virus. Cytotoxic T cells play a role in graft rejection.
Description : Numerous antibodies can be prepared, against one antigen, each binds to unique epitopes. How is this antibody diversity generated? A- By rearrangements of the DNA encoding the variable regions of the heavy ... proteins can physically change their shape to bind different epitopes D- Both (a) and (b)
Last Answer : Both (a) and (b)
Description : With regard to interleukins: a. IL-2 is produced mainly by CD8+ cells b. IL-3 stimulates the growth of haemopoietic stem cells c. IL-4 increases the production of IL-1 d. IL-6 stimulates acute phase protein synthesis
Last Answer : IL-6 stimulates acute phase protein synthesis
Description : In Type I hypersensitivity the first dose of antigen is the _____. a. Immunizing Dose b. Sensitizing Dose c. Allergizing Dose d. Activating Dose
Last Answer : b. Sensitizing Dose
Description : What is the advantage of a recombinant subunit vaccine? a. it can't cause disease b. adverse reactions are rare because only the important subunits of the antigen are included c. the vaccine is not made from blood fragments d. A-C are correct
Last Answer : d. A-C are correct
Description : Titer refers to a. The most concentrated antigen-antibody concentration showing a reaction. b. The first diluted antigen-antibody concentration showing a reaction. c. The precipitation line ... antigen-antibody reaction. d. The most dilute antigen-antibody concentration showing a reaction.
Last Answer : d. The most dilute antigen-antibody concentration showing a reaction.
Description : An attenuated vaccine contains a. Inactive toxins. b. Living, but slow growing (replicating) antigens. c. Killed bacteria. d. Noninfective antigen subunits.
Last Answer : b. Living, but slow growing (replicating) antigens.
Description : Which one of the following is not an antigen? a. A toxin b. A virus c. A bacterial cell d. All (A-C) are antigens
Last Answer : d. All (A-C) are antigens
Description : An antigen binding site on the IgG antibody is a combination of a. One variable region from a light chain and one from a heavy chain. b. Two variable regions from two light chains. c. Two ... from two heavy chains. d. One variable region from a constant region and one from a variable region.
Last Answer : a. One variable region from a light chain and one from a heavy chain.
Description : In which of the following case a large lattice is formed? A.Antibody is in excess B.Antigens and antibodies are in optimal proportion C.Antigen is in excess D.None of these
Last Answer : B.Antigens and antibodies are in optimal proportion
Description : Which of the following(s) is/are the determinants of antigenicity? A- Chemical nature B- Size of the antigen C- Foreignness D- All of these
Last Answer : All of these
Description : Chemically an antigen may be A- lipid B- protein C- polysaccharide D- any of these
Last Answer : any of these
Description : Which is not an antigen-presenting cell (or APC)? A- B cell B- .Polymorphonuclear leukocyte (or PMN) C- Dendritic cell D- All of the above
Last Answer : .Polymorphonuclear leukocyte (or PMN)
Description : The initiation of a humoral immune response involves a complex interaction of the antigen, cells and intercellular messengers. Which of the following statement(s) concerning the initiation of the ... various cellular components of the immune system d. An antigen must be a living microorganism
Last Answer : Answer: a, b Stimulation of the immune system occurs after a variety of antigen-presenting cells (B lymphocytes, macrophages, dendritic cells, and Langerhans cells) act to engulf ... polysaccharides), most antigens require coordinated efforts of the various cellular components of the immune system