CD 3 complex and p 56lck proteins are present in (A) Cytotoxic T cells (B) Helper T cells (C) Both (A) and (B) (D) None of these

CD 3 complex and p 56lck proteins are present in (A) Cytotoxic T cells (B) Helper T cells (C) Both (A) and (B) (D) None of these
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CD 4 is a transmembrane glycoprotein present in (A) Cytotoxic T cells (B) Helper T cells (C) Suppressor T cells (D) Memory T cells

Description : CD 4 is a transmembrane glycoprotein present in (A) Cytotoxic T cells (B) Helper T cells (C) Suppressor T cells (D) Memory T cells

Last Answer : Answer : A

CD 8 is a transmembrane glycoprotein present in (A) Cytotoxic T cells (B) Helper T cells (C) Suppressor T cells (D) Memory T cells

Description : CD 8 is a transmembrane glycoprotein present in (A) Cytotoxic T cells (B) Helper T cells (C) Suppressor T cells (D) Memory T cells

Last Answer : Answer : C

MHC Class II proteins, in conjunction with antigens, are recognised by (A) Cytotoxic T cells (B) Helper T cells (C) Suppressor T cells (D) Memory T cells

Description : MHC Class II proteins, in conjunction with antigens, are recognised by (A) Cytotoxic T cells (B) Helper T cells (C) Suppressor T cells (D) Memory T cells

Last Answer : Answer : B

MHC class I proteins, in conjunction with antigens are recognised by (A) Cytotoxic T cells (B) Helper T cells (C) Suppressor T cells (D) Memory T cells

Description : MHC class I proteins, in conjunction with antigens are recognised by (A) Cytotoxic T cells (B) Helper T cells (C) Suppressor T cells (D) Memory T cells

Last Answer : Answer : A

Human immunodeficiency virus destroys (A) Cytotoxic T cells (B) Helper T cells (C) B cells (D) Plasma cells

Description : Human immunodeficiency virus destroys (A) Cytotoxic T cells (B) Helper T cells (C) B cells (D) Plasma cells

Last Answer : Answer : B

The most abundant T cells are (A) Cytotoxic T cells (B) Helper T cells (C) Suppressor T cells (D) Memory T cells

Description : The most abundant T cells are (A) Cytotoxic T cells (B) Helper T cells (C) Suppressor T cells (D) Memory T cells

Last Answer : Answer : B

The cytotoxic T cells have a_____ co-receptor while the helper T cells have a _____ co-receptor. a. CD8. CD4 b. CD4, CD8 c. MHCI, MHCII d. MHCII, MHCI

Description : The cytotoxic T cells have a_____ co-receptor while the helper T cells have a _____ co-receptor. a. CD8. CD4 b. CD4, CD8 c. MHCI, MHCII d. MHCII, MHCI

Last Answer : a. CD8. CD4

Performs and granzymes are found in a. Helper T cells. b. Antigen-presenting cells. c. Cytotoxic T cells. d. B cells.

Description : Performs and granzymes are found in a. Helper T cells. b. Antigen-presenting cells. c. Cytotoxic T cells. d. B cells.

Last Answer : c. Cytotoxic T cells.

The following are true : a. the HLA proteins are found within the cytoplasm of the cells b. HLA class I antigens are expressed on all cells with nuclei c. HLA class II antigens presents the virus infected cells to cytotoxic T lymphocytes d. HLA genes are found on chromosome 6 e. HLA tissue typing is carried out in all forms of transplantation to prevent rejection

Description : The following are true : a. the HLA proteins are found within the cytoplasm of the cells b. HLA class I antigens are expressed on all cells with nuclei c. HLA class II antigens presents ... on chromosome 6 e. HLA tissue typing is carried out in all forms of transplantation to prevent rejection

Last Answer : HLA class I antigens are expressed on all cells with nuclei

Cytotoxic T cells release which 2 toxic proteins as they fight target cells? a. histamine and heparin b. perforin and granzymes c. interleukin and interferon d. lysozymes and cytokines

Description : Cytotoxic T cells release which 2 toxic proteins as they fight target cells? a. histamine and heparin b. perforin and granzymes c. interleukin and interferon d. lysozymes and cytokines

Last Answer : b. perforin and granzymes

The initiation of a humoral immune response involves a complex interaction of the antigen, cells and intercellular messengers. Which of the following statement(s) concerning the initiation of the humoral immune response is/are correct? a. Helper T lymphocytes stimulate B lymphocytes through secretion of cytokines such as interleukin 4 and 6 b. A number of cells can aid in presenting the antigen to the helper T cell including B lymphocytes and macrophages c. All antigens require coordinated efforts of the various cellular components of the immune system d. An antigen must be a living microorganism

Description : The initiation of a humoral immune response involves a complex interaction of the antigen, cells and intercellular messengers. Which of the following statement(s) concerning the initiation of the ... various cellular components of the immune system d. An antigen must be a living microorganism

Last Answer : Answer: a, b Stimulation of the immune system occurs after a variety of antigen-presenting cells (B lymphocytes, macrophages, dendritic cells, and Langerhans cells) act to engulf ... polysaccharides), most antigens require coordinated efforts of the various cellular components of the immune system

CD8 surface antigen is present in A- cytotoxic T cells B- .suppresssor T cells C- both (a) and (b) D- none of these

Description : CD8 surface antigen is present in A- cytotoxic T cells B- .suppresssor T cells C- both (a) and (b) D- none of these

Last Answer : both (a) and (b)

Cytotoxic T cells release (A) Perforins (B) Interleukins (C) Colony stimulating factors (D) Tumour necrosis factor

Description : Cytotoxic T cells release (A) Perforins (B) Interleukins (C) Colony stimulating factors (D) Tumour necrosis factor

Last Answer : Answer : B

Helper T cells release all the following except (A) Interleukins (B) Colony stimulating factors (C) Perforins (D) Tumour necrosis factor

Description : Helper T cells release all the following except (A) Interleukins (B) Colony stimulating factors (C) Perforins (D) Tumour necrosis factor

Last Answer : Answer : C

Helper T cells release (A) Interleukins (B) Colony stimulating factors (C) Tumour necrosis factor (D) All of these

Description : Helper T cells release (A) Interleukins (B) Colony stimulating factors (C) Tumour necrosis factor (D) All of these

Last Answer : Answer : B

What type of immune cell may control IgE-mediated hypersensitivities? a. Suppressor T cells b. Plasma cells c. Cytotoxic T cells d. Neutrophils

Description : What type of immune cell may control IgE-mediated hypersensitivities? a. Suppressor T cells b. Plasma cells c. Cytotoxic T cells d. Neutrophils

Last Answer : a. Suppressor T cells

The early response in asthma is due to activity. a. Cytotoxic T Cell b. Basophil c. TH2 Cell And NI( Cell d. Dendritic Cells

Description : The early response in asthma is due to activity. a. Cytotoxic T Cell b. Basophil c. TH2 Cell And NI( Cell d. Dendritic Cells

Last Answer : c. TH2 Cell And NI( Cell

TH1 cells activatea. B cells. b. Killing of pathogens in macrophages. c. Cytotoxic T cells. d. Humoral immunity.

Description : TH1 cells activate a. B cells. b. Killing of pathogens in macrophages. c. Cytotoxic T cells. d. Humoral immunity.

Last Answer : d. Humoral immunity

Cytotoxic T-cells can be recognized by which of the following cell surface marker? A- CD4 B- CD7 C- CD8 D- CD9

Description : Cytotoxic T-cells can be recognized by which of the following cell surface marker? A- CD4 B- CD7 C- CD8 D- CD9

Last Answer : CD8

Cytotoxic T cells a) lyse cells infected with virus. Cytotoxic T cells play a role in graft rejection.

Description : Cytotoxic T cells a) lyse cells infected with virus. Cytotoxic T cells play a role in graft rejection. b) are important in producing circulating antibodies. B cells are lymphocytes important in producing ... that decrease B-cell activity to a level at which the immune system is compatible with life.

Last Answer : a) lyse cells infected with virus. Cytotoxic T cells play a role in graft rejection.

Type I ADR reactions is___________ a) Caused when T-cells bind to a specific antigen b) Caused by tissue injury c) IgE mediated d) Caused by cytotoxic antibodies

Description : Type I ADR reactions is___________ a) Caused when T-cells bind to a specific antigen b) Caused by tissue injury c) IgE mediated d) Caused by cytotoxic antibodies

Last Answer : c) IgE mediated 

The following statement(s) is/are true concerning HIV infection. a. Initial screening with ELISA is highly sensitive but can be associated with a false positive rate of 25% b. Treatment with azidothymidine (AZD) appears to prolong survival when administered early in the disease c. Predisposition to infection in HIV infection is primarily due to reduction in the number of helper T cells d. Common infections in patients with AIDS are Pneumocystis, carinii pneumonia, CMV pneumonitis, Cryptococcus meningitis, and disseminated infection due to atypical mycobacteria

Description : The following statement(s) is/are true concerning HIV infection. a. Initial screening with ELISA is highly sensitive but can be associated with a false positive rate of 25% b. ... , carinii pneumonia, CMV pneumonitis, Cryptococcus meningitis, and disseminated infection due to atypical mycobacteria

Last Answer : Answer: b, c, d Acquired immunodeficiency syndrome (AIDS) is a syndrome caused by the human retrovirus (HIV-1) that infects T lymphocytes and causes severe immunosuppression. Individuals who ... to prolong survival when administered early in the course of disease and is considered routine therapy

Predominant cell types in typical chronic inflammation are all of the following EXCEPT: A A. Polymorphonuclear leukocytes B. Macrophages C. T helper lymphocytes D. NK cells

Description : Predominant cell types in typical chronic inflammation are all of the following EXCEPT: A A. Polymorphonuclear leukocytes B. Macrophages C. T helper lymphocytes D. NK cells

Last Answer : Polymorphonuclear leukocytes

At which stage of HIV infection does one usually show symptoms of AIDS? (a) Within 15 days of sexual contact with an infected person (b) When the infected retro virus enters host cells (c) When HIV damages large number of helper T  - lymphocytes (d) When the viral DNA is produced by reverse transcriptase

Description : At which stage of HIV infection does one usually show symptoms of AIDS? (a) Within 15 days of sexual contact with an infected person (b) When the infected retro virus enters host cells (c) ... large number of helper T  - lymphocytes (d) When the viral DNA is produced by reverse transcriptase

Last Answer : (c) When HIV damages large number of helper T  - lymphocytes

Booster immunizations are used to raise the antibody level by stimulating the _____ cells to induce the secondary antibody response. a. helper T b. B c. memory d. plasma

Description : Booster immunizations are used to raise the antibody level by stimulating the _____ cells to induce the secondary antibody response. a. helper T b. B c. memory d. plasma

Last Answer : c. memory

_____ T cells prevent autoreactive T cells from attacking self. a. Memory b. Helper c. Regulatory d. Effector

Description : _____ T cells prevent autoreactive T cells from attacking self. a. Memory b. Helper c. Regulatory d. Effector

Last Answer : c. Regulatory

The AIDS viruses specifically attack which kind of cell? a) B cells b) helper T cells c) killer T cells d) macrophages

Description : The AIDS viruses specifically attack which kind of cell? a) B cells b) helper T cells c) killer T cells d) macrophages

Last Answer : ANSWER: B -- HELPER T CELLS

MHC class I proteins are present on the surface of (A) B cells only (B) T cells only (C) Macrophages only(D) All cells

Description : MHC class I proteins are present on the surface of (A) B cells only (B) T cells only (C) Macrophages only(D) All cells

Last Answer : Answer : D

Which of the following statements regarding the complement system are true? a. Complement activation yields products which are directly cytotoxic as well as products which act indirectly via activated leukocytes b. Complement products referred to as anaphylatoxins include C1, C3a, C4a, and C5a c. The principal role of C5a is in bacterial opsonization d. The alternative and classical pathways converge proximal to generating the membrane attack complex (C5b-9)

Description : Which of the following statements regarding the complement system are true? a. Complement activation yields products which are directly cytotoxic as well as products which act indirectly via activated ... and classical pathways converge proximal to generating the membrane attack complex (C5b-9)

Last Answer : Answer: a, d The complement system is composed of two different but linked sequences, the classic and alternative pathways. The pathways involve serum proteins that act to amplify the inflammatory-immune ... the C5 level proximal to generating the membrane attack complex (C5b-9) (Figure 6-3)

The transfusion reaction that arises from the mixing of incompatible blood types illustrates a/an a. Form of lupus erythematous. b. Type i hypersensitivity. c. Immune complex reaction. d. Cytotoxic hypersensitivity.

Description : The transfusion reaction that arises from the mixing of incompatible blood types illustrates a/an a. Form of lupus erythematous. b. Type i hypersensitivity. c. Immune complex reaction. d. Cytotoxic hypersensitivity.

Last Answer : d. Cytotoxic hypersensitivity.

Which one of the following applies to the disease systemic lupus erythematosus (SLE)? a. It is a type of cytotoxic hypersensitivity. b. It is often accompanied by a butterfly rash. c. It is due to an overreaction of T lymphocytes. d. It is the result of a cellular hypersensitivity.

Description : Which one of the following applies to the disease systemic lupus erythematosus (SLE)? a. It is a type of cytotoxic hypersensitivity. b. It is often accompanied by a butterfly rash. c. It is due to an overreaction of T lymphocytes. d. It is the result of a cellular hypersensitivity.

Last Answer : d. It is the result of a cellular hypersensitivity.

The following cytotoxic drug acts by inhibiting depolymerization of tubulin and thus producing abnormal arrays of microtubules: A. Paclitaxel B. Vinblastine C. Etoposide D. Mitoxantrone (p. 774) 60.9 C 60.10 B 60.11 D 60.12 A Ai

Description : The following cytotoxic drug acts by inhibiting depolymerization of tubulin and thus producing abnormal arrays of microtubules: A. Paclitaxel B. Vinblastine C. Etoposide D. Mitoxantrone (p. 774) 60.9 C 60.10 B 60.11 D 60.12 A Ai

Last Answer : A. Paclitaxel

What is the function of the helper T cell?

Description : What is the function of the helper T cell? 

Last Answer : The helper T cells assist the immune process by helping other cells in the immune system to achieve an efficient immune response. In antibody- mediated immunity, the helper T cell helps recognize ... cytotoxic T cells. These cells are critical to both antibody mediated and cell- mediated immunity. 

Predominant cell types in typical chronic inflammatory reactions include all of the following EXCEPT: A A. Polymorphonuclear leukocytes B. Macrophages C. T helper lymphocytes D. None of these

Description : Predominant cell types in typical chronic inflammatory reactions include all of the following EXCEPT: A A. Polymorphonuclear leukocytes B. Macrophages C. T helper lymphocytes D. None of these

Last Answer : Polymorphonuclear leukocytes

Which one of the following statements is correct with respect to AIDS? (a) The HIV can be transmitted through eating food together with an infected person. (b) Drug addicts are least susceptible to HIV infection.(c) AIDS patients are being fully cured cent per cent with proper care and nutrition. (d) The causative HIV retrovirus enters helper T-lymphocytes thus reducing their numbers.

Description : Which one of the following statements is correct with respect to AIDS? (a) The HIV can be transmitted through eating food together with an infected person. (b) Drug addicts are least ... and nutrition. (d) The causative HIV retrovirus enters helper T-lymphocytes thus reducing their numbers.

Last Answer : (d) The causative HIV retrovirus enters helper T-lymphocytes thus reducing their numbers.

HIV that causes AIDS, first starts destroying (a) helper T-lymphocytes (b) thrombocytes (c) B-lymphocytes (d) leucocytes.

Description : HIV that causes AIDS, first starts destroying (a) helper T-lymphocytes (b) thrombocytes (c) B-lymphocytes (d) leucocytes.

Last Answer : (a) helper T-lymphocytes

To activate a bound helper T lymphocyte, the macrophage produces a. Interleukin-1 (IL-1) b. granzymes c. Interferon

Description : To activate a bound helper T lymphocyte, the macrophage produces a. Interleukin-1 (IL-1) b. granzymes c. Interferon

Last Answer : a. Interleukin-1 (IL-1)

The _____ cell contains on its surface a CD4 receptor site that enhances binding to the macrophage. a. Helper T b. molecular patterns (PAMPs) c. plasma d. B

Description : The _____ cell contains on its surface a CD4 receptor site that enhances binding to the macrophage. a. Helper T b. molecular patterns (PAMPs) c. plasma d. B

Last Answer : a. IgG

MHC Class III proteins include (A) Immunoglobulins (B) Components of complement system (C) T cells receptors (D) CD4 and CD8 proteins

Description : MHC Class III proteins include (A) Immunoglobulins (B) Components of complement system (C) T cells receptors (D) CD4 and CD8 proteins

Last Answer : Answer : D

T cells can recognise (A) Free antigens (B) Antigens bound to cells (C) Antigens bound to antibodies (D) Antigens bound to MHC proteins

Description : T cells can recognise (A) Free antigens (B) Antigens bound to cells (C) Antigens bound to antibodies (D) Antigens bound to MHC proteins

Last Answer : Answer : D

With regard to HLA class 1 antigen: a. they are expressed on all nucleated cells b. they are essential for viral antigen recognition by cytotoxic cells c. the genes for HLA class 1 molecules are located on chromosome 6 and 15 d. all above

Description : With regard to HLA class 1 antigen: a. they are expressed on all nucleated cells b. they are essential for viral antigen recognition by cytotoxic cells c. the genes for HLA class 1 molecules are located on chromosome 6 and 15 d. all above

Last Answer : all above

The following does not apply to cancer chemotherapy: A. Each treatment with a cytotoxic drug kills a constant number of malignant cells B. Drugs are generally used at maximum tolerated doses C. The same regimen which is palliative for a large solid tumour may be curative after surgical removal of the tumour D. Combination regimens using several drugs in succession are superior to single drug used continuously

Description : The following does not apply to cancer chemotherapy: A. Each treatment with a cytotoxic drug kills a constant number of malignant cells B. Drugs are generally used at maximum tolerated ... D. Combination regimens using several drugs in succession are superior to single drug used continuously

Last Answer : A. Each treatment with a cytotoxic drug kills a constant number of malignant cells

All the following statements about protooncogenes are true except (A) They are present in human beings (B) They are present in healthy cells (C) Proteins encoded by them are essential (D) They are expressed only when a healthy cell has been transformed into a cancer cell

Description : All the following statements about protooncogenes are true except (A) They are present in human beings (B) They are present in healthy cells (C) Proteins encoded by them are essential (D) They are expressed only when a healthy cell has been transformed into a cancer cell

Last Answer : Answer : D

Receptors for thyroid hormones are present (A) On the cell membrane (B) Across the cell membrane (C) Inside the cells (D) In association with G-proteins

Description : Receptors for thyroid hormones are present (A) On the cell membrane (B) Across the cell membrane (C) Inside the cells (D) In association with G-proteins

Last Answer : Answer : C

MHC class II proteins are present on the surface of (A) All cells (B) B lymphocytes only (C) Macrophages only (D) Macrophages and B lymphocytes

Description : MHC class II proteins are present on the surface of (A) All cells (B) B lymphocytes only (C) Macrophages only (D) Macrophages and B lymphocytes

Last Answer : Answer : D

The complex of sugar polymers and proteins which are patchily distributed on the plasma membranes of animal cells is called a) cellulose b) chitin c) glyocalyx d) cytoskeleton

Description : The complex of sugar polymers and proteins which are patchily distributed on the plasma membranes of animal cells is called a) cellulose b) chitin c) glyocalyx d) cytoskeleton

Last Answer : ANSWER: C -- GLYOCALYX

Hormone receptors that stimulate cAMP production (A) are part of a complex of two proteins that transform the external signal into internal cAMP production (B) are proteins distinct and separate from those that catalyze the production of cAMP (C) cause release of the catalytic subunit upon binding of the hormone (D) are not very specific and bind a number of different hormones

Description : Hormone receptors that stimulate cAMP production (A) are part of a complex of two proteins that transform the external signal into internal cAMP production (B) are proteins distinct and separate from those ... binding of the hormone (D) are not very specific and bind a number of different hormones

Last Answer : Answer : B

The Golgi complex (A) Synthesizes proteins (B) Produces ATP (C) Provides a pathway for transporting chemicals (D) Forms glycoproteins

Description : The Golgi complex (A) Synthesizes proteins (B) Produces ATP (C) Provides a pathway for transporting chemicals (D) Forms glycoproteins

Last Answer : D

a. The P wave represent the electrical excitation of the_____ b. The QRS complex represents the ____ of the ventricles. c. The end of T wave marks the

Description : a. The P wave represent the electrical excitation of the_____ b. The QRS complex represents the ____ of the ventricles. c. The end of T wave marks the

Last Answer : a. The P wave represent the electrical excitation of the_____ b. The QRS complex represents the ____ of ... The end of T wave marks the end of _____

a. The P wave represent the electrical excitation of the_____ b. The QRS complex represents the ____ of the ventricles. c. The end of T wave marks the

Description : a. The P wave represent the electrical excitation of the_____ b. The QRS complex represents the ____ of the ventricles. c. The end of T wave marks the

Last Answer : a. The P wave represent the electrical excitation of the_____ b. The QRS complex represents the ____ of ... The end of T wave marks the end of _____