What is the major indication for doing an oral glucose tolerance test (OGTT)?

What is the major indication for doing an oral glucose tolerance test (OGTT)? 
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1 Answer

Answer :

Patient has symptoms suggestive of diabetes mellitus, but fasting blood sugar value is inconclusive (between 100 and 126 mg/dl).
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A 35 year old male presents with weakness and tiredness. He is noted to be hyertensive. Electrolytes show a hypokalaemia and a hypomagnesaemia. What investigation would you select for this patient? 1) Colonoscopy 2) Plasma renin toaldosterone ratio 3) Serum amylase 4) Serum calcium 5) Oral glucose tolerance test

Description : A 35 year old male presents with weakness and tiredness. He is noted to be hyertensive. Electrolytes show a hypokalaemia and a hypomagnesaemia. What investigation would you select for this patient? ... Plasma renin toaldosterone ratio 3) Serum amylase 4) Serum calcium 5) Oral glucose tolerance test

Last Answer : Answers-2 The hypokalaemic hypertension with hypomagnesaemia suggests primary hyperaldosteronism. The most reliable assessment for this would be renin to aldosterone ratio.

What are the precautions to take before OGTT?

Description : What are the precautions to take before OGTT?

Last Answer : Patient should have a good carbohydrate diet for three days prior to the test. Patient should avoid insulin and oral antidiabetic drugs. Patient should fast overnight. Patient should not take any breakfast.

Impaired galactose tolerance test suggests (A) Defect in glucose utilisation (B) Liver cell injury (C) Renal defect (D) Muscle injury

Description : Impaired galactose tolerance test suggests (A) Defect in glucose utilisation (B) Liver cell injury (C) Renal defect (D) Muscle injury

Last Answer : Answer : B

An 16-year-old man presents with polyuria and polydipsia. Which of the following may confirm the diagnosis of diabetes mellitus? 1) A random plasma glucose of >7.5 mmol/L 2) A finding of 3+ ketonuria 3) An HbA1c of 7.0% 4) A fasting plasma glucose of 7.5 mmol/L 5) An abnormal glucose tolerance test

Description : An 16-year-old man presents with polyuria and polydipsia. Which of the following may confirm the diagnosis of diabetes mellitus? 1) A random plasma glucose of >7.5 mmol/L 2) A finding of 3+ ketonuria 3) An HbA1c of 7.0% 4) A fasting plasma glucose of 7.5 mmol/L 5) An abnormal glucose tolerance test

Last Answer : Answers-4 The diagnosis is usually relatively easy to confirm in a symptomatic subject. A random glucose of >11.1 mmol/L or a fasting glucose of >7.0 mmol/L would be regarded as ... haemoglobin (HbA1c) is also highly suggestive but not diagnostic. A glucose tolerance test is rarely needed.

Glucose tolerance test?

Description : Glucose tolerance test?

Last Answer : DefinitionThe glucose tolerance test is a laboratory method to check how the body breaks down (metabolizes) sugar.Alternative NamesOral glucose tolerance testHow the test is performedThe most common glucose tolerance ... the injection, and again at 1 and 3 minutes after the injection, although th

Acromegaly results in all the following except (A) Overgrowth of the bones of face, hands and feet (B) Increased stature (C) Enlargements of viscera (D) Impaired glucose tolerance

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Last Answer : Answer : B

Metallic constituent of “Glucose tolerance factor” is (A) Sulphur (B) Cobalt (C) Chromium (D) Selenium

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Glucose tolerance is decreased in (A) Diabetes mellitus (B) Hypopituitarisme (C) Addison’s disease (D) Hypothyroidism

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Glucose tolerance is increased in (A) Diabetes mellitus (B) Adrenalectomy (C) Acromegaly (D) Thyrotoxicosis

Description : Glucose tolerance is increased in (A) Diabetes mellitus (B) Adrenalectomy (C) Acromegaly (D) Thyrotoxicosis

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The normal glucose tolerance curve reaches peak is (A) 15 min (B) 1 hr (C) 2 hrs (D) 2 ½ hrs

Description : The normal glucose tolerance curve reaches peak is (A) 15 min (B) 1 hr (C) 2 hrs (D) 2 ½ hrs

Last Answer : B

What are other conditions which may cause impaired glucose tolerance?

Description : What are other conditions which may cause impaired glucose tolerance?

Last Answer : Alimentary glucosuria, renal glucosuria.

What is impaired glucose tolerance (IGT)?

Description : What is impaired glucose tolerance (IGT)? 

Last Answer : When fasting plasma glucose level is between 110 and 126 mg/dl and 2-hour post-glucose value is between 140 and 200 mg/dl.

The following is not a valid indication for parenteral iron therapy: A. Inadequate response to oral iron due to patient noncompliance B. Anaemia during pregnancy C. Severe anaemia associated with chronic bleeding D. Anaemia in a patient of active rheumatoid arthritis

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A test to evaluate detoxifying function of liver is (A) Serum albumin: globulin ratio (B) Galactose tolerance test (C) Hippuric acid test (D) Prothrombin time

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The best known and most frequently used test of the detoxicating functions of liver is (A) Hippuric acid test (B) Galactose tolerance test (C) Epinephrine tolerance test (D) Rose Bengal dye test

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Diazoxide is an effective hypotensive, but is not used in the long-term treatment of hypertension because: A. It impairs glucose tolerance by inhibiting insulin release B. It inhibits uric acid excretion C. It causes marked Na+ and water retention leading to development of tolerance D. All of the above

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Metabolic actions of estrogens tend to cause the following except: A. Anabolism B. Impaired glucose tolerance C. Rise in plasma LDL-cholesterol D. Salt and water retention

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Glucocorticoids impair carbohydrate tolerance by: A. Promoting gluconeogenesis in liver B. Depressing glucose uptake into skeletal muscles C. Inhibiting insulin secretion D. Both A and B are correct

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