Description : A patient receiving a class I antiarrhythmic agent on a chronic basis complains of fatigue, low-grade fever, and joint pain suggestive of systemic lupus erythematosus (SLE). The patient is most likely receiving (a) Lidocaine (b) Procainamide (c) Quinidine (d) Flecainide (e) Propranolol
Last Answer : Ans: B
Description : The following antiarrhythmic drug has the most prominent anticholinergic action: A. Disopyramide B. Quinidine C. Procainamide D. Lignocaine
Last Answer : A. Disopyramide
Description : Which of the following drugs is a class III antiarrhythmic agent that is effective in the acute management of atrial fibrillation or atrial flutter of recent onset ? (a) Bretylium (b) Lbutilide (c) Metoprolol (d) Disopyramide
Description : Procainamide differs from quinidine in the following respect (a) It does not cause paradoxical tachycardia (b) It has no alfa adrenergic blocking activity (c) It has little antivagal action (d) Both (b ... a) Pacemaker function (b) Resting potential (c) Action potential duration (d) All of the above
Last Answer : Ans: D
Description : Which of the following drugs is a class IV antiarrhythmic that is primarily indicated for the treatment of supraventricular tachyarrhythmias? (a) Lbutilide (b) Mexiletine (c) Diltiazem (d) Quinidine (e) Propranolol
Last Answer : Ans: C
Description : Which of the following has the longest half-life of all antiarrhythmic drugs? (a) Adenosine (b) Amiodarone (c) Disopyramide (d) Esmolol (e) Flecainide
Description : A 16-year-old-girl is found to have paroxysmal attacks of rapid heart rate. The antiarrhythmic of choice in most cases of acute AV nodal tachycardia is (a) Adenosine (b) Amiodarone (c) Flecainide (d) Propranolol (e) Quinidine
Last Answer : Ans: A
Description : Which of the following cardiovascular agents is classified chemically as a glycoside? (a) Nifedipine (b) Digoxin (c) Flecainide (d) Cholestyramine (e) Warfarin
Description : Hypothyroidism is a possible consequence of prolonged therapy with (a) Procainamide (b) Mexiletine (c) Sotalol (d) Amiodarone
Description : Lidocaine is the preferred antiarrhythmic for emergency control of cardiac arrhythmias following acute myocardial infarction because (a) It has a rapidly developing and titratable antiarrhythmic action (b) It casues ... efficacy in atrial as well as ventricular arrhythmias (d) Both (a) and (b)
Description : The action of quinidine differs from that of digitalis in (a) Decreasing irritability of cardiac muscle (b) Preventing passage of impulses to the ventricle (c) Increasing irritability of heart muscle (d) Reducing conductivity (e) None of the above
Description : Which of the following agents has a direct effect on the AV mode, delaying calciumchannel depolarization? (a) Lidocaine (b) Diltiazem (c) Bretylium (d) Quinidine (e) Lbutilide
Description : Which one of the following drugs predictably prolongs the PR interval and increases cardiac contractility? (a) Digoxin (b) Lidocaine (c) Propranolol (d) Quinidine (e) Verapamil
Description : Which one of the following drugs increase digoxin plasma concentration by a pharmacokinetic mechanism? (a) Captopril (b) Hydrochorothiazide (c) Lidocaine (d) Quinidine (e) Sulfasalazine
Description : Which of the following drugs is preferred for termination of paroxysmal supraventricular tachycardia (a) Digoxin (b) Quinidine (c) Propranolol (d) Verapamil
Description : Quinidine is now used primarily for (a) Conversion of auricular fibrillation to sinus rhythm (b) Control of ventricular rate in atrial flutter (c) Termination of ventricular tachycardia (d) Prevention of recurrences of atrial and ventricular extrasystoles/tachycardias
Description : Quinidine can cause paradoxical tachycardia in a patient of (a) Stick sinus syndrome (b) Auricular extrasystoles (c) Auricular fibrillation (d) Ventricular extrasystoles
Description : The following antiarrhythmic drug accumulates in the body for a very long time: A. Procainamide B. Mexiletine C. Bretylium D. Amiodarone
Last Answer : D. Amiodarone
Description : The following is true of procainamide except: A. It generates an active metabolite in the body B. Its plasma half-life is longer than that of quinidine C. On long-term use, it ... erythematosus like illness D. It is effective in many cases of ventricular extrasystoles, not responding to lignocaine
Description : Procainamide differs from quinidine in the following respect(s): A. It does not cause paradoxical tachycardia B. It has no α adrenergic blocking activity C. It has little antivagal action D. Both ‘B’ and ‘C’ are corre
Last Answer : D. Both ‘B’ and ‘C’ are correct
Description : Procainamide differs from quinidine in the following respect(s): A. It does not cause paradoxical tachycardia B. It has no α adrenergic blocking activity C. It has little antivagal action D. Both ‘B’ and ‘C’ are correct
Description : A hypertensive patient has been using nifedipine for some time without untoward effects. If he experiences a rapidly developing enhancement of the antihypertensive effect of the drug, it is probably due to ... ) Grapefruit juice (d) Induction of drug metabolism (e) Over - the - counter decongestants
Description : For treating the patient with congestive heart failure (CHF), which of the following dosages of dopamine is selected for its positive inotropic effects? (a) 2.0 mg/kg/min (b) 5–10 mg/kg/min (c) 10–20 mg/kg/min (d) 40 mg/kg/min (e) 40 mg/kg/min
Description : Because of proven beneficial effects on “cardiac remodeling”, these agents are now indicated as first line therapy in CHF patients. Which of the following is representative of this group of drugs? (a) Hydrochlorothiazide (b) Enalapril (c) Furosemide (d) Carvedilol (e) Bumetanide
Description : Choose the antiarrhythmic drug which prolongs action potential, can aggravate atrioventricular block but not heart failure, and has broad spectrum utility in acute as well as chronic, and ventricular as well as supraventricular arrhythmias: A. Quinidine B. Amiodarone C. Mexiletine D. Diltiazem
Last Answer : B. Amiodarone
Description : The limitations of quinidine in the treatment of cardiac arrhythmias include the following except: A. It has narrow spectrum antiarrhythmic activity B. It is not tolerated by many patients C. It can precipitate myocardial decompensation D. It can cause marked hypotension
Last Answer : A. It has narrow spectrum antiarrhythmic activity
Description : The antiarrhythmic drug which decreases both rate of depolarization (phase 0) as well as rate of repolarization (phase 3) of myocardial fibres is: A. Lignocaine B. Propranolol C. Quinidine D. Verapamil
Last Answer : C. Quinidine
Description : Select the most suitable antiarrhythmic drug for counteracting ventricular extrasystoles due to digoxin toxicity: A. Lignocaine B. Quinidine C. Verapamil D. Amiodarone
Last Answer : A. Lignocaine
Description : Therapeutic dose of digoxin in a normal individual has the following effects, except (a) Increase in the speed of myocardial contractility (b) No significant change in cardiac output (c) Relaxation of peripheral vascular bed (d) Increase in the force of myocardial contractility
Description : Though nitrates and calcium channel blockers are both vasodilators, they are used concurrently in angina pectoris because (a) They antagonize each other's side effects (b) Nitrates primarily reduce preload while calcium ... load (c) Nitrates increase coronary flow while calcium (d) Both (b) and (c)
Description : Mary has a family history of heart disease and wonders if garlic would be beneficial to her. Which of the following statements is correct about garlic? (a) Enteric-coated tablets release their contents in ... (c) The safety of garlic in pregnancy is unknown (d) Garlic does not interact with warfarin
Description : Tolerance to nitroglycerin may be overcome by (a) Initially using the largest safe dose of the drug (b) Using other nitrites (c) Temporarily discontinuing the drug for one or two weeks (d) Use of higher doses (e) None of the above
Description : The chief use of levoarterenol is to treat (a) Shock (b) Diabetes (c) Hypertension (d) Cardiac arrhythmias (e) Iron deficiencies
Description : Regarding verapamil, which one of the following statements is false? (a) Angina pectoris is an important indication for the use of verapamil (b) Contraindicated in the asthmatic patient (c) ... phase of the action potential in AV nodal cells (e) Used in management of supraventricular tachycardias
Description : Which of the following is used to lower blood lipid levels? (a) Trimethadione (b) Clofibrate (c) Flucytosine (d) Coumarin (e) Propranolol
Description : In case of acute pain of angina pectoris the most effective treatment would be to administer (a) Mannitol hexanitrate (b) Erythrityl tetranitrate (c) Sodium nitrate (d) Pentaerythritol tetranitrate (e) Nitroglycerin
Last Answer : Ans: E
Description : The action of digitalis is enhanced by (a) Sodium (b) Calcium (c) Magnesium (d) Potassium (e) Chloride
Description : Overuse of digitalis may result in (a) Habituation (b) Tolerance (c) Addiction (d) Physical dependence (e) Cummulative poisoning
Description : Acute renal failure (ARF) may be caused by all of the following except (a) Acute tubular necrosis (ATN) due to drug therapy (e.g., aminoglycosides, contrast media) (b) Severe hypotension ... (c) Decreased cardiac output, as from congestive heart failure (d) Hemolysis, myoglobinuria (e) Hyperkalemia
Description : Unfractionated heparin binds to antithrombin III and inactivates clotting factor(s) (a) Xa (b) Ixa (c) Iia (d) All of the above (e) None of the above
Description : When digoxin is used in a patient with congestive heart failure (CHF), it works by exerting a positive effect on (a) Stroke volume (b) Total peripheral resistance (c) Heart rate (d) Blood pressure (e) Venous return
Description : Which of the following combinations of drugs, when used together, reduce both preload and afterload? (a) Nitroglycerin and isosorbide dinitrate (b) Hydralazine and isosorbide dinitrate (c) Captopril and methyldopa (d) Prazosin and angiotension II (e) Hydralazine and methyldopa
Description : Which of the following groups of symptoms is most often associated with a patient who has right-sided heart failure? (a) Nocturia, rales, paroxysmal nocturnal dyspnea (b) Paroxysmal ... distention (e) Paroxysmal nocturnal dyspnea, jugular venous distention, abdominal distention, shortness of breath
Description : Maximal medical therapy for treating angina pectoris is represented by which of the following choices? (a) Diltiazem, verapamil, nitroglycerin (b) Atenolol, isoproterenol, diltiazem (c) Verapamil, nifedipine, propranolol (d) Isosorbide, atenolol, diltiazem (e) Nitroglycerin, isosorbide, atenolol
Description : Which of the following agents used in prinzmetal’s angina has spasmolytic actions, which increase coronary blood supply? (a) Nitroglycerin (b) Nifedipine (c) Timolol (d) Isosorbide mononitrate (e) Propranolol
Description : Myocardial oxygen demand is increased by all of the following factors except (a) Exercise (b) Smoking (c) Cold temperatures (d) Isoproterenol (e) Propranolol
Description : Exertion–induced angina, which is relieved by rest, nitroglycerin, or both, is referred to as (a) Prinzmetal’s angina (b) Unstable angina (c) Classic angina (d) Variant angina (e) Preinfarction angina
Description : Which of the following cyclotron produced radiopharmaceuticals is used for assessing regional myocardial perfusion as part of an exercise stress test? (a) Thallous chloride 201TI USP (b) Sodium iodide 123I (c) Gallium citrate 67Ga USP (d) Indium 111In pentetate (e) Cobalt 57Co cyanocobalamin
Description : What drug is used to prevent embolism in the lung and during myocardial infarction? (a) Alteplase (b) Human growth hormone (c) Granulocyte–macrophage colony – stimulating factor (GM–CSF) (d) EPOGEN (EPO) (e) None of the above
Description : A 54-year-old woman with severe hypercholesterolemia is to be treated with a combination of niacin and atorvastatin. With this drug combination, it is important that the patient be monitored closely for signs of (a) Agranulocytosis (b) Gallstones (c) Lactic acidosis (d) Myopathy (e) Thyrotoxicosis