What is pentazocaine's mechanism of action?

1 Answer

Answer :

Pentazocaine acts on kappa-opioid receptors and partially actson mu-opioid receptors of the central nervous system. This leads tothe ascending pathway of pain being inhibited resulting inanalgesia, sedating, and respiratory depression.

Related questions

Description : What is pentazocaine's mechanism of action?

Last Answer : Pentazocaine acts on kappa-opioid receptors and partially actson mu-opioid receptors of the central nervous system. This leads tothe ascending pathway of pain being inhibited resulting inanalgesia, sedating, and respiratory depression.

Description : How is Orencia (abatacept) different from Enbrel, Humira, Remicade, and Anakinra? What is its mechanism of action?

Last Answer : Are these drugs? What do they purport to treat? None of the names sound familiar to me.

Description : What is the role of second messenger in the mechanism of protein hormone action? -Biology

Last Answer : answer:

Description : Lock and Key mechanism of enzyme action? -Biology

Last Answer : answer:

Description : Induced fit mechanism of enzyme action -Biology

Last Answer : answer:

Description : What is Xanax (Alprazolam)mechanism of action - Genericambienonline?

Last Answer : In this pandemic, it's very natural for the person to be surrounded with much anxiety and panic. Both the professional and personal lives do suffer due to anxiety and panic that a person takes. ... individual. Life events like the death of a close one, suffering from a severe medical ailment. Even

Description : During mechanism of action of insulin, protein kinase C is activated by

Last Answer : During mechanism of action of insulin, protein kinase C is activated by A. `PIP_2` B. `IP_3` C. `DG ` D. `Ca^(2+)`

Description : What is the mechanism of action of hormones?

Last Answer : activation of mRNA, which increases protein synthesis in the cell

Description : Antibacterial agents can be classified with regard to their structure, mechanism of action, and activity pattern against various types of bacterial pathogens. Which of the following ... are both bacteriostatic d. Sulfonamides and trimethoprim act synergistically to inhibit purine synthesis

Last Answer : Answer: a, b, d Penicillins, cephalosporins, and monobactams possess a b-lactam ring of some type and act to bind bacterial division plate proteins, thus inhibiting cell wall ... act in different mechanisms to inhibit protein synthesis, therefore two agents in combination act synergistically

Description : Mini-dose heparin has been shown to be useful in the prophylaxis of postoperative venous thrombosis. Mechanism(s) by which low-dose heparin is/are thought to protect against venous ... aggregation and subsequent platelet release action d. A mild prolongation of activated partial thromboplastin time

Last Answer : Answer: a, b, c Low-dose heparin is thought to protect against venous thrombosis through three different mechanisms. First, antithrombin III activity with its inhibition of activated Factor X is ... release reaction. The standard doses of heparin administered (5000 units bid) does not affect aPTT

Description : The biochemical mechanism of action of digitalis is associated with (a) A decrease in calcium uptake by the sarcoplasmic reticulum (b) An increase in ATP synthesis (c) A modification of the actin molecule (d) An increase in systolic intracellular calcium levels (e) A block of sodium/calcium exchange

Last Answer : Ans: D

Description : Which of the following best describes the mechanism of action of scopolamine ? (a) Irreversible antagonist at nicotinic receptors (b) Irreversible antagonist at muscarinic receptors (c) ... receptors (d) Reversible antagonist at muscarinic receptors (e) Reversible antagonist at nicotinic receptors

Last Answer : Ans: D

Description : The mechanism of action of cyclosporine involves (a) Activation of calcineurin (b) Binding to cyclophilin to cause inhibition of a cytoplasmic phosphatase (c) Blockade of interleukin – 2- receptors (d) Inhibition of phospholipase A2 (e) Suppression of bone marrow progenitors

Last Answer : Ans: B

Description : The most important mechanism by which tetracycline antibiotics exert antiimicrobial action is (a) They chelate Ca2+ ions and alter permeability of bacterial cell membrane (b) They bind to 30S ribosomes ... peptide chain in the bacteria (d) They interfere with DNA mediated RNA synthesis in bacteria

Last Answer : Ans: B

Description : The mechanism of antibacterial action of tetracycline involves (a) Binding to a component of the 50S ribosomal subunit (b) Inhibition of translocase activity (c) Blockade of binding of ... (d) Selective inhibition of ribosomal peptidyl transferases (e) Inhibition of DNA-dependent RNA polymerase

Last Answer : Ans: C

Description : Which of the following factors does not govern the mechanism of petroleum formation from organic sources? (A) pH of the soil (B) Bacterial action (C) Heat (D) Pressure

Last Answer : (A) pH of the soil

Description : General mechanism of size reduction in intermediate and fine grinder is by (A) Cutting action (B) Compression (C) Compression and tearing (D) Impact and attrition

Last Answer : (D) Impact and attrition

Description : What is the mechanism of action of prostaglandins?

Last Answer : Prostaglandins are local hormones, and function through G-protein coupled receptors In most tissues, PGE increases cAMP level. But in adipose tissue and in renal tubular cells, PGE lowers cAMP level.

Description : What is the mechanism of action of aspirin?

Last Answer : Aspirin acetylates serine in the active site and irreversibly inhibits the cyclo-oxygenase.

Description : What is the mechanism of action of insulin?

Last Answer : Insulin acts by binding to membrane receptor, on the target cells.

Description : What is the mechanism of action of adrenaline?

Last Answer : Adrenaline increases cyclic AMP level which activates glycogen phosphorylase.

Description : What is the mechanism of inhibitory action of Di-isopropyl fluoro phosphate?

Last Answer : It inhibits enzymes with serine in their active centres, e.g. acetylcholine esterase.

Description : Pharmacy deals with;  B A. Mechanism of action of drug B. Preparation of drug C. Identification of drug D. Metabolism of drug

Last Answer : Preparation of drug

Description : Identify A, B and C in the diagramatic representation of the mechanism of hormone action. B A Response 1 C Physiological Responses Select the correct option from the following. (a) A-Steroid Hormone; B- ... ; C - Second Messenger (d) A-Protein Hormone; B-Cyclic AMP; C-Hormone-receptor Complex

Last Answer : (b) A-Protein Hormone; B-Receptor; C-Cyclic AMP

Description : The mechanism which changes the value of manipulated variable in response to the output signal from the control unit is called the (A) Final control element (B) On-off control (C) Floating control action (D) None of these

Last Answer : Option A

Description : Trichloroacetic acid, a strong acid, has been used by dentists for chemical cautery of hypertrophic tissue and aphthous ulcers; its mechanism of action is, BOUCHERS P 194 A. Thermodynamic ... Activation of tissue enzymes C. Osmotic pressure D. Protein precipitation (PPT) E. Neutralization

Last Answer : D. Protein precipitation (PPT)

Description : A 25 years old school teacher Para 1 wants to use oral contraceptive pills for contraception. She is asking about the mode of action of oral contraceptive pills. The mechanism of action of ... atrophy. c) Increasing cervical mucous hostility. d) Inducing endometritis. e) Inhibiting prolactin.

Last Answer : a) Inhibiting ovulation by suppression of serum FSH.

Description : Herbicide Resistance can be managed through a). Stop to Use of herbicides with the same mechanism of action b). Use proactive weed control c). Use of post emergence herbicides with at least one mechanism of action d). All of the above

Last Answer : d). All of the above

Description : The most probable mechanism of action of mebendazole is: A. Depolarization of membrane and spastic paralysis of the worm B. Hyperpolarization of membrane and flaccid paralysis of the worm C. Loss of ... inhibition of glucose uptake in the worm D. Tegument damage and leakage of contents of the worm

Last Answer : C. Loss of intracellular microtubules and inhibition of glucose uptake in the worm

Description : The most probable mechanism of action of imidazole antifungal drugs is: A. They bind to ergosterol in fungal cell membrane and make it leaky B. They interfere with ergosterol synthesis by fungi C. They interfere with fungal mitosis D. They block oxidative phosphorylation in fungi

Last Answer : B. They interfere with ergosterol synthesis by fungi

Description : The most important mechanism by which tetracycline antibiotics exert antimicrobial action is: A. They chelate Ca2+ ions and alter permeability of bacterial cell membrane B. They bind to 30S ribosomes ... peptide chain in the bacteria D. They interfere with DNA mediated RNA synthesis in bacteria

Last Answer : B. They bind to 30S ribosomes and inhibit bacterial protein synthesis

Description : The most likely mechanism of antihypertensive action of thiazide diuretics in the long-term is: A. Reduction of circulating blood volume B. Reduction in cardiac output C. Decreased sympathetic tone D. Reduction in total peripheral vascular resistance and improved compliance of resistance vessels

Last Answer : D. Reduction in total peripheral vascular resistance and improved compliance of resistance vessels

Description : The most probable mechanism of anticonvulsant action of phenytoin is: A. Facilitation of GABAergic inhibitory transmission B. Hyperpolarization of neurones C. Interaction with Ca2+ channels to promote Ca2+ influx D. Prolongation of voltage sensitive neuronal Na+ channel inactivation

Last Answer : D. Prolongation of voltage sensitive neuronal Na+ channel inactivation

Description : The primary mechanism of action of benzodiazepines is: A. Dopamine antagonism B. Adenosine antagonism C. Opening of neuronal chloride channels D. Facilitation of GABA-mediated chloride influx

Last Answer : D. Facilitation of GABA-mediated chloride influx

Description : The mechanism of action of barbiturates differs from that of benzodiazepines in that they: A. Do not affect the GABA-benzodiazepine receptor-chloride channel complex B. Act as inverse agonists at the ... without affecting its life time D. Have both GABA-facilitatory as well as GABA-mimetic actions

Last Answer : D. Have both GABA-facilitatory as well as GABA-mimetic actions

Description : e primary mechanism by which general anaesthetics produce their action is: A. Affecting receptor operated ion channels in cerebral neurones B. Blocking voltage sensitive Na+ channels in neuronal ... activity of cerebral neurones D. Blocking production of high energy phosphates in the brain

Last Answer : A. Affecting receptor operated ion channels in cerebral neurones

Description : The primary mechanism of action of the combined estrogen-progestin oral contraceptive pill is: A. Production of cervical mucus hostile to sperm penetration B. Suppression of FSH and ... Making endometrium unsuitable for implantation D. Enhancing uterine contractions to dislodge the fertilized ovum

Last Answer : B. Suppression of FSH and LH release

Description : The most important mechanism of antiinflammatory action of glucocorticoids is: A. Inhibition of lysosomal enzymes B. Restriction of recruitment of inflammatory cells at the site of inflammation C. Antagonism of action of interleukins D. Suppression of complement function

Last Answer : B. Restriction of recruitment of inflammatory cells at the site of inflammation

Description : Write the mechanism of corrosion of metal due to action of oxygen.

Last Answer : Mechanism: Metallic surfaces when exposed to air undergo oxidation and the process of corrosion is represented by the equation.   A thin oxide layer is formed on the metal surface and the nature of this film decides further action depending upon the film so produced.