Description : Which one of the following is characteristic of captopril and enalapril ? (a) Competitively blocks angiotensim II at its receptor (b) Decreases angiotensin II concentration in the blood (c) Decreases ... and decreases potassium in the blood (e) Decreases sodium and increases potassium in the urine
Last Answer : Ans: B
Description : Actions of angiotensin II include: a. increases the release of aldosterone b. reduces renin release from the kidney c. vasodilatation d. promotes microalbuminuria
Last Answer : promotes microalbuminuria
Description : Which one of the following statements is correct with respect to kidney function regulation? (a) When someone drinks lot of water, ADH release is suppressed. (b) Exposure to cold temperature ... During summer when body loses lot of water by evaporation, the release of ADH is suppressed.
Last Answer : (a) When someone drinks lot of water, ADH release is suppressed.
Description : Angiotensin II causes rise in blood pressure by: A. Direct vasoconstriction B. Releasing adrenaline from adrenal medulla C. Increasing central sympathetic tone D. All of the above
Last Answer : D. All of the above
Description : All the following statements about angiotensin are true except (A) Its precursor is an α2-globulin (B) Its active form is an octapeptide (C) It is a vasodilator (D) It increases the secretion of aldosterone
Last Answer : Answer : C
Description : True statements about aldosterone include: a. secretion is mainly under the control of adrenocorticotrophic (ACTH) hormone secretion b. increases hepatic gluconeogenesis c. its secretion is stimulated by angiotensin d. in the kidney, mainly acts on the proximal convoluted tubules
Last Answer : its secretion is stimulated by angiotensin
Description : Assertion `:-` Angiotensin II, activates the adrenall cortex to release aldosterone. Reason `:-` Aldosterone causes reabsorption of `Na^(o+)` and wate
Last Answer : Assertion `:-` Angiotensin II, activates the adrenall cortex to release aldosterone. Reason `:-` ... D. If both Assertion & Reason are false.
Description : Assertion `:-` Angiotensin II is a powerful vasconstrictor Reason `:-` Aldosterone causes reabsorption of `Na^(+)` and water from distal parts of the
Last Answer : Assertion `:-` Angiotensin II is a powerful vasconstrictor Reason `:-` Aldosterone causes reabsorption of ... D. If both Assertion & Reason are false.
Description : Vasoconstrictor effect of ADH is mediated by (A) cAMP (B) cGMP (C) Protein kinase C (D) Angiotensin II
Description : Aldosterone release is stimulated by (A) α2-Globulin (B) Renin (C) Angiotensin II (D) Growth hormone
Description : In the rennin-angiotensin system the primary hormone is (A) Angiotensinogen (B) Angiotensin I (C) Angiotensin II (D) Angiotensin III
Description : Prostaglandin synfhesis is increased by activating phospholipases by (A) Mepacrine (B) Angiotensin II (C) Glucocorticoids (D) Indomenthacin
Last Answer : Answer : B
Description : Agents that often cause vasoconstriction include all of the following except (a) Angiotensin II (b) Methysergide (c) PGF2a (d) Prostacyclin (e) Thromboxane
Last Answer : Ans: D
Description : Aldosterone secretion is controlled by: a. plasma sodium concentration b. plasma calcium concentration c. plasma potassium concentration d. angiotensin II
Last Answer : angiotensin II
Description : Following acute haemorrhage, the following compensatory mechanisms occur: a. increased chemoreceptor discharge b. increased level of circulating angiotensin II c. vasoconstriction of renal efferent arterioles d. all above
Last Answer : all above
Description : Angiotensin II: a. is an octapeptide b. is produced mainly in the lungs c. causes thirst d. all
Last Answer : all
Description : Aliskiren acts by (A) inhibiting the conversion of Angiotensin I to II (B) inhibiting the release of rennin (C) inhibiting the binding of Angiotensin II to the receptor (D) inhibiting the action of aldosterone
Last Answer : (B) inhibiting the release of rennin
Description : Select the nonapeptide which can be generated from plasma globulin by snake venom enzymes, causes fall in BP and intense pain when applied to blister base: A. Kallidin B. Bradykinin C. Angiotensin II D. Angiotensin III
Last Answer : B. Bradykinin
Description : Bradykinin and angiotensin II have the following feature common to both: A. They both cause fall in BP B. They both are degraded by Kininase II C. Their precursor proteins are plasma α2 globulins D. They both release aldosterone from adrenal cortex
Last Answer : C. Their precursor proteins are plasma α2 globulins
Description : Enalapril differs from captopril in that: A. It blocks angiotensin II receptors B. It does not produce cough as a side effect C. It is less liable to cause abrupt first dose hypotension D. It has a shorter duration of action
Last Answer : C. It is less liable to cause abrupt first dose hypotension
Description : Captopril pretreatment: A. Inhibits the pressor action of angiotensin I B. Inhibits the pressor action of angiotensin II C. Potentiates the depressor action of bradykinin D. Both ‘A’ and ‘C’ are correct
Last Answer : D. Both ‘A’ and ‘C’ are correct
Description : Ventricular remodeling after myocardial infarction involves the mediation of: A. Angiotensin II B. Prostaglandin C. Bradykinin D. Thromboxane A2
Last Answer : A. Angiotensin II
Description : Angiotensin II plays a key role in the following risk factor for ischaemic heart disease: A. Hypercholesterolemia B. Ventricular hypertrophy C. Carbohydrate intolerance D. Cardiac arrhythmia
Last Answer : B. Ventricular hypertrophy
Description : Angiotensin III is equipotent to angiotensin II in: A. Releasing aldosterone from adrenal cortex B. Promoting Na+ and water reabsorption by direct intrarenal action C. Causing vasoconstriction D. Contracting intestinal smooth muscle
Last Answer : A. Releasing aldosterone from adrenal cortex
Description : Under physiological conditions the rate limiting enzyme in the generation of angiotensin II is: A. Renin B. Angiotensin converting enzyme C. Aminopeptidase D. Angiotensinase
Last Answer : A. Renin
Description : There are no preformed stores of the following autacoid/autacoids: A. Prostaglandins B. Leukotrienes C. Angiotensin II D. All of the above
Description : Assertion `:-` An increase in glomerular blood pressure can activate the JG of kidney to release renin. Reason `:-` Angiotensin I is a powerful vaso c
Last Answer : Assertion `:-` An increase in glomerular blood pressure can activate the JG of kidney to release renin. ... . D. If both Assertion & Reason are false.
Description : Methyl dopa decreases blood pressure by (A) Inhibiting the synthesis of catecholamines (B) Antagonising the action of aldosterone (C) Stimulating the release of renin (D) Inhibiting the breakdown of angiotensin
Last Answer : Answer : A
Description : Fight-or-flight reactions cause activation of (a) the parathyroid glands, leading to increased metabolic rate (b) the kidney, leading to suppression of renin- angiotensin-aldosterone pathway (c) ... epinephrine and norepinephrine (d) the pancreas leading to a reduction in the blood sugar levels.
Last Answer : (c) the adrenal medulla, leading to increased secretion of epinephrine and norepinephrine
Description : Advantages of angiotensin converting enzyme inhibitors as antihypertensive include the following except: A. They tend to reverse left ventricular hypertrophy B. Their efficacy is not reduced by nonsteroidal ... . They do not worsen blood lipid profile D. They do not impair work performance
Last Answer : B. Their efficacy is not reduced by nonsteroidal antiinflammatory drugs
Description : Read the following points `:-` (i) Increase GFR (ii) Increase B.P. (iii) Decreases blood volume (iv) Increases aldosterone secretion (v) Vasoconstrict
Last Answer : Read the following points `:-` (i) Increase GFR (ii) Increase B.P. (iii) Decreases blood volume (iv) ... II ? A. Two B. Three C. Four D. Five
Description : What is the function of Renin-Angiotensin in the regulation of kidney function? -Biology
Last Answer : answer:
Description : Assertion `:-` Feedback mechanism for regulartion of kidney involve hypothalamus & JGA. Reason `:-` ANF mechanism check renin-angiotensin mechanism.
Last Answer : Assertion `:-` Feedback mechanism for regulartion of kidney involve hypothalamus & JGA. Reason `:-` ANF ... D. If both Assertion & Reason are false.
Description : Secretion of mineralcorticoids is increased by (A) ACTH (B) Angiotensin (C) Hypokalaemia (D) Hypernatraemia
Description : In the synthesis of Angiotensin I, rennin acts on Angiotensinogen and cleaves the (A) Leucine – leucine at 10 and 11 position (B) Valine – tyrosine at 3 and 4 position (C) Isoleucine – histidine at 5 and 6 position (D) Proline – histidine at 7 and 8 position
Description : Which of the following statement(s) is/are true concerning the neuroendocrine responses to shock? a. Sympathetic nerve endings release epinephrine which is responsible for greater than 80% ... injury and sepsis d. The renin-angiotensin axis further augments the sympathetic-mediated vasoconstriction
Last Answer : Answer: c, d The neuroendocrine response to shock attempts to achieve restoration of effective blood volume, mobilization of metabolic substrates, and maintenance of central ... . Angiotensin II is an extremely effective vasoconstrictor that further augments sympathetic-mediated vasoconstriction
Description : Which of the following statements about hypertension in diabetes patients is/are correct? A. Hypertension worsens the macrovascular disease of diabetes patients. B. Hypertension accelerates the ... single-drug therapy, are not indicated in the treatment of hypertension in diabetes patients.
Last Answer : Answer: ABCDE DISCUSSION: All of the answers listed are correct. By damaging endothelial cells, hypertension worsens macrovascular disease in all patients but especially in diabetics. Hypertension ... is not indicated because the chronic state of dehydration in such patients may become worse
Description : Tachyphylaxis to many actions on repeated injection is a feature of the following autocoid (a) Histamine (b) 5-Hydroxytryptamine (c) Bradykinin (d) Angiotensin
Description : Aldosterone release is stimulated by (a) Angiotensin I (b) Angiotensin (c) Angiotensin III (d) Both (b) and (c)
Description : Which hormones do stimulate the production of pancreatic juice and bicarbonate? (a) Angiotensin and epinephrine (b) Gastrin and insulin (c) Cholecystokinin and secretin (d) Insulin and glucagon
Last Answer : (c) Cholecystokinin and secretin
Description : Angiotensin converting enzyme inhibitors are contraindicated in: A. High renin hypertensives B. Diabetics C. Congestive heart failure patients D. Pregnant women
Last Answer : D. Pregnant women
Description : The following type of vasodilator is not beneficial in CHF due to systolic dysfunction: A. Calcium channel blocker B. Angiotensin converting enzyme inhibitor C. Nitrate D. Hydralazine
Last Answer : A. Calcium channel blocker
Description : Choose the drug that selectively blocks AT1 subtype of angiotensin receptors: A. Ramipril B. Lovastatin C. Candesartan D. Sumatriptan
Last Answer : C. Candesartan
Description : Clinically, the angiotensin antagonists share the following features of angiotensin converting enzyme inhibitors except: A. Antihypertensive efficacy B. Potential to reverse left ventricular hypertrophy ... of effect on carbohydrate tolerance D. Potential to induce cough in susceptible individuals
Last Answer : D. Potential to induce cough in susceptible individuals
Description : Which of the following statements most closely describes the current status of angiotensin converting enzyme inhibitors in congestive heart failure: A. They are the first choice drugs unless contraindicated B. ... substitute for digitalis D. They are to be used as adjuncts only in resistant cases
Last Answer : D. They are to be used as adjuncts only in resistant cases
Description : Angiotensin converting enzyme inhibitors afford maximum protection against progression of heart failure when used: A. At the higher therapeutic dose range over long term B. At the maximum tolerated dose only till ... restored C. At low doses over long term D. At low doses along with diuretics/digoxi
Last Answer : A. At the higher therapeutic dose range over long term
Description : Angiotensin converting enzyme inhibitors reduce the following haemodynamic parameters in congestive heart failure except: A. Systemic vascular resistance B. Right atrial pressure C. Cardiac output D. Heart rate × pressure product
Last Answer : C. Cardiac output
Description : Potentiation of bradykinin appears to play a role in the following effects of angiotensin converting enzyme inhibitors except: A. Fall in BP in the short term B. Fall in BP in the long term C. Cough in susceptible individuals D. Angioedema in susceptible individuals
Last Answer : B. Fall in BP in the long term
Description : The following is a pressor peptide that can be generated both in circulation as well as locally in certain tissues: A. Bradykinin B. Angiotensin C. Kallidin D. Plasmin
Last Answer : B. Angiotensin
Description : Sildenafil is contraindicated in patients taking the following class of drugs: A. α-adrenergic blockers B. β-adrenergic blockers C. Organic nitrates D. Angiotensin converting enzyme inhibitors
Last Answer : C. Organic nitrates