The first clinical gene therapy was given in 1990 to a 4 years old with enzyme deficiency of

The first clinical gene therapy was given in 1990 to a 4 years old with enzyme deficiency of
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The first clinical gene therapy was given in 1990 to a 4 years old with enzyme deficiency ... tyrosine oxidase C. monaine oxidase D. monamine oxidase
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Which kind of therapy was given in 1990 to a four- year-old girl with adenosine deaminase (ADA) deficiency? (a) Gene therapy (b) Chemotherapy (c) Immunotherapy (d) Radiation therapy

Description : Which kind of therapy was given in 1990 to a four- year-old girl with adenosine deaminase (ADA) deficiency? (a) Gene therapy (b) Chemotherapy (c) Immunotherapy (d) Radiation therapy

Last Answer : (a) Gene therapy

The first clinical gene therapy was given for treating (a) diabetes mellitus (b) chicken pox (c) rheumatoid arthritis (d) adenosine deaminase deficiency.

Description : The first clinical gene therapy was given for treating (a) diabetes mellitus (b) chicken pox (c) rheumatoid arthritis (d) adenosine deaminase deficiency.

Last Answer : (d) adenosine deaminase deficiency.

Which kind of therapy was given in 1990 to a four year old girl with adenosine deaminase (ADA) deficiency?

Description : Which kind of therapy was given in 1990 to a four year old girl with adenosine deaminase (ADA) deficiency?

Last Answer : Which kind of therapy was given in 1990 to a four year old girl with adenosine deaminase (ADA ... B. radiation therapy C. gene therapy D. chemotherapy

Trials for gene therapy in human beings were first carried out, with considerable success, in a genetic disease called (A) Cystic fibrosis (B) Thalassemia (C) Adenosine deaminase deficiency (D) Lesch-Nyhan syndrome

Description : Trials for gene therapy in human beings were first carried out, with considerable success, in a genetic disease called (A) Cystic fibrosis (B) Thalassemia (C) Adenosine deaminase deficiency (D) Lesch-Nyhan syndrome

Last Answer : Answer : C

Amplification of dihydrofolate reductase gene in a cancer cell makes the cell (A) Susceptible to folic acid deficiency (B) Less malignant (C) Resistant to amethopterin therapy (D) Responsive to amethopterin therapy

Description : Amplification of dihydrofolate reductase gene in a cancer cell makes the cell (A) Susceptible to folic acid deficiency (B) Less malignant (C) Resistant to amethopterin therapy (D) Responsive to amethopterin therapy

Last Answer : Answer : C

Match the following columns and select the correct option. Column-I Column-II (A) Bt cotton (i) Gene therapy (B) Adenosine (ii) Cellular defence deaminase deficiency (C) RNAi (iii) Detection of HIV infection (D) PCR (iv) Bacillus thuringiensis (A) (B) (C) (D) (a) (iv) (i) (ii) (iii) (b) (iii) (ii) (i) (iv) (c) (ii) (iii) (iv) (i) (d) (i) (ii) (iii) (iv)

Description : Match the following columns and select the correct option. Column-I Column-II (A) Bt cotton (i) Gene therapy (B) Adenosine (ii) Cellular defence deaminase deficiency (C) RNAi (iii) Detection of HIV infection (D) PCR (iv) Bacillus ... (i) (iv) (c) (ii) (iii) (iv) (i) (d) (i) (ii) (iii) (iv)

Last Answer : (a) (iv) (i) (ii) (iii)

Which one of the following statements concerning glucose-6-phosphate dehydrogenase deficiency is correct? (A) Young R.B.Cs, particularly reticulocytes, contain the highest enzyme activity cells show less enzyme activity (B) Glucose-6-P Dehydroglucose deficiency leads to disfuction of many tissues (C) G-6-p Dehydroglucose deficiency is due to a single deletion of a large sequence of DNA in the G-6-PD gene (D) G-6-PD deficiency is precipitated by ingestion of drugs such as aspirin

Description : Which one of the following statements concerning glucose-6-phosphate dehydrogenase deficiency is correct? (A) Young R.B.Cs, particularly reticulocytes, contain the highest enzyme activity cells show less enzyme ... PD gene (D) G-6-PD deficiency is precipitated by ingestion of drugs such as aspirin

Last Answer : Answer : A

A specific BRCA1 cancer-predisposing gene mutation seems to occur more frequently among women of which descent? a) Ashkanazi Jewish Expression of the BRCA1 gene is an example of inheritance in the development of breast cancer. b) Mediterranean Glucose-6-phosphate dehydrogenase deficiency (G6PD) is a common enzyme abnormality that affects millions of people throughout the world, especially those of Mediterranean, South East Asian, African, Middle Eastern, and Near Eastern origin.

Description : A specific BRCA1 cancer-predisposing gene mutation seems to occur more frequently among women of which descent? a) Ashkanazi Jewish Expression of the BRCA1 gene is an example of ... of treatment for tuberculosis) are at significantly increased risk for developing isoniazid-induced hepatitis.

Last Answer : a) Ashkanazi Jewish Expression of the BRCA1 gene is an example of inheritance in the development of breast cancer.

The genetic defect–adenosine deaminase (ADA) deficiency may be cured permanently by (a) administering adenosine deaminase activators (b) introducing bone marrow cells producing ADA into cells at early embryonic stages (c) enzyme replacement therapy (d) periodic infusion of genetically engineered lymphocytes having functional ADA cDNA

Description : The genetic defect-adenosine deaminase (ADA) deficiency may be cured permanently by (a) administering adenosine deaminase activators (b) introducing bone marrow cells producing ADA into ... replacement therapy (d) periodic infusion of genetically engineered lymphocytes having functional ADA cDNA

Last Answer : (b) introducing bone marrow cells producing ADA into cells at early embryonic stages

What is the best clinical course of therapy in HIV bone disease?

Description : What is the best clinical course of therapy in HIV bone disease?

Last Answer : Feel Free to Answer

Which of the following statement(s) is/are true concerning the treatment of MOFS? a. Prevention and therapy of MOFS requires control of the infectious or inflammatory source b. Restoration of normal clinical parameters such as blood pressure, pulse rate, and urine output ensures optimal resuscitation in most patients c. Branch chain amino acids play and important role in the nutritional support of the patient d. Because of the nature of gut injury, total parenteral nutrition is preferred for most patients with MOFS

Description : Which of the following statement(s) is/are true concerning the treatment of MOFS? a. Prevention and therapy of MOFS requires control of the infectious or inflammatory source b. Restoration of normal ... of the nature of gut injury, total parenteral nutrition is preferred for most patients with MOFS

Last Answer : Answer: a, c The therapy of MOFS is directed towards interrupting the involving pathophysiologic process and providing an optimal physiologic environment for healing and recovery. ... Enteral absorption and processing of nutrients appears superior to TPN and lessens overall complications

The use of antibiotics can be based on either the clinical course of a patient without the benefit of well-defined microbiologic data (empiric therapy), or targeted at specific identified pathogens once sensitivity reports are available (directed therapy). The following statement(s) is/are true concerning these therapies. a. The issue of toxic side effects of antibiotics is only important in dealing with emperic therapy b. Single agent therapy is generally inferior to specific multi-drug therapy (aminoglycoside plus an antianaerobic agent) for the treatment of secondary bacterial peritonitis due to appendicitis, diverticulitis, penetrating gastrointestinal injury, or anastomotic leak c. With the empiric use of antibiotics, a diligent search for the septic source should be undertaken and co

Description : The use of antibiotics can be based on either the clinical course of a patient without the benefit of well-defined microbiologic data (empiric therapy), or targeted at ... which polymicrobial infection is identified, specifically-directed treatment for the predominant organism is satisfactory

Last Answer : Answer: c The use of empiric therapy without the benefit of well-defined microbiologic data is appropriate when there is sufficient clinical evidence to support the diagnosis such that it would ... components of the infection if the body site is such that these microorganisms may be present

When caring for a patient with an uncomplicated, mild urinary tract infection (UTI), the nurse knows that recent studies have shown which of the following drugs to be a good choice for shortcourse (e.g. 3-day) therapy? a) Levofloxacin (Levaquin) Levofloxacin, a floroquinolone, is a good choice for short-course therapy of uncomplicated, mild to moderate UTI. Clinical trial data show high patient compliance with the 3-day regimen (95.6%) and a high eradication rate for all pathogens (96.4%).

Description : When caring for a patient with an uncomplicated, mild urinary tract infection (UTI), the nurse knows that recent studies have shown which of the following drugs to be a good choice for ... to be significantly more effective than TMP-SMX in community-based patients and in nursing home residents.

Last Answer : a) Levofloxacin (Levaquin) Levofloxacin, a floroquinolone, is a good choice for short-course therapy of uncomplicated, mild to moderate UTI. Clinical trial data show high patient compliance with the 3-day regimen (95.6%) and a high eradication rate for all pathogens (96.4%).

Who was the first patient who was given gene therapy? -Biology

Description : Who was the first patient who was given gene therapy? -Biology

Last Answer : answer:

What is the clinical significance of transketolase enzyme?

Description : What is the clinical significance of transketolase enzyme?

Last Answer : The transketolase reaction is measured in RBCs as an index of the thiamine status of an individual.

In 1990, a person is 15 years old. In 1995 that same person is 10 years old. How is this possible? -Riddles

Description : In 1990, a person is 15 years old. In 1995 that same person is 10 years old. How is this possible? -Riddles

Last Answer : The years are in B.C.

What is gene therapy?

Description : What is gene therapy?

Last Answer : Gene therapy is a type of medical treatment that involves the modification of a person's genetic material in order to treat or prevent disease, and is an active area of research with potential applications in a wide range of medical conditions.

What is gene therapy?

Description : What is gene therapy?

Last Answer : A: Gene therapy is a medical treatment that involves altering the genetic material of an individual's cells in order to treat or prevent disease.

Where can I find peer-reviewed articles on the corporate social responsibility of gene therapy companies?

Description : Where can I find peer-reviewed articles on the corporate social responsibility of gene therapy companies?

Last Answer : answer:The best peer-reviewed articles are not going to be found freely online. If you are in college you might do well to check to see if your school subscribes to services like JSTOR or ... some large academic databases as well. Typically the kind of stuff you would otherwise have to pay for.

What is gene therapy? -Biology

Description : What is gene therapy? -Biology

Last Answer : answer:

Define gene therapy -Biology

Description : Define gene therapy -Biology

Last Answer : answer:

What is somatic gene therapy? -Biology

Description : What is somatic gene therapy? -Biology

Last Answer : answer:

What is germ line gene therapy? -Biology

Description : What is germ line gene therapy? -Biology

Last Answer : answer:

Limitations of gene therapy? -Biology

Description : Limitations of gene therapy? -Biology

Last Answer : answer:

Define gene therapy -Biology

Description : Define gene therapy -Biology

Last Answer : answer:

What is somatic gene therapy? -Biology

Description : What is somatic gene therapy? -Biology

Last Answer : answer:

What is germ line gene therapy? -Biology

Description : What is germ line gene therapy? -Biology

Last Answer : answer:

Limitations of gene therapy? -Biology

Description : Limitations of gene therapy? -Biology

Last Answer : answer:

How Many Types of Gene Therapy ?

Description : How Many Types of Gene Therapy ?

Last Answer : 2 types of gene therapy. Namely: 1. Germ-line therapy ; 2. Somatic cell therapy

What is Gene Therapy ?

Description : What is Gene Therapy ?

Last Answer : Gene therapy is the process of replacing healthy genes by removing harmful genes. Gene therapy is given to treat some serious diseases such as cancer , heart disease , diabetes , hemophilia and AIDS.

What is gene therapy ?

Description : What is gene therapy ?

Last Answer : - Gene therapy is a healthy gene replacement by removing harmful genes from the organism.

An example of gene therapy is

Description : An example of gene therapy is

Last Answer : An example of gene therapy is A. bt cotton B. flavr savr tomato C. pusa swarnim D. goden rice

An example of gene therapy is

Description : An example of gene therapy is

Last Answer : An example of gene therapy is A. production of injectable hepatitis b vaccine B. ... artificaila inseina tion and implanatation of fertilezed eggs

Consider the following methods by which gene therapy can be performed: 1. By introducing a new gene into the body 2. By the use of stem cells 3. By delivery of genes using gold nanoparticles The correct methods could be: (a) 1 and 2 only (b) 1 and 3 only (c) 2 and 3 only (d) 1, 2 and 3 only

Description : Consider the following methods by which gene therapy can be performed: 1. By introducing a new gene into the body 2. By the use of stem cells 3. By delivery of genes using gold nanoparticles The correct methods could be: (a) 1 and 2 only (b) 1 and 3 only (c) 2 and 3 only (d) 1, 2 and 3 only

Last Answer : Ans:(a)

Which one of the following vectors is used to replace the defective gene in gene therapy? (a) Adenovirus (b) Cosmid (c) Ri plasmid (d) Ti plasmid

Description : Which one of the following vectors is used to replace the defective gene in gene therapy? (a) Adenovirus (b) Cosmid (c) Ri plasmid (d) Ti plasmid

Last Answer : (a) Adenovirus

Briefly describe gene therapy

Description : Briefly describe gene therapy

Last Answer : It is an advanced biotechnological technique which is used to cure genetic and acquired diseases like cancer and AIDS. In the process, defective genes are supplemented or replaced by normal genes.

Amplification of dihydrofolate reductase gene may be brought about by (A) High concentrations of folic acid (B) Deficiency of folic acid (C) Low concentration of thymidylate (D) Amethopterin

Description : Amplification of dihydrofolate reductase gene may be brought about by (A) High concentrations of folic acid (B) Deficiency of folic acid (C) Low concentration of thymidylate (D) Amethopterin

Last Answer : Answer : D

Ehlers-Danlos syndrome characterized by hypermobile joints and skin abnormalities is due to (A) Abnormality in gene for procollagen (B) Deficiency of lysyl oxidase (C) Deficiency of prolyl hydroxylase (D) Deficiency of lysyl hydroxylase

Description : Ehlers-Danlos syndrome characterized by hypermobile joints and skin abnormalities is due to (A) Abnormality in gene for procollagen (B) Deficiency of lysyl oxidase (C) Deficiency of prolyl hydroxylase (D) Deficiency of lysyl hydroxylase

Last Answer : Answer : A

Is there any research indicating that light therapy lamps help with vitamin D deficiency?

Description : Is there any research indicating that light therapy lamps help with vitamin D deficiency?

Last Answer : answer:The body produces Vitamin D from exposure to Ultraviolet rays, the problem is skin cancer. Instead take D3 capsules or other D supplements.

Which of the following is true? Hypochromic anaemia is not due to iron deficiency except (A) Serum ‘Fe’ is high (B) Normal/low transferrin (C) Stainable iron in bone marrow (D) Iron therapy is affective

Description : Which of the following is true? Hypochromic anaemia is not due to iron deficiency except (A) Serum ‘Fe’ is high (B) Normal/low transferrin (C) Stainable iron in bone marrow (D) Iron therapy is affective

Last Answer : Answer : D

Vitamin B6 deficiency may occur during therapy with (A) Isoniazid (B) Terramycin (C) Sulpha drugs (D) Aspirin

Description : Vitamin B6 deficiency may occur during therapy with (A) Isoniazid (B) Terramycin (C) Sulpha drugs (D) Aspirin

Last Answer : Answer : A

All the following conditions produce a real or functional deficiency of vitamin K except (A) Prolonged oral, broad spectrum antibiotic therapy (B) Total lack of red meat in the diet (C) The total lack of green leafy vegetables in the diet (D) Being a new born infant

Description : All the following conditions produce a real or functional deficiency of vitamin K except (A) Prolonged oral, broad spectrum antibiotic therapy (B) Total lack of red meat in the diet (C) The total lack of green leafy vegetables in the diet (D) Being a new born infant

Last Answer : Answer : B

The standard management oral anticoagulant therapy for chronic treatment of venous thromboembolism is with the drug warfarin. Which of the following statement(s) is/are true concerning the administration of warfarin? a. An important complication of warfarin therapy is skin necrosis in patients with protein C deficiency b. Warfarin interferes with vitamin K dependent clotting factors II, VII, IX, X c. For effective anticoagulation the prothrombin time (PT) should be kept at 2 control d. It is recommended that warfarin be continued for at least one year after initial episode of deep venous thrombosis

Description : The standard management oral anticoagulant therapy for chronic treatment of venous thromboembolism is with the drug warfarin. Which of the following statement(s) is/are true concerning the administration ... warfarin be continued for at least one year after initial episode of deep venous thrombosis

Last Answer : Answer: a, b Warfarin interferes with the vitamin K dependent clotting factors II, VII, IX and X, protein C, and protein S. An important complication of warfarin is skin ... the benefit from anticoagulant therapy and thus is the basis for discontinuing warfarin administration at this time

The transfusion of fresh frozen plasma (FFP) is indicated for which of the following reasons? A. Volume replacement. B. As a nutritional supplement. C. Specific coagulation factor deficiency with an abnormal prothrombin time (PT) and/or an abnormal activated partial thromboplastin time (APTT). D. For the correction of abnormal PT secondary to warfarin therapy, vitamin K deficiency, or liver disease.

Description : The transfusion of fresh frozen plasma (FFP) is indicated for which of the following reasons? A. Volume replacement. B. As a nutritional supplement. C. Specific coagulation factor deficiency ... the correction of abnormal PT secondary to warfarin therapy, vitamin K deficiency, or liver disease.

Last Answer : Answer: CD DISCUSSION: The use of FFP as a volume expander is not indicated. There are currently several preparations (both crystalloid and colloid) that are equally effective and do not carry the infectious and ... vitamin K-dependent factors II, VII, IX, and X, as well as protein C and protein S

A patient of megaloblastic anaemia was treated with oral folic acid 5 mg daily. After 2 weeks he reported back with cognitive deficit, sensory disturbance, depressed knee jerk, while blood picture and haemoglobin level were improved. What could be the most likely explanation: A. Folic acid was not adequately absorbed resulting in partial response B. Folate therapy has precipitated vitamin B12 deficiency in the neural tissue C. Folate therapy has unmasked pyridoxine deficiency D. Patient has folate reductase abnormality in the nervous system

Description : A patient of megaloblastic anaemia was treated with oral folic acid 5 mg daily. After 2 weeks he reported back with cognitive deficit, sensory disturbance, depressed knee jerk, while ... therapy has unmasked pyridoxine deficiency D. Patient has folate reductase abnormality in the nervous system

Last Answer : D. Patient has folate reductase abnormality in the nervous system

Megaloblastic anaemia developing under the following condition is due entirely to folate deficiency not associated with vitamin B12 deficiency: A. Malnutrition B. Blind loop syndrome C. Phenytoin therapy D. Pregnancy

Description : Megaloblastic anaemia developing under the following condition is due entirely to folate deficiency not associated with vitamin B12 deficiency: A. Malnutrition B. Blind loop syndrome C. Phenytoin therapy D. Pregnancy

Last Answer : C. Phenytoin therapy

A patient of iron deficiency anaemia has been put on iron therapy. What should be the rate of rise in haemoglobin level of blood so that response is considered adequate: A. 0.05 – 0.1 g% per week B. 0.1 – 0.2 g% per week C. 0.5 – 1.0 g% per week D. More than 1.0 g% per week

Description : A patient of iron deficiency anaemia has been put on iron therapy. What should be the rate of rise in haemoglobin level of blood so that response is considered adequate: A. 0.05 – 0.1 g% per week B. 0.1 – 0.2 g% per week C. 0.5 – 1.0 g% per week D. More than 1.0 g% per week

Last Answer : C. 0.5 – 1.0 g% per week

An important step in protein synthesis is transcription. Which of the following statement(s) is/are true concerning this process? a. The first step in gene transcription involves separating the double helix of DNA by an enzyme known as DNA polymerase b. The initial product of DNA transcription is called heterogeneous nuclear RNA which codes directly for proteins c. After processing is complete, the mRNA is exported from the nucleus to the cytoplasm d. Only one protein can be produced from an initial mRNA strand

Description : An important step in protein synthesis is transcription. Which of the following statement(s) is/are true concerning this process? a. The first step in gene transcription involves separating the double helix ... nucleus to the cytoplasm d. Only one protein can be produced from an initial mRNA strand

Last Answer : Answer: c Transcription of a gene begins at an initiation site associated with a specific DNA sequence, termed a promoter region. After binding to DNA, the RNA polymerase opens up a short ... different proteins from the same gene. mRNA is exported from the nucleus only after processing is complete

One gene one enzyme theory was proposed by

Description : One gene one enzyme theory was proposed by

Last Answer : One gene one enzyme theory was proposed by A. Khorana and Nirenberg B. Beadle and Tatum C. Bateson and Punnet D. Bridges