What are NDDS? Differentiate between sustained and controlled release dosage forms.

What are NDDS? Differentiate between sustained and controlled release dosage forms.
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1 Answer

Answer :

NDDS: 

New drug delivery system delivers or aimed at maximizing the drug effectiveness or minimizing the side effects. Some of the Novel dosage forms are:

1) Implants

2) Controlled drug delivery system

3) Sustained release system

4) Liposomes

5) Erythrocytes

6) Nanoparticles

7) Prodrugs

8) Film and strips.

Difference between Sustained and Controlled release dosage form: 

Sr.No.
Sustained Release Controlled Release
1 Onset of action is slow and duration of action is less.
Onset of action is fast and longer duration of action.
2 Frequency of dosing is more
Frequency of dosing is less.
3 Dose concentration in plasma is not maintained.
Therapeutically effective and constant concentration of the drug in the plasma is maintained.
4 The rate of release is not at predetermined rate.
The rate of release at predetermined rate.
5 It prolongs the release of drug.
It controls the release of drug.
6 e.g. sustain release tables.
e.g. Transdermal patches. 
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