Mention different types of closures. Comment on materials used for making closures.

Mention different types of closures. Comment on materials used for making closures.
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1 Answer

Answer :

Types of closures with examples: 

1. Plug type.

2. Crown cap.

3. Push-fit cap.

4. Screw closures.

Materials used in pharmaceutical closures:  

1) Rubber

 Cork is obtained from the bark of oak tree.

 Cork is chemically inert and it does not impart any odour or flavour to the product.

 Not used for liquid preparations because of danger of mould growth

 Cork closures are rarely used nowadays & replaced by plastic or rubber closures.

2) Glass

 Glass closures are ideal but they mostly slip during transportation and handling.

 Mainly used for reagent bottles in laboratories.

3)Plastic

 Plastic closures are nowadays commonly used

 They are available in various shapes and sizes.

 They are light in weight and are unbreakable.

 Plastic closures must be tested for any extractable matter ,physiochemical & biological testing

4)Metal

 Made from tin plate and aluminium.

 Aluminium closures are preferred because of their durability and also ease of conversion into desired shape.

 Metal closures can be made pilfer-proof by using a liner.

5)Rubber

 Rubber is used mainly for the construction of closure meant for vials, transfusion fluid bottles.

 Rubber, two types natural or synthetic, 
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