Describe the stages of percolations

Describe the stages of percolations 
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1 Answer

Answer :

a. Imbibition:

 Drug is kept is moistened with sufficient quantity of menstruum.

 Allow to stand for 4 hr.

Significance:

i. It allow the swelling of tissue of drug before packing.

ii. It is imbibed for uniform packing in percolator.

iii. It allows the entrapped air to escape.

iv. Quantity of menstrum required can be reduced.

b.Maceration:

 The moistened drug is left in contact with menstruum for 24 hrs.

 During this period, menstruum dissolves the active constituents of the drug.

c.Percolation:

 It consists of downward displacement of the saturated menstrum formed in maceration and extraction.

 After collecting 3/4th volume of product then marc is pressed.

 Mix the liquids.
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