Aspirin reduces fever by: A. Decreasing heat production in the body B. Enhancing cutaneous blood flow C. Inducing sweating D. Both ‘B’ and ‘C’ are correct

Aspirin reduces fever by: A. Decreasing heat production in the body B. Enhancing cutaneous blood flow C. Inducing sweating D. Both ‘B’ and ‘C’ are correct  
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D. Both ‘B’ and ‘C’ are correct 
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Aspirin reduces fever by (a) Decreasing heat production in the body (b) Enhancing cutaneous blood flow (c) Inducing sweating (d) Both (b) and (c)

Description : Aspirin reduces fever by (a) Decreasing heat production in the body (b) Enhancing cutaneous blood flow (c) Inducing sweating (d) Both (b) and (c)

Last Answer : Ans: D

Pilocarpine reduces intraocular tension in open angle glaucoma by: A. Contracting sphincter pupillae B. Increasing tone of ciliary muscle C. Reducing aqueous formation D. Enhancing uveo-scleral outflow

Description : Pilocarpine reduces intraocular tension in open angle glaucoma by: A. Contracting sphincter pupillae B. Increasing tone of ciliary muscle C. Reducing aqueous formation D. Enhancing uveo-scleral outflow

Last Answer : B. Increasing tone of ciliary muscle

Blood flow in the following vascular bed generally decreases under the influence of glyceryl trinitrate: A. Coronary B. Cutaneous C. Renal D. Cranial

Description : Blood flow in the following vascular bed generally decreases under the influence of glyceryl trinitrate: A. Coronary B. Cutaneous C. Renal D. Cranial

Last Answer : C. Renal

Choose the correct statement about aspirin: A. In an afebrile patient acute overdose of aspirin produces hypothermia B. Aspirin suppresses flushing attending large dose of nicotinic acid C. Aspirin therapy prevents granulomatous lesions and cardiac complications of acute rheumatic fever D. Long term aspirin therapy increases the risk of developing colon cancer

Description : Choose the correct statement about aspirin: A. In an afebrile patient acute overdose of aspirin produces hypothermia B. Aspirin suppresses flushing attending large dose of nicotinic acid C. Aspirin ... acute rheumatic fever D. Long term aspirin therapy increases the risk of developing colon cancer

Last Answer : B. Aspirin suppresses flushing attending large dose of nicotinic acid

The following drug reduces the effect of oral anticoagulants: A. Broad spectrum antibiotic B. Cimetidine C. Aspirin D. Oral contraceptive

Description : The following drug reduces the effect of oral anticoagulants: A. Broad spectrum antibiotic B. Cimetidine C. Aspirin D. Oral contraceptive

Last Answer : D. Oral contraceptive

Which of the following constitutes ‘drug abuse’: A. Physician prescribed use of penicillin G for the cure of viral fever B. Self administration of aspirin to relieve headache C. Repeated self administration of morphine to derive euphoria D. All of the above

Description : Which of the following constitutes ‘drug abuse’: A. Physician prescribed use of penicillin G for the cure of viral fever B. Self administration of aspirin to relieve headache C. Repeated self administration of morphine to derive euphoria D. All of the above

Last Answer : C. Repeated self administration of morphine to derive euphoria

The primary mechanism of action of the combined estrogen-progestin oral contraceptive pill is: A. Production of cervical mucus hostile to sperm penetration B. Suppression of FSH and LH release C. Making endometrium unsuitable for implantation D. Enhancing uterine contractions to dislodge the fertilized ovum

Description : The primary mechanism of action of the combined estrogen-progestin oral contraceptive pill is: A. Production of cervical mucus hostile to sperm penetration B. Suppression of FSH and ... Making endometrium unsuitable for implantation D. Enhancing uterine contractions to dislodge the fertilized ovum

Last Answer : B. Suppression of FSH and LH release

Anticancer drugs weaken host defence by: A. Damaging respiratory and gut epithelia B. Inducing granulocytopenia C. Altering resident microbial flora D. Both 'A' and 'B' are correct

Description : Anticancer drugs weaken host defence by: A. Damaging respiratory and gut epithelia B. Inducing granulocytopenia C. Altering resident microbial flora D. Both 'A' and 'B' are correct

Last Answer : D. Both 'A' and 'B' are correct

Menadione (vitamin K3) can produce kernicterus in neonates by: A. Inducing haemolysis B. Inhibiting glucuronidation of bilirubin C. Displacing plasma protein bound bilirubin D. Both ‘A’ and ‘B’ are correct

Description : Menadione (vitamin K3) can produce kernicterus in neonates by: A. Inducing haemolysis B. Inhibiting glucuronidation of bilirubin C. Displacing plasma protein bound bilirubin D. Both ‘A’ and ‘B’ are correct

Last Answer : D. Both ‘A’ and ‘B’ are correct

Sucralfate promotes healing of duodenal ulcer by: A. Enhancing gastric mucus and bicarbonate secretion B. Coating the ulcer and preventing the action of acid-pepsin on ulcer base C. Promoting regeneration of mucosa D. Both ‘A’ and ‘B’ are correct

Description : Sucralfate promotes healing of duodenal ulcer by: A. Enhancing gastric mucus and bicarbonate secretion B. Coating the ulcer and preventing the action of acid-pepsin on ulcer base C. Promoting regeneration of mucosa D. Both ‘A’ and ‘B’ are correct

Last Answer : B. Coating the ulcer and preventing the action of acid-pepsin on ulcer base

The following is true about actions of ethylalcohol: A. It exerts anticonvulsant action followed by lowering of seizure threshold B. It lowers pain threshold C. It increases confidence and reduces number of errors D. It increases heat production and helps to keep warm in cold weather

Description : The following is true about actions of ethylalcohol: A. It exerts anticonvulsant action followed by lowering of seizure threshold B. It lowers pain threshold C. It increases confidence and reduces number of errors D. It increases heat production and helps to keep warm in cold weather

Last Answer : A. It exerts anticonvulsant action followed by lowering of seizure threshold

In patients with benign prostatic hypertrophy, finasteride exerts the following action/actions: A. Reduces size of the prostate gland B. Increases peak urinary flow rate C. Relaxes vesical sphincter D. Both 'A' and 'B' are correct

Description : In patients with benign prostatic hypertrophy, finasteride exerts the following action/actions: A. Reduces size of the prostate gland B. Increases peak urinary flow rate C. Relaxes vesical sphincter D. Both 'A' and 'B' are correct

Last Answer : D. Both 'A' and 'B' are correct

Adrenaline raises blood glucose level by the following actions except: A. Inducing hepatic glycogenolysis B. Inhibiting insulin secretion from pancreatic β cells C. Augmenting glucagon secretion from pancreatic α cells D. Inhibiting peripheral glucose utilization

Description : Adrenaline raises blood glucose level by the following actions except: A. Inducing hepatic glycogenolysis B. Inhibiting insulin secretion from pancreatic β cells C. Augmenting glucagon secretion from pancreatic α cells D. Inhibiting peripheral glucose utilization

Last Answer : D. Inhibiting peripheral glucose utilization

Adrenaline raises blood glucose level by the following actions except: A. Inducing hepatic glycogenolysis B. Inhibiting insulin secretion from pancreatic β cells C. Augmenting glucagon secretion from pancreatic α cells D. Inhibiting peripheral glucose utilization

Description : Adrenaline raises blood glucose level by the following actions except: A. Inducing hepatic glycogenolysis B. Inhibiting insulin secretion from pancreatic β cells C. Augmenting glucagon secretion from pancreatic α cells D. Inhibiting peripheral glucose utilization

Last Answer : D. Inhibiting peripheral glucose utilization

What is true of nicotinic acid as well as nicotinamide: A. Both possess vitamin B3 activity B. Both cause cutaneous vasodilatation C. Both lower plasma triglyceride and VLDL levels D. Both cause hyperglycaemia after prolonged medication

Description : What is true of nicotinic acid as well as nicotinamide: A. Both possess vitamin B3 activity B. Both cause cutaneous vasodilatation C. Both lower plasma triglyceride and VLDL levels D. Both cause hyperglycaemia after prolonged medication

Last Answer : A. Both possess vitamin B3 activity

Chloramphenicol inhibits bacterial protein synthesis by: A. Binding to 30S ribosome and inhibiting attachment of aminoacyl tRNA B. Binding to 50S ribosome and preventing peptide bond formation C. Binding to 50S ribosome and blocking translocation of peptide chain D. Binding to both 30S and 50S ribosome and inducing misreading of mRNA code

Description : Chloramphenicol inhibits bacterial protein synthesis by: A. Binding to 30S ribosome and inhibiting attachment of aminoacyl tRNA B. Binding to 50S ribosome and preventing peptide bond formation C. Binding to ... chain D. Binding to both 30S and 50S ribosome and inducing misreading of mRNA code

Last Answer : B. Binding to 50S ribosome and preventing peptide bond formation

Metabolic effects that generally attend antiinflammatory doses of aspirin include the following except: A. Increased CO2 production B. Hepatic glycogen depletion C. Metabolic acidosis D. Compensated respiratory alkalosis

Description : Metabolic effects that generally attend antiinflammatory doses of aspirin include the following except: A. Increased CO2 production B. Hepatic glycogen depletion C. Metabolic acidosis D. Compensated respiratory alkalosis

Last Answer : C. Metabolic acidosis

Occurrence of the following adverse reaction absolutely contraindicates further use of rifampin in the treatment of tuberculosis: A. Respiratory syndrome B. Cutaneous syndrome C. Flu syndrome D. Abdominal syndrome

Description : Occurrence of the following adverse reaction absolutely contraindicates further use of rifampin in the treatment of tuberculosis: A. Respiratory syndrome B. Cutaneous syndrome C. Flu syndrome D. Abdominal syndrome

Last Answer : A. Respiratory syndrome

The following vascular bed is constricted by caffeine: A. Coronary B. Cutaneous C. Cranial D. Mesenteric

Description : The following vascular bed is constricted by caffeine: A. Coronary B. Cutaneous C. Cranial D. Mesenteric

Last Answer : C. Cranial

Morphine analgesia differs from that produced by aspirin in the following respect(s): A. It has a higher ceiling B. It covers both perception as well as psychic processing of the pain C. Visceral and ischaemic pain is relieved better than somatic inflammatory pain D. All of the above are correct

Description : Morphine analgesia differs from that produced by aspirin in the following respect(s): A. It has a higher ceiling B. It covers both perception as well as psychic processing of the pain C. Visceral and ischaemic pain is relieved better than somatic inflammatory pain D. All of the above are correct

Last Answer : D. All of the above are correct

Alkylating agents exert cytotoxic action by inducing: A. Breakage of DNA strand B. Cross linking of DNA strands C. Abnormal pairing of purine and pyrimidine bases D. All of the above

Description : Alkylating agents exert cytotoxic action by inducing: A. Breakage of DNA strand B. Cross linking of DNA strands C. Abnormal pairing of purine and pyrimidine bases D. All of the above

Last Answer : D. All of the above

Aldosterone increases Na+ reabsorption and K+ excretion in the renal collecting duct cells by: A. Inducing synthesis of Na+K+ATPase B. Inducing synthesis of amiloride sensitive Na+ channels C. Translocating Na+ channels from cytosolic site to luminal membrane D. All of the above

Description : Aldosterone increases Na+ reabsorption and K+ excretion in the renal collecting duct cells by: A. Inducing synthesis of Na+K+ATPase B. Inducing synthesis of amiloride sensitive Na+ channels C. Translocating Na+ channels from cytosolic site to luminal membrane D. All of the above

Last Answer : D. All of the above

Ergometrine stops postpartum haemorrhage by: A. Causing vasoconstriction of uterine arteries B. Increasing tone of uterine muscle C. Promoting coagulation D. Inducing platelet aggregation

Description : Ergometrine stops postpartum haemorrhage by: A. Causing vasoconstriction of uterine arteries B. Increasing tone of uterine muscle C. Promoting coagulation D. Inducing platelet aggregation

Last Answer : B. Increasing tone of uterine muscle

The following is an orally active ovulation inducing agent: A. Menotropin B. Mifepristone C. Danazol D. Clomiphene citrate

Description : The following is an orally active ovulation inducing agent: A. Menotropin B. Mifepristone C. Danazol D. Clomiphene citrate

Last Answer : D. Clomiphene citrate

Aldosterone enhances Na+ reabsorption in renal tubules by: A. Stimulating carbonic anhydrase B. Activating Na+ K+ ATPase C. Inducing the synthesis of Na+ K+ ATPase D. Inducing renal prostaglandin synthesis

Description : Aldosterone enhances Na+ reabsorption in renal tubules by: A. Stimulating carbonic anhydrase B. Activating Na+ K+ ATPase C. Inducing the synthesis of Na+ K+ ATPase D. Inducing renal prostaglandin synthesis

Last Answer : C. Inducing the synthesis of Na+ K+ ATPase

Sustained/controlled release oral dosage form is appropriate for the following type of drug: A. An antiarthritic with a plasma half life of 24 hr B. A sleep inducing hypnotic with a plasma half life of 2 hours C. An antihypertensive with a plasma half life of 3 hours D. An analgesic with a plasma half life of 6 hours used for relief of casual headache

Description : Sustained/controlled release oral dosage form is appropriate for the following type of drug: A. An antiarthritic with a plasma half life of 24 hr B. A sleep inducing hypnotic with a plasma half life of ... 3 hours D. An analgesic with a plasma half life of 6 hours used for relief of casual headache

Last Answer : C. An antihypertensive with a plasma half life of 3 hours

Nonsteroidal antiinflammatory drugs reduce the diuretic action of furosemide by: A. Preventing prostaglandin mediated intrarenal haemodynamic actions B. Blocking the action in ascending limb of loop of Henle. C. Enhancing salt and water reabsorption in distal tubule D. Increasing aldosterone secretion

Description : Nonsteroidal antiinflammatory drugs reduce the diuretic action of furosemide by: A. Preventing prostaglandin mediated intrarenal haemodynamic actions B. Blocking the action in ascending limb of loop ... C. Enhancing salt and water reabsorption in distal tubule D. Increasing aldosterone secretion

Last Answer : A. Preventing prostaglandin mediated intrarenal haemodynamic actions

Raised plasma aldosterone level in CHF contributes to disease progression by exerting the following effects except: A. Fibrotic remodeling of myocardium B. Hyperkalemia and hypermagnesemia C. Increasing cardiac preload by Na+ and water retention D. Enhancing cardiotoxicity of sympathetic overactivity

Description : Raised plasma aldosterone level in CHF contributes to disease progression by exerting the following effects except: A. Fibrotic remodeling of myocardium B. Hyperkalemia and hypermagnesemia C. ... cardiac preload by Na+ and water retention D. Enhancing cardiotoxicity of sympathetic overactivity

Last Answer : B. Hyperkalemia and hypermagnesemia

Pyritinol (pyrithioxine) is used as: A. Analeptic drug B. Cognition enhancing drug C. Antiepileptic drug

Description : Pyritinol (pyrithioxine) is used as: A. Analeptic drug B. Cognition enhancing drug C. Antiepileptic drug

Last Answer : B. Cognition enhancing dru

Gabapentin acts: A. As GABAA agonist B. As precursor of GABA C. By enhancing GABA release D. By GABA independent mechanism

Description : Gabapentin acts: A. As GABAA agonist B. As precursor of GABA C. By enhancing GABA release D. By GABA independent mechanism

Last Answer : C. By enhancing GABA release

Timolol eye drops are preferred over pilocarpine eye drops by glaucoma patients because: A. Timolol is more effective than pilocarpine B. Timolol acts by enhancing uveo-scleral outflow C. Timolol produces less ocular side effects D. There are no contraindications to timolol

Description : Timolol eye drops are preferred over pilocarpine eye drops by glaucoma patients because: A. Timolol is more effective than pilocarpine B. Timolol acts by enhancing uveo-scleral outflow C. Timolol produces less ocular side effects D. There are no contraindications to timolol

Last Answer : C. Timolol produces less ocular side effects

Pilocarpine reduces intraocular tension in open angle glaucoma by: A. Contracting sphincter pupillae B. Increasing tone of ciliary muscle C. Reducing aqueous formation D. Enhancing uveo-scleral outflow

Description : Pilocarpine reduces intraocular tension in open angle glaucoma by: A. Contracting sphincter pupillae B. Increasing tone of ciliary muscle C. Reducing aqueous formation D. Enhancing uveo-scleral outflow

Last Answer : B. Increasing tone of ciliary muscle

Which of the following is seen at low (analgesic) doses of aspirin: A. Respiratory stimulation B. Increased occult blood loss in stools C. Increased cardiac output D. Hyperglycaemia

Description :  Which of the following is seen at low (analgesic) doses of aspirin: A. Respiratory stimulation B. Increased occult blood loss in stools C. Increased cardiac output D. Hyperglycaemia

Last Answer : B. Increased occult blood loss in stools

Which of the following property of prostaglandins has been utilized by chinicians in hospital for (A) Inducing fever (B) Causing inflammation (C) Effecting smooth muscle contraction (D) Disaggregation of spermatozoa

Description : Which of the following property of prostaglandins has been utilized by chinicians in hospital for (A) Inducing fever (B) Causing inflammation (C) Effecting smooth muscle contraction (D) Disaggregation of spermatozoa

Last Answer : Answer : C

Inhibition of thromboxane synthesis by aspirin in platelets lasts for 5-7 days because: A. Aspirin persists in the body for 5-7 days B. Aspirin induced depletion of arachidonic acid lasts 5-7 days C. Regeneration of aspirin inhibited cyclooxygenase takes 5-7 days D. Platelets cannot generate fresh thromboxane synthetase and their turnover time is 5-7 days

Description : Inhibition of thromboxane synthesis by aspirin in platelets lasts for 5-7 days because: A. Aspirin persists in the body for 5-7 days B. Aspirin induced depletion of arachidonic acid lasts 5-7 ... 5-7 days D. Platelets cannot generate fresh thromboxane synthetase and their turnover time is 5-7 days

Last Answer : D. Platelets cannot generate fresh thromboxane synthetase and their turnover time is 5-7 days

Choose the correct statement about paracetamol: A. It increases uric acid excretion B. It is the most common drug implicated in causing analgesic nephropathy C. In equianalgesic doses it is safer than aspirin D. It stimulates cellular metabolism

Description : Choose the correct statement about paracetamol: A. It increases uric acid excretion B. It is the most common drug implicated in causing analgesic nephropathy C. In equianalgesic doses it is safer than aspirin D. It stimulates cellular metabolism

Last Answer : C. In equianalgesic doses it is safer than aspirin

Organic nitrates relax vascular smooth muscle by: A. Increasing intracellular cyclic GMP B. Increasing intracellular cyclic AMP C. Decreasing intracellular cyclic AMP D. Both ‘A’ and ‘C’ are correct

Description : Organic nitrates relax vascular smooth muscle by: A. Increasing intracellular cyclic GMP B. Increasing intracellular cyclic AMP C. Decreasing intracellular cyclic AMP D. Both ‘A’ and ‘C’ are correct

Last Answer : A. Increasing intracellular cyclic GMP

Addition of pyrazinamide and ethambutol for the first two months to the isoniazid + rifampin therapy of tuberculosis serves the following purpose(s): A. Reduces the total duration of therapy to 6 months B. Produces more rapid sputum conversion C. Permits reduction of rifampin dose D. Both ‘A’ and ‘B’ are correct

Description : Addition of pyrazinamide and ethambutol for the first two months to the isoniazid + rifampin therapy of tuberculosis serves the following purpose(s): A. Reduces the total duration of therapy to 6 months B. ... sputum conversion C. Permits reduction of rifampin dose D. Both A' and B' are correct

Last Answer : D. Both ‘A’ and ‘B’ are correc

Which of the following is a neuroglucopenic symptom of hypoglycaemia: A. Sweating B. Palpitation C. Tremor D. Abnormal behaviour

Description : Which of the following is a neuroglucopenic symptom of hypoglycaemia: A. Sweating B. Palpitation C. Tremor D. Abnormal behaviour

Last Answer : D. Type 2 diabetes patients not controlled by a biguanide drug

Hydralazine is a directly acting vasodilator, but is not used alone as an antihypertensive because: A. By itself, it is a low efficacy antihypertensive B. Effective doses cause marked postural hypotension C. Tolerance to the antihypertensive action develops early due to counterregulatory mechanisms D. It primarily reduces systolic blood pressure with little effect on diastolic blood pressure

Description : Hydralazine is a directly acting vasodilator, but is not used alone as an antihypertensive because: A. By itself, it is a low efficacy antihypertensive B. Effective doses cause marked ... mechanisms D. It primarily reduces systolic blood pressure with little effect on diastolic blood pressure

Last Answer : C. Tolerance to the antihypertensive action develops early due to counterregulatory mechanisms

Ethanol is used in methanol poisoning because it: A. Antagonises the actions of methanol B. Stimulates the metabolism of methanol and reduces its blood level C. Inhibits the metabolism of methanol and generation of toxic metabolite D. Replenishes the folate stores depleted by methano

Description : Ethanol is used in methanol poisoning because it: A. Antagonises the actions of methanol B. Stimulates the metabolism of methanol and reduces its blood level C. Inhibits the metabolism of methanol and generation of toxic metabolite D. Replenishes the folate stores depleted by methano

Last Answer : C. Inhibits the metabolism of methanol and generation of toxic metabolite

Recrudescence of malaria refers to recurrence of malarial fever due to: A. Reinfection of the patient by mosquito bite B. Reinfection of blood by exoerythrocytic hypnozoites C. Incomplete clearance of schizonts from blood D. Any of the above

Description : Recrudescence of malaria refers to recurrence of malarial fever due to: A. Reinfection of the patient by mosquito bite B. Reinfection of blood by exoerythrocytic hypnozoites C. Incomplete clearance of schizonts from blood D. Any of the above

Last Answer : C. Incomplete clearance of schizonts from blood

An adult patient of acute diarrhoea presents with abdominal pain, fever, mucus and blood in stools and is suspected to be suffering from Shigella enteritis. What antimicrobial treatment would be most appropriate: A. No antimicrobial treatment B. Metronidazole C. Norfloxacin D. Chloramphenicol

Description : An adult patient of acute diarrhoea presents with abdominal pain, fever, mucus and blood in stools and is suspected to be suffering from Shigella enteritis. What antimicrobial treatment would be most appropriate: A. No antimicrobial treatment B. Metronidazole C. Norfloxacin D. Chloramphenicol

Last Answer : C. Norfloxacin

Choose the drug which alters surface receptors on platelet membrane to inhibit aggregation, release reaction and to improve platelet survival in extracorporeal circulation: A. Dipyridamole B. Ticlopidine C. Aspirin D. Heparin

Description : Choose the drug which alters surface receptors on platelet membrane to inhibit aggregation, release reaction and to improve platelet survival in extracorporeal circulation: A. Dipyridamole B. Ticlopidine C. Aspirin D. Heparin

Last Answer : B. Ticlopidine

The following drug increases cyclic-AMP in platelets and inhibits their aggregation without altering levels of thromboxane A2 or prostacyclin: A. Aspirin B. Sulfinpyrazone C. Dipyridamole D. Abciximab

Description : The following drug increases cyclic-AMP in platelets and inhibits their aggregation without altering levels of thromboxane A2 or prostacyclin: A. Aspirin B. Sulfinpyrazone C. Dipyridamole D. Abciximab

Last Answer : C. Dipyridamole

Aspirin prolongs bleeding time by inhibiting the synthesis of: A. Clotting factors in liver B. Prostacyclin in vascular endothelium C. Cyclic AMP in platelets D. Thromboxane A2 in platelets

Description : Aspirin prolongs bleeding time by inhibiting the synthesis of: A. Clotting factors in liver B. Prostacyclin in vascular endothelium C. Cyclic AMP in platelets D. Thromboxane A2 in platelets

Last Answer : D. Thromboxane A2 in platelets

The most effective drug for prevention of stroke in atrial fibrillation patients is: A. Aspirin B. Warfarin C. Low dose subcutaneous heparin D. Digoxin

Description : The most effective drug for prevention of stroke in atrial fibrillation patients is: A. Aspirin B. Warfarin C. Low dose subcutaneous heparin D. Digoxin

Last Answer : B. Warfarin

An opioid analgesic is preferred over aspirin like analgesic in the following condition: A. Acute gout B. Burn C. Toothache D. Neuralgi

Description : An opioid analgesic is preferred over aspirin like analgesic in the following condition: A. Acute gout B. Burn C. Toothache D. Neuralgi

Last Answer : B. Burn

The drug of choice for trigeminal neuralgia is: A. Aspirin B. Imipramine C. Carbamazepine D. Valproic acid

Description : The drug of choice for trigeminal neuralgia is: A. Aspirin B. Imipramine C. Carbamazepine D. Valproic acid

Last Answer : C. Carbamazepine