Blood level of which clotting factor declines most rapidly after the initiation of warfarin therapy: A. Factor VII B. Factor IX C. Factor X D. Prothrombin

Blood level of which clotting factor declines most
rapidly after the initiation of warfarin therapy:
A. Factor VII
B. Factor IX
C. Factor X
D. Prothrombin
by

1 Answer

Answer :

A. Factor VII
by

Related questions

The standard management oral anticoagulant therapy for chronic treatment of venous thromboembolism is with the drug warfarin. Which of the following statement(s) is/are true concerning the administration of warfarin? a. An important complication of warfarin therapy is skin necrosis in patients with protein C deficiency b. Warfarin interferes with vitamin K dependent clotting factors II, VII, IX, X c. For effective anticoagulation the prothrombin time (PT) should be kept at 2 control d. It is recommended that warfarin be continued for at least one year after initial episode of deep venous thrombosis

Description : The standard management oral anticoagulant therapy for chronic treatment of venous thromboembolism is with the drug warfarin. Which of the following statement(s) is/are true concerning the administration ... warfarin be continued for at least one year after initial episode of deep venous thrombosis

Last Answer : Answer: a, b Warfarin interferes with the vitamin K dependent clotting factors II, VII, IX and X, protein C, and protein S. An important complication of warfarin is skin ... the benefit from anticoagulant therapy and thus is the basis for discontinuing warfarin administration at this time

he primary mechanism by which heparin prevents coagulation of blood is: A. Direct inhibition of prothrombin to thrombin conversion B. Facilitation of antithrombin III mediated inhibition of factor Xa and thrombin C. Activation of antithrombin III to inhibit factors IX and XI D. Inhibition of factors XIIa and XIIIa

Description : he primary mechanism by which heparin prevents coagulation of blood is: A. Direct inhibition of prothrombin to thrombin conversion B. Facilitation of antithrombin III mediated inhibition of factor Xa and ... of antithrombin III to inhibit factors IX and XI D. Inhibition of factors XIIa and XIIIa

Last Answer : B. Facilitation of antithrombin III mediated inhibition of factor Xa and thrombi

Vitamin K regulates the synthesis of blood clotting factors. (A) VII (B) IX (C) X (D) All of these

Description : Vitamin K regulates the synthesis of blood clotting factors. (A) VII (B) IX (C) X (D) All of these

Last Answer : Answer : D

Vitamin K regulates the synthesis of blood clotting factors: (A) VII (B) IX (C) X (D) All of these

Description : Vitamin K regulates the synthesis of blood clotting factors: (A) VII (B) IX (C) X (D) All of these

Last Answer : Answer : D

Tests of coagulation are used to monitor anticoagulation treatment and detect intrinsic abnormalities in coagulation. Which of the following statement(s) is/are true concerning coagulation tests? a. Prothrombin time (PT) measures both the intrinsic and extrinsic clotting pathways and fibrinogen b. Activated partial thromboplastin time (aPTT) can be used to monitor both oral anticoagulation with Warfarin and intravenous anticoagulation with heparin c. Thrombin clotting time (TCT) is a measurement of the time it takes for exogenously administered thrombin to turn plasma fibrinogen into fibrin clot d. Whole blood activated clotting time (ACT) is a measurement of the ability of whole blood to clot and is used to monitor heparin levels intraoperatively during cardiovascular and peripheral vascu

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The transfusion of fresh frozen plasma (FFP) is indicated for which of the following reasons? A. Volume replacement. B. As a nutritional supplement. C. Specific coagulation factor deficiency with an abnormal prothrombin time (PT) and/or an abnormal activated partial thromboplastin time (APTT). D. For the correction of abnormal PT secondary to warfarin therapy, vitamin K deficiency, or liver disease.

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Which of the following is not true about warfarin, a. INR of 3 is enough to start any extraction. b. Affects extrinsic system and increases prothrombin time. c. Heparin can be given subcutaneously and acts rapidly. d. It takes at least 12 hours for Vitamin K to reverse the effects of coumarin.

Description : Which of the following is not true about warfarin, a. INR of 3 is enough to start any extraction. b. Affects extrinsic system and increases prothrombin time. c. Heparin can be given subcutaneously ... rapidly. d. It takes at least 12 hours for Vitamin K to reverse the effects of coumarin.

Last Answer : d. It takes at least 12 hours for Vitamin K to reverse the effects of coumarin.

Which of the following is not true about warfarin, ** A. INR of 3 is enough to start any extraction B. Affects extrinsic system and decreases prothrombin time C. Heparin can be given subcutaneously and acts rapidly D. It takes up to 12 hours for Vitamin K to reverse the effects of warfarin

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Last Answer : B. Affects extrinsic system and decreases prothrombin time

The following statements are true of oral anticoagulants except: A. They interfere with an early step in the synthesis of clotting factors B. Irrespective of the dose administered, their anticoagulant effect has a latency of onset of 1-3 days C. Their dose is adjusted by repeated measurement of prothrombin time D. They are contraindicated during pregnancy

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Last Answer : A. They interfere with an early step in the synthesis of clotting factors

Combined therapy with dipyridamole and warfarin is recommended in subjects with the following: A. Risk factors for coronary artery disease B. Prosthetic heart valves C. Cerebral thrombosis D. Buerger's disease

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Last Answer : B. Prosthetic heart valves

Hemophilia A is characterised by deficiency of Options: 1) Factor VII 2) Factor VIII 3) Factor IX 4) Factor XI

Description : Hemophilia A is characterised by deficiency of Options: 1) Factor VII 2) Factor VIII 3) Factor IX 4) Factor XI

Last Answer : Correct Answer: 2) Factor VIII

The prothrombin time a. assess the extrinsic pathway of the blood coagulation cascade b. is prolonged in patients with fat absorption c. is increased by warfarin d. all above

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Last Answer : all above

The prothrombin time a. assess the extrinsic pathway of the blood coagulation cascade b. is prolonged in patients with fat absorption c. is increased by warfarin d. is increased by heparin

Description : The prothrombin time a. assess the extrinsic pathway of the blood coagulation cascade b. is prolonged in patients with fat absorption c. is increased by warfarin d. is increased by heparin

Last Answer : assess the extrinsic pathway of the blood coagulation cascade

Which of the following statement(s) is/are true concerning hemophilia A? a. Hemophilia A is inherited as a sex-linked recessive deficiency of factor VIII b. A positive family history for bleeding disorders present in all patients c. Laboratory tests reveal a prolongation of aPTT, prothrombin time (PT), thrombin clotting time and platelet aggregation d. Spontaneous bleeding is unusual with factor VIII levels greater than 10% of normal

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Following is not the clotting factor ___________ a. Fibrinogen b. Prothrombin c. Hageman factor d. Ferritin

Description : Following is not the clotting factor ___________ a. Fibrinogen b. Prothrombin c. Hageman factor d. Ferritin

Last Answer : d. Ferritin

Transdermal estradiol differs from oral estrogen therapy in that it: A. Causes less induction of hepatic synthesis of clotting factors B. Does not inhibit FSH secretion C. Does not affect vaginal cytology D. All of the above are correct

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I have some matchsticks set up like this: I + XI = X. If you do not know Roman numerals, here is a quick starter: I=1 II=2 III=3 IV=4 V=5 VI=6 VII=7 VIII=8 IX=9 X=10 XI=11 XII=12 XIII=13 XIV=14 XV=15...... Of course, I + XI = X is wrong. You are told to move the minimum number of matchsticks to make the question correct. So, how many do you have to move? -Riddles

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Last Answer : Most people would get to one move at the least, but the real answer is zero moves. If you rotate the whole question around 180 degrees, it will display this: X = IX + I

Cold conc. `HNO_(3)` will completely dissolve: (i) Pb (ii) `Pb_(3)O_(4)` (iii) Fe (iv) Sn (v) Mg (vi) MgO (vii) Hg (viii) Au (ix) Ag (x) Pt

Description : Cold conc. `HNO_(3)` will completely dissolve: (i) Pb (ii) `Pb_(3)O_(4)` (iii) Fe (iv) Sn (v) Mg (vi) MgO (vii) Hg (viii) Au (ix) Ag (x) Pt

Last Answer : Cold conc. `HNO_(3)` will completely dissolve: (i) Pb (ii) `Pb_(3)O_(4)` (iii) Fe (iv) Sn (v) Mg (vi) MgO (vii) Hg (viii) Au (ix) Ag (x) Pt

Cold conc. `HNO_(3)` will completely dissolve: (i) Pb (ii) `Pb_(3)O_(4)` (iii) Fe (iv) Sn (v) Mg (vi) MgO (vii) Hg (viii) Au (ix) Ag (x) Pt

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Which of the statements listed below about bleeding disorders is/are correct? A. Acquired bleeding disorders are more common than congenital defects. B. Deficiencies of vitamin K decrease production of factors II, VII, IX, and X, protein C, and protein S. C. Hypothermia below 32؛C rarely causes a bleeding disorder. D. Von Willebrand's disease is a very uncommon congenital bleeding disorder.

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Last Answer : Answer: AB DISCUSSION: Acquired bleeding disorders are significantly more common than congenital bleeding defects. Vitamin K deficiency may be related to malnutrition or competitive inhibition ... a relatively common disorder of bleeding and is generally undetectable by routine screening methods

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Last Answer : Answers: (i) Artery and vein: Arteries: Muscular blood vessels that carry blood away from the heart. All arteries, with the exception of the pulmonary and umbilical arteries, carry oxygenated blood ... to determine cause of death Biopsy: Removal and study of a tissue sample for diagnostic purposes

Name the quantities which are measured by the following units. (i) Newton (ii) Joule (iii) Watt (iv) Volt (v) Light year (vi) Angstrom (vii) Acre-foot (viii) Becquerel (ix) Hertz (x) Cusec

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Which quantity do the following units measure: (i) Volt (ii) Coulomb (iii) Walt (iv) Ohm (v) Mho (vi) Ampere (vii) Dyne (viii) Celsius (ix) Joule (x) Calorie

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Last Answer : Answers: (i) Voltage (ii) Charge of Electricity (iii) Power (iv) Resistance (v) Conductivity (vi) Current (vii) Force (viii) Temperature (ix) Energy (x) Heat

Which of the following cranial nerves can regulate heart beat? (a) X (b) IX (c) VIII (d) VII

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Last Answer : a) X

Vagus nerve is (a) X (b) IX (c) VII (d) V.

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A company has to choose between two projects whose cash flows are as indicated below; Project 1: i. Investment – Rs. 15 Lakhs ii. Annual cost savings – Rs. 4 lakhs. iii. Bi-annual maintenance cost – Rs. 50,000/- iv. Reconditioning and overhaul during 5th year: 6 lakhs v. Life of the project – 8 years vi. Salvage value – Rs. 5 lakhs Project 2: vii. Investment – Rs. 14 Lakhs viii. Annual cost savings – Rs. 3.5 lakhs. ix. Annual Maintenance cost – Rs. 20,000/- x. Reconditioning and overhaul during 4th year: 5 lakhs xi. Life of the project – 8 years xii. Salvage Value- 2 lakhs Which project should the company choose? The annual discount rate is 12

Description :  A company has to choose between two projects whose cash flows are as indicated  below; Project 1:  i. Investment - Rs. 15 Lakhs ii. Annual cost savings - Rs. 4 lakhs. iii. Bi-annual ... years xii. Salvage Value- 2 lakhs Which project should the company choose? The annual discount rate is 12

Last Answer : Year Project 1 Project 2 Outgo Saving NPV Outgo Saving NPV 0 15.0 0 =-15.0 14.0 0 = -14 1 0 4.0 = (4 / (1+.12)1 = 3.571 0.2 3.5 = (3.3 / (1+.12)1 = 2.95 2 0.5 4.0 = (3.5 / (1+.12)2 = 2.79 0.2 3.5 ... (1+.12)8 = 3.43 0.2 5.5  (3.5+2) = (5.3 / (1+.12)8 = 2.14 NPV = + 2.301 @12% = + 0.15

One of the practical applications of genetic engineering is the bacterial production of ____.a. human insulin. b. human growth hormone c. blood clotting factors VIII and IX d. antiviral proteins e. all of the above

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What is the importance of prothrombin in blood clotting? -Biology

Description : What is the importance of prothrombin in blood clotting? -Biology

Last Answer : answer:

Prothrombin which helps in clotting of blood is released by?

Description : Prothrombin which helps in clotting of blood is released by?

Last Answer : blood platelets

A patient on dicoumarol treatment needs extraction. Which of the following is MOST valuable in evaluating surgical risks: A. Clotting time B. Bleeding time C. Prothrombin time D. Sedimentation rate E. Complete blood cell count

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The following is true of anti-H.pylori therapy except: A. It is indicated in all patients of peptic ulcer B. Resistance to any single antimicrobial drug develops rapidly C. Concurrent suppression of gastric acid enhances efficacy of the regimen D. Colloidal bismuth directly inhibits H.pylori but has poor patient acceptability

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Last Answer : A. It is indicated in all patients of peptic ulcer

Cold dil. `H_(2)SO_(4)` will completely dissolve : (i) Pb (ii) `Fe_(3)O_(4)` (iii) Fe (iv) Cu (v) Mg (vi) MgO (vii) `CoCO_(3)` (viii) `CuCO_(2)` (ix)

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(i) `NH_(3)` (ii) `N_(2)H_(4)` (iii) `HN_(3)` (iv) `PH_(3)` (v) `H_(2)S` (vi) `AsH_(3)` (vii) `SbH_(3)` (viii) `H_(2)Se` (ix) `H_(2)Te` Number of mole

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(i) `NH_(3)` (ii) `N_(2)H_(4)` (iii) `HN_(3)` (iv) `PH_(3)` (v) `H_(2)S` (vi) `AsH_(3)` (vii) `SbH_(3)` (viii) `H_(2)Se` (ix) `H_(2)Te` Number of mole

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In which Part of the Constitution of India we find the provisions relating to citizenship? (1) Part I (2) Part II (3) Part VII (4) Part IX

Description : In which Part of the Constitution of India we find the provisions relating to citizenship? (1) Part I (2) Part II (3) Part VII (4) Part IX

Last Answer : (2) Part II Explanation: Part II of the Constitution of India (Articles 5-11) deals with the Citizenship of India. Citizenship constitutes the indispensable foundational principle of democratic polity.

If mammalian ovum fails to get fertilised, which one of the following is unlikely? (a) Corpus luteum will disintegrate. (b) Progesterone secretion rapidly declines. (c) Estrogen secretion further increases. (d) Primary follicle starts developing.

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Last Answer : (c) Estrogen secretion further increases.

Iron is not used alone as a catalyst in ammonia synthesis, because (A) Its activity declines rapidly, if heated to above 520°C (B) It decomposes ammonia (C) It gets oxidised above 500°C (D) None of these

Description : Iron is not used alone as a catalyst in ammonia synthesis, because (A) Its activity declines rapidly, if heated to above 520°C (B) It decomposes ammonia (C) It gets oxidised above 500°C (D) None of these

Last Answer : (A) Its activity declines rapidly, if heated to above 520°C

Low molecular weight heparins differ from unfractionated heparin in that: A. They selectively inhibit factor Xa B. They do not significantly prolong clotting time C. They are metabolized slowly and have longer duration of action D. All of the above are correct

Description : Low molecular weight heparins differ from unfractionated heparin in that: A. They selectively inhibit factor Xa B. They do not significantly prolong clotting time C. They are metabolized slowly and have longer duration of action D. All of the above are correct

Last Answer : D. All of the above are correct

The following action(s) of heparin is/are essential for inhibition of factor Xa: A. Facilitation of antithrombin III mediated inhibition of factor XIIa B. Provision of scaffold for the clotting factor to interact with antithrombin III C. Induction of a configurational change in antithrombin III to expose its interacting sites D. Both ‘A’ and ‘B

Description : The following action(s) of heparin is/are essential for inhibition of factor Xa: A. Facilitation of antithrombin III mediated inhibition of factor XIIa B. Provision of scaffold for the clotting factor ... configurational change in antithrombin III to expose its interacting sites D. Both A' and B

Last Answer : C. Induction of a configurational change in antithrombin III to expose its interacting sites

Patient with haemophilia presents which of the following findings:** A. Increased prothrombin time B. Increased bleeding time C. Increased clotting time

Description : Patient with haemophilia presents which of the following findings:** A. Increased prothrombin time B. Increased bleeding time C. Increased clotting time

Last Answer : A. Increased prothrombin time

Bleeding complications are frequently associated with fibrinolytic therapy. Which of the following statement(s) concerning complications of fibrinolytic therapy is/are true? a. Careful monitoring of prothrombin time and aPTT time are necessary to avoid bleeding complications b. A level of serum fibrinogen less than 100 mg/dl is associated with an increased risk of bleeding c. Recent (less than 10 days) major surgery is a contraindication to systemic but not regional fibrinolytic therapy d. A patient with a cerebrovascular event occurring less than two months ago can be treated with fibrinolytic therapy if head CT scan is normal

Description : Bleeding complications are frequently associated with fibrinolytic therapy. Which of the following statement(s) concerning complications of fibrinolytic therapy is/are true? a. Careful monitoring of prothrombin time ... months ago can be treated with fibrinolytic therapy if head CT scan is normal

Last Answer : Answer: b Fibrinolytic therapy induces a hemostatic defect through a combination of factors. Hypofibrinogenemia and fibrin degradation products inhibit fibrin polymerization and, in combination ... is considered a major relative contraindication to either regional or systemic thrombolytic therapy

A patient of megaloblastic anaemia was treated with oral folic acid 5 mg daily. After 2 weeks he reported back with cognitive deficit, sensory disturbance, depressed knee jerk, while blood picture and haemoglobin level were improved. What could be the most likely explanation: A. Folic acid was not adequately absorbed resulting in partial response B. Folate therapy has precipitated vitamin B12 deficiency in the neural tissue C. Folate therapy has unmasked pyridoxine deficiency D. Patient has folate reductase abnormality in the nervous system

Description : A patient of megaloblastic anaemia was treated with oral folic acid 5 mg daily. After 2 weeks he reported back with cognitive deficit, sensory disturbance, depressed knee jerk, while ... therapy has unmasked pyridoxine deficiency D. Patient has folate reductase abnormality in the nervous system

Last Answer : D. Patient has folate reductase abnormality in the nervous system

The distinctive feature(s) of sparfloxacin compared to ciprofloxacin is/are: A. Enhanced activity against gram positive bacteria B. Lack of pharmacokinetic interaction with theophylline and warfarin C. Higher incidence of phototoxic reaction D. All of the above

Description : The distinctive feature(s) of sparfloxacin compared to ciprofloxacin is/are: A. Enhanced activity against gram positive bacteria B. Lack of pharmacokinetic interaction with theophylline and warfarin C. Higher incidence of phototoxic reaction D. All of the above

Last Answer : D. All of the above

The most effective drug for prevention of stroke in atrial fibrillation patients is: A. Aspirin B. Warfarin C. Low dose subcutaneous heparin D. Digoxin

Description : The most effective drug for prevention of stroke in atrial fibrillation patients is: A. Aspirin B. Warfarin C. Low dose subcutaneous heparin D. Digoxin

Last Answer : B. Warfarin

You are treating a patient of deep vein thrombosis with warfarin. What value of International normalized ratio (INR) will you attempt by adjusting dose of the anticoagulant for an adequate therapeutic effect: A. 1.2 – 1.5 B. 1.3 – 1.7 C. 1.5 – 2.0 D. 2.0 – 3.0

Description : You are treating a patient of deep vein thrombosis with warfarin. What value of International normalized ratio (INR) will you attempt by adjusting dose of the anticoagulant for an adequate therapeutic effect: A. 1.2 – 1.5 B. 1.3 – 1.7 C. 1.5 – 2.0 D. 2.0 – 3.0

Last Answer : D. 2.0 – 3.0

The patient whom you are about to treat states that he has Von Willebrand’s disease. Which one of the following preoperative haematological analyses may reflect this disease: A. Bleeding time and factor VIII level ptt also prolonged decreased platelet count. B. Bleeding time and factor IX level C. Bleeding time and factor X level D. Platelet count E. Thromboplastin generation time

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Last Answer : A. Bleeding time and factor VIII level ptt also prolonged decreased platelet count

A patient of iron deficiency anaemia has been put on iron therapy. What should be the rate of rise in haemoglobin level of blood so that response is considered adequate: A. 0.05 – 0.1 g% per week B. 0.1 – 0.2 g% per week C. 0.5 – 1.0 g% per week D. More than 1.0 g% per week

Description : A patient of iron deficiency anaemia has been put on iron therapy. What should be the rate of rise in haemoglobin level of blood so that response is considered adequate: A. 0.05 – 0.1 g% per week B. 0.1 – 0.2 g% per week C. 0.5 – 1.0 g% per week D. More than 1.0 g% per week

Last Answer : C. 0.5 – 1.0 g% per week

A 40-year-old politician suffered from attacks of chest pain diagnosed as angina pectoris. He had a tense personality, resting heart rate was 96/min, blood pressure 170/104 mm Hg, but blood sugar level and lipid profile were normal. Select the most suitable antihypertensive for initial therapy in his case: A. Nifedipine B. Hydrochlorothiazide C. Atenolol D. Methyldopa

Description : A 40-year-old politician suffered from attacks of chest pain diagnosed as angina pectoris. He had a tense personality, resting heart rate was 96/min, blood pressure 170/104 mm Hg, but ... antihypertensive for initial therapy in his case: A. Nifedipine B. Hydrochlorothiazide C. Atenolol D. Methyldopa

Last Answer : C. Atenolol

Low doses of heparin prolong: A. Bleeding time B. Activated partial thromboplastin time C. Prothrombin time D. Both ‘B’ and ‘C’

Description : Low doses of heparin prolong: A. Bleeding time B. Activated partial thromboplastin time C. Prothrombin time D. Both ‘B’ and ‘C’

Last Answer : B. Activated partial thromboplastin time