Indicate the attribute that is common to both polymyxin B and bacitracin: A. Both are active against gram negative bacteria B. Both are too toxic for systemic use C. Both act by inhibiting bacterial cell wall synthesis D. Both a

Indicate the attribute that is common to both polymyxin B and bacitracin:
A. Both are active against gram negative bacteria
B. Both are too toxic for systemic use
C. Both act by inhibiting bacterial cell wall synthesis
D. Both a
by

1 Answer

Answer :

B. Both are too toxic for systemic use
by

Related questions

The following is true of vancomycin except: A. It is a bactericidal antibiotic active primarily against gram positive bacteria B. It acts by inhibiting bacterial protein synthesis C. It is an alternative to penicillin for enterococcal endocarditis D. It can cause deafness as a dose related toxicity

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Last Answer : B. It acts by inhibiting bacterial protein synthesis

The most important mechanism by which tetracycline antibiotics exert antimicrobial action is: A. They chelate Ca2+ ions and alter permeability of bacterial cell membrane B. They bind to 30S ribosomes and inhibit bacterial protein synthesis C. They bind to 50S ribosomes and interfere with translocation of the growing peptide chain in the bacteria D. They interfere with DNA mediated RNA synthesis in bacteria

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Last Answer : B. They bind to 30S ribosomes and inhibit bacterial protein synthesis

What is true of Quinupristin-Dalfopristin: A. It is a synergistic combination of two similar antibiotics B. It acts by inhibiting bacterial protein synthesis C. It is active against most resistant coccal infections D. All of the above are correct

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Last Answer : D. All of the above are correct

Penicillins interfere with bacterial cell wall synthesis by: A. Inhibiting synthesis of N-acetyl muramic acid pentapeptide B. Inhibiting conjugation between N-acetyl muramic acid and N-acetyl glucosamine C. Inhibiting transpeptidases and carboxypeptidases which cross link the peptidoglycan residues D. Counterfeiting for D-alanine in the bacterial cell wall

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Last Answer : C. Inhibiting transpeptidases and carboxypeptidases which cross link the peptidoglycan residues

Aminoglycoside antibiotics have the following property common to all members: A. They are primarily active against aerobic gram negative bacilli B. They are more active in acidic medium C. They readily enter cells and are distributed in total body water D. They are nearly completely metabolized in liver

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Last Answer : A. They are primarily active against aerobic gram negative bacilli

Semisynthetic penicillins developed so far have overcome the following drawbacks of benzylpenicillin except: A. Lack of efficacy against gram negative bacilli B. Susceptibility to bacterial penicillinase C. Inactivation by gastric acid D. Potential to cause hypersensitivity reactions

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The most important mechanism by which gram negative bacilli acquire chloramphenicol resistance is: A. Decreased permeability into the bacterial cell B. Acquisition of a plasmid encoded for chloramphenicol acetyl transferase C. Lowered affinity of the bacterial ribosome for chloramphenicol D. Switching over from ribosomal to mitochondrial protein synthesi

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Increasing evidence has implicated gram-negative bacterial lipopolysaccharide (LPS endotoxin) as the portion of the gram-negative bacterial cell membrane responsible for many, if not all the toxic effects that occur during gram-negative bacterial sepsis. The following statement(s) is/are true concerning LPS and the host response. a. The LPS molecule can in itself cause physiologic responses similar to that seen during gram-negative bacterial sepsis b. LPS triggers host macrophages to release a variety of cytokines including TNF-a, IL-1a, and IL-1b, IL-6, and IFN-a c. Excessive cytokine production is not associated with detrimental consequences d. TNFa and IL-1b appear to be the primary mediators within the host, exerting deleterious effects on the host when excessive amounts reach the syst

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Features of clindamycin include the following: A. It is primarily active against aerobic gram negative bacilli B. It can be used topically to treat infected acne vulgaris C. It is not absorbed orally D. It is used to treat pseudomembranous enterocolitis

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Tetracyclines are active against the following gram negative bacteria: A. Salmonella typhi B. Pseudomonas aeruginosa C. Yersinia pestis D. All of the above

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The third generation cephalosporins differ from the first generation cephalosporins in that they are: A. More active against gram positive cocci B. More active against gram negative enterobacteriaceae C. Nonimmunogenic D. Not excreted by tubular secretion

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Nalidixic acid is primarily active against: A. Cocci B. Bacilli C. Gram positive bacteria D. Gram negative bacteria

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Last Answer : D. Gram negative bacteria

Gram negative organisms are largely insensitive to benzyl penicillin because: A. They produce large quantities of penicillinase B. They do not utilise D-alanine whose incorporation in the cell wall is inhibited by benzylpenicillin C. Benzyl penicillin is not able to penetrate deeper into the lipoprotein-peptidoglycan multilayer cell wall of gram negative bacteria D. Both ‘A’ and ‘B’ are correct

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Chloramphenicol inhibits bacterial protein synthesis by: A. Binding to 30S ribosome and inhibiting attachment of aminoacyl tRNA B. Binding to 50S ribosome and preventing peptide bond formation C. Binding to 50S ribosome and blocking translocation of peptide chain D. Binding to both 30S and 50S ribosome and inducing misreading of mRNA code

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The following statement is true about ketoconazole except: A. It is less toxic than amphotericin B B. It produces a slower response than amphotericin B in systemic mycosis C. Given orally it is the first line treatment for vaginal candidiasis D. It is not effective in fungal meningitis

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Penicillins interfere with bacterial cell wall synthesis by (a) Inhibiting synthesis of N-acetyl muramic acid pentapeptide (b) Inhibiting conjugation between N-acetyl muramic acid and N-acetyl glucosamine (c) Inhibiting transpeptidases and carboxy peptidases which cross link the peptidoglycan residues (d) Counterfeiting for D-alanine in the bacterial cell wall

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Last Answer : Ans: C

The sulfonamides interfere with bacterial metabolism by a. blocking cell wall synthesis. b. disrupting folic acid metabolism. c. reacting with bacterial cell membranes. d. inhibiting DNA replication.

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The following is true of linezolid except: A. It inhibits bacterial protein synthesis at an early step B. It is active against vancomycin resistant enterococci C. It is the drug of choice for enterococcal endocarditis D. It can be administered orally as well as by i.v. infusion

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The following statement(s) is/are true concerning gram-negative bacterial sepsis. a. Mortality due to this condition has almost been eliminated due to therapeutic intervention with antibiotics, aggressive hemodynamic monitoring and fluid resuscitation b. Recent series have noted a decrease in the incidence of this condition c. Predisposing factors include old age, malnutrition, and immunosuppression d. Pseudomonas bacteremia is the most common cause of gram-negative sepsis e. Polymicrobial sepsis is generally considered a more serious problem than sepsis due to a single organism

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Which of the following is not an attribute of amlodipine: A. Generation of an active metabolite B. Large volume of distribution C. High and consistent oral bioavailability D. Long elimination half life

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An adult patient with a history of bacterial endocarditis requires prophylactic administration of antibiotics prior to removal of teeth. Indicate the pre-operative regimen:** A. Amoxicillin 2 gram one hour before operation orally B. Penicillin 250 mg orally six hours before operation C. Tetracycline 250-500 mg orally 2 hours before treatment

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Last Answer : A. Amoxicillin 2 gram one hour before operation orally

Which of the following statement(s) is/are true concerning septic shock? a. The clinical picture of gram negative septic shock is specifically different than shock associated with other infectious agents b. The circulatory derangements of septic shock precede the development of metabolic abnormalities c. Splanchnic vascular resistance falls in similar fashion to overall systemic vascular resistance d. Despite normal mechanisms of intrinsic expansion of the circulating blood volume, exogenous volume resuscitation is necessary

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What is the relationship between the observed gram reaction and bacterial cell wall structure?

Description : What is the relationship between the observed gram reaction and bacterial cell wall structure?

Last Answer : Feel Free to Answer

The most important mechanism by which gram negative bacilli acquire chloramphenicol resistance is (a) Decreased permeability into the bacterial cell (b) Acquisition of a plasmid encoded for chloramphenicol acetyl transferase (c) Lowered affinity of the bacterial ribosome for chloramphenicol (d) Switching over from ribosomal to mitochondrial protein synthesis

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Last Answer : Ans: B

If a necrotizing soft tissue infection is considered, therapy mandates: a. Empiric administration of antibiotics active against gram-positive, gram-negative, and anaerobic bacteria b. Due to usually resistant species, penicillin is not indicated c. Immediate operative intervention and aggressive resection of all involved tissues is mandatory d. The use of hyperbaric oxygen has been demonstrated to be clearly advantageous

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Choose the correct statement(s) about auranofin: A. It is an orally active gold compound B. It is equally effective but less toxic than injected gold-sodium-thiomalate C. Its major adverse effect is dermatitis D. All of the above are correct

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Cefotaxime has the following properties except (a) It is highly active against aerobic gram negative bacteria (b) It is the most active cephalosporin against Pseudomonas aeruginosa (c) It produces an active metabolite (d) It has achieved high cure rates in serious hospital acquired infections

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Last Answer : Ans: B

Furosemide acts by inhibiting the following in the renal tubular cell: A. Na+-K+-2Cl– cotransporter B. Na+-Cl– symporter C. Na+-H+ antiporter D. Na+ K+ ATPase

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Last Answer : A. Na+-K+-2Cl– cotransporter

The following is true for gentamicin: A. It is more active in acidic medium B. It has a wide margin of safety C. It is excreted unchanged, mainly by glomerular filtration D. It primarily inhibits gram positive bacteria

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Last Answer : C. It is excreted unchanged, mainly by glomerular filtration

Gram negative organisms are largely insensitive to benzyl penicillin because (a) They produce large quantities of penicillinase (b) They do not utilize D-alanine whose incorporation in the cell wall is inhibited by benzyl penicillin (c) Benzyl penicillin is not able to penetrate deeper into the lipoprotein-peptidoglycan multiplayer cell wall of gram-negative bacteria (d) Both (a) and (b)

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Last Answer : Ans: C

The cell wall of A.gram-positive bacteria are thicker than gram-negative bacteria B.gram-negative bacteria are thicker than gram-positive bacteria C.both have same thickness but composition is different D.none of these

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Last Answer : A.gram-positive bacteria are thicker than gram-negative bacteria

The cell wall of A- gram-positive bacteria are thicker than gram-negative bacteria B- gram-negative bacteria are thicker than gram-positive bacteria C- both have same thickness but composition is different D- none of these

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