Description : While prescribing a first generation H1 antihistaminic the patient should be advised to avoid: A. Driving motor vehicles B. Consuming processed cheese C. Strenuous physical exertion D. All of the above
Last Answer : A. Driving motor vehicles
Description : The following precaution should be advised to the patient while prescribing metronidazole: A. To avoid driving B. To get leucocyte count checked every second day C. To avoid fatty/fried food D. To avoid alcoholic beverages
Last Answer : D. To avoid alcoholic beverages
Description : H1 antihistaminics are beneficial in (a) All types of allergic disorders (b) Certain type I allergic reactions only (c) Anaphylactic shock(d) Bronchial asthma
Last Answer : Ans: B
Description : Fall in blood pressure caused by larger doses of histamine is blocked by (a) H1 antihistaminics alone (b) H2 ANTAgonists alone (c) Combination of H1 and H2 antagonists (d) None of the above
Last Answer : Ans: C
Description : The second generation H1 antihistaminics have the following advantages except: A. Lack of anticholinergic side effects B. Lack of alcohol potentiating potential C. Recipient can drive motor vehicles D. Good antipruritic action
Last Answer : D. Good antipruritic action
Description : The conventional H1 antihistaminics possess the following additional properties except: A. Local anaesthetic B. Vasopressor C. Antiarrhythmic D. Catecholamine potentiating
Last Answer : B. Vasopressor
Description : Smooth muscle relaxation is due to stimulation of which type of histamine receptors (a) H1 (b) H2 (c) H3 (d) All of the above
Description : The most important receptor involved in cytotoxic drug induced vomiting is (a) Histamine H1 receptor (b) Serotonin 5-HT3 receptor (c) Dopamine D2 receptor (d) Opioid µ receptor
Description : Select the H1 antihistaminic which is used topically in the nose for allergic rhinitis (a) Deep intra-abdominal operation (b) Trachial intubation (c) Tetanus (d) Diagonosis of myasthenia gravis
Last Answer : Ans: D
Description : The capacity of an antihistaminic to produce sedation depends on the following except (a) Relative affinity for central versus peripheral H1 receptors (b) Ability to penetrate blood-brain barrier (c) Individual susceptibility (d) Ratio of H1 : H2 blockade produced by the drug
Description : Which of the following is a selective H1 receptor agoinist ? (a) 4-methyl histamine (b) Impromidine (c) 2-Thiazolyl ethylamine (d) Mepyramine
Description : The primary goals of asthma therapy include all of the following except (a) maintain normal activity levels (b) maintain control of symptoms (c) avoid adverse effects of asthma medications (d) prevent acute exacerbations and chronic symptoms (e) prevent destruction of lung tissue
Last Answer : Ans: E
Description : Which one of the following drugs is most suitable for management of essential tremor in a patient who has pulmonary disease? (a) Diazepam (b) Levodopa (c) Metoprolol (d) Propranolol (e) Terbutaline
Description : In an asthma patient treated with systemic corticosteroids, bronchodilator drugs (a) Are not needed (b) Are contraindicated (c) May be used on ‘as and when required’ basis (d) Are ineffective
Description : In a patient of bronchial asthma, inhaled salbutamol produces the following effect(s). (a) Inhibits antigen-antibody reaction in the lungs (b) Causes bronchodilatation (c) Reduces bronchial hyperreactivity (d) Both (b) and (c)
Description : Which of the following tests is used at home to assess therapy and determine if a patient with asthma should seek emergency care? (a) Forced expiratory volume in one second (FEV1) (b) Forced vital capacity ... ) Total lung capacity (TLC) (d) Peak expiratory flow rate (PEFR) (e) Residual volume (RV)
Description : Erythromycin should not be given to patient being treated with terfenadine because (a) Erythromycin induces the metabolism of terfenadine (b) Dangerous ventricular arrhythmias can occur ... inhibits metabolism of erythromycin (d) Terfenadine antagonizes the antimicrobal action of erythromycin
Description : Which of the following agents and dosage regimens is the best choice of treatment for an asthma patient with rheumatoid arthritis who is considered sensitive to aspirin (experiences bronchospasm with use)? ... once a week (d) Azathioprine, 75 mg daily (e) Cyclophosphamide, 100 mg daily
Description : A patient undergoing cancer chemotherapy is vomiting frequently. A drug that might help in this situation is (a) Bromocriptine (b) Cimetidine (c) Ketanserin (d) Loratadine (e) Ondansetron
Description : If therapy with multiple drugs causes induction of drug metabolism in your asthma patient, it will (a) Result in increased smooth endoplasmic reticulum (b) Result in increased rough endoplasmic reticulum ... soluble cytoplasmic fraction (d) Require 3-4 months to reach completion (e) Be irreversible
Last Answer : Ans: A
Description : Which of the following terms best describes the antagonism of leukotriene's bronchoconstrictor effect (mediated at leukotriene receptors) by terbutaline (acting a adrenoceptors) in a patient with ... ) Partial agonist (c) Physiologic antagonist (d) Chemical antagonist (e) Noncompetitive antagonist
Description : Fall in blood pressure caused by larger doses of histamine is blocked by: A. H1 antihistaminics alone B. H2 antagonists alone C. Combination of H1 and H2 antagonists D. None of the above
Last Answer : C. Combination of H1 and H2 antagonists
Description : Benefit afforded by certain H1 antihistaminics in the following condition is not based on antagonism of histamine: A. Dermographism B. Insect bite C. Common cold D. Seasonal hay fever
Last Answer : C. Common cold
Description : H1 antihistaminics are beneficial in: A. All types of allergic disorders B. Certain type I allergic reactions only C. Certain type IV allergic reactions only D. Bronchial asthma
Last Answer : B. Certain type I allergic reactions only
Description : Acute exacerbations of asthma can be triggered by all of the following except (a) Bacterial or viral pneumonia (b) Hypersensitivity reaction to penicillin (c) Discontinuation of asthma medication (d) Hot, dry weather (e) Stressful emotional events
Description : The symptoms of allergen-mediated asthma result from which of the following? (a) Increased release of mediators from mast cells (b) Increased adrenergic responsiveness of the airways (c) ... bronchial tissue (d) Decreased calcium influx into the mast cell (e) Decreased prostaglandin production
Description : Bacteria that make either a fementative or respiratory set of enzymes are known as (a) Obligate anacerobes (b) Obligate aerobes (c) Microacerophiles (d) Facultative organisms
Description : Relative to fexofenadine, diphenhydramine is more likely to (a) Be used for treatment of asthma (b) Be used for treatment of gastroesophageal reflux disease (c) Cause cardiac arrhythmias in ... ) Have efficacy in the prevention of motion sickness (e) Increase the serum concentration of warfarin
Description : A drug useful in the treatment of asthma but lacking bronchodilator action, is (a) Cromolyn (b) Ephedrine (c) Isoproterenol (d) Metaproterenol (e) Metoprolol
Description : Which of the following is a very longacting ß2 – selective agonist that is used for asthma prophylaxis? (a) Aminophyline (b) Cromolyn (c) Epinephrine (d) Ipratropium (e) Salmeterol
Description : Which of the following has overdose toxicity that includes insomnia, arrhythmias, and convulsions? (a) Aminophyline (b) Cromolyn (c) Epinephrine (d) Ipratropium (e) Metaproterenol
Description : Acute exacerbations of asthma can be triggered by all of the following except (a) Bacterial of viral pneumonia (b) Hypertsensitivity reaction to penicillin (c) Discontinuation of asthma medication (d) Hot, dry weather (e) Stressful emotional events
Description : Which of the following is a direct bronchodilator that is most often used in asthma by the oral route? (a) Aminophyline (b) Cromolyn (c) Epinephrine (d) Ipratropium (e) Metaproterenol
Description : Pyridostigmine differs from neostigmine in that (a) More potent orally (b) Longer acting (c) Less muscarinic side effects (d) All of the above
Description : What is symport ? (a) Counter transport (b) Contransport (c) Carrier mediated diffusion (d) Solvent drug
Description : Which xanthine derivative has no function in asthma ? (a) Theophylline (b) Pentoxyphyllin (c) Enprofylin (d) None of the above
Description : All the following are employed in inhalation therapy of asthma except (a) Beclomethasone (b) Budesonide (c) Dexamethasone (d) Triamcinolone
Description : Chronic Bronchitis is characterized by I. the distruction of central and peripheral portions of the acinus II. an increased number of mucous glands and goblet cells III. edema and inflammation of the bronchioles (a) only ... II are correct (d) II and III are correct (e) I, II and III are correct
Description : Histamine (a) May be released from mast cells by a number of therapeutic agents (b) Causes sedation (c) Decreases the force of contraction of ventricular muscle (d) Can cause strong contractions of the gravid human uterus
Description : To be a useful inhaled glucocorticoid the drug should have (a) High oral bioavailability (b) Low oral bioavailability (c) Additional bronchodilator activity (d) Prodrug character
Description : Budesonide is a (a) Nonsteroidal anti-inflammatory drug (b) High ceiling diuretic (c) Inhaled corticosteroid for asthma (d) Contraceptive
Description : In patients of bronchial asthma inhaled corticosteroids achieve the following except (a) Reduce the need for bronchodilator medication (b) Control an attack of refractory asthma (c) Reduce bronchial hyperreactivity (d) Reverse diminished responsiveness to sympathomimetic bronchodilators
Description : Intransasal spray of budesonide is indicated in (a) Common cold (b) Acute vasomotor rhinitis (c) Perennial vasomotor rhinitis (d) Epistaxis
Description : The most consistent, pronounced and sustained relief of symptoms in chronic bronchial asthma is afforded by (a) ß2 sympathomimetics (b) Anticholinergics (c) Sodium cromoglycate (d) Corticosteroids
Description : Which of the following drugs is neither bronchodilator nor anti-inflammatory, but has antihistaminic and mast cell stabilizing activity ? (a) Sodium cromoglycate (b) Ketotifen (c) Beclomethasone dipropionate (d) Mepyramine maleate
Description : A 10 year old child suffers from exercise induced asthma: Which is the most suitable first line drug for regular prophylactic therapy ? (a) Oral salbutamol (b) Oral theophylline (c) Inhaled sodium cromoglycate (d) Inhaled beclomethasone dipropionate