Description : Finasteride acts by: A. Blocking testosterone receptors in the prostate gland B. Reducing testosterone secretion from testes C. Reducing LH secretion from pituitary D. Lowering circulating as well as prostatic dihydrotestosterone concentration
Last Answer : D. Lowering circulating as well as prostatic dihydrotestosterone concentration
Description : Which of the following is a steroid 5α-reductase inhibitor that has been found useful in benign prostatic hypertrophy and male pattern baldness: A. Flutamide B. Finasteride C. Prazosin D. Minoxidil
Last Answer : B. Finasteride
Description : Which of the following is a non-steroidal antiandrogen that is palliative in advanced carcinoma prostate when combined with a GnRH agonist: A. Cyproterone acetate B. Danazol C. Finasteride D. Flutamid
Last Answer : D. Flutamide
Description : The following is applicable to itraconazole except: A. It has largely replaced ketoconazole for treatment of systemic mycosis B. It does not inhibit human steroid hormone synthesis C. It is ... the treatment of fungal meningitis D. It can interact with terfenadine to produce ventricular arrhythmias
Last Answer : C. It is preferred for the treatment of fungal meningitis
Description : The following statement is true about ketoconazole except: A. It is less toxic than amphotericin B B. It produces a slower response than amphotericin B in systemic mycosis C. Given orally it is the first line treatment for vaginal candidiasis D. It is not effective in fungal meningitis
Last Answer : C. Given orally it is the first line treatment for vaginal candidiasis
Description : Which of the following is true of acarbose: A. It reduces absorption of glucose from intestines B. It produces hypoglycaemia in normal as well as diabetic subjects C. It limits postprandial hyperglycaemia in diabetics D. It raises circulating insulin levels
Last Answer : C. It limits postprandial hyperglycaemia in diabetics
Description : Which of the following can act as a single dose postcoital contraceptive: A. Clomiphene citrate B. Mifepristone C. Danazol D. Medroxyprogesterone acetate
Last Answer : B. Mifepristone
Description : The following is/are beneficial in endometriosis: A. Norethindrone B. Nafarelin C. Danazol D. All of the above
Last Answer : D. All of the above
Description : Choose the selective estrogen receptor modulator that is useful in dysfunctional uterine bleeding by acting as estrogen antagonist in endometrium, but does not alter vaginal epithelium or cervical mucus: A. Ormeloxifene B. Tamoxifen C. Centchroman D. Danazol
Last Answer : . Ormeloxifen
Description : The following is an orally active ovulation inducing agent: A. Menotropin B. Mifepristone C. Danazol D. Clomiphene citrate
Last Answer : D. Clomiphene citrate
Description : Danazol produces the following side effects in premenopausal women except: A. Acne B. Menorrhagia C. Amenorrhoea D. Hot flashes
Last Answer : B. Menorrhagia
Description : Danazol is used for the following disorders except: A. Amenorrhoea B. Endometriosis C. Fibrocystic breast disease D. Precocious puberty in male children
Last Answer : A. Amenorrhoea
Description : Select the drug that primarily reduces the static component of urinary obstruction in benign hypertrophy of prostate and takes more than 3 months to exert its beneficial effect: A. Tamsulosin B. Terazosin C. Finasteride D. Amphetamine
Last Answer : C. Finasteride
Description : Select the drug which can improve urinary flow rate in benign prostatic hypertrophy without affecting prostate size: A. Amphetamine B. Prazosin C. Finasteride D. Goserelin
Last Answer : B. Prazosin
Description : Select the drug which affords faster and greater symptomatic relief in benign hypertrophy of prostate: A. Terazosin B. Desmopressin C. Finasteride D. Sildenafi
Last Answer : A. Terazosin
Description : Select the drug which affords faster and greater symptomatic relief in benign hypertrophy of prostate: A. Terazosin B. Desmopressin C. Finasteride D. Sildenafil
Description : For the treatment of hypogonadism and impotence, testosterone/dihydrotestosterone can be administered by the following route/routes: A. Oral B. Intramuscular C. Transdermal D. Both 'B' and 'C
Last Answer : D. Both 'B' and 'C'
Description : What is true about use of amphotericin B in kala azar: A. It is currently the drug of choice B. It is more effective than ketoconazole C. It is indicated only in cases not responding to sodium stibogluconate D. Both 'B' and 'C' are correct
Last Answer : D. Both 'B' and 'C' are correct
Description : The drug of choice for Kala azar is: A. Pentamidine B. Amphotericin B C. Sodium stibogluconate D. Ketoconazole
Last Answer : C. Sodium stibogluconat
Description : The following drugs are effective in systemic mycosis except: A. Terbinafine B. Itraconazole C. Ketoconazole D. Fluconazol
Last Answer : A. Terbinafine
Description : Select the drug that is fungicidal and acts by inhibiting fungal squalene epoxidase enzyme: A. Ketoconazole B. Terbinafine C. Tolnaftate D. Hamycin
Last Answer : B. Terbinafine
Description : The only azole antifungal drug which has some activity against moulds like Aspergillus is: A. Itraconazole B. Fluconazole C. Miconazole D. Ketoconazole
Last Answer : A. Itraconazole
Description : Fluconazole offers the following advantage(s) over ketoconazole: A. It is longer acting B. Its absorption from stomach is not dependent on gastric acidity C. It produces fewer side effects D. All of the above
Description : Fluconazole differs from ketoconazole in that: A. It is not active by the oral route B. It is a more potent inhibitor of drug metabolism C. It is not effective in cryptococcal meningitis D. It is unlikely to produce anti-androgenic side effects
Last Answer : D. It is unlikely to produce anti-androgenic side effects
Description : Choose the azole antifungal drug which is used only topically: A. Ketoconazole B. Fluconazole C. Itraconazole D. Econazole
Last Answer : D. Econazole
Description : Adverse effects of ketoconazole include the following except: A. Gynaecomastia B. Oligozoospermia C. Kidney damage D. Menstrual irregularities
Last Answer : C. Kidney damage
Description : Which antifungal agent is effective in both dermatophytosis as well as systemic mycosis: A. Amphotericin B B. Griseofulvin C. Clotrimazole D. Ketoconazole
Last Answer : D. Ketoconazole
Description : Select the antifungal drug which is administered only by the oral route: A. Amphotericin B B. Ketoconazole C. Griseofulvin D. Tolnaftate
Last Answer : C. Griseofulvin
Description : The drug of choice for monilial diarrhoea is: A. Flucytosine B. Nystatin C. Natamycin D. Ketoconazole
Last Answer : B. Nystatin
Description : The following prokinetic drug has been implicated in causing serious ventricular arrhythmias, particularly in patients concurrently receiving erythromycin or ketoconazole: A. Domperidone B. Cisapride C. Mosapride D. Metoclopramide
Last Answer : B. Cisapride
Description : The following second generation anti-histaminic is not likely to produce ventricular arrhythmias when administered along with ketoconazole: A. Mizolastine B. Ebastine C. Terfenadine D. Astemizole
Last Answer : A. Mizolastine
Description : Are testosterone levels related to baldness in men?
Last Answer : They must be, right? Doesn't the testosterone interact with the follicle to cause pattern baldness? Not that I obsess about this.
Description : Diethyl carbamazine citrate has the following action in filariasis: A. Rapidly kills adult filarial worms and stops production of microfilariae B. Kills circulating microfilariae C. Kills microfilariae present in nodules and serous fluids D. Promotes phagocytosis of circulating microfilariae
Last Answer : D. Promotes phagocytosis of circulating microfilaria
Description : Which fibrinolytic agent(s) selectively activate(s) fibrin bound plasminogen rather than circulating plasminogen: A. Urokinase B. Streptokinase C. Alteplase D. Both ‘A’ and ‘C
Last Answer : C. Alteplase
Description : The most likely mechanism of antihypertensive action of thiazide diuretics in the long-term is: A. Reduction of circulating blood volume B. Reduction in cardiac output C. Decreased sympathetic tone D. Reduction in total peripheral vascular resistance and improved compliance of resistance vessels
Last Answer : D. Reduction in total peripheral vascular resistance and improved compliance of resistance vessels
Description : The following allergic drug reaction is caused by circulating antibodies: A. Serum sickness B. Anaphylactic shock C. Systemic lupus erythematosus D. Angioedema
Last Answer : A. Serum sickness
Description : Choose the correct statement about anabolic steroids: A. They are testosterone congeners having anabolic but no androgenic activity B. They are androgens with relatively selective anabolic activity C. They are suitable for long-term therapy in children D. Both ‘B’ and ‘C’ are correct
Last Answer : B. They are androgens with relatively selective anabolic activity
Description : Parenteral testosterone therapy in a boy can cause the following adverse effects except: A. Gynaecomastia B. Acne C. Cholestatic jaundice D. Precocious puberty
Last Answer : C. Cholestatic jaundice
Description : Select the disorder in which methyltestosterone is beneficial but testosterone is ineffective: A. Hereditary angioneurotic edema B. Delayed puberty in a boy C. Impotence due to testicular failure D. AIDS related muscle wasting
Last Answer : A. Hereditary angioneurotic edema
Description : The following androgen does not produce cholestatic jaundice as an adverse effect: A. Testosterone propionate B. Methyl testosterone C. Fluoxymesterone D. Stanozolo
Last Answer : A. Testosterone propionate
Description : Testosterone therapy started in a boy of 8 years and continued till puberty is likely to: A. Increase adult stature B. Reduce adult stature C. Have no effect on adult stature D. Cause hypertrophy of penis
Last Answer : B. Reduce adult stature
Description : Conversion of testosterone to dihydrotestosterone by the enzyme 5α-reductase is required for the following actions except: A. Formation of male external genitalia in the foetus B. Prostatic hypertrophy in elderly males C. Pubertal changes in the male adolescent D. Spermatogenesis
Last Answer : D. Spermatogenesis
Description : Prolonged testosterone therapy can cause: A. Hypertrophy of seminiferous tubules of testes B. Hypertrophy of interstitial cells of testes C. Atrophy of interstitial cells of testes D. Both ‘A’ and ‘B’ are correct
Last Answer : C. Atrophy of interstitial cells of testes
Description : Immediate allergy reaction (type I allergic reaction) is: a) An allergic or immune response that begins within a period lasting from a few minutes to about an hour after exposure to an ... cause tissue damage e) It occurs during blood transfusion reactions and in hemolytic disease of the newborn.
Last Answer : Ans: A
Description : The following drug adverse effect is specially noted in men compared to women: A. Tardive dyskinesia due to neuroleptics B. Levodopa induced abnormal movements C. Ampicillin induced loose motions D. Ketoconazole induced loss of libido
Last Answer : D. Ketoconazole induced loss of libido
Description : Changes in GnRH pulse frequency in females is controlled by circulating levels of:
Last Answer : Changes in GnRH pulse frequency in females is controlled by circulating levels of: A. Progesterone ... C. Estrogen and inhibin D. Progesterone only
Description : Which of the following statement(s) is/are true concerning tumor necrosis factor (TNF)? a. TNF is a product of activated macrophages secreted in response to contact with endotoxin or ... completed clinical trials of anti-TNF antibody in septic patients shows a marked improvement in survival
Last Answer : Answer: a, b Tumor necrosis factor (TNF), a protein product of activated macrophages, is secreted in response to contact with endotoxin or lipopolysaccharide, antibody complexes, or ... patients utilizing infusion of monoclonal antibodies to the TNF molecule have shown no overall survival benefit
Description : Which of the following compounds is most likely to lower circulating levels of leukotrienes? (a) Zileuton (b) Montelukast (c) Carprofen (d) Aspirin (e) Allopurinol