Select the drug that antagonises diazepam action noncompetitively: A. Adenosine B. Flumazenil C. Bicuculline D. Valproic acid

Select the drug that antagonises diazepam action
noncompetitively:
A. Adenosine
B. Flumazenil
C. Bicuculline
D. Valproic acid
by

1 Answer

Answer :

C. Bicuculline
by

Related questions

Select the correct statement about flumazenil: A. It is a CNS stimulant used as an antidote for benzodiazepine poisoning B. It is a CNS depressant but blocks the action of diazepam C. It has no CNS effect of its own but blocks the depressant effects of benzodiazepines as well as barbiturates D. It has no CNS effect of its own but blocks the depressant effect of diazepam as well as stimulant effect of beta carbolines

Description : Select the correct statement about flumazenil: A. It is a CNS stimulant used as an antidote for benzodiazepine poisoning B. It is a CNS depressant but blocks the action of diazepam C. It has ... of its own but blocks the depressant effect of diazepam as well as stimulant effect of beta carbolines

Last Answer : D. It has no CNS effect of its own but blocks the depressant effect of diazepam as well as stimulant effect of beta carbolines

The following is a competitive antagonist of GABA but a noncompetitive antagonist of diazepam: A. Picrotoxin B. Muscimol C. Flumazenil D. Bicuculline

Description : The following is a competitive antagonist of GABA but a noncompetitive antagonist of diazepam: A. Picrotoxin B. Muscimol C. Flumazenil D. Bicuculline

Last Answer : D. Bicuculline

The following is a competitive antagonist of GABA but a noncompetitive antagonist of diazepam: A. Picrotoxin B. Muscimol C. Flumazenil D. Bicuculline

Description : The following is a competitive antagonist of GABA but a noncompetitive antagonist of diazepam: A. Picrotoxin B. Muscimol C. Flumazenil D. Bicuculline

Last Answer : D. Bicuculline

The following drug is used to reverse the CNS depression produced by diazepam: A. Dexamphetamine B. Doxapram C. Physostigmine D. Flumazenil

Description : The following drug is used to reverse the CNS depression produced by diazepam: A. Dexamphetamine B. Doxapram C. Physostigmine D. Flumazenil

Last Answer : D. Flumazenil

Select the drug which should not be used to treat neurotic anxiety and tension syndromes despite having antianxiety action: A. Buspirone B. Chlorpromazine C. Diazepam D. Alprazolam

Description : Select the drug which should not be used to treat neurotic anxiety and tension syndromes despite having antianxiety action: A. Buspirone B. Chlorpromazine C. Diazepam D. Alprazolam

Last Answer : B. Chlorpromazine

Piperazine antagonises the anthelmintic action of the following drug: A. Pyrantel pamoate B. Mebendazole C. Albendazole D. Niclosamide

Description : Piperazine antagonises the anthelmintic action of the following drug: A. Pyrantel pamoate B. Mebendazole C. Albendazole D. Niclosamide

Last Answer : A. Pyrantel pamoate

Choose the drug that has been found to be more selective for the ω1 subtype of BZD receptor, and produces hypnotic action but little antianxiety, muscle relaxant or anticonvulsant actions: A. Zopiclone B. Zolpidem C. Flumazenil D. Melatonin

Description : Choose the drug that has been found to be more selective for the ω1 subtype of BZD receptor, and produces hypnotic action but little antianxiety, muscle relaxant or anticonvulsant actions: A. Zopiclone B. Zolpidem C. Flumazenil D. Melatonin

Last Answer : B. Zolpidem

Select the correct statement about benzodiazepines (BZDs): A. All BZDs facilitate GABA mediated Cl¯ influx into neurones B. Different BZDs exert the same degrees of hypnotic, anxiolytic and anticonvulsant actions C. The BZD receptor is homogeneous at all neuronal sites D. The muscle relaxant action of BZDs is not blocked by flumazenil

Description : Select the correct statement about benzodiazepines (BZDs): A. All BZDs facilitate GABA mediated Cl¯ influx into neurones B. Different BZDs exert the same degrees of hypnotic, anxiolytic and anticonvulsant ... at all neuronal sites D. The muscle relaxant action of BZDs is not blocked by flumazenil

Last Answer : A. All BZDs facilitate GABA mediated Cl¯ influx into neurones

A manic patient has been brought to the hospital with nonstop talking, singing, uncontrolable behaviour and apparent loss of contact with reality. Which of the following is the most appropriate drug for rapid control of his symptoms: A. Lithium carbonate B. Phenobarbitone C. Haloperidol D. Valproic acid

Description : A manic patient has been brought to the hospital with nonstop talking, singing, uncontrolable behaviour and apparent loss of contact with reality. Which of the following is the most appropriate drug ... control of his symptoms: A. Lithium carbonate B. Phenobarbitone C. Haloperidol D. Valproic acid

Last Answer : C. Haloperidol

The drug of choice for trigeminal neuralgia is: A. Aspirin B. Imipramine C. Carbamazepine D. Valproic acid

Description : The drug of choice for trigeminal neuralgia is: A. Aspirin B. Imipramine C. Carbamazepine D. Valproic acid

Last Answer : C. Carbamazepine

The following antiepileptic drug is most likely to impair learning and memory, and produce behavioral abnormalities in children: A. Valproic acid B. Phenobarbitone C. Phenytoin D. Ethosuximide

Description : The following antiepileptic drug is most likely to impair learning and memory, and produce behavioral abnormalities in children: A. Valproic acid B. Phenobarbitone C. Phenytoin D. Ethosuximide

Last Answer : B. Phenobarbitone

That sulfonamides act by inhibiting folate synthesis in bacteria is supported by the following findings except: A. Paraaminobenzoic acid antagonises the action of sulfonamides B. Methionine antagonises the action of sulfonamides C. Purines and thymidine present in pus antagonise the action of sulfonamides D. Bacteria that utilise folic acid taken up from the medium are insensitive to sulfonamides

Description : That sulfonamides act by inhibiting folate synthesis in bacteria is supported by the following findings except: A. Paraaminobenzoic acid antagonises the action of sulfonamides B. Methionine antagonises ... . Bacteria that utilise folic acid taken up from the medium are insensitive to sulfonamides

Last Answer : B. Methionine antagonises the action of sulfonamides

The following drug has been used to stimulate respiratory and vasomotor centres as an expedient measure, because it has the least propensity to induce convulsions: A. Pentylenetetrazole B. Doxapram C. Bicuculline D. Amphetamine

Description : The following drug has been used to stimulate respiratory and vasomotor centres as an expedient measure, because it has the least propensity to induce convulsions: A. Pentylenetetrazole B. Doxapram C. Bicuculline D. Amphetamine

Last Answer : B. Doxapram

Choose the correct statement about amiloride: A. It antagonises the action of aldosterone B. It can be used to treat lithium induced diabetes insipidus C. It increases calcium loss in urine D. It is dose to dose less potent than triamterene

Description : Choose the correct statement about amiloride: A. It antagonises the action of aldosterone B. It can be used to treat lithium induced diabetes insipidus C. It increases calcium loss in urine D. It is dose to dose less potent than triamterene

Last Answer : B. It can be used to treat lithium induced diabetes insipidus

Nalorphine is nearly equipotent analgesic as morphine, but is not used clinically as an analgesic because: A. It causes more marked respiratory depression B. It has higher abuse potential C. It antagonises the action of morphine D. It produces prominent dysphoric effects

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Last Answer : D. It produces prominent dysphoric effects

The following drugs exert their action through the GABAA-benzodiazepine–receptor Cl¯ channel complex except: A. Baclofen B. Zolpidem C. Bicuculline D. Phenobarbitone

Description : The following drugs exert their action through the GABAA-benzodiazepine–receptor Cl¯ channel complex except: A. Baclofen B. Zolpidem C. Bicuculline D. Phenobarbitone

Last Answer : A. Baclofen

The following drug is not likely to produce dependence: A. Diazepam B. Chlorpromazine C. Pethidine D. Methadone

Description : The following drug is not likely to produce dependence: A. Diazepam B. Chlorpromazine C. Pethidine D. Methadone

Last Answer : B. Chlorpromazine

The preferred drug for status epilepticus is: A. Intravenous diazepam B. Intravenous phenytoin sodium C. Intramuscular phenobarbitone D. Rectal diazepam

Description : The preferred drug for status epilepticus is: A. Intravenous diazepam B. Intravenous phenytoin sodium C. Intramuscular phenobarbitone D. Rectal diazepam

Last Answer : A. Intravenous diazepam

A 3-year-old boy gets seizures whenever he develops fever. Which is the most appropriate strategy so that he does not develop febrile convulsions: A. Treat fever with paracetamol and do not give any anticonvulsant drug B. Continuous phenobarbitone prophylaxis till the age of 10 years C. Continuous diazepam prophylaxis for 3 years D. Intermittent diazepam prophylaxis started at the onset of fever

Description : A 3-year-old boy gets seizures whenever he develops fever. Which is the most appropriate strategy so that he does not develop febrile convulsions: A. Treat fever with paracetamol and ... Continuous diazepam prophylaxis for 3 years D. Intermittent diazepam prophylaxis started at the onset of fever

Last Answer : D. Intermittent diazepam prophylaxis started at the onset of fever

The preferred drug for suppressing febrile convulsions is: A. Intramuscular phenobarbitone B. Intravenous phenytoin C. Rectal diazepam D. Oral sodium valproate

Description : The preferred drug for suppressing febrile convulsions is: A. Intramuscular phenobarbitone B. Intravenous phenytoin C. Rectal diazepam D. Oral sodium valproate

Last Answer : C. Rectal diazepam

The drug used for controlling tetany is: A. Intravenous diazepam B. Intramuscular vitamin D C. Intravenous calcium gluconate D. Intravenous calcitonin

Description : The drug used for controlling tetany is: A. Intravenous diazepam B. Intramuscular vitamin D C. Intravenous calcium gluconate D. Intravenous calcitonin

Last Answer : C. Intravenous calcium gluconate

Select the anaesthetic that increases cardiac output and blood pressure: A. Halothane B. Fentanyl C. Ketamine D. Diazepam

Description : Select the anaesthetic that increases cardiac output and blood pressure: A. Halothane B. Fentanyl C. Ketamine D. Diazepam

Last Answer : C. Ketamine

The following drug terminates paroxysmal supraventricular tachycardia rapidly, but cannot be used to prevent its recurrences: A. Verapamil B. Adenosine C. Propranolol D. Digoxin

Description : The following drug terminates paroxysmal supraventricular tachycardia rapidly, but cannot be used to prevent its recurrences: A. Verapamil B. Adenosine C. Propranolol D. Digoxin

Last Answer : B. Adenosine

Ethanol is used in methanol poisoning because it: A. Antagonises the actions of methanol B. Stimulates the metabolism of methanol and reduces its blood level C. Inhibits the metabolism of methanol and generation of toxic metabolite D. Replenishes the folate stores depleted by methano

Description : Ethanol is used in methanol poisoning because it: A. Antagonises the actions of methanol B. Stimulates the metabolism of methanol and reduces its blood level C. Inhibits the metabolism of methanol and generation of toxic metabolite D. Replenishes the folate stores depleted by methano

Last Answer : C. Inhibits the metabolism of methanol and generation of toxic metabolite

The GABAB receptor: A. Is an intrinsic ion channel containing receptor B. Mediates neuronal depolarization C. Is insensitive to blockade by bicuculline D. Regulates intracellular cAMP

Description : The GABAB receptor: A. Is an intrinsic ion channel containing receptor B. Mediates neuronal depolarization C. Is insensitive to blockade by bicuculline D. Regulates intracellular cAMP

Last Answer : C. Is insensitive to blockade by bicuculline

The following statement(s) is/are correct in relation to diazepam and chlorpromazine: A. Both have anticonvulsant property B. Both do not carry abuse liability C. Both have antianxiety action D. All of the above are correc

Description : The following statement(s) is/are correct in relation to diazepam and chlorpromazine: A. Both have anticonvulsant property B. Both do not carry abuse liability C. Both have antianxiety action D. All of the above are correc

Last Answer : C. Both have antianxiety action

Despite having anticonvulsant action, diazepam is not used in the treatment of epilepsy because: A. It is not effective orally B. It causes sedation C. Its anticonvulsant action wanes off with chronic use D. Both ‘B’ and ‘C’ are correct

Description : Despite having anticonvulsant action, diazepam is not used in the treatment of epilepsy because: A. It is not effective orally B. It causes sedation C. Its anticonvulsant action wanes off with chronic use D. Both ‘B’ and ‘C’ are correct

Last Answer : D. Both ‘B’ and ‘C’ are correct

Zolpidem differs from diazepam in that: A. It is safer in overdose than diazepam B. Its hypnotic action shows little fading on repeated nightly use C. It causes more marked suppression of REM sleep D. It has more potent muscle relaxant action

Description : Zolpidem differs from diazepam in that: A. It is safer in overdose than diazepam B. Its hypnotic action shows little fading on repeated nightly use C. It causes more marked suppression of REM sleep D. It has more potent muscle relaxant action

Last Answer : B. Its hypnotic action shows little fading on repeated nightly use

Hypnotic dose of diazepam produces the following action: A. Tachycardia B. Constipation C. Hyperalgesia D. Decreased nocturnal gastric secretion

Description : Hypnotic dose of diazepam produces the following action: A. Tachycardia B. Constipation C. Hyperalgesia D. Decreased nocturnal gastric secretion

Last Answer : D. Decreased nocturnal gastric secretion

Use of adenosine for terminating an episode of paroxysmal supraventricular tachycardia has the following advantages except: A. It does not produce any side effect B. It can be given to patients with low blood pressure C. Its action lasts less than 1 min after bolus intravenous injection D. It is effective in patients not responding to verapamil

Description : Use of adenosine for terminating an episode of paroxysmal supraventricular tachycardia has the following advantages except: A. It does not produce any side effect B. It can be given to patients ... 1 min after bolus intravenous injection D. It is effective in patients not responding to verapamil

Last Answer : A. It does not produce any side effect

The primary mechanism of action of benzodiazepines is: A. Dopamine antagonism B. Adenosine antagonism C. Opening of neuronal chloride channels D. Facilitation of GABA-mediated chloride influx

Description : The primary mechanism of action of benzodiazepines is: A. Dopamine antagonism B. Adenosine antagonism C. Opening of neuronal chloride channels D. Facilitation of GABA-mediated chloride influx

Last Answer : D. Facilitation of GABA-mediated chloride influx

Methylxanthines exert the following action(s) at cellular/molecular level: A. Intracellular release of Ca2+ B. Antagonism of adenosine C. Inhibition of phosphodiesterase D. All of the above

Description : Methylxanthines exert the following action(s) at cellular/molecular level: A. Intracellular release of Ca2+ B. Antagonism of adenosine C. Inhibition of phosphodiesterase D. All of the above

Last Answer : D. All of the above

Select the drug which can markedly potentiate the vasodilator action of organic nitrates: A. Propranolol B. Fluoxetine C. Hydrochlorothiazide D. Sildenafil

Description : Select the drug which can markedly potentiate the vasodilator action of organic nitrates: A. Propranolol B. Fluoxetine C. Hydrochlorothiazide D. Sildenafil

Last Answer : D. Sildenafil

What is NOT TRUE in relation to the prescription of 5mg or 10mg of diazepam for sedation?check A. Patient commonly complain of post operative headache T B. An acceptable level of anxiolytic action is obtained when the drug is given one hour preoperatively T C. There is a profound amnesic action and no side affects not sure D. Active metabolites can give a level of sedation up to 8 hours post operatively T E. As Benzodiazepine the action can be reversed with FlumazepilNE T

Description : What is NOT TRUE in relation to the prescription of 5mg or 10mg of diazepam for sedation?check A. Patient commonly complain of post operative headache T B. An acceptable level of anxiolytic ... to 8 hours post operatively T E. As Benzodiazepine the action can be reversed with FlumazepilNE T

Last Answer : C. There is a profound amnesic action and no side affects not sure

Which of the following is an orally active drug that blocks sodium channels and decreases action potential duration? (a) Adenosine (b) Amiodarone (c) Disopyramide (d) Esmolol (e) Mexiletine

Description : Which of the following is an orally active drug that blocks sodium channels and decreases action potential duration? (a) Adenosine (b) Amiodarone (c) Disopyramide (d) Esmolol (e) Mexiletine

Last Answer : Ans: E

Select the antimicrobial drug which is used orally only for urinary tract infection or for bacterial diarrhoeas: A. Nalidixic acid B. Azithromycin C. Bacampicillin D. Pefloxacin

Description : Select the antimicrobial drug which is used orally only for urinary tract infection or for bacterial diarrhoeas: A. Nalidixic acid B. Azithromycin C. Bacampicillin D. Pefloxacin

Last Answer : A. Nalidixic acid

Select the drug combination which does not exhibit supraadditive synergism: A. Nalidixic acid + Nitrofurantoin B. Amoxicillin + Clavulanic acid C. Pyrimethamine + Sulfadoxine D. Sulfamethoxazole + Trimethoprim

Description : Select the drug combination which does not exhibit supraadditive synergism: A. Nalidixic acid + Nitrofurantoin B. Amoxicillin + Clavulanic acid C. Pyrimethamine + Sulfadoxine D. Sulfamethoxazole + Trimethoprim

Last Answer : A. Nalidixic acid + Nitrofurantoin

Select the first line hypolipidemic drug/drugs for treating hypertriglyceridemia in a subject with normal cholesterol level: A. Fibrates B. HMG-CoA reductase inhibitors C. Nicotinic acid D. Both 'A' and 'C' are correc

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Last Answer : D. Both 'A' and 'C' are correct

Select the hypolipidemic drug that enhances lipoprotein synthesis, fatty acid oxidation and LDLreceptor expression in liver through paroxisome proliferator-activated receptor α: A. Lovastatin B. Atorvastatin C. Bezafibrate D. Nicotinic acid

Description : Select the hypolipidemic drug that enhances lipoprotein synthesis, fatty acid oxidation and LDLreceptor expression in liver through paroxisome proliferator-activated receptor α: A. Lovastatin B. Atorvastatin C. Bezafibrate D. Nicotinic acid

Last Answer : C. Bezafibrate

Select the drug which reduces cholesterol synthesis in liver, increases expression of LDL receptors on hepatocytes and has been found to reduce mortality due to coronary artery disease: A. Simvastatin B. Nicotinic acid C. Gemfibrozil D. Colestipol (p. 577, 578) 43.1 4 3 . 1 D 43.2 4 3 . 2 C 43.3 4 3 . 3 A 43.4 4 3 . 4 A Ai

Description : Select the drug which reduces cholesterol synthesis in liver, increases expression of LDL receptors on hepatocytes and has been found to reduce mortality due to coronary artery disease: A. Simvastatin B. Nicotinic acid C. Gemfibrozil D. Colestipol (

Last Answer : A. Simvastatin

Select the most appropriate hypolipidemic drug for a patient with raised LDL-cholesterol level but normal triglyceride level: A. A HMG-CoA reductase inhibitor B. A fibric acid derivative C. Gugulipid D. Nicotinic acid

Description : Select the most appropriate hypolipidemic drug for a patient with raised LDL-cholesterol level but normal triglyceride level: A. A HMG-CoA reductase inhibitor B. A fibric acid derivative C. Gugulipid D. Nicotinic acid

Last Answer : A. A HMG-CoA reductase inhibitor

Select the drug that may improve myocardial tolerance to ischaemia and reduce anginal attacks without altering heart rate, blood pressure or myocardial O2 consumption: A. Trimetazidine B. Nicorandil C. Dipyridamole D. Nicotinic acid

Description : Select the drug that may improve myocardial tolerance to ischaemia and reduce anginal attacks without altering heart rate, blood pressure or myocardial O2 consumption: A. Trimetazidine B. Nicorandil C. Dipyridamole D. Nicotinic acid

Last Answer : A. Trimetazidine

Select the drug which inhibits cyclooxygenase in the brain but not at peripheral sites of inflammation: A. Nimesulide B. Paracetamol C. Ketorolac D. Mephenamic acid

Description : Select the drug which inhibits cyclooxygenase in the brain but not at peripheral sites of inflammation: A. Nimesulide B. Paracetamol C. Ketorolac D. Mephenamic acid

Last Answer : B. Paracetamol

Drugs effective in bipolar illness include the following except: A. Olanzapine B. Diazepam C. Sodium valproate D. Lamotrigine

Description : Drugs effective in bipolar illness include the following except: A. Olanzapine B. Diazepam C. Sodium valproate D. Lamotrigine

Last Answer : B. Diazepam

Diabetic and other types of neuropathic pain often responds to: A. Chlorpromazine B. Diazepam C. Imipramine D. Lithium

Description : Diabetic and other types of neuropathic pain often responds to: A. Chlorpromazine B. Diazepam C. Imipramine D. Lithium

Last Answer : C. Imipramine

Diazepam is indicated in the following conditions except: A. Generalized tonic-clonic (grand mal) epilepsy B. Tetanus C. Febrile convulsions D. Cardiac catheterization

Description : Diazepam is indicated in the following conditions except: A. Generalized tonic-clonic (grand mal) epilepsy B. Tetanus C. Febrile convulsions D. Cardiac catheterization

Last Answer : A. Generalized tonic-clonic (grand mal) epilepsy

At a single hypnotic dose, the pharmacokinetics of diazepam is characterised by: A. Slow elimination and little redistribution B. Slow elimination with marked redistribution C. Rapid elimination and marked redistribution D. Ultra rapid elimination

Description : At a single hypnotic dose, the pharmacokinetics of diazepam is characterised by: A. Slow elimination and little redistribution B. Slow elimination with marked redistribution C. Rapid elimination and marked redistribution D. Ultra rapid elimination

Last Answer : B. Slow elimination with marked redistribution

Residual CNS depression is least marked after the use of the following anaesthetic: A. Diazepam B. Thiopentone sodium C. Lorazepam D. Propofo

Description : Residual CNS depression is least marked after the use of the following anaesthetic: A. Diazepam B. Thiopentone sodium C. Lorazepam D. Propofo

Last Answer : D. Propofol

Diazepam is used as a muscle relaxant for: A. Deep intra-abdominal operation B. Tracheal intubation C. Tetanus D. Diagnosis of myasthenia gravis

Description : Diazepam is used as a muscle relaxant for: A. Deep intra-abdominal operation B. Tracheal intubation C. Tetanus D. Diagnosis of myasthenia gravis

Last Answer : C. Tetanus

Which of the following drugs exhibits ‘therapeutic window’ phenomenon: A. Captopril B. Furosemide C. Diazepam D. Imipramine

Description : Which of the following drugs exhibits ‘therapeutic window’ phenomenon: A. Captopril B. Furosemide C. Diazepam D. Imipramine

Last Answer : D. Imipramine