The following opioid analgesic is similar to codeine in
pharmacological profile but is less constipating:
A. Methadone
B. Buprenorphine
C. Butorphanol
D. Dextropropoxyphene

1 Answer

Answer :

D. Dextropropoxyphene

Related questions

Description : Which of the following opioid analgesics is similar to codeine in pharmacological profile but is less constipating ? (a) Methadone (b) Buprenorphine (c) Butorphanol (d) Dextropropoxyphene

Last Answer : Ans: D

Description : Select the opioid analgesic which acts primarily through κ (kappa) opioid receptor: A. Pentazocine B. Methadone C. Buprenorphine D. Pethidine

Last Answer : A. Pentazocine

Description : Select the analgesic which acts through opioid as well as additional spinal monoaminergic mechanisms: A. Tramadol B. Ethoheptazine C. Dextropropoxyphene D. Alfentanil

Last Answer : A. Tramado

Description : The following is true of buprenorphine: A. It is an agonist-antagonist type of opioid analgesic B. Its subjective effects are different from those of morphine C. Naloxone is largely ineffective in reversing its effects D. It produces mydriasis

Last Answer : C. Naloxone is largely ineffective in reversing its effects

Description : Which of the following is an agonist-antagonist type of opioid analgesic: A. Pethidine B. Pentazocine C. Fentanyl D. Buprenorphine

Last Answer : B. Pentazocine

Description : The following opioids are κ (kappa) receptor analgesics except: A. Buprenorphine B. Butorphanol C. Nalbuphine D. Pentazocine

Last Answer : A. Buprenorphine

Description : Which of the following is an agonistantagonist type of opioid analgesic (a) Pethidine (b) Pentazocine (c) Fentanyl (d) Buprenorphine

Last Answer : Ans: B

Description : The following opioid is more potent than morphine: A. Pethidine B. Fentanyl C. Dextropropoxyphene D. Tramadol

Last Answer : B. Fentanyl

Description : Choose the correct statement about codeine: A. It has a lower oral: parenteral activity ratio than morphine B. It is devoid of abuse liability C. It is a weaker analgesic than morphine D. It is a more potent antitussive than morphine

Last Answer : C. It is a weaker analgesic than morphine

Description : An opioid analgesic is preferred over aspirin like analgesic in the following condition: A. Acute gout B. Burn C. Toothache D. Neuralgi

Last Answer : B. Burn

Description : Indicate the opioid analgesic that is used as transdermal patch for chronic and cancer pain: A. Morphine B. Pentazocine C. Fentanyl D. Tramadol

Last Answer : The distinctive feature(s) of methadone compared to morphine is/are: A. High oral bioavailability B. High plasma protein and tissue binding C. Delayed and milder withdrawal symptoms in dependent subjects D. All of the above

Description : Apraclonidine is a clonidine congener which is used: A. To suppress opioid withdrawal syndrome B. To suppress menopausal syndrome C. As Analgesic D. To reduce intraocular tension

Last Answer : D. To reduce intraocular tension

Description : Choose the correct statement about nefopam: A. It is a nonopioid analgesic which does not inhibit prostaglandin synthesis B. It is an orally active opioid analgesic C. It is an analgesic with potent antiinflammatory activity D. It is a preferential COX-2 inhibitor

Last Answer : A. It is a nonopioid analgesic which does not inhibit prostaglandin synthesis

Description : Apraclonidine is a clonidine congener which is used: A. To suppress opioid withdrawal syndrome B. To suppress menopausal syndrome C. As Analgesic D. To reduce intraocular tension

Last Answer : D. To reduce intraocular tension

Description : The main advantage of ketorolac over aspirin is that ketorolac (a) Can be combined more safely with an opioid such as codeine (b) Can be obtained as an over-the-counter agent (c) Does not ... (e) Is less likely to cause acute renal failure in patients with some preexisting degree of renal impairment

Last Answer : Ans: D

Description : This drug, which does not activate opioid receptors, has been proposed as a maintenance drug in treatment programs for opioid addicts; a singly oral dose will block the effects of injected heroin for up to 48 hours (a) Amphetamine (b) Buprenorphine (c) Naloxone (d) Naltrexone (e) Propoxyphene

Last Answer : Ans: D

Description : The following is true of pethidine except: A. At equianalgesic doses it causes less respiratory depression than morphine B. It is less constipating than morphine C. It is a poor antitussive D. In overdose it often produces excitatory effect

Last Answer : A. At equianalgesic doses it causes less respiratory depression than morph

Description : Select the analgesic which acts through opioids as well as additional spinal monoaminergic mechanisms. (a) Tramadol (b) Ethoheptazine (c) Dextropropoxyphene (d) Alfentanil

Last Answer : Ans: A

Description : Which of the following antitussive is present in opium but has no analgesic or addicting properties ? (a) Noscapine (b) Codeine (c) Pholcodeine (d) Ethylmorphine

Last Answer : Ans: A

Description : The following antitussive is present in opium but has no analgesic or addicting properties: A. Noscapine B. Codeine C. Pholcodeine D. Ethylmorphine

Last Answer : A. Noscapine

Description : What is true of tolerance occurring in regular opium abusers: A. Tolerance develops to all actions of morphine B. No tolerance occurs to euphoric and sedative actions of morphine C. No ... to constipating and miotic actions of morphine D. Lethal dose of morphine is not significantly increased

Last Answer : C. No tolerance occurs to constipating and miotic actions of morphine

Description : Codeine is used clinically as: A. Analgesic B. Antitussive C. Antidiarrhoeal D. All of the above

Last Answer : D. All of the above

Description : An opioid analgesic is preferred over aspirin like analgesic in the following condition. (a) Acute gout (b) Burn (c) Toothache (d) Neuralgia

Last Answer : Ans: B

Description : The distinctive feature(s) of methadone compared to morphine is/are: A. High oral bioavailability B. High plasma protein and tissue binding C. Delayed and milder withdrawal symptoms in dependent subjects D. All of the above

Last Answer : D. All of the above

Description : The following drug is not likely to produce dependence: A. Diazepam B. Chlorpromazine C. Pethidine D. Methadone

Last Answer : B. Chlorpromazine

Description : Select the drug that has been found to reduce alcohol craving and chances of resumed heavy drinking by alcoholics after they have undergone a detoxification programme: A. Chlordiazepoxide B. Chlorpromazine C. Methadone D. Naltrexone

Last Answer : D. Naltrexone

Description : Ganglion blocking drugs are no longer used in therapeutics because: A. They have few and weak pharmacological actions B. They produce many side effects C. They are inactive by oral route D. They have short duration of action

Last Answer : A. They have potent antiovulatory action of their own

Description : Ganglion blocking drugs are no longer used in therapeutics because: A. They have few and weak pharmacological actions B. They produce many side effects C. They are inactive by oral route D. They have short duration of action

Last Answer : B. They produce many side effects

Description : The following is not true of the cytochrome P450 isoenzyme CYP2D6: A. It generates the hepatotoxic metabolite N-acetyl benzoquinone immine from paracetamol B. It is involved in demethylation of ... for poor capacity to hydroxylate many drugs including metoprolol D. It is inhibited by quinidine

Last Answer : A. It generates the hepatotoxic metabolite N-acetyl benzoquinone immine from paracetamol

Description : Concurrent administration of aspirin interacts unfavourably with the following drugs except: A. Furosemide B. Spironolactone C. Codeine D. Methotrexate

Last Answer : C. Codeine

Description : The following is true of loperamide except: A. It is absorbed from intestines and exerts centrally mediated antidiarrhoeal action B. It acts on the opioid receptors in the gut C. It increases ... of the intestines D. It inhibits intestinal secretion by binding to calmodulin in the mucosal cells

Last Answer : A. It is absorbed from intestines and exerts centrally mediated antidiarrhoeal action

Description : 4 Choose the correct statement about the role of opioid antimotility drugs in the management of diarrhoeas: A. They are used to control diarrhoea irrespective of its etiology B. They should ... antimicrobial therapy of diarrhoea D. They are the drugs of choice in irritable bowel syndrome diarrhoea

Last Answer : B. They should be used only as a short-term measure after ensuring that enteroinvasive organisms are not involved

Description : The opioid antidiarrhoeal drugs act by the following mechanism(s): A. They relax the intestinal smooth muscle B. They inhibit intestinal peristalsis C. They promote clearance of intestinal pathogens Aim4aiims.in D. All of the above

Last Answer : B. They inhibit intestinal peristalsis

Description : The following statement is true about endogenous opioid peptides: A. They activate only μ opioid recepors B. They do not occur in peripheral tissues C. They mediate stress induced analgesia D. Naloxone fails to antagonise their actio

Last Answer : C. They mediate stress induced analgesia

Description : Select the opioid antagonist that is preferred for long term opioid blockade therapy of post addicts: A. Nalorphine B. Naloxone C. Naltrexone D. Nalbuphine

Last Answer : C. Naltrexone

Description : Select the correct statement about Naloxone: A. It equally blocks μ, κ and δ opioid receptors B. It blocks μ receptors at lower doses than those needed for others C. It blocks κ receptors at lower doses than those needed for others D. It blocks δ receptors at lower doses than those needed for others

Last Answer : B. It blocks μ receptors at lower doses than those needed for others

Description : The following are pure opioid antagonists except: A. Nalmfene B. Nalbuphine C. Naloxone D. Naltrexone

Last Answer : B. Nalbuphine

Description : Features of µ (Mu) opioid receptor include the following except: A. Acts by inhibiting cAMP formation B. Mediates miotic action C. Mediates low ceiling respiratory depression D. Mediates high ceiling supraspinal analgesia

Last Answer : C. Mediates low ceiling respiratory depression

Description : Morphine has high affinity for the following opioid receptor(s): A. μ (Mu) B. κ (Kappa) C. δ (Delta) D. All of the above

Last Answer : A. μ (Mu

Description : Select the receptor that is located intracellularly: A. Opioid μ receptor B. Steroid receptor C. Prostaglandin receptor D. Angiotensin receptor

Last Answer : B. Steroid receptor

Description : The most important receptor involved in cytotoxic drug induced vomiting is: A. Histamine H1 receptor B. Serotonin 5-HT3 receptor C. Dopamine D2 receptor D. Opioid μ receptor

Last Answer : B. Serotonin

Description : Nalorphine is nearly equipotent analgesic as morphine, but is not used clinically as an analgesic because: A. It causes more marked respiratory depression B. It has higher abuse potential C. It antagonises the action of morphine D. It produces prominent dysphoric effects

Last Answer : D. It produces prominent dysphoric effects

Description : Pentazocine differs from morphine in that: A. It is inactive by the oral route B. It does not produce physical dependence C. It has a lower ceiling of analgesic effect D. Its action is not blocked by naloxone

Last Answer : C. It has a lower ceiling of analgesic effec

Description : The following is not true of morphine: A. Its 2-glucuronide metabolite is an active analgesic B. Its active metabolite penetrates blood-brain barrier better than morphine C. Its oral: parenteral activity ratio is 1:4 D. It undergoes enterohepatic cycling

Last Answer : B. Its active metabolite penetrates blood-brain barrier better than morphine

Description : Barbiturates exert the following actions except: A. Anticonvulsant B. Analgesic C. Antianxiety D. Respiratory depressant

Last Answer : B. Analgesic

Description : s a general anaesthetic, halothane has the following advantages except: A. Very good analgesic action B. Noninflammable and nonexplosive C. Reasonably rapid induction of anaesthesia D. Pleasant and nonirritating

Last Answer : A. Very good analgesic action

Description : Select the correct statement about nitrous oxide: A. It irritates the respiratory mucosa B. It has poor analgesic action C. It is primarily used as a carrier and adjuvant to other anaesthetics D. It frequently induces post anaesthetic nausea and retching

Last Answer : C. It is primarily used as a carrier and adjuvant to other anaesthetics

Description : Sustained/controlled release oral dosage form is appropriate for the following type of drug: A. An antiarthritic with a plasma half life of 24 hr B. A sleep inducing hypnotic with a plasma half life of ... 3 hours D. An analgesic with a plasma half life of 6 hours used for relief of casual headache

Last Answer : C. An antihypertensive with a plasma half life of 3 hours

Description : The following antiinflammatory analgesic has been cleared for pediatric use: A. Indomethacin B. Ibuprofen C. Ketorolac D. Piroxicam

Last Answer : B. Ibuprofen

Description : For a patient of peptic ulcer, the safest nonopioid analgesic is: A. Celecoxib B. Diclofenac sodium C. Paracetamol D. Ibuprofen

Last Answer : C. Paracetamol