The following is not true of the cytochrome P450
isoenzyme CYP2D6:
A. It generates the hepatotoxic metabolite N-acetyl
benzoquinone immine from paracetamol
B. It is involved in demethylation of codeine into
morphine
C. Its altered form is responsible for poor capacity to
hydroxylate many drugs including metoprolol
D. It is inhibited by quinidine
isoenzyme CYP2D6:
A. It generates the hepatotoxic metabolite N-acetyl
benzoquinone immine from paracetamol
B. It is involved in demethylation of codeine into
morphine
C. Its altered form is responsible for poor capacity to
hydroxylate many drugs including metoprolol
D. It is inhibited by quinidine