Description : Antiatherosclerotic effect of which class of hypolipidemic drugs may involve additional mechanisms like improved endothelial function, reduced LDL oxidation and antiinflammatory property: A. Bile acid sequestrant resins B. Statins C. Fibrates D. Nicotinic acid
Last Answer : B. Statins
Description : As a plasma expander, dextran has the following advantages except: A. It exerts oncotic pressure similar to plasma proteins B. It keeps plasma volume expanded for about 24 hours C. It is nonpyrogenic D. It does not interfere with grouping and cross matching of blood
Last Answer : D. It does not interfere with grouping and cross matching of blood
Description : The following is true of heparin except: A. Sudden stoppage of continuous heparin therapy causes rebound increase in blood coagulability B. High doses of heparin inhibit platelet aggregation ... active circulating anticoagulant D. Heparin clears lipemic plasma in vivo but not in vitro
Last Answer : C. Heparin is the physiologically active circulating anticoagulant
Description : The homopo lysacchar ide used for intravenous infusion as plasma substitute is (A) Agar (B) Inulin (C) Pectin (D) Starch
Last Answer : A
Description : Which of the following colloids is expensive but rapidly expands plasma volume? a) Albumin Albumin is a colloid that requires human donors, is limited in supply, and can cause congestive heart failure ... , not a colloid. d) Hypertonic Saline Hypertonic saline is a crystalloid, not a colloid.
Last Answer : a) Albumin Albumin is a colloid that requires human donors, is limited in supply, and can cause congestive heart failure.
Description : The termination of heparin activity by protamine sulfate is due to (a) A chelating action (b) The inhibition of gastrointestinal absorption of heparin (c) The displacement of heparin-plasma protein binding (d) An acid-base interaction (e) The prothrombin-like activity of protamine
Last Answer : Ans: D
Description : Choose the drug which alters surface receptors on platelet membrane to inhibit aggregation, release reaction and to improve platelet survival in extracorporeal circulation: A. Dipyridamole B. Ticlopidine C. Aspirin D. Heparin
Last Answer : B. Ticlopidine
Description : The most effective drug for prevention of stroke in atrial fibrillation patients is: A. Aspirin B. Warfarin C. Low dose subcutaneous heparin D. Digoxin
Last Answer : B. Warfarin
Description : The following can be used to antagonise the action of heparin in case of overdose: A. Heparan sulfate B. Dextran sulfate C. Protamine sulfate D. Ancrod
Last Answer : C. Protamine sulfate
Description : Heparin is contraindicated in patients suffering from the following diseases except: A. Pulmonary tuberculosis B. Bleeding due to defibrination syndrome C. Subacute bacterial endoc
Last Answer : B. Bleeding due to defibrination syndrome
Description : Low dose subcutaneous heparin therapy is indicated for: A. Prevention of leg vein thrombosis in elderly patients undergoing abdominal surgery B. Ischaemic stroke C. Patients undergoing neurosurgery D. Prevention of extention of coronary artery thrombus in acute myocardial infarction
Last Answer : A. Prevention of leg vein thrombosis in eld
Description : Low molecular weight heparins have the following advantages over unfractionated heparin except: A. Higher efficacy in arterial thrombosis B. Less frequent dosing C. Higher and more consistent subcutaneous bioavailability D. Laboratory monitoring of response not required
Last Answer : A. Higher efficacy in arterial thrombosis
Description : Low molecular weight heparins differ from unfractionated heparin in that: A. They selectively inhibit factor Xa B. They do not significantly prolong clotting time C. They are metabolized slowly and have longer duration of action D. All of the above are correct
Last Answer : D. All of the above are correct
Description : The following action(s) of heparin is/are essential for inhibition of factor Xa: A. Facilitation of antithrombin III mediated inhibition of factor XIIa B. Provision of scaffold for the clotting factor ... configurational change in antithrombin III to expose its interacting sites D. Both A' and B
Last Answer : C. Induction of a configurational change in antithrombin III to expose its interacting sites
Description : Low doses of heparin prolong: A. Bleeding time B. Activated partial thromboplastin time C. Prothrombin time D. Both ‘B’ and ‘C’
Last Answer : B. Activated partial thromboplastin time
Description : Low concentrations of heparin selectively interfere with the following coagulation pathway(s): A. Intrinsic pathway B. Extrinsic pathway C. Common pathway D. Both ‘A’ and ‘C’
Last Answer : A. Intrinsic pathway
Description : he primary mechanism by which heparin prevents coagulation of blood is: A. Direct inhibition of prothrombin to thrombin conversion B. Facilitation of antithrombin III mediated inhibition of factor Xa and ... of antithrombin III to inhibit factors IX and XI D. Inhibition of factors XIIa and XIIIa
Last Answer : B. Facilitation of antithrombin III mediated inhibition of factor Xa and thrombi
Description : Vitamin K is indicated for the treatment of bleeding occurring in patients: A. Being treated with heparin B. Being treated with streptokinase C. Of obstructive jaundice D. Of peptic ulcer
Last Answer : C. Of obstructive jaundice
Description : Select the hypocholesterolemic drug which interferes with intestinal absorption of bile salts and cholesterol, and secondarily increases cholesterol turnover in the liver: A. Gemfibrozil B. Cholestyramine C. Lovastatin D. Bezafibrate
Last Answer : B. Cholestyramine
Description : The most important channel of elimination of digoxin is: A. Glomerular filtration B. Tubular secretion C. Hepatic metabolism D. Excretion in bile
Last Answer : A. Glomerular filtration
Description : Tests of coagulation are used to monitor anticoagulation treatment and detect intrinsic abnormalities in coagulation. Which of the following statement(s) is/are true concerning ... is used to monitor heparin levels intraoperatively during cardiovascular and peripheral vascular operations
Last Answer : Answer: a, c, d Coagulation tests include prothrombin time (PT), which measures the intrinsic and extrinsic pathways of fibrinogen production and is the most common method for ... more while for peripheral vascular applications, values of 250 seconds or greater are considered appropriate
Description : Antithrombin III deficiency is a commonly observed hypercoaguable state. Which of the following statement(s) is/are true concerning this condition? a. A patient with this deficiency usually ... involves acutely the administration of fresh frozen plasma followed by long-term treatment with Coumadin
Last Answer : Answer: a, b, c, d Antithrombin III deficiency accounts for about 2% of venous thrombotic event. This deficiency has been described in patients with pulmonary embolism, mesenteric venous ... is established, fresh frozen plasma should be administered followed by long-term treatment with Coumadin
Description : Blood does not coagulate inside the body due to the presence of (a) haemoglobin (b) heparin (c) fibrin (d) plasma
Last Answer : Ans:(b)
Description : Blood does not coagulate inside the body due to the presence of – (1) Plasma (2) Haemoglobin (3) Heparin (4) Fibrin
Last Answer : (3) Heparin Explanation: Heparin is a naturally-occurring anticoagulant produced by basophils and mast cells. Heparin acts as an anticoagulant, preventing the formation of clots and extension of existing clots ... is present in the walls of blood vessels where it doesn't allow blood to clot.
Description : You are required to draw blood from a patient and to keep it in a test tube for analysis of blood corpuscles and plasma. You are also provided with the following four types of test tubes ... bicarbonate (b) Chilled test tube (c) Test tube containing heparin (d) Test tube containing sodium oxalate
Last Answer : (a) Test tube containing calcium bicarbonate
Description : hematological disease occurs in children treated with heparin and fresh frozen plasma what is the disease : A)hemophilia A B)hemophilia B C )VON WILL brand disease d)DIC thrombosis
Last Answer : d)DIC thrombosis
Description : The function of lymphocytes is/are________ a. Production of heparin b. Production of antibodies c. Production of plasma d. Production of haemoglobin protein
Last Answer : b. Production of antibodies
Description : Blood does not coagulate inside the body due to the presence of (1) Plasma (2) Haemoglobin (3) Heparin (4) Fibrin
Last Answer : Heparin
Description : A patient of pulmonary tuberculosis treated with rifampin + isoniazid + pyrazinamide developed parasthesias, weakness, dizziness, ataxia and depressed tendon reflexes. Which of the following ... with thiacetazone C. Substitute pyrazinamide with ethambutol D. Substitute rifampin with streptomycin
Last Answer : A. Temporarily discontinue isoniazid and add pyridoxine
Description : A patient of liver cirrhosis with ascitis was treated with hydrochlorothiazide 50 mg twice daily. He responded initially, but over a couple of months the diuretic action gradually diminished ... Add spironolactone 50 mg thrice daily D. Substitute hydrochlorothiazide by spironolactone 50 mg 6 hourly
Last Answer : C. Add spironolactone 50 mg thrice daily
Description : Which of the following statements most closely describes the current status of angiotensin converting enzyme inhibitors in congestive heart failure: A. They are the first choice drugs unless contraindicated B. ... substitute for digitalis D. They are to be used as adjuncts only in resistant cases
Last Answer : D. They are to be used as adjuncts only in resistant cases
Description : An epileptic woman controlled by phenytoin therapy conceives. Which of the following measures is most appropriate: A. Medical termination of pregnancy B. Withdraw phenytoin therapy C. ... lowest effective level D. Substitute phenytoin with a combination of carbamazepine and sodium valproate
Last Answer : C. Gradually reduce phenytoin dose to the lowest effective level
Description : A patient of chronic bronchial asthma maintained on oral prednisolone 20 mg daily and inhaled salbutamol as required develops chest infection. Which of the following measures is recommended: A. ... mg/day C. No change/increase in prednisolone dose D. Substitute prednisolone with inhaled budesonid
Last Answer : C. No change/increase in prednisolone dose
Description : Choose the correct statement about drotaverine: A. It is a smooth muscle antispasmodic acting by non-anticholinergic mechanisms B. It is a papaverine congener used in peripheral vascular diseases C. It ... used to control diarrhoea D. It is a M1/M3 selective antagonist used for spastic constipation
Last Answer : A. It is a smooth muscle antispasmodic acting by non-anticholinergic mechanisms
Description : What is true of nicotinic acid as well as nicotinamide: A. Both possess vitamin B3 activity B. Both cause cutaneous vasodilatation C. Both lower plasma triglyceride and VLDL levels D. Both cause hyperglycaemia after prolonged medication
Last Answer : A. Both possess vitamin B3 activity
Description : Iron sorbitol-citric acid differs from iron dextran in that: A. It cannot be injected i.v. B. It is not excreted in urine C. It is not bound to transferrin in plasma D. It produces fewer side effects
Last Answer : A. It cannot be injected i.v
Description : Actions of thyroxine include the following except: A. Induction of negative nitrogen balance B. Reduction in plasma cholesterol level C. Fall in plasma free fatty acid level D. Rise in blood sugar leve
Last Answer : C. Fall in plasma free fatty acid level
Description : 17.5 Actions of thyroxine include the following except: A. Induction of negative nitrogen balance B. Reduction in plasma cholesterol level C. Fall in plasma free fatty acid level D. Rise in blood sugar level
Last Answer : D. Rise in blood sugar level
Description : Weakly acidic drugs: A. Are bound primarily to α1 acid glycoprotein in plasma B. Are excreted faster in alkaline urine C. Are highly ionized in the gastric juice D. Do not cross blood-brain barrier
Last Answer : B. Are excreted faster in alkaline urine
Description : Allopurinol lowers the plasma concentration of: A. Hypoxanthine B. Xanthine C. Uric acid D. All of the above
Last Answer : C. Uric acid
Description : The plasma half life of aspirin (along with salicylic acid released from it): A. Remains constant irrespective of dose B. Is longer for antiinflammatory doses compared to that for analgesic ... for antiinflammatory doses compared to that for analgesic dose D. Can be shortened by acidifying urine
Last Answer : B. Is longer for antiinflammatory doses compared to that for analgesic dose
Description : What's a good free text expander?
Last Answer : Is this what you’re looking for? http://lifehacker.com/5844126/the-best-text-expansion-app-for-windows
Description : Should me computer, router and router range expander all have the same IP Address?
Last Answer : They may not have the same IP address. IP addresses must be unique.
Description : What is the best text expander program for a mac?
Last Answer : I use good'ole TextExpander, and it's my favorite - of the few I've tried. The others weren't even good enough to remember the names of. I recently noticed under the Language & Text setting ... a free alternative to third-party text-expander programs out there (if you can get it working that is).
Description : ECE Board Exam March 1996 The expander in a companding device provides ___________. A. greater amplification for low signal levels B. less amplification for low signal levels C. greater amplification for high signal levels D. lesser pressure for transmission
Last Answer : B. less amplification for low signal levels
Description : In Wilson’s disease (A) Copper fails to be excreted in the bile (B) Copper level in plasma is decreased (C) Ceruloplasmin level is increased (D) Intestinal absorption of copper is decreased
Last Answer : Answer : A
Description : Roxithromycin has the following advantage(s) over erythromycin: A. It is more effective in whooping cough B. It causes less gastric irritation C. It has longer plasma half-life D. Both 'B' and 'C' are correct
Last Answer : D. Both 'B' and 'C' are correct
Description : Ceftriaxone has all the following attributes except: A. It has a long plasma half life of 8 hours B. It can cause bleeding by prolonging prothrombin time C. It has attained high cure rates in multiresistant typhoid infection D. It penetrates CSF poorly and therefore not effective in meningitis
Last Answer : D. It penetrates CSF poorly and therefore not effective in meningitis
Description : Trimethoprim is combined with sulfamethoxazole in a ratio of 1:5 to yield a steady state plasma concentration ratio of: A. Trimethoprim 1: Sulfamethoxazole 5 B. Trimethoprim 1: Sulfamethoxazole 10 C. Trimethoprim 1: Sulfamethoxazole 20 D. Trimethoprim 5: Sulfamethoxazole 1
Last Answer : C. Trimethoprim 1: Sulfamethoxazole 20
Description : Plasma expanders are used in the following conditions except: A. Congestive heart failure B. Extensive burns C. Mutilating injuries D. Endotoxin shock
Last Answer : A. Congestive heart failure