Hyperuricaemia is produced by the following drugs except: A. Ethambutol B. Pyrazinamide C. Sulfinpyrazone D. Hydrochlorothiazide

1 Answer

Answer :

C. Sulfinpyrazone

Related questions

Description : First line antitubercular drugs include the following except: A. Ciprofloxacin B. Streptomycin C. Pyrazinamide D. Ethambutol

Last Answer : A. Ciprofloxacin

Description : Which of the following antitubercular drugs is not hepatotoxic: A. Isoniazid B. Rifampicin C. Pyrazinamide D. Ethambutol

Last Answer : D. Ethambutol

Description : According to the current WHO guidelines, new (untreated) sputum smear positive cases of pulmonary tuberculosis are to be treated with the following regimen: A. Isoniazid + Rifampin + Pyrazinamide ... D. Isoniazid + Rifampin for 6 months with additional Pyrazinamide during the initial 2 months

Last Answer : C. Isoniazid + Rifampin for 6 months with additional Pyrazinamide + Ethambutol/Streptomycin during the initial 2 months

Description : Addition of pyrazinamide and ethambutol for the first two months to the isoniazid + rifampin therapy of tuberculosis serves the following purpose(s): A. Reduces the total duration of therapy to 6 months B. ... sputum conversion C. Permits reduction of rifampin dose D. Both A' and B' are correct

Last Answer : D. Both ‘A’ and ‘B’ are correc

Description : In the short course regimen for treatment of tuberculosis, pyrazinamide and ethambutol are used for: A. Initial one month B. Initial two months C. Last two months D. Throughout the course

Last Answer : B. Initial two months

Description : Indicate the second line antitubercular drug that is being preferred to supplement ethambutol + streptomycin in case of hepatotoxicity due to isoniazid/ rifampin/pyrazinamide: A. Ethionamide B. Cycloserine C. Ofloxacin D. Capreomycin

Last Answer : C. Ofloxacin

Description : Which first line antitubercular drug is only tuberculostatic and not tuberculocidal: A. Rifampin B. Isoniazid C. Ethambutol D. Pyrazinamide

Last Answer : C. Ethambutol

Description : The intermittently multiplying (spurter) tubercle bacilli present within caseous material having low oxygen tension are most susceptible to: A. Ethambutol B. Rifampin C. Streptomycin D. Pyrazinamide

Last Answer : B. Rifampin

Description : A patient of pulmonary tuberculosis treated with rifampin + isoniazid + pyrazinamide developed parasthesias, weakness, dizziness, ataxia and depressed tendon reflexes. Which of the following ... with thiacetazone C. Substitute pyrazinamide with ethambutol D. Substitute rifampin with streptomycin

Last Answer : A. Temporarily discontinue isoniazid and add pyridoxine

Description : Allopurinol has a therapeutic effect in the following conditions except: A. Radiotherapy induced hyperuricaemia B. Hydrochlorothiazide induced hyperuricaemia C. Acute gouty arthritis D. Kala-azar

Last Answer : C. Acute gouty arthritis

Description : The drugs used to treat Mycobact. avium complex infection in AIDS patients include the following except: A. Isoniazid B. Clarithromycin C. Ethambutol D. Ciprofloxacin

Last Answer : A. Isoniazid

Description : Spironolactone can be usefully combined with the following diuretics except: A. Furosemide B. Amiloride C. Hydrochlorothiazide D. Chlorthalidone

Last Answer : B. Amiloride

Description : The principles of antihypertensive drug usage enunciated in JNC VI and WHO-ISH guidelines include the following except: A. Therapy for grade I and II hypertension should be initiated with a single drug ... initially fails to lower BP, it should be replaced by a drug/combination from another class

Last Answer : C. All subjects with BP higher than 140/90 mmHg should be put on antihypertensive medication immediately

Description : The following drug increases cyclic-AMP in platelets and inhibits their aggregation without altering levels of thromboxane A2 or prostacyclin: A. Aspirin B. Sulfinpyrazone C. Dipyridamole D. Abciximab

Last Answer : C. Dipyridamole

Description : Sulfinpyrazone has the following action(s): A. Antiplatelet aggregatory B. Uricosuric C. Antiinflammatory D. Both ‘A’ and ‘B’

Last Answer : D. Both ‘A’ and ‘B’

Description : n addition to counteracting potassium loss, triamterene also opposes the following consequence of thiazide/furosemide therapy: A. Hyperuricaemia B. Rise in plasma LDL-cholesterol C. Magnesium loss D. Both ‘A’ and ‘C’ are correct

Last Answer : C. Magnesium loss

Description : Furosemide is to be preferred over hydrochlorothiazide when hypertension is accompanied by: A. Asthma B. Hyperuricaemia C. Diabetes D. Congestive heart failure

Last Answer : D. Congestive heart failure

Description : The ‘neuroleptic syndrome’ produced by chlorpromazine like drugs is characterized by the following except: A. Emotional quietening B. Paucity of movements C. Ataxia D. Indifference to external cues

Last Answer : C. Ataxia

Description : ifampin + pyrazinamide for initial 2 months followed by isoniazid + rifampin for another 4 months for the following category of tubercular patients: A. New sputum positive cases of ... pulmonary tuberculosis who have interrupted treatment for more than 2 months D. Tubercular meningitis patients

Last Answer : B. New sputum negative cases of pulmonary tuberculosis

Description : In a patient of pulmonary tuberculosis, pyrazinamide is most active on the following subpopulation of tubercle bacilli: A. Rapidly multiplying bacilli located on cavity walls B. Slow ... showing inflammatory response C. Intermittently multiplying bacilli within caseous material D. Dormant bacilli

Last Answer : B. Slow growing bacilli within macrophages and at sites showing inflammatory response

Description : Which of the following drugs may be effective in the treatment of gouty arthritis by acting by two separate and distinct mechanisms? (a) Allopurinol (b) Probenecid (c) Colchicine (d) Indomethacin (e) Sulfinpyrazone

Last Answer : Ans: D

Description : Under the WHO guidelines for treatment of new cases of tuberculosis, when isoniazid + ethambutol are used in the continuation phase instead of isoniazid + rifampin,, the duration of this phase is: A. 2 months B. 4 months C. 6 months D. 8 month

Last Answer : C. 6 months

Description : The characteristic toxicity of ethambutol is: A. Hepatitis B. Visual defects C. Vestibular disturbance D. Renal damage

Last Answer : B. Visual defects

Description : Ethambutol is not used in children below 6 years of age because: A. Young children are intolerant to ethambutol B. Ethambutol causes growth retardation in young children C. It is ... induced visual impairment in young children D. In young children visual toxicity of ethambutol is irreversible

Last Answer : C. It is difficult to detect ethambutol induced visual impairment in young children

Description : Which antimicrobial should be avoided in patients of liver disease: A. Tetracycline B. Cotrimoxazole C. Cephalexin D. Ethambutol

Last Answer : A. Tetracycline

Description : Which of the following is associated with Hyperuricaemia? 1) is usually due to an excess purine consumption 2) occurs in association with acute lymphoblastic leukaemia 3) in primary gout is inherited in ... with low dose aspirin therapy 5) can be treated with uricosuric drugs even in renal failure

Last Answer : Answers-2 Hyperuricaemia may be due to increased purine intake, urate production or reduced urate clearance, and is most commonly due to the latter. Therefore it can occur in association with enhanced ... . Many of the uricosuric drugs may be detrimental in renal failure and may not be effective.

Description : The following drug reduces urine volume in both pituitary origin as well as renal diabetes insipidus and is orally active: A. Vasopressin B. Hydrochlorothiazide C. Chlorpropamide D. Carbamazepine

Last Answer : B. Hydrochlorothiazide

Description : Use of potassium sparing diuretics in patients receiving the following drug needs close monitoring: A. Furosemide B. Hydrochlorothiazide C. Captopril D. Verapami

Last Answer : C. Captopril

Description : A patient of liver cirrhosis with ascitis was treated with hydrochlorothiazide 50 mg twice daily. He responded initially, but over a couple of months the diuretic action gradually diminished ... Add spironolactone 50 mg thrice daily D. Substitute hydrochlorothiazide by spironolactone 50 mg 6 hourly

Last Answer : C. Add spironolactone 50 mg thrice daily

Description : At equinatriuretic doses which diuretic causes the maximum K+ loss: A. Furosemide B. Hydrochlorothiazide C. Acetazolamide D. Amiloride

Last Answer : C. Acetazolamide

Description : The following diuretic abolishes the corticomedullary osmotic gradient in the kidney: A. Acetazolamide B. Furosemide C. Hydrochlorothiazide D. Spironolactone

Last Answer : B. Furosemide

Description : The following antihypertensive combination is irrational, and therefore should not be used: A. Nifedipine + hydralazine B. Amlodipine + atenolol C. Enalapril + clonidine D. Enalapril + hydrochlorothiazide

Last Answer : TA. Nifedipine + hydralazine

Description : Rebound hypertension on sudden stoppage of medication is most likely to occur with: A. Hydrochlorothiazide B. Prazosin C. Clonidine D. Lisinopri

Last Answer : C. Clonidine

Description : The following antihypertensive drug has a favourable effect on plasma lipid profile: A. Prazosin B. Propranolol C. Hydrochlorothiazide D. Furosemide

Last Answer : A. Prazosin

Description : A 40-year-old politician suffered from attacks of chest pain diagnosed as angina pectoris. He had a tense personality, resting heart rate was 96/min, blood pressure 170/104 mm Hg, but ... antihypertensive for initial therapy in his case: A. Nifedipine B. Hydrochlorothiazide C. Atenolol D. Methyldopa

Last Answer : C. Atenolol

Description : Select the drug which can markedly potentiate the vasodilator action of organic nitrates: A. Propranolol B. Fluoxetine C. Hydrochlorothiazide D. Sildenafil

Last Answer : D. Sildenafil

Description : The preferred diuretic for mobilizing edema fluid in CHF is: A. Hydrochlorothiazide B. Furosemide C. Metolazone D. Amiloride

Last Answer : B. Furosemide

Description : Renal excretion of lithium is reduced by: A. Furosemide B. Hydrochlorothiazide C. Indomethacin D. All of the above

Last Answer : D. All of the above

Description : The hypoglycaemic action of sulfonylureas is likely to be attenuated by the concurrent use of: A. Hydrochlorothiazide B. Propranolol C. Theophylline D. Aspirin

Last Answer : A. Hydrochlorothiazide

Description : Because of proven beneficial effects on “cardiac remodeling”, these agents are now indicated as first line therapy in CHF patients. Which of the following is representative of this group of drugs? (a) Hydrochlorothiazide (b) Enalapril (c) Furosemide (d) Carvedilol (e) Bumetanide

Last Answer : Ans: B

Description : Compared to the drug named within parenthesis, which of the following drugs has a higher potency but lower efficacy: A. Pethidine (morphine) B. Furosemide (hydrochlorothiazide) C. Diazepam (pentobarbitone) D. Enalapril (captopril)

Last Answer : C. Diazepam (pentobarbitone)

Description : Compared to the drug named within parenthesis, which of the following drugs has a higher potency but lower efficacy: A. Pethidine (morphine) B. Furosemide (hydrochlorothiazide) C. Diazepam (pentobarbitone) D. Enalapril (captopril)

Last Answer : C. Diazepam (pentobarbitone)

Description : Practically all antineoplastic drugs can produce the following toxic effects except: A. Depression of leucocyte count B. Mucositis C. Cardiomyopathy D. Oligozoospermia

Last Answer : C. Cardiomyopathy

Description : Chloroquine resistant P. falciparum malaria can be cured by the following drugs except: A. Quinine B. Pyrimethamine + sulfadoxine C. Primaquine D. Artesunate

Last Answer : C. Primaquine

Description : The following are topical antifungal drugs except: A. Ciclopirox olamine B. Tolnaftate C. Crotamiton D. Terbinafine

Last Answer : C. Crotamiton

Description : The following drugs are effective in systemic mycosis except: A. Terbinafine B. Itraconazole C. Ketoconazole D. Fluconazol

Last Answer : A. Terbinafine

Description : Bacteriostatic drugs are unlikely to effect cure of bacterial infection in the following category of patients except: A. Diabetic patients B. Patients with allergic disorders C. Patients on corticosteroid therapy D. Subacute bacterial endocarditis patient

Last Answer : B. Patients with allergic disorders

Description : The following is true of proton pump inhibitors except: A. They are the most effective drugs for Zolinger Ellison syndrome B. Their prolonged use can cause atrophy of gastric mucosa C. They inhibit growth of H. pylori in stomach D. They have no effect on gastric motilit

Last Answer : B. Their prolonged use can cause atrophy of gastric mucosa

Description : Indications for the use of antiplatelet drugs include the following except: A. Secondary prophylaxis of myocardial infarction B. Unstable angina pectoris C. Disseminated intravascular coagulation D. Stroke prevention in patients with transient ischaemic attacks

Last Answer : C. Disseminated intravascular coagulation