At equinatriuretic doses which diuretic causes the
maximum K+
 loss:
A. Furosemide
B. Hydrochlorothiazide
C. Acetazolamide
D. Amiloride

1 Answer

Answer :

C. Acetazolamide

Related questions

Description : A 55-year-old patient with severe posthepatitis cirrhosis is started on a diuretic for another condition. Two days later he is found in a coma. The drug most likely to cause coma in a patient with cirrhosis is (a) Acetazolamide (b) Amiloride (c) Furosemide (d) Hydrochlorothiazide (e) Spironolactone

Last Answer : Ans: A

Description : The following diuretic abolishes the corticomedullary osmotic gradient in the kidney: A. Acetazolamide B. Furosemide C. Hydrochlorothiazide D. Spironolactone

Last Answer : B. Furosemide

Description : The preferred diuretic for mobilizing edema fluid in CHF is: A. Hydrochlorothiazide B. Furosemide C. Metolazone D. Amiloride

Last Answer : B. Furosemide

Description : Select the diuretic that can cause gynaecomastia, hirsutism and menstrual disturbance as a side effect on long-term use: A. Amiloride B. Spironolactone C. Metolazone D. Acetazolamide

Last Answer : B. Spironolactone

Description : Spironolactone can be usefully combined with the following diuretics except: A. Furosemide B. Amiloride C. Hydrochlorothiazide D. Chlorthalidone

Last Answer : B. Amiloride

Description : A patient of liver cirrhosis with ascitis was treated with hydrochlorothiazide 50 mg twice daily. He responded initially, but over a couple of months the diuretic action gradually diminished ... Add spironolactone 50 mg thrice daily D. Substitute hydrochlorothiazide by spironolactone 50 mg 6 hourly

Last Answer : C. Add spironolactone 50 mg thrice daily

Description : The most appropriate measure to overcome diminished responsiveness to furosemide after its longterm use is: A. Switching over to parenteral administration of furosemide B. Addition of a thiazide diuretic C. Addition of acetazolamide D. Potassium supplementation

Last Answer : B. Addition of a thiazide diuretic

Description : Which of the following diuretics would be most useful in a patient with cerebral edema? (a) Acetazolamide (b) Amiloride (c) Ethacrynic acid (d) Furosemide (e) Mannitol

Last Answer : Ans: E

Description : Which of the following therapies would be most useful in the management of severe hypercalcemia? (a) Amiloride plus saline infusion (b) Furosemide plus saline infusion (c) Hydrochlorothiazide plus saline infusion (d) Mannitol plus saline infusion (e) Spironolactone plus saline infusion

Last Answer : Ans: B

Description : Select the diuretic that is most effective in acute congestive glaucoma: A. Indapamide B. Amiloride C. Mannitol D. Furosemide

Last Answer : C. Mannitol

Description : Select the diuretic that is most effective in acute congestive glaucoma: A. Indapamide B. Amiloride C. Mannitol D. Furosemide

Last Answer : C. Mannitol

Description : Select the diuretic which is orally active, efficacious in acidosis as well as alkalosis, causes diuresis even in renal failure and has additional carbonic anhydrase inhibitory action: A. Mannitol B. Benzthiazide C. Indapamide D. Furosemide

Last Answer : D. Furosemide

Description : The following is not itself an efficacious diuretic, and is used only as an adjuvant/corrective to other diuretics: A. Acetazolamide B. Metolazone C. Spironolactone D. Indapamide

Last Answer : C. Spironolactone

Description : Which of the following has a ‘self limiting diuretic’ (action of the drug itself causing changes which limit further diuresis) action: A. Indapamide B. Spironolactone C. Xipamide D. Acetazolamide

Last Answer : D. Acetazolamide

Description : Use of potassium sparing diuretics in patients receiving the following drug needs close monitoring: A. Furosemide B. Hydrochlorothiazide C. Captopril D. Verapami

Last Answer : C. Captopril

Description : The following antihypertensive drug has a favourable effect on plasma lipid profile: A. Prazosin B. Propranolol C. Hydrochlorothiazide D. Furosemide

Last Answer : A. Prazosin

Description : Renal excretion of lithium is reduced by: A. Furosemide B. Hydrochlorothiazide C. Indomethacin D. All of the above

Last Answer : D. All of the above

Description : The principles of antihypertensive drug usage enunciated in JNC VI and WHO-ISH guidelines include the following except: A. Therapy for grade I and II hypertension should be initiated with a single drug ... initially fails to lower BP, it should be replaced by a drug/combination from another class

Last Answer : C. All subjects with BP higher than 140/90 mmHg should be put on antihypertensive medication immediately

Description : Nonsteroidal antiinflammatory drugs reduce the diuretic action of furosemide by: A. Preventing prostaglandin mediated intrarenal haemodynamic actions B. Blocking the action in ascending limb of loop ... C. Enhancing salt and water reabsorption in distal tubule D. Increasing aldosterone secretion

Last Answer : A. Preventing prostaglandin mediated intrarenal haemodynamic actions

Description : The following diuretic reduces positive free water clearance but does not affect negative free water clearance: A. Hydroflumethiazide B. Furosemide C. Ethacrynic acid D. Mannitol

Last Answer : A. Hydroflumethiazide

Description : Select the diuretic which is similar in efficacy and pattern of electrolyte excretion to furosemide, but is 40 times more potent dose to dose: A. Piretanide B. Bumetanide C. Xipamide D. Metolazone

Last Answer : B. Bumetanide

Description : Parenteral furosemide is an alternative diuretic to mannitol in the following condition: A. Pulmonary edema B. Cirrhotic edema C. Cerebral edema D. Cardiac edema

Last Answer : C. Cerebral edema

Description : A patient of CHF was treated with furosemide and digoxin. He became symptom-free and is stable for the last 3 months with resting heart rate 68/min in sinus rhythm but left ventricular ... medication as before C. Continue the diuretic but stop digoxin D. Continue digoxin but stop the diuretic

Last Answer : A. Stop above medication and start an ACE inhibitor

Description : Of the following diuretic medications, which conserves potassium? a) Spironolactone (Aldactone) Aldactone is known as a potassium-sparing diuretic. b) Furosemide (Lasix) Lasix causes loss of ... (Diuril) Diuril causes mild hypokalemia. d) Chlorthalidone (Hygroton) Hygroton causes mild hypokalemia.

Last Answer : a) Spironolactone (Aldactone) Aldactone is known as a potassium-sparing diuretic.

Description : A drug that is useful in glaucoma and high-altitude sickness is (a) Acetazolamide (b) Amiloride (c) Demeclocycline (d) Desmopressin (e) Ethacrynic acid

Last Answer : Ans: A

Description : Amiloride has the following effect on urinary cation excretion: A. Decreases both K+ and H+ ion excretion B. Decreases K+ excretion but increases H+ ion excretion C. Increases K+ but decreases Na+ excretion D. Decreases both Na+ and K+ excretion

Last Answer : A. Decreases both K+ and H+ ion excretion

Description : Amiloride inhibits K+ excretion in the distal tubules and collecting ducts by blocking: A. Electrogenic K+ channels B. Electrogenic Na+ channels C. Nonelectrogenic Na+-Cl– symport D. H+K+ATPase

Last Answer : B. Electrogenic Na+ channels

Description : Aldosterone increases Na+ reabsorption and K+ excretion in the renal collecting duct cells by: A. Inducing synthesis of Na+K+ATPase B. Inducing synthesis of amiloride sensitive Na+ channels C. Translocating Na+ channels from cytosolic site to luminal membrane D. All of the above

Last Answer : D. All of the above

Description : All the following diuretics inhibit the carbonic anhydrase except (A) Acetazolamide (B) Bumetanide (C) Furosemide (D) Ethacrynic acid

Last Answer : Answer : D

Description : Choose the correct statement about amiloride: A. It antagonises the action of aldosterone B. It can be used to treat lithium induced diabetes insipidus C. It increases calcium loss in urine D. It is dose to dose less potent than triamterene

Last Answer : B. It can be used to treat lithium induced diabetes insipidus

Description : A diuretic which is an aldosterone antagonist is (A) Spironolactone (B) Ethacrynic acid (C) Acetazolamide (D) Chlorothiazide

Last Answer : Answer : A

Description : Because of proven beneficial effects on “cardiac remodeling”, these agents are now indicated as first line therapy in CHF patients. Which of the following is representative of this group of drugs? (a) Hydrochlorothiazide (b) Enalapril (c) Furosemide (d) Carvedilol (e) Bumetanide

Last Answer : Ans: B

Description : Compared to the drug named within parenthesis, which of the following drugs has a higher potency but lower efficacy: A. Pethidine (morphine) B. Furosemide (hydrochlorothiazide) C. Diazepam (pentobarbitone) D. Enalapril (captopril)

Last Answer : C. Diazepam (pentobarbitone)

Description : Compared to the drug named within parenthesis, which of the following drugs has a higher potency but lower efficacy: A. Pethidine (morphine) B. Furosemide (hydrochlorothiazide) C. Diazepam (pentobarbitone) D. Enalapril (captopril)

Last Answer : C. Diazepam (pentobarbitone)

Description : Following potassium sparing diuretic is a mineralocorticoid receptor antagonist (a) Amiloride (b) Triamterene (c) Spironolactone (d) All of the above

Last Answer : Ans: C

Description : Following potassium sparing diuretic inhibits action of aldosterone (a) Amiloride (b) Triamterene (c) Spironolactone (d) All of the above

Last Answer : Ans: C

Description : Furosemide acts by inhibiting the following in the renal tubular cell: A. Na+-K+-2Cl– cotransporter B. Na+-Cl– symporter C. Na+-H+ antiporter D. Na+ K+ ATPase

Last Answer : A. Na+-K+-2Cl– cotransporter

Description : The following diuretic acts on the luminal membrane of distal tubule and collecting ducts to inhibit electrogenic Na+ reabsorption so that K+ excretion is diminished and bicarbonate excretion is enhanced: A. Xipamide B. Isosorbide C. Triamterene D. Spironolactone

Last Answer : C. Triamterene

Description : n addition to counteracting potassium loss, triamterene also opposes the following consequence of thiazide/furosemide therapy: A. Hyperuricaemia B. Rise in plasma LDL-cholesterol C. Magnesium loss D. Both ‘A’ and ‘C’ are correct

Last Answer : C. Magnesium loss

Description : Select the antihistaminic which blocks cardiac K+ channels when given in high doses or along with drugs that inhibit CYP3A4 isoenzyme: A. Chlorpheniramine B. Promethazine C. Astemizole D. Loratadine

Last Answer : C. Astemizole

Description : Following loop diuretic is a phynoxy acetic acid derivative (a) Furosemide (b) Bumetanide (c) Ethacrynic acid (d) All of the above

Last Answer : Ans: C

Description : Which of the following medications is categorized as a loop diuretic? a) Furosemide (Lasix) Lasix is commonly used in the treatment of cardiac failure. b) Chlorothiazide (Diuril) ... thiazide diuretic. d) Spironolactone (Aldactone) Spironolactone is categorized as a potassium-sparing diuretic.

Last Answer : a) Furosemide (Lasix) Lasix is commonly used in the treatment of cardiac failure.

Description : Though ethacrynic acid is also a high ceiling diuretic, it is practically not used because: A. It is more ototoxic B. It causes diarrhoea and gut bleeding C. Its response increases steeply over a narrow dose range D. All of the above

Last Answer : D. All of the above

Description : In patients of hepatic cirrhosis: A. The extent of change in pharmacokinetics of drugs can be predicted from the values of liver function tests B. High doses of furosemide can be safely used C. Metformin is the preferred oral hypoglycaemic D. Disposition of atenolol is not significantly affected

Last Answer : D. Disposition of atenolol is not significantly affected

Description : In patients of hepatic cirrhosis: A. The extent of change in pharmacokinetics of drugs can be predicted from the values of liver function tests B. High doses of furosemide can be safely used C. Metformin is the preferred oral hypoglycaemic D. Disposition of atenolol is not significantly affected

Last Answer : D. Disposition of atenolol is not significantly affected

Description :  Which of the following is seen at low (analgesic) doses of aspirin: A. Respiratory stimulation B. Increased occult blood loss in stools C. Increased cardiac output D. Hyperglycaemia

Last Answer : B. Increased occult blood loss in stools

Description : he current therapeutic indication of acetazolamide is: A. Congestive heart failure B. Renal insufficiency C. Cirrhosis of liver D. Glaucoma

Last Answer : D. Glaucoma

Description : The following is a competitive type of enzyme inhibitor: A. Acetazolamide B. Disulfiram C. Physostigmine D. Theophylline

Last Answer : C. Physostigmine