Cross resistance among different members of the following class of antimicrobials is absent / incomplete or unidirectional: A. Aminoglycosides B. Macrolides C. Tetracyclines D. Both ‘B’ and ‘C’ are correct

Cross resistance among different members of the
following class of antimicrobials is absent / incomplete or unidirectional:
A. Aminoglycosides
B. Macrolides
C. Tetracyclines
D. Both ‘B’ and ‘C’ are correct
by

1 Answer

Answer :

A. Aminoglycosides
by

Related questions

Select the class of antibiotics which act by interfering with bacterial protein synthesis, but are bactericidal: A. Tetracyclines B. Aminoglycosides C. Macrolides D. Lincosamides

Description : Select the class of antibiotics which act by interfering with bacterial protein synthesis, but are bactericidal: A. Tetracyclines B. Aminoglycosides C. Macrolides D. Lincosamides

Last Answer : B. Aminoglycosides

Antibacterial agents can be classified with regard to their structure, mechanism of action, and activity pattern against various types of bacterial pathogens. Which of the following statement(s) is/are true concerning antimicrobial classes? a. Penicillins and cephalosporins share the compound structure of a b-lactam ring which binds to bacterial division plate proteins b. Tetracyclines and macrolides such as erythromycin inhibit bacterial ribosomal activity and therefore protein synthesis c. Aminoglycosides act in a similar fashion to tetracyclines and therefore are both bacteriostatic d. Sulfonamides and trimethoprim act synergistically to inhibit purine synthesis

Description : Antibacterial agents can be classified with regard to their structure, mechanism of action, and activity pattern against various types of bacterial pathogens. Which of the following ... are both bacteriostatic d. Sulfonamides and trimethoprim act synergistically to inhibit purine synthesis

Last Answer : Answer: a, b, d Penicillins, cephalosporins, and monobactams possess a b-lactam ring of some type and act to bind bacterial division plate proteins, thus inhibiting cell wall ... act in different mechanisms to inhibit protein synthesis, therefore two agents in combination act synergistically

Antibiotics inhibiting nucleic acid synthesis include a. Rifampin and quinolones. b. Aminoglycosides and tetracyclines. c. Lincosamides and streptogramins.d. Macrolides and ami noglycosides..

Description : Antibiotics inhibiting nucleic acid synthesis include a. Rifampin and quinolones. b. Aminoglycosides and tetracyclines. c. Lincosamides and streptogramins. d. Macrolides and ami noglycosides.

Last Answer : a. Rifampin and quinolones.

Drug destroying type of bacterial resistance is important for the following antibiotics except: A. Cephalosporins B. Tetracyclines C. Chloramphenicol D. Aminoglycosides

Description : Drug destroying type of bacterial resistance is important for the following antibiotics except: A. Cephalosporins B. Tetracyclines C. Chloramphenicol D. Aminoglycosides

Last Answer : B. Tetracyclines

Stevens Johnson sjmdrome is the most common adverse effect associated with one of the following category of drugs : (A) Sulphonamides (B) Macrolides (C) Penicillins (D) Tetracyclines

Description : Stevens Johnson sjmdrome is the most common adverse effect associated with one of the following category of drugs : (A) Sulphonamides (B) Macrolides (C) Penicillins (D) Tetracyclines

Last Answer : (A) Sulphonamides

Mammalian cells are not inhibited by low concentrations of tetracyclines that inhibit sensitive microorganisms because: A. Host cells lack active transport mechanism for tetracyclines B. Host cells actively pump out tetracyclines C. Protein synthesizing apparatus of host cells has low affinity for tetracyclines D. Both ‘A’ and ‘C’ are correct

Description : Mammalian cells are not inhibited by low concentrations of tetracyclines that inhibit sensitive microorganisms because: A. Host cells lack active transport mechanism for tetracyclines B. Host cells actively pump out ... host cells has low affinity for tetracyclines D. Both A' and C' are correct

Last Answer : D. Both ‘A’ and ‘C’ are correct

Antimicrobials effective against anaerobic bacteria include the following except: A. Tobramycin B. Clindamicin C. Chloramphenicol D. Metronidazole

Description : Antimicrobials effective against anaerobic bacteria include the following except: A. Tobramycin B. Clindamicin C. Chloramphenicol D. Metronidazole

Last Answer : A. Tobramycin

Combination therapy with two (or more) antimicrobials is superior to monotherapy with any single effective drug in case of the following diseases except: A. Typhoid fever B. Leprosy C. AIDS D. Subacute bacterial endocarditis

Description : Combination therapy with two (or more) antimicrobials is superior to monotherapy with any single effective drug in case of the following diseases except: A. Typhoid fever B. Leprosy C. AIDS D. Subacute bacterial endocarditis

Last Answer : A. Typhoid fever

Choose the condition which is mostly treated with a combination of antimicrobials: A. Lobar pneumonia B. Typhoid C. Peritonitis D. Syphilis

Description : Choose the condition which is mostly treated with a combination of antimicrobials: A. Lobar pneumonia B. Typhoid C. Peritonitis D. Syphilis

Last Answer : C. Peritonitis

A patient of congestive heart failure was being treated with furosemide and digoxin. He developed urinary tract infection. Which of the following antimicrobials should be avoided: A. Ampicillin B. Gentamicin C. Norfloxacin D. Cotrimoxazole

Description : A patient of congestive heart failure was being treated with furosemide and digoxin. He developed urinary tract infection. Which of the following antimicrobials should be avoided: A. Ampicillin B. Gentamicin C. Norfloxacin D. Cotrimoxazole

Last Answer : B. Gentamicin

The following antibiotic(s) exert(s) a long postantibiotic effect: A. Fluoroquinolones B. β-lactams C. Aminoglycosides D. All of the above

Description : The following antibiotic(s) exert(s) a long postantibiotic effect: A. Fluoroquinolones B. β-lactams C. Aminoglycosides D. All of the above

Last Answer : D. All of the above

Choose the correct statement about tetracyclines: A. Being broad spectrum antibioics they are dependable for empirical treatment of lifethreatening infections B. Currently, they are not the first choice antibiotic for any specific infection C. They reduce stool volume and duration of diarrhoea in cholera D. The are preferred for treatment of anaerobic bacterial infections

Description : Choose the correct statement about tetracyclines: A. Being broad spectrum antibioics they are dependable for empirical treatment of lifethreatening infections B. Currently, they are not the first ... of diarrhoea in cholera D. The are preferred for treatment of anaerobic bacterial infections

Last Answer : C. They reduce stool volume and duration of diarrhoea in cholera

Chloramphenicol is more active than tetracyclines against: A. Bateroides fragilis B. Treponema pallidum C. Streptococci D. Staphylococci

Description : Chloramphenicol is more active than tetracyclines against: A. Bateroides fragilis B. Treponema pallidum C. Streptococci D. Staphylococci

Last Answer : a

Tetracyclines are active against the following gram negative bacteria: A. Salmonella typhi B. Pseudomonas aeruginosa C. Yersinia pestis D. All of the above

Description : Tetracyclines are active against the following gram negative bacteria: A. Salmonella typhi B. Pseudomonas aeruginosa C. Yersinia pestis D. All of the above

Last Answer : C. Yersinia pestis

Tetracyclines are still the first choice drugs for the following disease: A. Granuloma inguinale B. Chancroid C. Syphilis D. Gonorrhoea in patients allergic to penicillin

Description : ]Tetracyclines are still the first choice drugs for the following disease: A. Granuloma inguinale B. Chancroid C. Syphilis D. Gonorrhoea in patients allergic to penicillin

Last Answer : A. Granuloma inguinale

Compared to older tetracyclines, doxycycline produces a lower incidence of superinfection diarrhoea because: A. It is completely absorbed in the small intestines so that drug concentration in the colonic contents is low B. It is inactivated by the gut microflora C. It is not active against the microbes of the normal gut flora D. It is a potent tetracycline and inhibits

Description : Compared to older tetracyclines, doxycycline produces a lower incidence of superinfection diarrhoea because: A. It is completely absorbed in the small intestines so that drug concentration in the colonic contents ... the microbes of the normal gut flora D. It is a potent tetracycline and inhibits

Last Answer : A. It is completely absorbed in the small intestines so that drug concentration in the colonic contents is low

CHOOSE THE MOST APPROPRIATE RESPONSE 41.1 Absorption of oral iron preparations can be facilitated by coadministering: A. Antacids B. Tetracyclines C. Phosphates D. Ascorbic acid

Description : CHOOSE THE MOST APPROPRIATE RESPONSE 41.1 Absorption of oral iron preparations can be facilitated by coadministering: A. Antacids B. Tetracyclines C. Phosphates D. Ascorbic acid

Last Answer : D. Ascorbic acid

Interaction between the following pair of drugs can be avoided by making suitable adjustments: A. Levodopa and metoclopramide B. Furosemide and indomethacin C. Tetracyclines and ferrous sulfate D. Clonidine and chlorpromazine

Description : Interaction between the following pair of drugs can be avoided by making suitable adjustments: A. Levodopa and metoclopramide B. Furosemide and indomethacin C. Tetracyclines and ferrous sulfate D. Clonidine and chlorpromazine

Last Answer : C. Tetracyclines and ferrous sulfate

Defination of Antimicrobials

Description : Defination of Antimicrobials

Last Answer : Antimicrobials Disease in man and animal which may be caused by bacteria, virus and other micro-organisms microbes. Any organism that causes diseases is called a pathogen. Many body secretions either ... to infection of the body. Antibiotics are the class of drugs used as antimicrobials.  

Which one of the following is NOT an inhibitor of protein synthesis? a. Clindamycin b. Macrolides c. Rifampin d. Chioramphenicol

Description : Which one of the following is NOT an inhibitor of protein synthesis? a. Clindamycin b. Macrolides c. Rifampin d. Chioramphenicol

Last Answer : c. Rifampin

Trimethoprim and sulfamethoxazole are examples of synthesis. a. Sulfonamides; PABA b. Penicillins; Cell Wall c. Sulfonamides; Folic Acid d. Macrolides; Protein

Description : Trimethoprim and sulfamethoxazole are examples of synthesis. a. Sulfonamides; PABA b. Penicillins; Cell Wall c. Sulfonamides; Folic Acid d. Macrolides; Protein

Last Answer : c. Sulfonamides; Folic Acid

Pyrimethamine + sulfadoxine should be used as a: A. Clinical curative in areas with chloroquine resistant malaria B. Clinical curative in areas without chloroquine resistance among P. falciparum C. Prophylactic in areas with or without chloroquine resistance D. All of the above

Description : Pyrimethamine + sulfadoxine should be used as a: A. Clinical curative in areas with chloroquine resistant malaria B. Clinical curative in areas without chloroquine resistance among P. falciparum C. Prophylactic in areas with or without chloroquine resistance D. All of the above

Last Answer : A. Clinical curative in areas with chloroquine resistant malaria

elect the drug/combination that you will prescribe as a prophylactic to a resident of non-endemic area who got posted for 6 months to an endemic area with low degree chloroquine resistance among P. falciparum: A. Quinine B. Proguanil + Chloroquine C. Pyrimethamine + Sulfadoxine D. Artemisinin

Description : elect the drug/combination that you will prescribe as a prophylactic to a resident of non-endemic area who got posted for 6 months to an endemic area with low degree chloroquine resistance among P. falciparum: A. Quinine B. Proguanil + Chloroquine C. Pyrimethamine + Sulfadoxine D. Artemisinin

Last Answer : B. Proguanil + Chloroquine

The primary reason why chloramphenicol is not being used as the first line drug for typhoid fever in most areas is: A. Toxic potential of chloramphenicol B. Delayed defervescence with chloramphenicol C. Delayed bacteriological cure with chloramphenicol D. Spread of chloramphenicol resistance among S. typhi

Description : The primary reason why chloramphenicol is not being used as the first line drug for typhoid fever in most areas is: A. Toxic potential of chloramphenicol B. Delayed defervescence with ... C. Delayed bacteriological cure with chloramphenicol D. Spread of chloramphenicol resistance among S. typhi

Last Answer : D. Spread of chloramphenicol resistance among S. typhi

The most important mechanism of concurrent acquisition of multidrug resistance among bacteria is: A. Mutation B. Conjugation C. Transduction D. Transformation

Description : The most important mechanism of concurrent acquisition of multidrug resistance among bacteria is: A. Mutation B. Conjugation C. Transduction D. Transformation

Last Answer : B. Conjugation

Acute renal failure (ARF) may be caused by all of the following except (a) Acute tubular necrosis (ATN) due to drug therapy (e.g., aminoglycosides, contrast media) (b) Severe hypotension or circulatolry collapse (c) Decreased cardiac output, as from congestive heart failure (d) Hemolysis, myoglobinuria (e) Hyperkalemia

Description : Acute renal failure (ARF) may be caused by all of the following except (a) Acute tubular necrosis (ATN) due to drug therapy (e.g., aminoglycosides, contrast media) (b) Severe hypotension ... (c) Decreased cardiac output, as from congestive heart failure (d) Hemolysis, myoglobinuria (e) Hyperkalemia

Last Answer : Ans: E

Which one of the following statements about “one daily” dosing with aminoglycosides is false ? (a) It is convenient for outpatient therapy (b) Adjustment of dosage is less important in renal insufficiency (c) Less nursing time is required (d) It is often less toxic than conventional (multiple)dosing regimens (e) Under-dosing is less of a problem

Description : Which one of the following statements about one daily dosing with aminoglycosides is false ? (a) It is convenient for outpatient therapy (b) Adjustment of dosage is less important in renal ... often less toxic than conventional (multiple)dosing regimens (e) Under-dosing is less of a problem

Last Answer : Ans: B

The following statement is not correct for uremic patients: A. Attainment of steady-state plasma concentration of drugs eliminated through the kidney is hastened B. Pethidine can cause seizures C. Diazepam produces exaggerated CNS depression D. Tetracyclines further raise blood urea level

Description : The following statement is not correct for uremic patients: A. Attainment of steady-state plasma concentration of drugs eliminated through the kidney is hastened B. Pethidine can cause seizures C. Diazepam produces exaggerated CNS depression D. Tetracyclines further raise blood urea level

Last Answer : A. Attainment of steady-state plasma concentration of drugs eliminated through the kidney is hastened

The following statement is not correct for uremic patients: A. Attainment of steady-state plasma concentration of drugs eliminated through the kidney is hastened B. Pethidine can cause seizures C. Diazepam produces exaggerated CNS depression D. Tetracyclines further raise blood urea level

Description : The following statement is not correct for uremic patients: A. Attainment of steady-state plasma concentration of drugs eliminated through the kidney is hastened B. Pethidine can cause seizures C. Diazepam produces exaggerated CNS depression D. Tetracyclines further raise blood urea level

Last Answer : A. Attainment of steady-state plasma concentration of drugs eliminated through the kidney is hastened

Choose the correct statement about rifampin: A. It is the most active drug on slow growing tubercle bacilli B. Its antitubercular efficacy is lower than that of isoniazid C. It is active against many atypical mycobacteria D. It does not effectively cross blood-CSF barrier

Description : Choose the correct statement about rifampin: A. It is the most active drug on slow growing tubercle bacilli B. Its antitubercular efficacy is lower than that of isoniazid C. It is active against many atypical mycobacteria D. It does not effectively cross blood-CSF barrier

Last Answer : C. It is active against many atypical mycobacteria

Which of the following represents the correct combination without any exception ? Characteristics Class (a) Sucking and circular mouth; jaws absent, integument without scales; paired appendages. Cyclostomata (b) Body covered with feathers; skin moist and glandular, fore- limbs form wings; (c) Mammary gland; hair on body; pinnae; two pairs of limbs. Mammalia (d) Mouth ventral; gills without operculum; skin with placoid scales; persistent notochord. Chondrichthyeslungs with air sacs. Aves

Description : Which of the following represents the correct combination without any exception ? Characteristics Class (a) Sucking and circular mouth; jaws absent, integument without scales; paired ... Mouth ventral; gills without operculum; skin with placoid scales; persistent notochord. Chondrichthyes

Last Answer : (c) Mammary gland; hair on body; pinnae; two pairs of limbs. Mammalia

Proguanil is not used as a clinical curative in malaria because: A. Its schizontocidal action is slow B. Resistance to proguanil is widespread C. It is more toxic than chloroquine D. All of the above are correct

Description : Proguanil is not used as a clinical curative in malaria because: A. Its schizontocidal action is slow B. Resistance to proguanil is widespread C. It is more toxic than chloroquine D. All of the above are correct

Last Answer : A. Its schizontocidal action is slow

Choose the correct statement about the action of nitrates on coronary vessels: A. They mitigate angina pectoris by increasing total coronary flow B. They preferentially dilate conducting arteries without affecting resistance arterioles C. They preferentially dilate autoregulatory arterioles without affecting the larger arteries D. They increase subepicardial blood flow without affecting subendocardial blood flow

Description : Choose the correct statement about the action of nitrates on coronary vessels: A. They mitigate angina pectoris by increasing total coronary flow B. They preferentially dilate conducting ... the larger arteries D. They increase subepicardial blood flow without affecting subendocardial blood flow

Last Answer : B. They preferentially dilate conducting arteries without affecting resistance arterioles

Choose the correct statement(s) about dofetilide: A. It is a pure class III antiarrhythmic B. It has no adrenergic/cholinergic receptor blocking property C. It selectively depresses the rapid component of delayed rectifier K+ current in myocardial fibres D. All of the above

Description : Choose the correct statement(s) about dofetilide: A. It is a pure class III antiarrhythmic B. It has no adrenergic/cholinergic receptor blocking property C. It selectively depresses the rapid component of delayed rectifier K+ current in myocardial fibres D. All of the above

Last Answer : D. All of the above

Tetracyclines inhibit binding of amino acyl tRNAs to (A) 30 S ribosomal subunits (B) 40 S ribosomal subunits (C) 50 S ribosomal subunits (D) 60 S ribosomal subunits

Description : Tetracyclines inhibit binding of amino acyl tRNAs to (A) 30 S ribosomal subunits (B) 40 S ribosomal subunits (C) 50 S ribosomal subunits (D) 60 S ribosomal subunits

Last Answer : Answer : A

Chloramphenicol is more active than tetracyclines against (a) Bateroides fragilis (b) Treponema pallidum (c) Streptococci (d) Staphylococci

Description : Chloramphenicol is more active than tetracyclines against (a) Bateroides fragilis (b) Treponema pallidum (c) Streptococci (d) Staphylococci

Last Answer : Ans: A

Tetracyclines are still the first choice drugs for the following disease. (a) Granuloma linguinale (b) Chancroid (c) Syphilis (d) Gonorrhoea in patients allergic to penicillin

Description : Tetracyclines are still the first choice drugs for the following disease. (a) Granuloma linguinale (b) Chancroid (c) Syphilis (d) Gonorrhoea in patients allergic to penicillin

Last Answer : Ans: A

Compared to older tetracyclines, doxycycline produces a lower incidence of superinfection diarrhoea because (a) It is completely absorbed in the small intestines so that drug concentration in the colonic contents is low (b) It is inactivated by the gut microflora (c) It is not active against the microbes of the normal gut flora (d) It is a potent tetracycline and inhibits the superinfection causing microbes as well

Description : Compared to older tetracyclines, doxycycline produces a lower incidence of superinfection diarrhoea because (a) It is completely absorbed in the small intestines so that drug concentration in the colonic ... (d) It is a potent tetracycline and inhibits the superinfection causing microbes as well

Last Answer : Ans: A

Tetracyclines interfere with a. Translation. b. Transcription. c. Dna Replication. d. Membrane Function.

Description : Tetracyclines interfere with a. Translation. b. Transcription. c. Dna Replication. d. Membrane Function.

Last Answer : a. Translation.

All the following are drugs or drug classes blocking cell wall synthesis except: a. Cephalosporins. b. Carbapenems. c. Monobactams. d. Tetracyclines.

Description : All the following are drugs or drug classes blocking cell wall synthesis except: a. Cephalosporins. b. Carbapenems. c. Monobactams. d. Tetracyclines.

Last Answer : a. Cephalosporins.

Interaction between the following pair of drugs can be avoided by making suitable adjustments: A. Levodopa and metoclopramide B. Furosemide and indomethacin C. Tetracyclines and ferrous sulfate D. Clonidine and chlorpromazine

Description : Interaction between the following pair of drugs can be avoided by making suitable adjustments: A. Levodopa and metoclopramide B. Furosemide and indomethacin C. Tetracyclines and ferrous sulfate D. Clonidine and chlorpromazine

Last Answer : C. Tetracyclines and ferrous sulfate

Clozapine is considered to be an atypical neuroleptic because: A. It has weak antidopaminergic action but high antipsychotic efficacy B. Its side effect profile is different from that of chlorpromazine C. It is not a phenothiazine derivative D. Both ‘A’ and ‘B’ are correct

Description : Clozapine is considered to be an atypical neuroleptic because: A. It has weak antidopaminergic action but high antipsychotic efficacy B. Its side effect profile is different from that of chlorpromazine C. It is not a phenothiazine derivative D. Both ‘A’ and ‘B’ are correct

Last Answer : D. Both ‘A’ and ‘B’ are correct

The parasitic element of an antenna system will A. decrease its directivity B. increase its directivity C. give the antenna unidirectional properties D. both B and C

Description : The parasitic element of an antenna system will A. decrease its directivity B. increase its directivity C. give the antenna unidirectional properties D. both B and C

Last Answer : D. both B and C

Pick out the wrong statement. (A) The mole fraction of solute is directly proportional to the molality of a 'dilute' solution (B) For a non-reacting binary mixture of ideal gases, the partial pressure distribution of both components is nonlinear in the case of steady state unimolal unidirectional diffusion (C) Azeotropes obey Raoult's law at all temperature (D) The relative volatility of a binary mixture at the Azeotropic composition is 1

Description : Pick out the wrong statement. (A) The mole fraction of solute is directly proportional to the molality of a 'dilute' solution (B) For a non-reacting binary mixture of ideal gases, the partial ... at all temperature (D) The relative volatility of a binary mixture at the Azeotropic composition is 1

Last Answer : (C) Azeotropes obey Raoult's law at all temperature

The following is true of multidrug therapy of leprosy except: A. It has been highly successful in paucibacillary but not in multibacillary cases B. Relapse rate is very low in both paucibacillary and multibacillary cases C. No resistance to rifampin develops despite its use once a month D. Prevalence of lepra reaction is not higher compared to dapsone monotherapy

Description : The following is true of multidrug therapy of leprosy except: A. It has been highly successful in paucibacillary but not in multibacillary cases B. Relapse rate is very low in both paucibacillary ... use once a month D. Prevalence of lepra reaction is not higher compared to dapsone monotherapy

Last Answer : A. It has been highly successful in paucibacillary but not in multibacillary cases

As an antitubercular drug, isoniazid has the following advantages except: A. It is tuberculocidal B. It acts on both extra and intracellular bacilli C. Tubercle bacilli do not develop resistance against it D. It is cheap

Description : As an antitubercular drug, isoniazid has the following advantages except: A. It is tuberculocidal B. It acts on both extra and intracellular bacilli C. Tubercle bacilli do not develop resistance against it D. It is cheap

Last Answer : C. Tubercle bacilli do not develop resistance against it

Select the vasodilator that is administered only by slow intravenous infusion and dilates both resistance as well as capacitance vessels: A. Minoxidil B. Diazoxide C. Sodium nitroprusside D. Glyceryl trinitrate

Description : Select the vasodilator that is administered only by slow intravenous infusion and dilates both resistance as well as capacitance vessels: A. Minoxidil B. Diazoxide C. Sodium nitroprusside D. Glyceryl trinitrate

Last Answer : C. Sodium nitroprusside

Aminoglycoside antibiotics have the following property common to all members: A. They are primarily active against aerobic gram negative bacilli B. They are more active in acidic medium C. They readily enter cells and are distributed in total body water D. They are nearly completely metabolized in liver

Description : Aminoglycoside antibiotics have the following property common to all members: A. They are primarily active against aerobic gram negative bacilli B. They are more active in acidic medium C. They ... cells and are distributed in total body water D. They are nearly completely metabolized in liver

Last Answer : A. They are primarily active against aerobic gram negative bacilli

Alkylating agents exert cytotoxic action by inducing: A. Breakage of DNA strand B. Cross linking of DNA strands C. Abnormal pairing of purine and pyrimidine bases D. All of the above

Description : Alkylating agents exert cytotoxic action by inducing: A. Breakage of DNA strand B. Cross linking of DNA strands C. Abnormal pairing of purine and pyrimidine bases D. All of the above

Last Answer : D. All of the above