Description : Which of the following statements regarding the transmission of infectious agents through blood transfusions is/are true? A. The transmission rates for human immunodeficiency virus (HIV) ... patients (such as patients undergoing transplantation) should receive specially screened blood products.
Last Answer : Answer: ABCD DISCUSSION: The incidence of both HIV and hepatitis transmitted via blood transfusions has been steadily decreasing since the 1980s. This is related to improved ... , severely compromised patients such as those undergoing transplantation should receive CMV-negative blood products
Description : The following statement(s) is/are true concerning newer detection methods of systemic infection. a. Enzyme-linked immunosorbent assay (ELISA) is a rapid immunologic assay used for ... detected using advanced molecular techniques include cytomegalovirus (CMV) and human immunodeficiency virus (HIV)
Last Answer : Answer: a, b, c, d Although the classic detection of infection based on clinical signs of infection and bacterial culture remain the most common clinical tools, increasing ... including CMV and HIV. Furthermore, preliminary investigations into possible detection of fungal pathogens are underway
Description : Diagnostic DNA probes have been developed for A- Mycobacterium tuberculosis B- Hepatitis B virus C- Human immunodeficiency virus D- all of the above
Last Answer : - all of the above
Description : Ganciclovir is mainly used for the treatment of infection caused by (A) Cytomegalovirus (B) Candida albicans (C) Herpes zoster virus (D) Hepatitis B virus
Last Answer : Ans. A & C
Description : The virus directed reverse transcriptase enzyme is inhibited by: A. Amantadine B. Zidovudine C. Vidarabine D. Acyclovir
Last Answer : B. Zidovudine
Description : Choose the correct statement about famciclovir: A. It is active against acyclovir resistant strains of herpes simplex virus B. It does not need conversion to an active metabolite C. It is used orally to treat genital herpes simplex D. It is the drug of choice for cytomegalovirus retinitis
Last Answer : C. It is used orally to treat genital herpes simplex
Description : What is true about human interferon α: A. It is used to treat HIV infection B. It is used to treat Kaposi‘s sarcoma in AIDS patients C. It is curative for hepatitis B virus infection D. It is active orally
Last Answer : B. It is used to treat Kaposi‘s sarcoma in AIDS patients
Description : The ______ can cause serious birth defects including mental impairment. a. Mononucleosis b. Cytomegalovirus c. Polio d. Hepatitis C
Last Answer : a. Mononucleosis
Description : Select the correc: combination of drugs for the treatment of patients suffering from Hepatitis C : (A) Interferon with Ribavirin (B) Interferon with Zidovudine (C) Interferon with Stavudine (D) Interferon with Lamivudine
Last Answer : (B) Interferon with Zidovudine
Description : Choose the correct statement(s) about retroviral protease inhibitors: A. They act at an early step in HIV replication B. They are more active in inhibiting HIV than zidovudine C. They inhibit CYP3A4 and interact with many other drugs D. Both 'B' and 'C' are correct
Last Answer : D. Both 'B' and 'C' are correct
Description : Select the drug that is active against both HIV and hepatitis B virus: A. Lamivudine B. Indinavir C. Didanosine D. Efavirenz
Last Answer : A. Lamivudine
Description : An AIDS patient treated with zidovudine + lamivudine + nelfinavir developed intolerable adverse effects. Then: A. Dose of all three drugs should be reduced to half B. All three drugs should be stopped or substituted simultaneously C. The drugs should be stopped one by one D. Two drugs sh
Last Answer : B. All three drugs should be stopped or substituted simultaneously
Description : According to current guidelines, previously untreated symptomatic HIV patients should be treated with: A. Zidovudine alone B. Zidovudine + zalcitabine C. Zidovudine + indinavir D. Any two nucleoside reverse transcriptase inhibitors + one protease inhibito
Last Answer : D. Any two nucleoside reverse transcriptase inhibitors + one protease inhibitor
Description : The following anti-HIV drug should not be combined with zidovudine because of mutual antagonism: A. Stavudine B. Lamivudine C. Nevirapine D. Ritonavir
Last Answer : A. Stavudine
Description : Though the following drug reduces HIV titre, it is used only to treat associated cytomegalovirus infection in AIDS patients: A. Didanosine B. Foscarnet C. Acyclovir D. Saquinavir
Last Answer : B. Foscarnet
Description : Currently, monotherapy with zidovudine is recommended for: A. Asymptomatic HIV positive subjects with CD4 cell count more than 200/μl B. Asymptomatic HIV positive subjects with CD4 cell count less than 200/μl C. HIV positive subjects with opportunistic infection D. None of the above
Last Answer : D. None of the above
Description : Ganciclovir is preferred over acyclovir in the following condition: A. Herpes simplex keratitis B. Herpes zoster C. Chickenpox D. Cytomegalovirus retinitis in AIDS patient
Last Answer : D. Cytomegalovirus retinitis in AIDS patients
Description : The fecal-oral route is the mode of transmission for the _____. a. Hepatitis A virus. b. Hepatitis B virus. c. Hepatitis A and B viruses. d. All hepatitis viruses.
Last Answer : b. Hepatitis B virus.
Description : These viruses multiply first in the tonsils and then the lymphoid tissues of the gastrointestinal tract. a. Rabies virus b. Rotavirus c. Polio virus d. Hepatitis A virus
Last Answer : c. Polio virus
Description : A long thread-Like RNA virus is typical of the viruses. a. hepatitis C b. Ebola c. polio d. West Nile
Last Answer : b. Ebola
Description : Which of the following infection(s) can be diagnosed by the use of polymerase chain reaction? A- HIV-1 and HIV-2 viruses B- Hepatitis B virus C- Mycobacterium tuberculosis D- All of these
Last Answer : All of these
Description : Which of the following hepatitis viruses is not RNA virus? A- Hepatitis A virus B- Hepatitis B virus C- Hepatitis E virus D- Hepatitis G virus
Last Answer : Hepatitis B virus
Description : 10. What are the various routes by which trans-mission of human immunodeficiency virus takes place? -Science
Last Answer : Various routes by which transmission of human immunodeficiency virus takes place are (i) Illicit sexual contact. (ii) Sexual contact with multiple partners. (iii) Transfusion of the blood of infected person. (iv) Intravenous drug users that shares needles are at high risk of contracting AIDS.
Description : AIDS is caused by Human Immunodeficiency Virus (HIV), What is this? -Do You Know?
Last Answer : answer:
Description : Human immunodeficiency virus destroys (A) Cytotoxic T cells (B) Helper T cells (C) B cells (D) Plasma cells
Last Answer : Answer : B
Description : AIDS is caused by the Human Immunodeficiency Virus (HIV) The transmission of HIV infection generally occurs through. (a) eating contaminated food and water (b) transfusion of contaminated blood and blood products (c) inhaling polluted air (d) shaking hand with infected person
Last Answer : Ans:(b)
Description : AIDS is caused by Human Immunodeficiency Virus (HIV), What is this?
Last Answer : Retro virus
Description : 8. . Human immunodeficiency virus (HIV) contains (a) reverse transcriptase (ii) DNA (iii) double-stranded RNA (iv) nuclear membrane
Last Answer : (a) reverse transcriptase
Description : Which of the following viruses is most susceptible to acyclovir: A. Herpes simplex type I virus B. Herpes simplex type II virus C. Varicella-zoster virus D. Epstein-Barr virus
Last Answer : A. Herpes simplex type I virus
Description : Indicate the drug(s) that is/are used to treat chronic hepatitis B: A. Human interferon α B. Lamivudine C. Amantadine D. Both 'A' and 'B'
Last Answer : D. Both 'A' and 'B'
Description : Mononucleosis is an infection of________ cells by the _____. a. T; cytomegalovirus b. B; Epstein-Barr virus c. Lung; cytomegalovirus d. red blood; Epstein.Barr virus
Last Answer : d. red blood; Epstein.Barr virus
Description : Which of the following microorganisms is known to cause retinitis in people with HIV/AIDS? a) Cytomegalovirus Cytomegalovirus is a species-specific herpes virus. b) Cryptococcus neoformans Cryptococcus neoformans is ... is thought to be protozoan but believed to be a fungus based on its structure.
Last Answer : a) Cytomegalovirus Cytomegalovirus is a species-specific herpes virus.
Description : Which one of the following drugs is most effective in preventing transmission of HIV virus from the mother to the foetus? (A) Lamivudine (B) Zidovudine (C) Indinavir (D) Ribavirin
Last Answer : (B) Zidovudine
Description : The distinctive feature of terbinafine is: A. It is highly effective in histoplasmosis B. It can be used topically as well as orally for dermatophytosis C. It inhibits Mucor and Aspergillus as well D. Applied intravaginally it cures both candida as well as trichomonas vaginitis
Last Answer : B. It can be used topically as well as orally for dermatophytosis
Description : Chloramphenicol inhibits bacterial protein synthesis by: A. Binding to 30S ribosome and inhibiting attachment of aminoacyl tRNA B. Binding to 50S ribosome and preventing peptide bond formation C. Binding to ... chain D. Binding to both 30S and 50S ribosome and inducing misreading of mRNA code
Last Answer : B. Binding to 50S ribosome and preventing peptide bond formation
Description : Cyclic nucleotides exert the following action on salt transport across intestinal mucosal cells: A. Both cyclic AMP and cyclic GMP enhance Cland HCO3 - secretion B. Cyclic AMP enhances but cyclic GMP ... Cl- reabsorption D. Both cyclic AMP and cyclic GMP enhance Na+ and Cl- reabsorption
Last Answer : A. Both cyclic AMP and cyclic GMP enhance Cland HCO3 – secreti
Description : The positive inotropic action of digoxin takes several hours to develop because: A. Binding of digoxin to Na+K+ATPase is slow B. After Na+K+ATPase inhibition by digoxin, Ca2+ loading of myocardial ... +ATPase through modification of gene function which takes time D. Both A' and B' are correc
Last Answer : D. Both ‘A’ and ‘B’ are correct
Description : Captopril pretreatment: A. Inhibits the pressor action of angiotensin I B. Inhibits the pressor action of angiotensin II C. Potentiates the depressor action of bradykinin D. Both ‘A’ and ‘C’ are correct
Last Answer : D. Both ‘A’ and ‘C’ are correct
Description : The most important dose dependent toxicity of dapsone is: A. Methemoglobinemia B. Haemolysis C. Hepatitis D. Dermatitis
Last Answer : B. Haemolysi
Description : The primary reason for not using ethionamide as a first line antitubercular drug is: A. It produces gastrointestinal intolerance and hepatitis B. It is only tuberculostatic and not tuberculocidal C. Ethionamide resistance has become widespread D. It has to be given by injection
Last Answer : A. It produces gastrointestinal intolerance and hepatitis
Description : The characteristic toxicity of ethambutol is: A. Hepatitis B. Visual defects C. Vestibular disturbance D. Renal damage
Last Answer : B. Visual defects
Description : Hepatitis with cholestatic jaundice occurs most frequently as an adverse reaction to the following preparation of erythromycin: A. Erythromycin base B. Erythromycin stearate C. Erythromycin estolate D. Erythromycin ethylsuccinate
Last Answer : C. Erythromycin estolate
Description : Sodium valproate should be used with caution in young children because they are particularly at risk of developing the following adverse effect: A. Hepatitis B. Loss of hair C. Anorexia D. Tremor
Last Answer : A. Hepatitis
Description : Select the drug which directly inhibits HIV-reverse transcriptase without the need for intracellular activation by phosphorylation: A. Nelfinavir B. Nevirapine C. Stavudine D. Didanosine
Last Answer : B. Nevirapine
Description : The following is true of linezolid except: A. It inhibits bacterial protein synthesis at an early step B. It is active against vancomycin resistant enterococci C. It is the drug of choice for enterococcal endocarditis D. It can be administered orally as well as by i.v. infusion
Last Answer : C. It is the drug of choice for enterococcal endocarditis
Description : Select the antibiotic which inhibits drug metabolizing isoenzyme CYP3A4 resulting in potentially fatal drug interaction with terfenadine: A. Erythromycin B. Clindamycin C. Gentamicin D. Vancomycin
Last Answer : A. Erythromycin
Description : Select the antibiotic which inhibits bacterial protein synthesis by interfering with translocation of elongating peptide chain from acceptor site back to the peptidyl site of the ribosome so that ... chain is prematurely terminated: A. Chloramphenicol B. Erythromycin C. Tetracycline D. Streptomycin
Last Answer : B. Erythromycin
Description : The following is true for gentamicin: A. It is more active in acidic medium B. It has a wide margin of safety C. It is excreted unchanged, mainly by glomerular filtration D. It primarily inhibits gram positive bacteria
Last Answer : C. It is excreted unchanged, mainly by glomerular filtration
Description : Compared to older tetracyclines, doxycycline produces a lower incidence of superinfection diarrhoea because: A. It is completely absorbed in the small intestines so that drug concentration in the colonic contents ... the microbes of the normal gut flora D. It is a potent tetracycline and inhibits
Last Answer : A. It is completely absorbed in the small intestines so that drug concentration in the colonic contents is low
Description : What is true of cefpirome: A. It is a fourth generation cephalosporin B. It easily penetrates porin channels of gram negative bacteria C. It inhibits type I β-lactamase producing enterobacteriaceae D. All of the above
Last Answer : . All of the above