Description : Which of the following is true of acarbose: A. It reduces absorption of glucose from intestines B. It produces hypoglycaemia in normal as well as diabetic subjects C. It limits postprandial hyperglycaemia in diabetics D. It raises circulating insulin levels
Last Answer : C. It limits postprandial hyperglycaemia in diabetics
Description : Metabolic effects that generally attend antiinflammatory doses of aspirin include the following except: A. Increased CO2 production B. Hepatic glycogen depletion C. Metabolic acidosis D. Compensated respiratory alkalosis
Last Answer : C. Metabolic acidosis
Description : Choose the action for which the dose of aspirin required is the lowest: A. Analgesic B. Antipyretic C. Antiinflammatory D. Antiplatelet aggregatory
Last Answer : D. Antiplatelet aggregatory
Description : The plasma half life of aspirin (along with salicylic acid released from it): A. Remains constant irrespective of dose B. Is longer for antiinflammatory doses compared to that for analgesic ... for antiinflammatory doses compared to that for analgesic dose D. Can be shortened by acidifying urine
Last Answer : B. Is longer for antiinflammatory doses compared to that for analgesic dose
Description : Intravenous injection of quinine produces: A. Rise in blood pressure B. Neuromuscular block C. Hyperglycaemia D. Hypoglycaemia
Last Answer : D. Hypoglycaemia
Description : Which of the following is seen at low (analgesic) doses of aspirin: A. Respiratory stimulation B. Increased occult blood loss in stools C. Increased cardiac output D. Hyperglycaemia
Last Answer : B. Increased occult blood loss in stools
Description : Respiratory acidosis is that in which the blood pH is low due to increased retention of carbon dioxide caused by the lowering of the respiratory frequency or by pulmonary diseases that impair ... caused by metabolic disturbances that increase the concentration of bases (alkalis) in the blood.
Last Answer : Where are the chemoreceptors that detect the acidity of the blood and trigger the respiratory compensation located?
Description : The most prominent and dose related side effect of salbutamol is: A. Rise in blood pressure B. Muscle tremor C. Hyperglycaemia D. Central nervous system stimulation
Last Answer : B. Muscle tremor
Description : What is true of nimesulide: A. It exerts antiinflammatory action by several mechanisms in addition to cyclooxygenase inhibition B. It is preferred for long-term use in rheumatoid arthritis C. It is contraindicated in aspirin intolerant asthma patients D. All of the above
Last Answer : A. It exerts antiinflammatory action by several mechanisms in addition to cyclooxygenase inhibition
Description : Which of the following is Type B ADRS? a) Hypoglycaemia caused by Insulin b) Dryness of mouth caused by Atropine c) Anaemia in patient with G6PD deficiency caused by Primaquine d) Hyperglycaemia caused by thiazide diuretics
Last Answer : c) Anaemia in patient with G6PD deficiency caused by Primaquine
Description : Which one of the following is a feature of the VIPoma syndrome? 1) Alkalosis 2) Hypoglycaemia 3) Hypokalaemia 4) Increased gastric acid seceretion 5) Provocation of VIP release by somatostatin
Last Answer : Answers-3 a, b,d,e: All opposite to what is expected. VIPOMA -Features vasoactive intestinal polypeptide secreting tumour, mainly pancreas rarely ganglioneuroblatoma (sympathetic ... -peripheral vasodilation - inhibits gastric acid secretion -potentiates acetylcholine action on salivary glands
Description : What is true of nicotinic acid as well as nicotinamide: A. Both possess vitamin B3 activity B. Both cause cutaneous vasodilatation C. Both lower plasma triglyceride and VLDL levels D. Both cause hyperglycaemia after prolonged medication
Last Answer : A. Both possess vitamin B3 activity
Description : Long-term thiazide therapy can cause hyperglycaemia by: A. Reducing insulin release B. Interfering with glucose utilization in tissues C. Increasing sympathetic activity D. Increasing corticosteroid secretion
Last Answer : A. Reducing insulin release
Description : Use of ritodrine to arrest premature labour can cause the following complications except: A. Tachycardia B. Fall in blood pressure C. Hypoglycaemia D. Pulmonary edema
Last Answer : C. Hypoglycaemia
Description : The most effective drug for prevention of stroke in atrial fibrillation patients is: A. Aspirin B. Warfarin C. Low dose subcutaneous heparin D. Digoxin
Last Answer : B. Warfarin
Description : Selective inhibition of thromboxane A2 synthesis by low dose aspirin therapy might retard the progression of: A. Pregnancy induced hypertension B. Steroid induced hypertension C. Renal hypertension D. Malignant hypertension
Last Answer : A. Pregnancy induced hypertension
Description : Choose the correct statement about aspirin: A. In an afebrile patient acute overdose of aspirin produces hypothermia B. Aspirin suppresses flushing attending large dose of nicotinic acid C. Aspirin ... acute rheumatic fever D. Long term aspirin therapy increases the risk of developing colon cancer
Last Answer : B. Aspirin suppresses flushing attending large dose of nicotinic acid
Description : component of the management of moderately severe diabetic ketoacidosis: A. Insulin B. Intravenous fluids C. Potassium chloride D. Sodium bicarbonate
Last Answer : D. Sodium bicarbonate
Description : Insulin therapy is required for the following category/ categories of type 2 diabetes mellitus patients: A. Patients with ketoacidosis B. Patients undergoing surgery C. Pregnant diabetic D. All of the above
Last Answer : D. All of the above
Description : Which of the following measures is not an essential component of the management of moderately severe diabetic ketoacidosis: A. Insulin B. Intravenous fluids C. Potassium chloride D. Sodium bicarbonate
Last Answer : . Sodium bicarbonate
Description : Choose the most suitable antihypertensive drug for a 45-year-old male company executive who has a travelling job. His blood pressure is 160/100 mm Hg, and he is a diabetic ... → rebound hypertension. Hydrochlorothiazide: May worsen diabetes; more likely to produce weakness, fatigue and impotenc
Last Answer : B. Enalapril
Description : Choose the correct statement about nateglinide: A. It is a long acting oral hypoglycaemic drug B. Taken just before a meal, it limits postprandial hyperglycaemia in type 2 diabetes mellitus C. It lowers ... 1 and type 2 diabetes mellitus D. It acts by opening K+ channels in myocytes and adipocytes
Last Answer : B. Taken just before a meal, it limits postprandial hyperglycaemia in type 2 diabetes mellitus
Description : In diabetic patients, round the clock tight control of hyperglycaemia achieved by multiple daily insulin injections or insulin pumps: A. Prevents macrovascular disease more effectively B. Is recommended ... Is associated with higher incidence of hypoglycaemic reactions D. Both A and C are correct
Last Answer : D. Both A and C are correct
Description : Which of the following is a neuroglucopenic symptom of hypoglycaemia: A. Sweating B. Palpitation C. Tremor D. Abnormal behaviour
Last Answer : D. Type 2 diabetes patients not controlled by a biguanide drug
Description : Which of the following is true of counterregulatory symptoms of insulin hypoglycaemia: A. They generally appear before neuroglucopenic symptoms B. They are accentuated after long-term insulin treatment C. They result from parasympathetic activation D. They manifest as hunger and fatigue
Last Answer : A. They generally appear before neuroglucopenic symptom
Description : The most common adverse reaction to insulin is: A. Hypoglycaemia B. Lipodystrophy C. Urticaria D. Angioedema
Last Answer : A. Hypoglycaemia
Description : Bronchodilators are useful in cough (a) Only when cough is non-productive (b) Only when cough is associated with thick sticky secretions (c) Only when reflex bronchoconstriction is associated (d) ... Rise in blood pressure (b) Muscle tremor (c) Hyperglycaemia (d) Central nervous system stimulation
Last Answer : Ans: B
Description : __________ is the common and dose related side effect of salbutamol. a) Decrease in blood pressure b) Muscle tremor c) Central nervous system stimulation d) Hyperglycaemia
Last Answer : c) Central nervous system stimulation
Description : The toxicity spectrum of aspirin does not include (a) Increased risk of encephalopathy in children with viral infections (b) Increased risk of peptic ulcers (c) Hyperprothrombinemia (d) Metabolic acidosis (e) Respiratory alkalosis
Last Answer : Ans: C
Description : The second generation sulfonylurea hypoglycaemics differ from the first generation ones in that they: A. Are more potent B. Are longer acting C. Do not lower blood sugar in nondiabetic subjects D. Are less prone to cause hypoglycaemic reaction
Last Answer : A. Are more potent
Description : Adrenergic β1 selective blockers offer the following advantages except: A. Lower propensity to cause bronchospasm B. Less prone to produce cold hands and feet as side effect C. Withdrawal is less likely to exacerbate angina pectoris D. Less liable to impair exercise capacity
Last Answer : C. Withdrawal is less likely to exacerbate angina pectoris
Description : Adrenergic β 1 selective blockers offer the following advantages except: A. Lower propensity to cause bronchospasm B. Less prone to produce cold hands and feet as side effect C. Withdrawal is less likely to exacerbate angina pectoris D. Less liable to impair exercise capacity
Description : Thioguanine differs from mercaptopurine in that: A. It is not metabolized by xanthine oxidase B. It does not cause hyperuricemia C. Its dose need not be reduced when allopurinol is given concurrently D. Both ‘A’ and ‘C’ are correc
Last Answer : D. Both ‘A’ and ‘C’ are correct
Description : The distinctive feature of nimesulide is: A. It does not inhibit prostaglandin synthesis B. It does not cause gastric irritation C. It is usually well tolerated by aspirin intolerant asthma patients D. It is not bound to plasma proteins
Last Answer : C. It is usually well tolerated by aspirin intolerant asthma patients
Description : The following is true of clofazimine except: A. It is cidal to Mycobacterium leprae B. It has additional antiinflammatory property C. It has a very long elimination half life D. It discolours skin and sweat
Last Answer : A. It is cidal to Mycobacterium leprae
Description : The following is/are true of mesalazine: A. It exerts mainly local antiinflammatory action in the lower gut B. It is a broad spectrum antidiarrhoeal drug C. It can be administered as a retention enema D. Both 'A' and 'C
Last Answer : D. Both 'A' and 'C
Description : The following statement is true about misoprostol: A. It relieves peptic ulcer pain, but does not promote ulcer healing B. It heals nonsteroidal antiinflammatory drug induced gastric ulcer not responding ... side effects than H2 blockers D. It is the most effective drug for preventing ulcer relapse
Last Answer : B. It heals nonsteroidal antiinflammatory drug induced gastric ulcer not responding to H2 blockers
Description : Antiatherosclerotic effect of which class of hypolipidemic drugs may involve additional mechanisms like improved endothelial function, reduced LDL oxidation and antiinflammatory property: A. Bile acid sequestrant resins B. Statins C. Fibrates D. Nicotinic acid
Last Answer : B. Statins
Description : Nonsteroidal antiinflammatory drugs reduce the diuretic action of furosemide by: A. Preventing prostaglandin mediated intrarenal haemodynamic actions B. Blocking the action in ascending limb of loop ... C. Enhancing salt and water reabsorption in distal tubule D. Increasing aldosterone secretion
Last Answer : A. Preventing prostaglandin mediated intrarenal haemodynamic actions
Description : Advantages of angiotensin converting enzyme inhibitors as antihypertensive include the following except: A. They tend to reverse left ventricular hypertrophy B. Their efficacy is not reduced by nonsteroidal ... . They do not worsen blood lipid profile D. They do not impair work performance
Last Answer : B. Their efficacy is not reduced by nonsteroidal antiinflammatory drugs
Description : The most important mechanism of antiinflammatory action of glucocorticoids is: A. Inhibition of lysosomal enzymes B. Restriction of recruitment of inflammatory cells at the site of inflammation C. Antagonism of action of interleukins D. Suppression of complement function
Last Answer : B. Restriction of recruitment of inflammatory cells at the site of inflammation
Description : Corticosteroids exert antiinflammatory action by inhibiting the following enzyme: A. Cyclooxygenase B. Lipoxygenase C. Phospholipase-A D. Phosphodiesterase
Last Answer : C. Phospholipase-A
Description : Budesonide is a: A. Nonsteroidal antiinflammatory drug B. High ceiling diuretic C. Inhaled corticosteroid for asthma D. Contraceptive
Last Answer : C. Inhaled corticosteroid for asthma
Description : Select the drug that is neither bronchodilator nor antiinflammatory, but has antihistaminic and mast cell stabilizing activity: A. Sodium cromoglycate B. Ketotifen C. Beclomethasone dipropionate D. Chlorpheniramine
Last Answer : B. Ketotifen
Description : Sulfinpyrazone has the following action(s): A. Antiplatelet aggregatory B. Uricosuric C. Antiinflammatory D. Both ‘A’ and ‘B’
Last Answer : D. Both ‘A’ and ‘B’
Description : The following antiinflammatory analgesic has been cleared for pediatric use: A. Indomethacin B. Ibuprofen C. Ketorolac D. Piroxicam
Last Answer : B. Ibuprofen
Description : Choose the correct statement about nefopam: A. It is a nonopioid analgesic which does not inhibit prostaglandin synthesis B. It is an orally active opioid analgesic C. It is an analgesic with potent antiinflammatory activity D. It is a preferential COX-2 inhibitor
Last Answer : A. It is a nonopioid analgesic which does not inhibit prostaglandin synthesis
Description : Which of the following is an efficacious antiinflammatory drug but a relatively weak inhibitor of cyclooxygenase: A. Nimesulide B. Paracetamol C. Ketoprofen D. Indomethacin
Last Answer : A. Nimesulide
Description : The following nonsteroidal antiinflammatory drug is a preferential cyclooxygenase-2 (COX-2) inhibitor: A. Tenoxicam B. Meloxicam C. Diclofenac sod. D. Ketoprofen
Last Answer : B. Meloxicam