Description : Which of the following is true of acarbose: A. It reduces absorption of glucose from intestines B. It produces hypoglycaemia in normal as well as diabetic subjects C. It limits postprandial hyperglycaemia in diabetics D. It raises circulating insulin levels
Last Answer : C. It limits postprandial hyperglycaemia in diabetics
Description : Antiinflammatory dose of aspirin given to diabetics is prone to cause: A. Hyperglycaemia B. Hypoglycaemia C. Ketoacidosis D. Alkalosis
Last Answer : B. Hypoglycaemia
Description : Rapid intravenous injection of clonidine causes rise in BP due to: A. Stimulation of vasomotor centre B. Release of noradrenaline from adrenergic nerve endings C. Agonistic action on vascular α2 adrenergic receptors D. Cardiac stimulation
Last Answer : C. Agonistic action on vascular α2 adrenergic receptors
Description : The typical response to intravenous injection of 5-HT in an anaesthetised animal is: A. Rise in BP B. Fall in BP C. Rise followed by brief fall in BP D. Transient fall, followed by brief rise, followed by prolonged fall in BP
Last Answer : D. Transient fall, followed by brief rise, followed by prolonged fall in BP
Description : 5 A nonvolatile, highly lipid soluble drug is metabolized at a rate of 15% per hour. On intravenous injection it produces general anaesthesia for 10 min. Which process is responsible for termination ... : A. Metabolism in liver B. Plasma protein binding C. Excretion by kidney D. Redistribution
Last Answer : D. Redistribution
Description : The most prominent and dose related side effect of salbutamol is: A. Rise in blood pressure B. Muscle tremor C. Hyperglycaemia D. Central nervous system stimulation
Last Answer : B. Muscle tremor
Description : Depolarizing neuromuscular blockers differ from competitive blockers in the following attributes except: A. They induce contraction of isolated frog rectus abdominis muscle B. Ether anaesthesia ... produces well sustained contraction D. Neostigmine does not reverse block produced by them
Last Answer : B. Ether anaesthesia intensifies block produced by them
Description : A semiconscious patient of haemorrhagic cerebral stroke has been brought to the emergency. His blood pressure is 240/120 mmHg. Select the procedure to lower his blood pressure as ... injection of hydralazine C. Intravenous infusion of sodium nitroprusside D. Intravenous injection of clonidin
Last Answer : C. Intravenous infusion of sodium nitroprussid
Description : Use of adenosine for terminating an episode of paroxysmal supraventricular tachycardia has the following advantages except: A. It does not produce any side effect B. It can be given to patients ... 1 min after bolus intravenous injection D. It is effective in patients not responding to verapamil
Last Answer : A. It does not produce any side effect
Description : A patient of acute myocardial infarction being treated in intensive care unit developed left ventricular failure with raised central venous pressure. It was decided to use glyceryl trinitrate. Which route ... suitable: A. Sublingual B. Oral C. Intravenous bolus injection D. Slow intravenous infusion
Last Answer : D. Slow intravenous infusion
Description : Select the drug which is used by intravenous infusion for emergency control of tachycardia and sudden rise in blood pressure: A. Amiodarone B. Lignocaine C. Esmolol D. Disopyramide
Last Answer : C. Esmolo
Description : Which of the following is Type B ADRS? a) Hypoglycaemia caused by Insulin b) Dryness of mouth caused by Atropine c) Anaemia in patient with G6PD deficiency caused by Primaquine d) Hyperglycaemia caused by thiazide diuretics
Last Answer : c) Anaemia in patient with G6PD deficiency caused by Primaquine
Description : ‘Red man syndrome’ has been associated with rapid intravenous injection of the following antibiotic: A. Vancomycin B. Clindamycin C. Cefoperazone D. Piperacillin
Last Answer : A. Vancomycin
Description : The following procedure for rapid lowering of BP in hypertensive urgency/emergency has been abandoned: A. Sublingual/oral nifedipine B. Intravenous glyceryl trinitrate infusion C. Intravenous sodium nitroprusside infusion D. Intravenous esmolol injection
Last Answer : A. Sublingual/oral nifedipine
Description : In an anaesthetized dog, repeated intravenous injection of ephedrine shows the phenomenon of: A. Anaphylaxis B. Tachyphylaxis C. Idiosyncrasy D. Drug resistance
Last Answer : B. Tachyphylaxis
Description : Choose the most suitable antihypertensive drug for a 45-year-old male company executive who has a travelling job. His blood pressure is 160/100 mm Hg, and he is a diabetic ... → rebound hypertension. Hydrochlorothiazide: May worsen diabetes; more likely to produce weakness, fatigue and impotenc
Last Answer : B. Enalapril
Description : Use of ritodrine to arrest premature labour can cause the following complications except: A. Tachycardia B. Fall in blood pressure C. Hypoglycaemia D. Pulmonary edema
Last Answer : C. Hypoglycaemia
Description : A nonvolatile, highly lipid soluble drug is metabolized at a rate of 15% per hour. On intravenous injection it produces general anaesthesia for 10 min. Which process is responsible for termination of ... : A. Metabolism in liver B. Plasma protein binding C. Excretion by kidney D. Redistribution
Description : Bronchodilators are useful in cough (a) Only when cough is non-productive (b) Only when cough is associated with thick sticky secretions (c) Only when reflex bronchoconstriction is associated (d) ... Rise in blood pressure (b) Muscle tremor (c) Hyperglycaemia (d) Central nervous system stimulation
Last Answer : Ans: B
Description : Choose the correct statement about nateglinide: A. It is a long acting oral hypoglycaemic drug B. Taken just before a meal, it limits postprandial hyperglycaemia in type 2 diabetes mellitus C. It lowers ... 1 and type 2 diabetes mellitus D. It acts by opening K+ channels in myocytes and adipocytes
Last Answer : B. Taken just before a meal, it limits postprandial hyperglycaemia in type 2 diabetes mellitus
Description : Which of the following is seen at low (analgesic) doses of aspirin: A. Respiratory stimulation B. Increased occult blood loss in stools C. Increased cardiac output D. Hyperglycaemia
Last Answer : B. Increased occult blood loss in stools
Description : Neuromuscular blocking drugs do not produce central actions because: A. They do not cross the blood-brain barrier B. Nicotinic receptors are not present in the brain C. They are sequestrated in the periphery by tight binding to the skeletal muscles D. They do not ionise at the brain pH
Last Answer : A. They do not cross the blood-brain barrier
Description : Pancuronium differs from tubocurarine in that: A. It is a depolarizing blocker B. Its action is not reversed by neostigmine C. It can cause rise in BP on rapid I.V. injection D. It causes marked histamine release
Last Answer : C. It can cause rise in BP on rapid I.V. injection
Description : The primary reason for not using ethionamide as a first line antitubercular drug is: A. It produces gastrointestinal intolerance and hepatitis B. It is only tuberculostatic and not tuberculocidal C. Ethionamide resistance has become widespread D. It has to be given by injection
Last Answer : A. It produces gastrointestinal intolerance and hepatitis
Description : Injection of adrenaline along with a local anaesthetic serves the following purpose: A. Lowers the concentration of the local anaesthetic to produce nerve block B. Prolongs the duration of local anaesthesia C. Increases the anaesthetised area D. Reduces the local toxicity of the local anaesthetic
Last Answer : B. Prolongs the duration of local anaesthesia
Description : What is true of nicotinic acid as well as nicotinamide: A. Both possess vitamin B3 activity B. Both cause cutaneous vasodilatation C. Both lower plasma triglyceride and VLDL levels D. Both cause hyperglycaemia after prolonged medication
Last Answer : A. Both possess vitamin B3 activity
Description : Long-term thiazide therapy can cause hyperglycaemia by: A. Reducing insulin release B. Interfering with glucose utilization in tissues C. Increasing sympathetic activity D. Increasing corticosteroid secretion
Last Answer : A. Reducing insulin release
Description : In diabetic patients, round the clock tight control of hyperglycaemia achieved by multiple daily insulin injections or insulin pumps: A. Prevents macrovascular disease more effectively B. Is recommended ... Is associated with higher incidence of hypoglycaemic reactions D. Both A and C are correct
Last Answer : D. Both A and C are correct
Description : Which of the following is a neuroglucopenic symptom of hypoglycaemia: A. Sweating B. Palpitation C. Tremor D. Abnormal behaviour
Last Answer : D. Type 2 diabetes patients not controlled by a biguanide drug
Description : Which of the following is true of counterregulatory symptoms of insulin hypoglycaemia: A. They generally appear before neuroglucopenic symptoms B. They are accentuated after long-term insulin treatment C. They result from parasympathetic activation D. They manifest as hunger and fatigue
Last Answer : A. They generally appear before neuroglucopenic symptom
Description : The most common adverse reaction to insulin is: A. Hypoglycaemia B. Lipodystrophy C. Urticaria D. Angioedema
Last Answer : A. Hypoglycaemia
Description : A patient of acute myocardial infarction being treated in intensive care unit developed left ventricular failure with raised central venous pressure. It was decided to use glyceryl trinitrate. Which route/ ... (a) Sublingual (b) Oral (c) Intravenous bolus injection (d) Slow intravenous infusion
Last Answer : Ans: D
Description : Indicate the drug that is a slow acting low efficacy blood schizontocide that should not be used as a clinical curative: A. Proguanil B. Chloroquine C. Quinine D. Mefloquine
Last Answer : A. Proguanil
Description : ostoperative muscle soreness may be a side effect of the following neuromuscular blocker: A. d-tubocurarine B. Succinylcholine C. Pancuronium D. Atracurium
Last Answer : B. Succinylcholine
Description : Which of the following is applicable to mivacurium: A. It undergoes Hoffmann elimination B. It is the shortest acting nondepolarizing neuromuscular blocker C. It is excreted unchanged by kidney D. It does not cause histamine release
Last Answer : B. It is the shortest acting nondepolarizing neuromuscular blocker
Description : The neuromuscular blocker that does not need reversal of action by neostigmine at the end of the operation is: A. d-Tubocurarine B. Doxacurium C. Pipecuronium D. Mivacurium
Last Answer : D. Mivacurium
Description : CHOOSE THE MOST APPROPRIATE RESPONSE 23.1 Which of the following drugs is a nondepolarizing neuromuscular blocker: A. Succinylcholine B. Vecuronium C. Decamethonium D. Dantrolene sodium
Last Answer : B. Vecuronium
Description : Adrenergic β2 agonists produce muscle tremor by: A. Facilitating neuromuscular transmission B. Incomplete fusion of contractile response of individual fibres C. Enhanced firing of muscle spindles D. Both (b) and (c) are correct
Last Answer : D. Both (b) and (c) are correct
Description : Intravenous furosemide promptly mitigates dyspnoea in acute left ventricular failure by: A. Producing bronchodilatation B. Causing rapid diuresis and reducing circulating blood volume C. Increasing venous capacitance and reducing cardiac preload. D. Stimulating left ventricular contractility
Last Answer : C. Increasing venous capacitance and reducing cardiac preload.
Description : Noradrenaline is administered by (a) Subcutaneous injection (b) Intramuscular injection (c) Slow intravenous infusion (d) All of the above routes
Last Answer : Ans: C
Description : A drug (200 mg dose) administered in tablet form and as intravenous injection (50 mg dose) showed AUG of 100 and 200 microgram hr/mL, respectively. The absolute availability of the drug through oral administration is : (A) 125% (B) 250 % (C) 12.5% (D) 1.25%
Last Answer : (C) 12.5%
Description : Which of the following is the LEAST to cause toxicity from local anaesthetic injection: A. Injecting in supine position B. Injecting in vascular area C. Injecting without a vasoconstrictor D. Intravenous injections
Last Answer : A. Injecting in supine position
Description : Toxicity as a result of anaesthetic solution can be seen more when: A. Injection in supine position B. Injection into vascular area C. Injection without vasoconstrictors D. Intravenous injection
Last Answer : D. Intravenous injection
Description : Noradrenaline is administered by: A. Subcutaneous injection B. Intramuscular injection C. Slow intravenous infusion D. All of the above routes
Last Answer : C. Slow intravenous infusion
Description : Select the route of administration which carries the highest risk of adversely affecting vital functions: A. Intra arterial injection B. Intrathecal injection C. Intravenous injection D. Intramuscular injection
Last Answer : C. Intravenous injection