Heparin is secreted by

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Answer :

Heparin is secreted by A. Kidney B. Blood cells C. Never cells D. Liver

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Last Answer : Heparin is a drug that prevents blood from clotting.

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Description : Assertion `:` Prothrombinase enzyme act as antiheparin Reason `:` Heparin prevent coagulation of blood in Blood vessels

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Description : Assertion: Heparin is an anticoagulant found in mammals. Reason: Heparin prevents the conversion of prothrombin to thrombin

Last Answer : Assertion: Heparin is an anticoagulant found in mammals. Reason: Heparin prevents the conversion of ... . If both Assertion & Reason are false.

Description : Which type of white blood cells are concerned with the release of histamine and the natural anticoagulant heparin ?

Last Answer : Which type of white blood cells are concerned with the release of histamine and the natural ... Eosinophils B. Monocytes C. Neutrophils D. Basophils

Description : Heparin is :-

Last Answer : Heparin is :- A. Protein B. Fat C. Carbohydrate D. Mucopolysacchride

Description : Fibronectin has binding sites for all of the following except (A) Glycophorin (B) Collagen (C) Heparin (D) Integrin receptor

Last Answer : Answer : C

Description : Heparin releasable hepatic lipase converts (A) VLDL remnants into LDL (B) Nascent HDL into HDL (C) HDL2 into HDL3 (D) HDL3 into HDL2

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Description : Hyaluronidase hydrolyses (A) Hyaluronic acid (B) Chondroitin sulphate (C) Heparin (D) Hyaluronic acid and chondroitin sulphate

Last Answer : Answer : D

Description : The following examples are important heteropolysaccharides except (A) Amylopectin (B) Heparin (C) Peptidoglycan (D) Hyaluronic acid

Last Answer : A

Description : Synovial fluid contains (A) Heparin (B) Hyaluronic acid (C) Chondroitin sulphate (D) Keratin sulphate

Last Answer : B

Description : N–Acetylglucosamnine is present in (A) Hyaluronic acid (B) Chondroitin sulphate (C) Heparin (D) All of these

Last Answer : A

Description : A heteropolysacchraide among the following is (A) Inulin (B) Cellulose (C) Heparin (D) Dextrin

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Description : α–D–Glucuronic acid is present in (A) Hyaluronic acid (B) Chondroitin sulphate (C) Heparin (D) All of these

Last Answer : C

Description : The glycosaminoglycan which does not contain uronic acid is (A) Hyaluronic acid (B) Heparin (C) Chondroitin sulphate (D) Dermatan sulphate

Last Answer : B

Description : There are a number of hypercoaguable states which can be associated with arterial or venous thrombosis and embolic phenomenon. These include: a. Heparin-associated thrombocytopenia b. Antithrombin III deficiency c. Von Willebrand disease d. Vitamin C deficiency

Last Answer : Answer: a, b A number of hypercoaguable states are present. These include heparin-associated thrombocytopenia in which a heparin-dependent platelet antibody causes aggregation of ... soft tissue increasing vascular permeability and fragility resulting in the potential for bleeding disorders

Description : As thrombin generation proceeds, the body has natural anticoagulant systems opposing further thrombus formation. Natural anticoagulants include: a. Tissue plasminogen activator (TPA) b. Antithrombin III c. Activated protein C d. Heparin cofactor II

Last Answer : Answer: b, c, d Just as thrombin generation is the key to coagulation, antithrombin III is the most central anticoagulant proteins. This glycoprotein binds to thrombin, preventing its removal of ... in the body. Therefore, TPA is part of the fibrinolytic system rather than a natural anticoagulant

Description : Which of the following statement(s) is/are true concerning the results of a National Institute of Health Consensus Conference on venous thrombosis and low-dose heparin prophylaxis? a. The odds of ... treated with low-dose heparin d. There was no difference in the incidence of bleeding complications

Last Answer : Answer: a, b, c In a metaanalysis of 70 randomized trials in 16,000 patients comparing low-dose heparin prophylaxis with standard therapy, the odds of developing deep venous thrombosis ... Similarly, the effectiveness of prophylaxis was not influenced by either two or three times daily dosage

Description : External pneumatic compression has been advocated for the prevention of deep venous thrombosis during operative procedures. Which of the following statement(s) concerning the use of external pneumatic ... includes through the operation and for at least several days in the postoperative period

Last Answer : Answer: b, c, d In many well-controlled studies of venous prophylaxis, intermittent pneumatic compression has been found to be as effective as low-dose heparin therapy. In addition to augmentation ... be used through the operation and for at least five days in the face or prolonged immobilization

Description : Tests of coagulation are used to monitor anticoagulation treatment and detect intrinsic abnormalities in coagulation. Which of the following statement(s) is/are true concerning ... is used to monitor heparin levels intraoperatively during cardiovascular and peripheral vascular operations

Last Answer : Answer: a, c, d Coagulation tests include prothrombin time (PT), which measures the intrinsic and extrinsic pathways of fibrinogen production and is the most common method for ... more while for peripheral vascular applications, values of 250 seconds or greater are considered appropriate

Description : Mini-dose heparin has been shown to be useful in the prophylaxis of postoperative venous thrombosis. Mechanism(s) by which low-dose heparin is/are thought to protect against venous ... aggregation and subsequent platelet release action d. A mild prolongation of activated partial thromboplastin time

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Description : Antithrombin III deficiency is a commonly observed hypercoaguable state. Which of the following statement(s) is/are true concerning this condition? a. A patient with this deficiency usually ... involves acutely the administration of fresh frozen plasma followed by long-term treatment with Coumadin

Last Answer : Answer: a, b, c, d Antithrombin III deficiency accounts for about 2% of venous thrombotic event. This deficiency has been described in patients with pulmonary embolism, mesenteric venous ... is established, fresh frozen plasma should be administered followed by long-term treatment with Coumadin

Description : Which of the following statement(s) is/are true concerning heparin-associated thrombocytopenia? a. Heparin-associated thrombocytopenia occurs only in the face of over anticoagulation with heparin b. ... d. Heparin-associated thrombocytopenia may be seen within hours of initiation of heparin therapy

Last Answer : Answer: b, c Heparin-associated thrombocytopenia occurs in 0.6% to 30% of patients who receive heparin, although severe thrombocytopenia (platelet counts less than 100,000) is seen in ... as coating on pulmonary artery catheters or low rate infusion into arterial catheters may cause this syndrome

Description : Which of the following statement(s) concerning laboratory studies used in monitoring a patient with intravenous heparinization is/are correct? a. The platelet count should be followed because of the ... serum creatinine should be measured daily to allow adjustments in dose based on renal function

Last Answer : Answer: a, c In monitoring the effect of heparin, an activated partial thromboplastin time (aPTT) of 1.5 control or a thrombin clotting time (TCT) of 2 times control reflects adequate ... system. Therefore the dose of heparin need not be adjusted in cases of liver or renal dysfunction

Description : When compared to unfractionated heparin, low molecular weight heparins have (a) Preferential binding affinity to factor Xa relative to Iia (thrombin) (b) Shorter half-lives (c) Dose – dependent renal clearance

Last Answer : Ans: A

Description : Unfractionated heparin binds to antithrombin III and inactivates clotting factor(s) (a) Xa (b) Ixa (c) Iia (d) All of the above (e) None of the above

Last Answer : Ans: D

Description : The termination of heparin activity by protamine sulfate is due to (a) A chelating action (b) The inhibition of gastrointestinal absorption of heparin (c) The displacement of heparin-plasma protein binding (d) An acid-base interaction (e) The prothrombin-like activity of protamine

Last Answer : Ans: D

Description : Blood does not coagulate inside the body due to the presence of (a) haemoglobin (b) heparin (c) fibrin (d) plasma

Last Answer : Ans:(b)

Description : What are anticoagulants? What are the practical applications of anticoagulants, like heparin, in Medicine?

Last Answer : Anticoagulants are substances that block the clotting reactions and thus stop the coagulation process. Ordinarily there are anticoagulants circulating in the plasma since under normal conditions the ... the formation of thrombus inside blood vessels of patients facing increased thrombotic risk.

Description : Blood does not clot in the blood vessels due to the presence of – (1) Thrombin (2) Fibrinogen (3) Heparin (4) Prothrombin

Last Answer : (3) Heparin Explanation: There are two major facets of the clotting mechanism — the platelets, and the thrombin system. The thrombin system consists of several blood proteins that, when bleeding occurs, become activated.

Description : Blood does not coagulate inside the body due to the presence of – (1) Plasma (2) Haemoglobin (3) Heparin (4) Fibrin

Last Answer : (3) Heparin Explanation: Heparin is a naturally-occurring anticoagulant produced by basophils and mast cells. Heparin acts as an anticoagulant, preventing the formation of clots and extension of existing clots ... is present in the walls of blood vessels where it doesn't allow blood to clot.

Description : Which is the anticoagulant substance in blood? (1) Fibrinogen (2) Heparin (3) Thrombin (4) Globin

Last Answer : (2) Heparin Explanation: Heparin, a highly sulfated glycosaminoglycan, is widely used as an inject able anticoagulant, and has the highest negative charge density of any known ... because blood anti-coagulation is achieved mostly by heparin sulfate proteoglyeans derived from endothelial cells.

Description : Secretion of Serotonin, heparin and histamine is the function of

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Last Answer : prostaglandin-2 - vasodilatation

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Last Answer : thrombin converts fibrinogen to fibrin

Description : You are required to draw blood from a patient and to keep it in a test tube for analysis of blood corpuscles and plasma. You are also provided with the following four types of test tubes ... bicarbonate (b) Chilled test tube (c) Test tube containing heparin (d) Test tube containing sodium oxalate

Last Answer : (a) Test tube containing calcium bicarbonate

Description : Which type of white blood cells are concerned with the release of histamine and the natural anticoagulant heparin? (a) Eosinophils (b) Monocytes (c) Neutrophils (d) Basophils

Last Answer : d) Basophils

Description : Mast cells of connective tissue contain (a) vasopressin and relaxin (b) heparin and histamine (c) heparin and calcitonin (d) serotonin and melanin.

Last Answer : (b) heparin and histamine

Description : Cytotoxic T cells release which 2 toxic proteins as they fight target cells? a. histamine and heparin b. perforin and granzymes c. interleukin and interferon d. lysozymes and cytokines

Last Answer : b. perforin and granzymes

Description : To ensure patency of central venous line ports, dilute heparin flushes are used in which of the following situations? a) Daily when not in use Daily instillation of dilute heparin flush when a port ... the line is discontinued Heparin flush of ports is not necessary if a line is to be discontinued.

Last Answer : a) Daily when not in use Daily instillation of dilute heparin flush when a port is not in use will maintain the port.

Description : The antidote to heparin is a) protamine sulfate. Protamine sulfate, in the appropriate dosage, acts quickly to reverse the effects of heparin. b) vitamin K. Vitamin K is the antidote to ... and symptoms of medicationinduced narcosis. d) Ipecac. Ipecac is an emetic used to treat some poisonings.

Last Answer : a) protamine sulfate. Protamine sulfate, in the appropriate dosage, acts quickly to reverse the effects of heparin.

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Last Answer : a) Protamine sulfate Protamine sulfate is known as the antagonist to heparin.

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Last Answer : a) 1.5 to 2 The amount of heparin administered is based on aPTT results, which should be obtained in follow-up to any alteration of dosage.

Description : the best to give as DVT prophylaxis post surgery which is cost effective, safe with high efficacy: a) LMWH b) Unfractioned Heparin

Last Answer : a) LMWH

Description : hematological disease occurs in children treated with heparin and fresh frozen plasma what is the disease : A)hemophilia A B)hemophilia B C )VON WILL brand disease d)DIC thrombosis

Last Answer : d)DIC thrombosis

Description : Which of the following is not true about warfarin, a. INR of 3 is enough to start any extraction. b. Affects extrinsic system and increases prothrombin time. c. Heparin can be given subcutaneously ... rapidly. d. It takes at least 12 hours for Vitamin K to reverse the effects of coumarin.

Last Answer : d. It takes at least 12 hours for Vitamin K to reverse the effects of coumarin.

Description : Which of the following is not true about warfarin, ** A. INR of 3 is enough to start any extraction B. Affects extrinsic system and decreases prothrombin time C. Heparin can be given subcutaneously and acts rapidly D. It takes up to 12 hours for Vitamin K to reverse the effects of warfarin

Last Answer : B. Affects extrinsic system and decreases prothrombin time

Description : Patient on anti-coagulant therapy requires an extraction to be performed. Which of the following is NOT true: A. Minor post operative bleedings can be reduced somehow by using tranexamic acid B. ... takes at least 8 hours for heparin to take effects D. Heparin should be administered sub-cutaneous

Last Answer : C. It takes at least 8 hours for heparin to take effects

Description : Hydroxyethyl starch is a: A. Plasma expander B. Haemostatic C. Heparin substitute D. Bile acid sequestrant

Last Answer : A. Plasma expander