Which antimicrobial drug is suitable for treatment of both tuberculosis and leprosy? -Do You Know?

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Description : Which antimicrobial drug is suitable for treatment of both tuberculosis and leprosy?

Last Answer : Rifamcin

Description : Apart from its use in tuberculosis and leprosy, rifampin is a first line drug for the following infective disease: A. Toxoplasmosis B. Brucellosis C. Donovanosis D. Leishmaniasis

Last Answer : B. Brucellosis

Description : BCG is vaccine meant for protection against which of the following diseases? (1) Mumps (2) Tuberculosis (3) Leprosy (4) Tetanus

Last Answer : (2) Tuberculosis Explanation: Bacillus Calmette-Guerin (BCG) vaccine is a vaccine primarily used against tuberculosis. The vaccine was originally developed from Mycobacterium bovis which is commonly found ... of Essential Medicines, the most effective and safe medicines needed in a health system,

Description : BCG is vaccine meant for protection against which of the following diseases? (1) Mumps (2) Tuberculosis (3) Leprosy (4) Tetanus

Last Answer : (2) Tuberculosis Explanation: Bacillus Calmette-Guérin (BCG) vaccine is a vaccine primarily used against tuberculosis. The vaccine was originally developed from Mycobacterium bovis which is commonly found in cows.

Description : BCG immunization is for - (1) Measles (2) Tuberculosis (3) Diphtheria (4) Leprosy

Last Answer : (2) Tuberculosis Explanation: Bacillus Calmette-Guerin (BCG) is a vaccine against tuberculosis that is prepared from a strain of the attenuated (weakened) live bovine tuberculosis bacillus, ... subcultured in an artificial medium for 13 years, and also prepared from Mycobacterium tuberculosis.

Description : Penicillins are useful in treating a. Gram-positive infections. b. Leprosy. c. Gram-negative infections. d. Tuberculosis.

Last Answer : a. Gram-positive infections.

Description : Which disease is NOT caused by a bacteria? a) Tetanus b) Tuberculosis c) Leprosy d) AIDS

Last Answer : ANSWER: D -- AIDS

Description : BCG is vaccine meant for protection against which of the following diseases? (1) Mumps (2) Tuberculosis (3) Leprosy (4) Tetanus

Last Answer : Tuberculosis

Description : BCG immunization is for (1) Measles (2) Tuberculosis (3) Diphtheria (4) Leprosy

Last Answer : Tuberculosis

Description : Which of the following is not likely to be the cause of failure of antimicrobial therapy of an acute infection: A. Improper selection of drug and dose B. Acquisition of resistance during treatment C. Failure to drain the pus D. Uncontrolled diabetes mellitus

Last Answer : B. Acquisition of resistance during treatment

Description : The WHO guidelines for treatment of tuberculosis with short course chemotherapy under the DOTS strategy categorise patients on the basis of the following: A. Site and severity of the disease B. Sputum smear positivity/negativity C. History of earlier antitubercular drug use D. All of the above

Last Answer : D. All of the above

Description : he multidrug therapy of leprosy is superior to monotherapy on the following account(s): A. It prevents emergence of dapsone resistance B. It is effective in cases with primary dapsone resistance C. It shortens the total duration of drug therapy and improves compliance D. All of the above

Last Answer : D. All of the above

Description : Combination therapy with two (or more) antimicrobials is superior to monotherapy with any single effective drug in case of the following diseases except: A. Typhoid fever B. Leprosy C. AIDS D. Subacute bacterial endocarditis

Last Answer : A. Typhoid fever

Description : Which type of antimicrobial drug combination is most likely to exhibit antagonism ? (a) Bactericidal + Bactericidal (b) Bactericidal + Bacteriostatic for a highly sensitive organism (c) Bactericidal + Bacteriostatic for a marginally sensitive organism (d) Bacteriostatic + Bacteriostatic

Last Answer : Ans: B

Description : Clarithromycin and erythromycin have very similar spectrums of antimicrobial activity. The major advantage of clarithromytcin is that it (a) Eradicates mycoplasmal infections in a single dose (b ... not inhibit live drug-metabolizing enzymes (e) Acts on methicillin-resistant strains of staphylococci

Last Answer : Ans: C

Description : _____ is when an antimicrobial drug should harm the infectious agent but not the host. a. Selective toxicity b. Toxic dose c. Therapeutic dose d. Chemotherapeutic index

Last Answer : a. Selective toxicity

Description : Choose the correct statement in relation to treatment of urinary tract infection (UTI): A. Majority of UTIs are caused by gram positive bacteria B. Smaller doses of the antimicrobial agent ... drug gets concentrated in urine D. Most acute UTIs are treated with a combination antimicrobial regimen

Last Answer : B. Smaller doses of the antimicrobial agent suffice for lower UTI

Description : Select the antimicrobial drug which is used orally only for urinary tract infection or for bacterial diarrhoeas: A. Nalidixic acid B. Azithromycin C. Bacampicillin D. Pefloxacin

Last Answer : A. Nalidixic acid

Description : Which type of antimicrobial drug combination is most likely to exhibit antagonism: A. Bactericidal + Bactericidal B. Bactericidal + Bacteriostatic for a highly sensitive organism C. Bactericidal + Bacteriostatic for a marginally sensitive organism D. Bacteriostatic + Bacteriostatic

Last Answer : B. Bactericidal + Bacteriostatic for a highly sensitive organism

Description : Antimicrobial drug combinations are aimed at achieving the following except: A. Faster and more complete elimination of the infecting organism B. Treat infection when nature and sensitivity of the infecting organism is not definite C. Prevent emergence of resistant strains D. Prevent superinfection

Last Answer : D. Prevent superinfection

Description : The following is true of anti-H.pylori therapy except: A. It is indicated in all patients of peptic ulcer B. Resistance to any single antimicrobial drug develops rapidly C. Concurrent ... efficacy of the regimen D. Colloidal bismuth directly inhibits H.pylori but has poor patient acceptability

Last Answer : A. It is indicated in all patients of peptic ulcer

Description : A fixed dose combination preparation meant for internal use must not contain the following class of drug: A. Thiazide diuretic B. Fluoroquinolone antimicrobial C. Corticosteroid D. H2 blocker

Last Answer : C. Corticosteroid

Description : An oil which contains cyclic fatty acids and once used in the treatment of leprosy is (A) Elaidic oil (B) Rapeseed oil (C) Lanoline (D) Chaulmoogric oil

Last Answer : Answer : D

Description : A single dose rifampin + ofloxacin + minocycline treatment has been recommended for: A. All cases of paucibacillary leprosy B. All relapse cases of paucibacillary leprosy C. Single skin lesion paucibacillary leprosy D. None of the above

Last Answer : C. Single skin lesion paucibacillary leprosy

Description : Multidrug therapy with dapsone + rifampin ± clofazimine is the treatment of choice for: A. Multibacillary leprosy B. Paucibacillary leprosy C. Dapsone resistant leprosy D. All forms of leprosy

Last Answer : D. All forms of leprosy

Description : Antimicrobial barrier?Acticoat dressings used in the treatment of burn wounds can be left in place for five days. a) antimicrobial barrier dressings can be left in place for?Acticoat up to five days ... ) two days. antimicrobial barrier dressings can be left in?Acticoat place for up to five days.

Last Answer : a) antimicrobial barrier dressings can be left in place for?Acticoat up to five days thus helping to decrease discomfort to the patient, decrease costs of dressing supplies, and decrease nursing time involved in burn dressing changes.

Description : The MOST primary treatment of ANUG in HIV patient is: A. Prescribe antibiotics B. Debridement and antimicrobial rinses C. Gingivoplasty D. Flap surgery

Last Answer : B. Debridement and antimicrobial rinses

Description : Antimicrobial treatment does not alter the course of the following diarrhoeas except: A. Mild enterotoxigenic E.coli diarrhoea B. Campylobacter diarrhoea C. Coeliac disease diarrhoea D. Food poisoning diarrhoea

Last Answer : B. Campylobacter diarrhoea

Description : An adult patient of acute diarrhoea presents with abdominal pain, fever, mucus and blood in stools and is suspected to be suffering from Shigella enteritis. What antimicrobial treatment would be most appropriate: A. No antimicrobial treatment B. Metronidazole C. Norfloxacin D. Chloramphenicol

Last Answer : C. Norfloxacin

Description : As per WHO guidelines, treatment of failure or relapse (category II) patients of smear positive pulmonary tuberculosis differs from that of new cases in the following respect(s): A. All 5 first line antitubercular drugs ... are given in the continuation phase instead of two (HR) D. Both 'A' and 'C'

Last Answer : D. Both 'A' and 'C'

Description : The drug isoniazid is used widely in contemporary medicine to a. Treat tuberculosis. b. Prevent fungal overgrowth in the intestine. c. Clear away wound infections. d. Eliminate infections due to gram-negative bacteria.

Last Answer : a. Treat tuberculosis.

Description : Which of the following is the cause for drug resistance in tuberculosis? A- Mutation B- Transduction C- Transformation D- Conjugation

Last Answer : Mutation

Description : Multidrug resistant (MDR) tuberculosis is defined as resistance to: A. Any two or more antitubercular drugs B. Isoniazid + any other antitubercular drug C. Isoniazid + Rifampin + any one or more antitubercular drugs D. All five first line antitubercular drugs

Last Answer : C. Isoniazid + Rifampin + any one or more antitubercular drugs

Description : Isonicotinic acid hydrazide given in the treatment of tuberculosis may lead to a deficiency of (A) Vitamin A (B) Pyridoxin (C) Folate (D) Inositol

Last Answer : Answer : B

Description : Isonicotinic acid hydrazide given in the treatment of tuberculosis may lead to a deficiency of (A) Vitamin A (B) Pyridoxin (C) Folate (D) Inositol

Last Answer : Answer : D

Description : Spectinomycin is an aminoglycoside-like antibiotic indicated for the treatment of (a) Gram-negative bacillary septicemia (b) Tuberculosis (c) Penicillin-resistant gonococcal infections (d) Syphilis (e) Gram-negative meningitis due to susceptible organisms

Last Answer : Ans: C

Description : Chloramphenicol is particularly effective in the treatment of (a) Diphtheria (b) Tuberculosis (c) Emphysema (d) Rickettsial diseases (e) Streptomyces pyogenes infections

Last Answer : Ans: D

Description : Sterptomycin has no useful activity in the treatment of (a) Bubonic plague (b) Brucellosis (c) Lyme disease (d) Tuberculosis (e) Tularemia

Last Answer : Ans: C

Description : DOTS is a treatment given to patients suffering from – (1) Polio (2) AIDS (3) Hepatitis (4) Tuberculosis

Last Answer : (4) Tuberculosis Explanation: DOTS (Directly Observed Treatment, Short Course), also known as TBDOTS, is the name given to the tuberculosis control strategy recommended by the World ... curative method for treatment of tuberculosis because of its highly efficient and cost-effective strategy.

Description : Streptomycin can NOT be given orally for treatment of tuberculosis because (A) it gets degraded in the GIT (B) it causes severe diarrhoea (C) it causes metallic taste in the mouth (D) it is not absorbed from the GIT

Last Answer : (D) it is not absorbed from the GIT

Description : Under the WHO guidelines for treatment of new cases of tuberculosis, when isoniazid + ethambutol are used in the continuation phase instead of isoniazid + rifampin,, the duration of this phase is: A. 2 months B. 4 months C. 6 months D. 8 month

Last Answer : C. 6 months

Description : What is true of DOTS strategy for treatment of tuberculosis: A. It consists of an initial intensive phase and a later continuation phase B. The dose of antitubercular drugs is reduced ... patient himself is made responsible for administering antitubercular drugs D. All of the above are correct

Last Answer : A. It consists of an initial intensive phase and a later continuation phase

Description : The most important reason for using a combination of chemotherapeutic agents in the treatment of tuberculosis is: A. To prevent development of resistance to the drugs B. To obtain bactericidal effect C. To broaden the spectrum of activity D. To reduce adverse effects of the drugs

Last Answer : A. To prevent development of resistance to the drugs

Description : Occurrence of the following adverse reaction absolutely contraindicates further use of rifampin in the treatment of tuberculosis: A. Respiratory syndrome B. Cutaneous syndrome C. Flu syndrome D. Abdominal syndrome

Last Answer : A. Respiratory syndrome

Description : DOTS is a treatment given to patients suffering from (1) Polio (2) AIDS (3) Hepatitis (4) Tuberculosis

Last Answer : Tuberculosis

Description : Which among the following is used in the treatment of tuberculosis ? (1) Penicillin (2) Aspirin (3) Paracetamol(4) Dettol

Last Answer : Penicillin

Description : The following is true of multidrug therapy of leprosy except: A. It has been highly successful in paucibacillary but not in multibacillary cases B. Relapse rate is very low in both paucibacillary ... use once a month D. Prevalence of lepra reaction is not higher compared to dapsone monotherapy

Last Answer : A. It has been highly successful in paucibacillary but not in multibacillary cases

Description : Currently, monotherapy of leprosy with dapsone is recommended for: A. Paucibacillary leprosy only B. Multibacillary leprosy only C. Both paucibacillary and multibacillary leprosy D. Neither paucibacillary nor multibacillary leprosy

Last Answer : D. Neither paucibacillary nor multibacillary leprosy

Description : Antibacterial agents can be classified with regard to their structure, mechanism of action, and activity pattern against various types of bacterial pathogens. Which of the following ... are both bacteriostatic d. Sulfonamides and trimethoprim act synergistically to inhibit purine synthesis

Last Answer : Answer: a, b, d Penicillins, cephalosporins, and monobactams possess a b-lactam ring of some type and act to bind bacterial division plate proteins, thus inhibiting cell wall ... act in different mechanisms to inhibit protein synthesis, therefore two agents in combination act synergistically

Description : Select the antimicrobial agent that can be used to treat with both methicillin resistant and vancomycin resistant Staphylococcus aureus infection: A. Clarithromycin B. Clindamycin C. Linezolid D. Lincomycin

Last Answer : C. Linezolid